Research output per year
Research output per year
Professor, MBBS, MD, PhD, MBA, FRACP, FACP, FRCP (Edin), FRCP (London)
The University of Western Australia (M575), 35 Stirling Highway,
6009 Perth
Australia
Richard Pestell, AO., MBBS, MD, PhD, MBA, FRACP, FACP, FRCP (Edin), FRCP (London) is a clinician scientist who currently serves as the President of the Pennsylvania Cancer and Regenerative Medicine Center, and Member Wistar Institute Cancer Center (Associate), in Philadelphia, USA.
He has been the principal investigator of >$86mMM USD in grants primarily from the NIH, published more than 700 works with >88,000 citations, H index 153).
https://scholar.google.com/citations?view_op=search_authors&mauthors=richard+pestell&hl=en&oi=ao He has authored 1 book, 52 book chapters and delivered 285 invited lectures.
He holds multiple issued patents in cancer diagnostics and treatment.
He led cancer not–for-profits, directed two USA Cancer Centers (Lombardi Comprehensive Cancer Center, and the Sidney Kimmel Cancer Center at Thomas Jefferson University) founded Departments, Institutes and several biotechnology companies. He is past President of INCTR (USA), a global not-for-profit working to impact cancer in the developing world and was founding Director of the Delaware Valley Institute for Clinical and Translational Science (University of Delaware, Thomas Jefferson University, Nemours and Christiana). He was most recently Executive Vice President Thomas Jefferson University, Philadelphia, USA.
He was the Winthrop Fellow at Harvard Medical School and was Clinical Fellow at Massachusetts General Hospital. Dr. Pestell completed his M.B., BS at the University of Western Australia, and conducted clinical training in Internal Medicine, Oncology and Endocrinology. He received M.D. and Ph.D. degrees from Melbourne University, and his MBA from NYU, Stern School of Business.
Dr. Pestell identified key genetic targets for cancer, including cyclins and CCR5. His preclinical studies of cyclin D1 in breast cancer were cited as the basis for the clinical trials of CDK inhibitors, now approved by the FDA for treatment of cancer. His preclinical studies of CCR5 inhibitors are cited as the basis for the current clinical trials of CCR5 inhibitors for cancer.
He has received awards for his research, clinical care and impact on improving health care access including RD Wright Medallion, The Eric Susman Prize in Medicine, Doctor of Medical Sciences, Honoris Causa, University of Melbourne, Doctor Honoris Causa, University of Western Australia and appointment as an Officer of the Order of Australia in the 2019 Queen's Birthday Honors for “distinguished service to medicine, and to medical education, as a researcher and physician in the fields of endocrinology and oncology”. https://en.wikipedia.org/wiki/Richard_Pestell
He previously and or currently served as a member of the Editorial Board of 14 journals and as a Reviewers of >18 funding agencies in >9 countries.
Awards
Principal investigator of federal NIH grants (~ 240 NIH grants https://grantome.com/search?q=@author%20%20Richard%20Pestell), including 3 sequential Program multi-investigator grants (2002-2016 (multi-institution (100-150 investigators) (P30 CA 056036), NIH RO1 and R21 grants. In addition I received multi-state grants (IRG-08-060-02 ), State grants (SAP#4100047652), and both PI and multi investigator grants from the Dept. of Defense, receiving >$85M USD to date
Current Academic Appointments
2017- present 1. President, Pennsylvania Cancer and Regenerative Medicine Center,Doylestown, PA 18902, USA
2018-present 5. Vice President of Academic Affairs, and Dean, Xavier University Medical School, Woodbury, NY, 11797 (June 1-2018-).
2022- 6. Adjunct Professor, University of Western Australia 3/1/2022-2/28/2025
2023 7. Visiting Scientist Garvan Institute
Visiting and Honorary Appointments
2015-2019 Visiting Professor, University of Melbourne, Australia
2017-2019 Visiting Professor with Lee Kong Chian School of Medicine, Nanyang Technological University.
