Ralph Martins

Adjunct Professor

  • The University of Western Australia (M650), 35 Stirling Highway,

    6009 Crawley

    Australia

  • 10444 Citations
  • 51 h-Index
1992 …2018

Research Output 1992 2018

2018
3 Citations
Hearing Loss
Cognition
Hearing
Short-Term Memory
Anxiety

Impact of aging on the auditory system and related cognitive functions: A narrative review

Jayakody, D. M. P., Friedland, P. L., Martins, R. N. & Sohrabi, H. R. 5 Mar 2018 In : Frontiers in Neuroscience. 12, MAR, 125

Research output: Contribution to journalReview article

Open Access
Hearing Loss
Cognition
Dementia
Presbycusis
Population

Investigating a potential role for irisin as a biomarker in the early detection of Alzheimer's disease

Bird, S. M. 2018 (Unpublished)

Research output: ThesisDoctoral Thesis

File
Early Diagnosis
Alzheimer Disease
Biomarkers
Pandemics
Research

KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ϵ4-positive cognitively normal adults with high Aβ-amyloid burden

Porter, T., Burnham, S. C., Doré, V., Savage, G., Bourgeat, P., Begemann, K., Milicic, L., Ames, D., Bush, A. I., Maruff, P., Masters, C. L., Rowe, C. C., Rainey-Smith, S., Martins, R. N., Groth, D., Verdile, G., Villemagne, V. L. & Laws, S. M. 1 Dec 2018 In : Scientific Reports. 8, 1, 2034

Research output: Contribution to journalArticle

Open Access
Amyloid
Atrophy
Alleles
Genotype
Episodic Memory
2017
1 Citations

A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort

Pedrini, S. , Gupta, V. B. , Hone, E. , Doecke, J. , O'Bryant, S. , James, I. , Bush, A. I. , Rowe, C. C. , Villemagne, V. L. , Ames, D. , Masters, C. L. , Martins, R. N. , Savage, G. , Wilson, B. , Bourgeat, P. , Fripp, J. , Gibson, S. , Leroux, H. , McBride, S. , Salvado, O. & 92 others Fenech, M., Francois, M., Barnes, M., Baker, J., Barnham, K., Bellingham, S., Bomke, J., Pejoska, S. B., Buckley, R., Cheng, L., Collins, S., Cooke, I., Cyarto, E., Darby, D., Dore, V., El-Sheikh, D., Faux, N., Fowler, C., Harrington, K., Hill, A., Horne, M., Jones, G., Kamer, A., Killeen, N., Korrel, H., Lamb, F., Lautenschlager, N., Lennon, K., Li, Q. X., Lim, Y. Y., Louey, A., Macaulay, L., Mackintosh, L., Maruff, P., McIlroy, A., Nigro, J., Perez, K., Pertile, K., Restrepo, C., Cardoso, B. R., Rembach, A., Roberts, B., Robertson, J., Rumble, R., Ryan, T., Sach, J., Silbert, B., Thai, C., Trounson, B., Volitakis, I., Vovos, M., Ward, L., Watt, A., Williams, R., Woodward, M., Yates, P., Ugarte, F. Y., Zhang, P., Bird, S., Brown, B., Burnham, S., Chatterjee, P., Cox, K., Fernandez, S., Fernando, B., Gardener, S., Laws, S., Lim, F., Lim, L., Tegg, M., Lucas, K., Martins, G., Porter, T., Rainey-Smith, S., Rodrigues, M., Shen, K., Sohrabi, H., Taddei, K., Taddei, T., Tan, S., Verdile, G., Weinborn, M., Farrow, M., Frost, S., Hanson, D., Hor, M., Kanagasingam, Y., Leifert, W., Lockett, L., Riley, M., Saunders, I. & Thomas, P. 1 Dec 2017 In : Scientific Reports. 7, 1, 14057

Research output: Contribution to journalArticle

Open Access
Interleukin-12
Amyloid
Interleukin-10
Alzheimer Disease
Biomarkers
6 Citations

Alterations in erythrocyte fatty acid composition in preclinical Alzheimer's disease

