Richard Lake

Adjunct Professor

  • The University of Western Australia (M570), 35 Stirling Highway,

    6009 Perth

    Australia

  • 5929 Citations
  • 32 h-Index
1996 …2022
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Personal profile

Research

NK cells as the missing link between anti-cancer chemotherapy and CD8 T cell responses
Immunotherapy Plus Chemotherapy Boosts Mesothelioma Treatment Effectiveness

Keywords

  • Cancer
  • Immunology
  • Molecular biology

Fingerprint Dive into the research topics where Richard Lake is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 42 Similar Profiles
Neoplasms Medicine & Life Sciences
Mesothelioma Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences
Asbestos Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Cross-Priming Medicine & Life Sciences
Neoplasm Antigens Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1996 2019

112 Downloads (Pure)

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Zemek, R., de Jong, E., Chin, M., Schuster, I., Fear, V., Casey, T., Forbes, C., Dart, S., Leslie, C., Zaitouny, A., Small, M., Boon, L., Forrest, A. R. R., O Muiri, D., Degli-Esposti, M., Millward, M., Nowak, A., Lassmann, T., Bosco, A., Lake, R. & 1 othersLesterhuis, W., 17 Jul 2019, In : Science Translational Medicine. 11, 501, 14 p., eaav7816.

Research output: Contribution to journalArticle

Open Access
File
STAT1 Transcription Factor
Tumor Microenvironment
Neoplasms
Toll-Like Receptor 3
Transcriptome
1 Citation (Scopus)

Combination immune checkpoint blockade as an effective therapy for mesothelioma

Fear, V., Tilsed, C. M., Chee, H. E. J., Forbes, C., Casey, T., Solin, J., Lansley, S., Lesterhuis, W., Dick, I., Nowak, A., Robinson, B., Lake, R. & Fisher, S., 30 Jul 2018, In : Oncolmmunology. 14 p., e1494111.

Research output: Contribution to journalArticle

Open Access
Mesothelioma
Neoplasms
Therapeutics
Asbestos
Regulatory T-Lymphocytes
Open Access
Lymphocytes
Mesothelioma
Pleural Effusion
Tumors
Blood
16 Citations (Scopus)
Open Access
Maximum Tolerated Dose
Drug Therapy
Inbred C57BL Mouse
Dexamethasone
Weight Loss

Projects 1997 2022