2020- Active Member Global Burden of Disease (Institute of Health Metrics collaborator for Dutch Antilles region).
Clinical Synopsis
Licensure/Boards
1982-1991 Licensed in Australia
1989 Fellow Royal College of Physicians (F.R.A.C.P.) (Australia)
thru 2008 Maintenance of Professional Standards (M.O.P.S.)
thru 2010 Continuing Professional Development (C.P.D.)
1981-current Education Commission for Medical Graduates (E.C.F.M.G.)
1993-current Federal Licensing Exam (F.L.E.X.)
1993 Massachusetts Medical License (Limited)
1996-1999 Illinois Medical License
1996-1999 New York Medical License
2003-2005 District of Columbia Medical License
2006- 2022 Pennsylvania Medical License
2019- current Florida Medical License
Prior Appointments
Thomas Jefferson University
2015-2016 Special Advisor to the President (for Innovation) Thomas Jefferson University.
2014-2015 Executive Vice President, Thomas Jefferson University (TJU), Philadelphia, PA.
2005-2015 Director, Sidney Kimmel Cancer Center, TJU, Philadelphia, PA.
2005-2015 Chairman, Department of Cancer Biology, TJU, Philadelphia, PA. (11/2005)
2005-2015 Head of Oncology Service line, Vice President for Oncology Services, Philadelphia, PA.
2005-2015 Associate Dean, Cancer Programs, Sidney Kimmel Medical College, Philadelphia, PA.
2008-2010 Director, Delaware Valley Institute for Clinical & Translational Science, http://www1.udel.edu/udaily/2009/oct/dvicts103108.html
2005-12/2016 Professor with Tenure, Thomas Jefferson University, Philadelphia, PA.
Georgetown University
2005 Associate Vice President, Georgetown University Medical Center, Washington, DC,
2002-2005 Director, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC
2002-2005 Chairman, Department of Oncology, Georgetown University Medical Center (9/2002)
2002-2005 Francis L. and Charlotte Gragnani Chair, Professor with Tenure, Georgetown University, Washington, DC
Georgetown Hospital and Hospital System Board Membership
2002-2006 Member, Board of Directors, Georgetown University Hospital
2003-2005 Member, Nominating Board, Development and Ethics Committee,
Georgetown University Hospital Board of Directors
2002-2005 Member, Clinical Advisory Committee, Georgetown University Hospital
2002-2005 Member, Medical Executive Committee, Georgetown University Hospital, MedStar Health
2002-2005 Member, MedStar Research Institute Board of Directors
2002-2005. Member, MedStar Health Board’s Quality and Professional Affairs Committee.
International
2002-2005 President, International Network for Cancer Treatment and Research (INCTR) (USA) Albert Einstein College of Medicine New York
1996-2002 Associate Professor then Professor (2001), Chairman, Division of Hormone-Dependent Tumor Biology, Cancer Center Program co-leader, Albert Einstein College of Medicine New York.
1993-1995 Assistant Professor, Department of Medicine, Northwestern University Medical School, Chicago, IL
Academic Memberships
2023- Order of Australia Association (lifetime member).