Goozee, K., Chatterjee, P., James, I., Shen, K., Sohrabi, H. R., Asih, P. R., Dave, P., Ball, B., Manyan, C., Taddei, K., Chung, R., Garg, M. L. & Martins, R. N. 6 Apr 2017 In : Scientific Reports. 7, 9 p., 676

Research output: Contribution to journalArticle

Open Access
Alzheimer Disease
Fatty Acids
Erythrocytes
Amyloid
Area Under Curve

BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF

Lim, Y. Y., Rainey-Smith, S., Lim, Y., Laws, S. M., Gupta, V., Porter, T., Bourgeat, P., Ames, D., Fowler, C., Salvado, O., Villemagne, V. L., Rowe, C. C., Masters, C. L., Zhou, X. F., Martins, R. N. & Maruff, P. Nov 2017 In : International Psychogeriatrics. 29, 11, p. 1825-1834 10 p.

Research output: Contribution to journalArticle

Episodic Memory
Brain-Derived Neurotrophic Factor
Alzheimer Disease
Serum
Homozygote
5 Citations

Beta-amyloid sequelae in the eye: A critical review on its diagnostic significance and clinical relevance in Alzheimer's disease

Shah, T. M., Gupta, S. M., Chatterjee, P., Campbell, M. & Martins, R. N. 1 Mar 2017 In : Molecular Psychiatry. 22, 3, p. 353-363 11 p.

Research output: Contribution to journalReview article

Amyloid
Alzheimer Disease
Biomarkers
Eye Diseases
Brain
2 Citations

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease

Müller, S. , Preische, O. , Sohrabi, H. R. , Gräber, S. , Jucker, M. , Dietzsch, J. , Ringman, J. M. , Martins, R. N. , McDade, E. , Schofield, P. R. , Ghetti, B. , Rossor, M. , Graff-Radford, N. R. , Levin, J. , Galasko, D. , Quaid, K. A. , Salloway, S. , Xiong, C. , Benzinger, T. , Buckles, V. & 5 others Masters, C. L., Sperling, R., Bateman, R. J., Morris, J. C. & Laske, C. 1 Dec 2017 In : Scientific Reports. 7, 1, 1225

Research output: Contribution to journalArticle

Open Access
Alzheimer Disease
Body Mass Index
Mutation
Episodic Memory
Amyloid
7 Citations

Diabetes and Alzheimer's Disease: Can Tea Phytochemicals Play a Role in Prevention?

Fernando, W. M. A. D. B., Somaratne, G., Goozee, K. G., Williams, S., Singh, H. & Martins, R. N. 2017 In : Journal of Alzheimer's disease. 59, 2, p. 481-501 21 p.

Research output: Contribution to journalReview article

8 Citations
Cognitive Reserve
Brain
Education
Neuronal Plasticity
PubMed

Evaluation of Cholinergic Deficiency in Preclinical Alzheimer's Disease Using Pupillometry

Frost, S., Robinson, L., Rowe, C. C., Ames, D., Masters, C. L., Taddei, K., Rainey-Smith, S. R., Martins, R. N. & Kanagasingam, Y. 2017 In : Journal of Ophthalmology. 8 p., 7935406

Research output: Contribution to journalArticle

Open Access
4 Citations

Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease

Brown, B. M. , Sohrabi, H. R. , Taddei, K. , Gardener, S. L. , Rainey-Smith, S. R. , Peiffer, J. J. , Xiong, C. , Fagan, A. M. , Benzinger, T. , Buckles, V. , Erickson, K. I. , Clarnette, R. , Shah, T. , Masters, C. L. , Weiner, M. , Cairns, N. , Rossor, M. , Graff-Radford, N. R. , Salloway, S. , Vöglein, J. & 6 others Laske, C., Noble, J., Schofield, P. R., Bateman, R. J., Morris, J. C. & Martins, R. N. 1 Nov 2017 In : Alzheimer's and Dementia. 13, 11, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Cerebrospinal Fluid
Brain
Mutation
1 Citations

Increased Carbohydrate Intake is Associated with Poorer Performance in Verbal Memory and Attention in an APOE Genotype-Dependent Manner

