Research Output per year
Personal profile
Research
NK cells as the missing link between anti-cancer chemotherapy and CD8 T cell responses
Immunotherapy Plus Chemotherapy Boosts Mesothelioma Treatment Effectiveness
Immunotherapy Plus Chemotherapy Boosts Mesothelioma Treatment Effectiveness
Keywords
- Cancer
- Immunology
- Molecular biology
Fingerprint Dive into the research topics where Richard Lake is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 42 Similar Profiles
Neoplasms
Medicine & Life Sciences
Mesothelioma
Medicine & Life Sciences
T-Lymphocytes
Medicine & Life Sciences
Drug Therapy
Medicine & Life Sciences
Asbestos
Medicine & Life Sciences
Immunotherapy
Medicine & Life Sciences
Cross-Priming
Medicine & Life Sciences
Neoplasm Antigens
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 1996 2019
Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment
Aston, W. J., Hope, D. E., Cook, A. M., Boon, L., Dick, I., Nowak, A. K., Lake, R. A. & Lesterhuis, W. J., Jul 2019, In : OncoImmunology. 8 p.Research output: Contribution to journal › Article
Open Access
4
Citations
(Scopus)
357
Downloads
(Pure)
Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
Zemek, R., de Jong, E., Chin, M., Schuster, I., Fear, V., Casey, T., Forbes, C., Dart, S., Leslie, C., Zaitouny, A., Small, M., Boon, L., Forrest, A. R. R., O Muiri, D., Degli-Esposti, M., Millward, M., Nowak, A., Lassmann, T., Bosco, A., Lake, R. & 1 others, 17 Jul 2019, In : Science Translational Medicine. 11, 501, 14 p., eaav7816.Research output: Contribution to journal › Article
Open Access
File
STAT1 Transcription Factor
Tumor Microenvironment
Neoplasms
Toll-Like Receptor 3
Transcriptome
Combination immune checkpoint blockade as an effective therapy for mesothelioma
Fear, V., Tilsed, C. M., Chee, H. E. J., Forbes, C., Casey, T., Solin, J., Lansley, S., Lesterhuis, W., Dick, I., Nowak, A., Robinson, B., Lake, R. & Fisher, S., 30 Jul 2018, In : Oncolmmunology. 14 p., e1494111.Research output: Contribution to journal › Article
Open Access
Mesothelioma
Neoplasms
Therapeutics
Asbestos
Regulatory T-Lymphocytes
1
Citation
(Scopus)
Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors
Chee, J., Watson, M. W., Chopra, A., Nguyen, B., Cook, A. M., Creaney, J., Lesterhuis, W. J., Robinson, B. W., Gary Lee, Y. C., Nowak, A. K., Lake, R. A. & McDonnell, A. M., 5 Dec 2018, In : BMC Research Notes. 11, 1, 6 p., 864.Research output: Contribution to journal › Article
Open Access
Lymphocytes
Mesothelioma
Pleural Effusion
Tumors
Blood
21
Citations
(Scopus)
A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice
Aston, W. J., Hope, D. E., Nowak, A. K., Robinson, B. W., Lake, R. A. & Lesterhuis, W. J., 16 Oct 2017, In : BMC Cancer. 17, 1, 684.Research output: Contribution to journal › Article
Open Access
Maximum Tolerated Dose
Drug Therapy
Inbred C57BL Mouse
Dexamethasone
Weight Loss
Projects 1997 2022
ACRF Centre for Advanced Cancer Genomics (NovaSeq)
Forrest, A., Leedman, P., Lister, R., Lassmann, T., Saunders, C., Farah, C., Robinson, B., Nowak, A., Kees, U., Johns, T., Ganss, R., Erber, W., Lake, R., Millward, M., Ziman, M. & Amanuel, B.
Australian Cancer Research Foundation
30/10/18 → 29/10/21
Project: Research
The MexTAg Collaborative Cross: understanding genetic modifiers in mesothelioma
Lake, R., Fisher, S., Morahan, G., Ram, R., Lesterhuis, W. & Nowak, A.
15/07/18 → 14/07/20
Project: Research
Analysis of T cell receptor diversity in animal models of mesothelioma
Lake, R., Chee, J., Lesterhuis, W., Robinson, B., Fisher, S., Watson, M., Chopra, A. & Holt, R.
1/04/18 → 31/03/21
Project: Research
Identifying immune biomarkers of response to chemotherapy in malignant mesothelioma
McDonnell, A., Nowak, A., Lake, R., Robinson, B. & Cook, A.
1/04/18 → 31/03/20
Project: Research