2021- Elected Member, Sigma Xi (Scientific Research Honor Society)
2019- Member Florida Medical Association
2017-- Member American Medical Association
2011- Elected Fellow, American Association for the Advancement of Science
2009- Elected Member, American College of Physicians
2007- Member, American Australian Association
2005- Elected Member, Royal Society of Medicine (UK) 2005
2004- Member, Advance – Australian Professionals in America
2003- Member, American Society of Clinical Oncology
2000- Elected Member, American Society for Clinical Investigation
1996- American Association for Cancer Research
1994- Honorary Lifetime Member, Wyvern Society (For contribution to medical school teaching)
1992- Member, Endocrine Society of the USA
1990- Member, Australian Association of Consultant Physicians
1986- Member, Endocrine Society of Australia
Past
2015- Member, Knowledge Nation 100
2012-2014 Member, National Medical Association
2009-2011 Member, World Affairs Council of Philadelphia
2009 Member, American Society for Investigative Pathology
2009-2011 Member, New York Academy of Sciences
2009- 2021 Elected Member, College of Physicians of Philadelphia
2007- 2015 Member, American Society Clinical Oncology
2004 Chairman, American Association for Cancer Research, Program Committee, Cell Cycle Section
2002- 2016 Association of American Cancer Institutes
2005- Member, Royal Australian College of Physicians, Research & Education Foundation
2004- Member, American Association for Cancer Research, Finance Committee 1998- American Society for Microbiology
1995- American Society for Biochemistry and Molecular Biology
1999- 2002 International Society for Gene Therapy
1997- 2002 Member, Albert Einstein College of Medicine Cancer Center
1997- 2002 Member, Albert Einstein College of Medicine Diabetes Center
1997- 2002 Member, Albert Einstein College of Medicine Liver Center
1993- 1999 Member, American Federation for Clinical Research
1989- 2000 Member, Australian Society of Medical Research
1987- 1993 Member, International Diabetes Federation
1987- 1991 Member, Medical Association for Prevention of War
1986- 1997 Member, Australian Diabetes Association
1982- 1997 Member, Australian Medical Association
Roles and Responsibilities
Grant Reviewer. Study Section. Reviewers of >18 funding agencies in >9 countries. Susan Komen Breast Cancer Foundation:1998-Reviewer, Breast Cancer Research and Education, 1999 Chair, Tumor Cell Biology Study Section., 2001-2008, Co-Chair, Tumor Cell Biology Study Section Department of Defense Study Section: Ovarian Cancer Research Program, November 1999, Breast cancer study section Cell Biology, 1 (CBY-1), panel, DOD FY2000 (Breast Cancer Program), August 14-15, 2000, State of New York EMPIRE Grants and Fellowships study section, 1998-present, New York State Health Research Science Board and New York State Department of Health Grant Review Board member, 2001, Department of Veterans Affairs, Medical Research Service, Merit Review Grants (United States), Ad hoc reviewer, 1998, 1999, 2000-present, National Science Foundation, Ad Hoc, 1998-current, Raine Medical Research Foundation (Australia), 1999-current, Welcome Trust Reviewer, 1999-current, Juvenile Diabetes Research Foundation International Review Board, Member, 1998-current, Association for International Cancer Research (United Kingdom), 2001-current, Binational Science Foundation (Israel), 2008. Merieux Alliance Grant Review (France), 2009. Health Research Board (Ireland), 2013 Israel Science Foundation, 2013, Czech Science Foundation, 2013, Italian Ministry of Health 2014- present, Florida State Department of Health 2014- present, Medical Research Council UK 2015- present Fondation Contre le Cancer 2015, University of Leuven, Belgium 2022-
NIH.