Gardener, S. L., Rainey-Smith, S. R., Sohrabi, H. R., Weinborn, M., Verdile, G., Fernando, W. M. A. D. B., Lim, Y. Y., Harrington, K., Burnham, S., Taddei, K., Masters, C. L., Macaulay, S. L., Rowe, C. C., Ames, D., Maruff, P. & Martins, R. N. 3 May 2017 In : Journal of Alzheimer's Disease. 58, 1, p. 193-201 9 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Genotype
Carbohydrates
Alleles
Amyloid
2 Citations

Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults

Laws, S. M., Gaskin, S., Woodfield, A., Srikanth, V., Bruce, D., Fraser, P. E., Porter, T., Newsholme, P., Wijesekara, N., Burnham, S., Doré, V., Li, Q. X., Maruff, P., Masters, C. L., Rainey-Smith, S., Rowe, C. C., Salvado, O., Villemagne, V. L., Martins, R. N. & Verdile, G. 1 Dec 2017 In : Scientific Reports. 7, 1, 9766

Research output: Contribution to journalArticle

Open Access
Insulin Resistance
Type 2 Diabetes Mellitus
Alzheimer Disease
Episodic Memory
Executive Function
2 Citations

Intense resistance exercise increases peripheral brain-derived neurotrophic factor

Marston, K. J., Newton, M. J., Brown, B. M., Rainey-Smith, S. R., Bird, S., Martins, R. N. & Peiffer, J. J. 1 Oct 2017 In : Journal of Science and Medicine in Sport. 20, 10, p. 899-903 5 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Hypertrophy
Lactic Acid
Fatigue
Serum
1 Citations

Multiple Mechanisms Linking Type 2 Diabetes and Alzheimer's Disease: Testosterone as a Modifier

Asih, P. R., Tegg, M. L., Sohrabi, H., Carruthers, M., Gandy, S. E., Saad, F., Verdile, G., Ittner, L. M. & Martins, R. N. 2017 In : Journal of Alzheimer's disease. 59, 2, p. 445-466 22 p.

Research output: Contribution to journalReview article

2 Citations

Plasma Amyloid-β Peptides in Type 2 Diabetes: A Matched Case-Control Study

Peters, K. E., Davis, W. A., Taddei, K., Martins, R. N., Masters, C. L., Davis, T. M. E. & Bruce, D. G. 3 Feb 2017 In : Journal of Alzheimer's Disease. 56, 3, p. 1127-1133 7 p.

Research output: Contribution to journalArticle

Amyloid beta-Peptides
Amyloid
Type 2 Diabetes Mellitus
Case-Control Studies
Alzheimer Disease
4 Citations

Retinal vascular and structural changes are associated with amyloid burden in the elderly: Ophthalmic biomarkers of preclinical Alzheimer's disease

Golzan, S. M., Goozee, K., Georgevsky, D., Avolio, A., Chatterjee, P., Shen, K., Gupta, V., Chung, R., Savage, G., Orr, C. F., Martins, R. N. & Graham, S. L. 1 Mar 2017 In : Alzheimer's Research and Therapy. 9, 1, 13

Research output: Contribution to journalArticle

Open Access
Retinal Vessels
Amyloid
Alzheimer Disease
Biomarkers
Retinal Ganglion Cells
4 Citations

Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women

Bates, K. A., Sohrabi, H. R., Rainey-Smith, S. R., Weinborn, M., Bucks, R. S., Rodrigues, M., Beilby, J., Howard, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S. S., Foster, J. K., Martins, I. J., Lautenschlager, N. T., Mastaglia, F. L., Gandy, S. E. & Martins, R. N. 4 Mar 2017 In : International Journal of Neuroscience. 127, 3, p. 243-252 10 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Cognition
Cross-Sectional Studies
Verbal Learning
Serum

Study protocol of the Intense Physical Activity and Cognition study: The effect of high-intensity exercise training on cognitive function in older adults

Brown, B. M., Rainey-Smith, S. R., Castalanelli, N., Gordon, N., Markovic, S., Sohrabi, H. R., Weinborn, M., Laws, S. M., Doecke, J., Shen, K., Martins, R. N. & Peiffer, J. J. 1 Nov 2017 In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 4, p. 562-570 9 p.

Research output: Contribution to journalArticle

Open Access
Cognition
Exercise
Dementia
Brain
Randomized Controlled Trials

Understanding the Link between Dementia and Diabetes

Martins, R. N. 2017 In : Journal of Alzheimer's disease. 59, 2, p. 389-392 4 p.

Research output: Contribution to journalEditorial

2016
8 Citations

A-related memory decline in APOE epsilon 4 noncarriers: Implications for Alzheimer disease

Lim, Y. Y., Laws, S. M., Villemagne, V. L., Pietrzak, R. H., Porter, T., Ames, D., Fowler, C., Rainey-Smith, S., Snyder, P. J., Martins, R. N., Salvado, O., Bourgeat, P., Rowe, C. C., Masters, C. L. & Maruff, P. 26 Apr 2016 In : Neurology. 86, 17, p. 1635-1642 8 p.

Research output: Contribution to journalArticle

9 Citations

Cerebral amyloid-β accumulation and deposition following traumatic brain injury-A narrative review and meta-analysis of animal studies

Bird, S. M., Sohrabi, H. R., Sutton, T. A., Weinborn, M., Rainey-Smith, S. R., Brown, B., Patterson, L., Taddei, K., Gupta, V., Carruthers, M., Lenzo, N., Knuckey, N., Bucks, R. S., Verdile, G. & Martins, R. N. 2016 In : Neuroscience and Biobehavioral Reviews. 64, p. 215-228 14 p.

Research output: Contribution to journalArticle

Amyloid
Meta-Analysis
Neurodegenerative Diseases
Alzheimer Disease
Brain Diseases
3 Citations

Cerebral Glucose Metabolism is Associated with Verbal but not Visual Memory Performance in Community-Dwelling Older Adults

Gardener, S. L., Sohrabi, H. R., Shen, K. K., Rainey-Smith, S. R., Weinborn, M., Bates, K., Shah, T., Foster, J. K., Lenzo, N., Salvado, O., Laske, C., Laws, S. M., Taddei, K., Verdile, G. & Martins, R. 10 May 2016 In : Journal of Alzheimer's Disease. 52, 2, p. 661-672 12 p.

Research output: Contribution to journalArticle

Independent Living
Deoxyglucose
Positron-Emission Tomography
Glucose
Amygdala
6 Citations

Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease

Muenchhoff, J., Poljak, A., Thalamuthu, A., Gupta, V. B., Chatterjee, P., Raftery, M., Masters, C. L., Morris, J. C., Bateman, R. J., Fagan, A. M., Martins, R. & Sachdev, P. S. 6 Jul 2016 In : Scientific Reports. 6, p. 1-11 11 p., 29078

Research output: Contribution to journalArticle

Open Access
Proteome
Alzheimer Disease
Proteins
Lipid Metabolism
Blood Vessels
30 Citations

Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study

Burnham, S. C., Bourgeat, P., Doré, V., Savage, G., Brown, B., Laws, S., Maruff, P., Salvado, O., Ames, D., Martins, R. N., Masters, C. L., Rowe, C. C. & Villemagne, V. L. Sep 2016 In : The Lancet Neurology. 15, 10, p. 1044-1053

Research output: Contribution to journalArticle

Longitudinal Studies
Alzheimer Disease
Pathology
Amyloid
Life Style
14 Citations

Curcumin and cognition: A randomised, placebo-controlled, double-blind study of community-dwelling older adults

Rainey-Smith, S. R., Brown, B. M., Sohrabi, H. R., Shah, T., Goozee, K. G., Gupta, V. B. & Martins, R. N. 2016 In : British Journal of Nutrition. 115, 12, p. 2106-2113 8 p.

Research output: Contribution to journalArticle

Independent Living
Curcumin
Double-Blind Method
Cognition
Placebos
37 Citations

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease

Goozee, K. G., Shah, T. M., Sohrabi, H. R., Rainey-Smith, S. R., Brown, B., Verdile, G. & Martins, R. 14 Feb 2016 In : British Journal of Nutrition. 115, 3, p. 449-465 17 p.