1.1998- present Subcommittee A NCI Cancer Centers P30 grants (reviewer since)
Grant Reviewer: NCI Cancer Center Reviewer – Subcommittee A. Site Visits
NIH Reviewer site visit Reviewer (subset of visits)
Program Project (NCI, Indiana University Cancer Center) - 12/1998
NCI site visit reviewer, NIH-lab of Cellular Oncology - 5/1999, NIH Laboratory of Pathology - 11/17/02
NCI site visit reviewer, University of Pennsylvania Cancer Center, 6/2004
NCI site visit reviewer, University of California San Francisco Cancer Center, CA., 2/2012
NCI site visit reviewer, University of Kansas, February 8, 2017
NCI site visit reviewer, City of Hope, CA., October 3/4, 2017
NCI site visit reviewer, Sloan Kettering Cancer Center, May/10/2018
NCI site visit reviewer, Duncan Cancer Center, Texas., Feb/25/2020
NCI site visit reviewer, O’Neal Cancer Center, Alabama., October/5/2021
NCI site visit reviewer, Roswell Park Cancer Center Site Visit Sep 18-20, 2023
Boards
National and International Boards
2000-2003 Vascular Endothelial Growth Factor (VEGF) Educational Resource Network (VERN), Faculty Member
2002 Member, Medical Advisory Council, American Cancer Society, Mid-Atlantic Division
2002- 2004 Member, Breast Health Advisory Council, Susan G. Komen Foundation
2003-2005 Susan G. Komen Breast Cancer Foundation Task Force, Advisory Panel (Chair, Basic & Translational)
2003-2004 The Advisory Board
2003- 2005 Georgetown University, Lombardi Comprehensive Cancer Center, (R. Clarke, PI) – Cooperative
Grants for Nutritional Modulation of Genetic Pathways Leading to Cancer.
2003-2005 International Network for Cancer Treatment and Research (INCTR), President
2004-2005 Susan G. Komen Breast Health Advisory Council
2004-2005 D.C. Cancer Consortium, Steering Committee
2004 St. Jude Children’s Research Hospital, Dept. of Biochemistry, Review Panel
2004-2008 Honorary Board of Advisors, National Student Leadership Foundation
2004-2009 American Association for Cancer Research- finance committee
2004-2005 American Association for Cancer Research- annual scientific meeting - scientific program committee
2007-2016 Prevent Cancer Foundation (was Cancer Research and Prevention Foundation); Medical Advisory Board
2007-Present LightSeed Inc. (was AAA Phoenix Inc.,). Founder, Chair of Advisory Board
2009-Present American Australian Association, US Advisory Council
2009 Expert Testimony, United States Senate, Committee on Appropriations, Subcommittee on Departments of Labor, Health and Human Services, Education, and Related Agencies (7/6/2009)
2009- 2010 Member, Pennsylvania Division Board of Directors, American Cancer Society
2011 Member, Medical Advisory Board, CORPUS - Journey Through the Human Body
2011-2020 Member, Medical Advisory Board, the Philadelphia Affiliate of Susan G. Komen for the Cure
2011-2013 Internal Advisory Committee, Delaware Valley Institute for Clinical & Translational Science
2012-2016 National Agency for the Evaluation of Universities and Research Institutes (ANVUR)
2014-2019 Basser Board, Basser Research Center, University of Pennsylvania
2018-2019 Member of Board of Directors of CytoDyn Inc.
2023-present Hungarian Government International Advisory Board, Hungarian Research Network (previously E.tv.s Lor.nd Research Network).
Cancer Center Board Member
2001-2005 EAB Roswell Park Cancer Institute, (NCI Designated Cancer Center) Colon Cancer Program
2001-2005 EAB Roswell Park Cancer Institute, Department of Pharmacology and Therapeutics
2003-2007 Howard University Cancer Center, External Scientific Advisory Board
2004-2010 Hollings Cancer Center, (NCI Designated Cancer Center) External Advisory Board, Charleston, South Carolina
2009-2016 Boston University Cancer Center, (NCI Designated Cancer Center) External Advisory Board, Boston, Massachusetts
2010-2017 Cancer Therapy and Research Center, The University of Texas Health Science Center at San Antonio, Texas (NCI Designated Cancer Center)
2011-2015 University of Hawaii Cancer Center, (NCI Designated Cancer Center) consultant special advisor to and member of External Scientific Advisory Board
2011-2016 Member, External Advisory Board, Breakthrough Breast Cancer Research Unit, Manchester, UK
2012-2017 Member, External Advisory Board, Cancer Institute of New Jersey, (NCI Designated Cancer Center)
2014- 2019 Member, External Advisory Board Institute of Bio-Organic Chemistry, Moscow, Russia.