Research output: Contribution to journalArticle

Open Access
Curcumin
Alzheimer Disease
Biological Availability
Dementia
Anti-Inflammatory Agents
3 Citations

Exploring the bi-directional relationship between sleep and beta-amyloid

Brown, B. M., Rainey-Smith, S. R., Bucks, R. S., Weinborn, M. & Martins, R. N. Nov 2016 In : Current Opinion in Psychiatry. 29, 6, p. 397-401 5 p.

Research output: Contribution to journalArticle

Amyloid
Sleep
Brain
Polysomnography
Longitudinal Studies
5 Citations

High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease

Francois, M., Fenech, M. F., Thomas, P., Hor, M., Rembach, A., Martins, R. N., Rainey-Smith, S. R., Masters, C. L., Ames, D., Rowe, C. C., Macaulay, S. L., Hill, A. F. & Leifert, W. R. 2016 In : Current Alzheimer Research. 13, 7, p. 787-799 13 p.

Research output: Contribution to journalArticle

7 Citations

Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging

Gupta, V. B., Doecke, J. D., Hone, E., Pedrini, S., Laws, S. M., Thambisetty, M., Bush, A. I., Rowe, C. C., Villemagne, V. L., Ames, D., Masters, C. L., Macaulay, S. L., Rembach, A., Rainey-Smith, S. R. & Martins, R. N. 2016 In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 3, p. 18-26 9 p.

Research output: Contribution to journalArticle

Open Access
Clusterin
Life Style
Alzheimer Disease
Biomarkers
Apolipoprotein E4
11 Citations

Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

Chatterjee, P., Lim, W. L. F., Shui, G., Gupta, V. B., James, I., Fagan, A. M., Xiong, C., Sohrabi, H., Taddei, K., Brown, B. M., Benzinger, T., Masters, C., Snowden, S. G., Wenk, M. R., Bateman, R. J., Morris, J. C. & Martins, R. N. 2016 In : Journal of Alzheimer's Disease. 50, 3, p. 887-894 8 p.

Research output: Contribution to journalArticle

Sphingolipids
Phospholipids
Alzheimer Disease
Mutation
Cerebrospinal Fluid
2 Citations

SFRP-mediated Wnt sequestration as a potential therapeutic target for Alzheimer's disease

Warrier, S., Marimuthu, R., Sekhar, S., Bhuvanalakshmi, G., Arfuso, F., Das, A. K., Bhonde, R., Martins, R. & Dharmarajan, A. 2016 In : International Journal of Biochemistry and Cell Biology. 75, p. 104-111 8 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Neurodegenerative Diseases
Wnt Receptors
Amyloid beta-Peptides
beta Catenin
16 Citations

Subjective memory decline predicts greater rates of clinical progression in preclinical Alzheimer's disease

Buckley, R. F., Maruff, P., Ames, D., Bourgeat, P., Martins, R., Masters, C. L., Rainey-Smith, S., Lautenschlager, N., Rowe, C. C., Savage, G., Villemagne, V. L. & Ellis, K. A. Jul 2016 In : Alzheimer's and Dementia. 12, 7, p. 796-804 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Episodic Memory
Amyloid
Life Style
Biomarkers
2 Citations

The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity

Porter, T., Bharadwaj, P., Groth, D., Paxman, A., Laws, S. M., Martins, R. & Verdile, G. 2 Feb 2016 In : Journal of Alzheimer's Disease. 50, 3, p. 895-905 11 p.

Research output: Contribution to journalArticle

Open Access
File
Amyloid
Amyloidogenic Proteins
Aptitude
Atomic Force Microscopy
Fluorescence
10 Citations

The effects of testosterone supplementation on cognitive functioning in older men

Wahjoepramono, E. J., Asih, P., Aniwiyanti, V., Taddei, K., Dhaliwal, S. S., Fuller, S. J., Foster, J., Carruthers, M., Verdile, G., Sohrabi, H. R. & Martins, R. 2016 In : CNS and Neurological Disorders - Drug Targets. 15, 3, p. 337-343 7 p.

Research output: Contribution to journalArticle

Open Access
File
Testosterone
Placebos
Therapeutics
Cognition
Depression
10 Citations

The Relationship between Sleep Quality and Brain Amyloid Burden

Brown, B. M., Rainey-Smith, S., Villemagne, V. L., Weinborn, M., Bucks, R., Sohrabi, H. R., Laws, S. M., Taddei, K., Macaulay, L., Ames, D., Fowler, C., Maruff, P., Masters, C. L., Rowe, C. C. & Martins, R. 1 May 2016 In : SLEEP. 39, 5, p. 1063-1068

Research output: Contribution to journalArticle

Open Access
Amyloid
Sleep
Brain
Apolipoproteins E
Alleles
4 Citations

Validation and characterization of a novel peptide that binds monomeric and aggregated β-amyloid and inhibits the formation of neurotoxic oligomers

Barr, R. K., Verdile, G., Wijaya, L. K., Morici, M., Taddei, K., Gupta, V. B., Pedrini, S., Jin, L., Nicolazzo, J. A., Knock, E., Fraser, P. E. & Martins, R. 8 Jan 2016 In : Journal of Biological Chemistry. 291, 2, p. 547-559 13 p.

Research output: Contribution to journalArticle

Open Access
Oligomers
Amyloid
Peptides
Alzheimer Disease
Brain
2015
15 Citations

Alzheimer's disease normative cerebrospinal fluid biomarkers validated in pet amyloid-β characterized subjects from the Australian imaging, biomarkers and lifestyle (AIBL) study

Li, Q. X. , Villemagne, V. L. , Doecke, J. D. , Rembach, A. , Sarros, S. , Varghese, S. , Mcglade, A. , Laughton, K. M. , Pertile, K. K. , Fowler, C. J. , Rumble, R. L. , Trounson, B. O. , Taddei, K. , Rainey-Smith, S. R. , Laws, S. M. , Robertson, J. S. , Evered, L. A. , Silbert, B. , Ellis, K. A. , Rowe, C. C. & 6 others Macaulay, S. L., Darby, D., Martins, R., Ames, D., Masters, C. L. & Collins, S. 28 Aug 2015 In : Journal of Alzheimer's Disease. 48, 1, p. 175-187

Research output: Contribution to journalArticle

Pets
Amyloid
Cerebrospinal Fluid
Life Style
Alzheimer Disease
9 Citations

Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity

Nik, S. H. M., Newman, M., Wilson, L., Ebrahimie, E., Wells, S., Musgrave, I., Verdile, G., Martins, R. & Lardelli, M. 1 Jul 2015 In : Human Molecular Genetics. 24, 13, p. 3662-3678 17 p.

Research output: Contribution to journalArticle

Open Access
Unfolded Protein Response
Amyloid Precursor Protein Secretases
Alzheimer Disease
Aptitude
Peptides
18 Citations

APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals - A cross-sectional observational study

Cysique, L. A. J., Hewitt, T., Croitoru-Lamoury, J., Taddei, K., Martins, R., Chew, C. S. N., Davies, N. N. W. S., Price, P. J. S. & Brew, B. J. 1 Apr 2015 In : BMC Neurology. 15, 1, p. 1-8

Research output: Contribution to journalArticle

Open Access
Observational Studies
Cerebrospinal Fluid
Cross-Sectional Studies
HIV
Alzheimer Disease
5 Citations

Bone mineral density, adiposity, and cognitive functions

Sohrabi, H. R. , Bates, K. , Weinborn, M. , Bucks, R. , Rainey-Smith, S. R. , Rodrigues, M. A. , Bird, S. , Brown, B. M. , Beilby, J. , Howard, M. O. , Criddle, A. , Wraith, M. , Taddei, K. , Martins, G. , Patón, A. C. , Shah, T. , Dhaliwal, S. S. , Mehta, P. D. , Foster, J. K. , Martins, I. & 4 others Lautenschlager, N., Mastaglia, F. L., Laws, S. M. & Martins, R. 18 Feb 2015 In : Frontiers in Aging Neuroscience. 7, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
Adiposity
Bone Density
Cognition
Verbal Learning
Apolipoproteins E
16 Citations