2020-present Chair-Scientific Advisory Board-Chair of The University of Texas MD Anderson Cancer Center SPORE in Breast Cancer.
Consulting Boards
2000-2004 National Cancer Institute Health Care Ventures (advisory board novel cancer therapeutics)
2008 Primary Insight, Inc; A subsidiary of The Bear Stearns Companies.
2013 Clarion Healthcare, LLC – Participation in Market Research Studies
2013 Stratas-Partners – Independent Healthcare Consulting Firm. Basel, Switzerland.
2013 Covidien – Lung Solution Clinical Advisory Board. Boston, MA.
2014 MEDACorp. Boston, MA.
2014 Gerson Lehrman Group, Inc. Austin, TX.
2015 Kantar Health
2015 Novartis consulting group
2015- GroupH (independent management consulting company)
2015 Medtronic
2016- SEAK expert witness patents and other medical legal consulting
2016- Deloitte- Clinical Challenge Panel (State and National Cancer programs)
2018- Xavier University School of Medicine (Medical School curriculum reform- research, innovation, entrepreneurship).
RESEARCH: Reviewer.
Active Journal Reviewer (28). Science, Cancer Cell, Cell Metabolism, Nature Medicine, EMBO Journal, Proceedings of the National Academy of Science USA, Molecular and Cellular Biology, Molecular and Cellular Endocrinology, Journal of Biological Chemistry, Cancer Research, FASEB Journal, Journal of Cell Physiology, Journal of Clinical Investigation, Cell Growth and Differentiation, Endocrinology, Oncogene, European Journal of Biochemistry, Cancer Detection and Prevention, European Journal of Endocrinology, American Journal of Pathology, American Journal of Physiology – Cell Physiology, Journal of Clinical Endocrinology and Metabolism, Brain Research, Nucleic Acids Research,Expert Review of Anticancer Therapy, BMC Cancer, Cancers
Editorial Board
Editorial Boards. (previously and or currently member of editorial board of 14 journals, including Cancer Research, Senior Editor of IJBCB and active editor of Cancers). Editorial Boards. Cancer Research, Senior Editor 2004-2008, Journal of Biological Chemistry, Member, 2002-2007, Trends in, Endocrinology and Metabolism, Member, 2002-2009, International Journal of Oncology, Member, 2001-Present, Frontiers in Bioscience, Member, 1999-Present, Pediatric Pathology and Molecular Medicine, Member, 1999-, Cancer Research, Member Editorial Board, 2003-2004, Current Cancer Therapy Reviews, Member, 2004-, The Lancet Oncology, 2005-Present (Journal Advocate), American Journal of Pathology, Review Editor, 2008-2015, International Journal of Biochemistry and Cell Biology, U.S. Editor, 2009-2016, H Journal, 2012-Present, American & Russian Bioscience, 2013, Oncotarget 2014-2015, Cancers 2020-
Special Editorial Assignments. Contributing Elected Faculty, Member, Faculty of 1000 Biology (Cell Signaling) (1/60 elected members worldwide), Managing Editor, Frontiers in Bioscience "Cell-cycle dysregulation in disease" (10 chapters), 1999-Present, Cancer Research, Senior Editor, 2004
Community Service
2010-Present Founding Member, National Museum of American Jewish History
2012-2015 Board Member Chamber Orchestra of Philadelphia
2012- FIDF
2011 American Cancer Society Laureate Society Invitation Committee
2012-2015 Member, Historic St. Peter’s Church Preservation Corporation
2012- Chair – The Chamber Orchestra of Philadelphia Gala
2013 Event Committee Member – Rabin Award Dinner (March 7), Philadelphia-Israel Chamber of Commerce].
2020- Jewish Federation of Greater Philadelphia
2021 Queens College Sugden Society
2022 The Florey Society
Education Synopsis
Industry, Technology and Innovation
Innovation and Industry synopsis
Diversity
Diversity Synopsis
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review