Comparison of MR-less PiB SUVR quantification methods

Bourgeat, P., Villemagne, V. L., Dore, V., Brown, B., Macaulay, S. L., Martins, R., Masters, C. L., Ames, D., Ellis, K., Rowe, C. C., Salvado, O. & Fripp, J. 2015 In : Neurobiology of Aging. 36, S1, p. S159-S166

Research output: Contribution to journalArticle

Atlases
Positron-Emission Tomography
Magnetic Resonance Imaging
Amyloid
Alzheimer Disease
2 Citations

Decreased platelet APP isoform ratios in autosomal dominant Alzheimer’s disease: Baseline data from a DIAN cohort subset

Chatterjee, P., Gupta, V. B., Fagan, A. M., Jasielec, M. S., Xiong, C., Sohrabi, H. R., Dhaliwal, S., Taddei, K., Bourgeat, P., Brown, B., Benzinger, T., Bateman, R. J., Morris, J. C. & Martins, R. 2015 In : Current Alzheimer Research. 12, 2, p. 157-164

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Protein Isoforms
Blood Platelets
Mutation
4 Citations

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

Laske, C., Sohrabi, H. R., Jasielec, M. S., Müller, S. P., Koehler, N. K. U., Gräber, S., Förster, S. L., Drzezga, A. E., Mueller-Sarnowski, F., Danek, A., Jucker, M., Bateman, R. J., Buckles, V. D., Saykin, A. J., Martins, R. & Morris, J. C. 2015 In : BioMed Research International. 2015, Article ID 828120, p. 1-7

Research output: Contribution to journalArticle

Open Access
Dementia
Alzheimer Disease
Data storage equipment
Mutation
Geriatrics
7 Citations

Follow-up plasma apolipoprotein e levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort

Gupta, V. B., Wilson, A. C., Burnham, S. C., Hone, E., Pedrini, S., Laws, S. M., Lim, W. L. F., Rembach, A. R., Rainey-Smith, S. R., Ames, D. J., Cobiac, L., Macaulay, S. L., Masters, C., Rowe, C. C., Bush, A. I. & Martins, R. 20 Feb 2015 In : Alzheimer's Research and Therapy. 7, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Open Access
Apolipoproteins
Apolipoproteins E
Life Style
Biomarkers
Alzheimer Disease
58 Citations

Innovative diagnostic tools for early detection of Alzheimer's disease

Laske, C., Sohrabi, H. R., Frost, S. M., López-De-Ipiña, K., Garrard, P., Buscema, M., Dauwels, J., Soekadar, S. R., Mueller, S., Linnemann, C., Bridenbaugh, S. A., Kanagasingam, Y., Martins, R. & O'Bryant, S. E. 2015 In : Alzheimer's and Dementia. 11, 5, p. 561-578

Research output: Contribution to journalArticle

Early Diagnosis
Alzheimer Disease
Hematologic Tests
Neuroimaging
Cerebrospinal Fluid
15 Citations

Phenomenological characterization of memory complaints in preclinical and prodromal alzheimer's disease

Buckley, R. F., Ellis, K. A., Ames, D., Rowe, C. C., Lautenschlager, N., Maruff, P., Villemagne, V. L., Lance Macaulay, S., Szoeke, C., Martins, R., Masters, C. L., Savage, G., Rainey-Smith, S. R., Rembach, A. & Saling, M. M. Jul 2015 In : Neuropsychology. 29, 4, p. 571-581 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Amyloid
Dementia
Life Style
Biomarkers
7 Citations

Self and informant memory concerns align in healthy memory complainers and in early stages of mild cognitive impairment but separate with increasing cognitive impairment

Buckley, R., Saling, M., Ellis, K., Rowe, C., Maruff, P., Macaulay, L. S., Martins, R., Masters, C., Savage, G., Rainey-Smith, S., Rembach, A. & Ames, D. 2015 In : Age and Ageing. 44, 6, p. 1012-1019

Research output: Contribution to journalArticle

Self Report
Cognitive Dysfunction
Memory Disorders
Interviews
Surveys and Questionnaires