Prudence Hart

Adjunct Professor

  • The University of Western Australia (M560), 35 Stirling Highway,

    6009 Crawley

    Australia

  • 2091 Citations
  • 25 h-Index
20032018
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Research Output 2004 2018

2018

Cellular and molecular mechanisms of vitamin D in food allergy

Poole, A., Song, Y., Brown, H., Hart, P. H. & Zhang, G. . B. 1 Jul 2018 In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3270-3277 8 p.

Research output: Contribution to journalReview article

Open Access
Food Hypersensitivity
Vitamin D
Microbiota
Sunlight
DNA Methylation

Divisions of labour in dendritic cell immune-surveillance and epigenetic mechanisms of immune evasion

Wylie, B. C. 2018 (Unpublished)

Research output: ThesisDoctoral Thesis

File
Immune Evasion
Epigenomics
Dendritic Cells
Immunity
Neoplasms

Investigating the roles of regulatory T cells, mast cells and interleukin-9 in the control of skin inflammation by vitamin D

Gorman, S., Geldenhuys, S., Weeden, C. E., Grimbaldeston, M. A. & Hart, P. 1 Apr 2018 In : Archives of Dermatological Research. 310, 3, p. 221-230 10 p.

Research output: Contribution to journalArticle

Interleukin-9
Regulatory T-Lymphocytes
Mast Cells
Vitamin D
Inflammation
1 Citations

Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice

McGonigle, T. A., Dwyer, A. R., Greenland, E. L., Scott, N. M., Carter, K. W., Keane, K. N., Newsholme, P., Goodridge, H. S., Pixley, F. J. & Hart, P. H. 1 Jan 2018 In : Journal of Immunology. 200, 1, p. 260-270

Research output: Contribution to journalArticle

Chemotactic Factors
Bone Marrow
Macrophages
Macrophage Colony-Stimulating Factor
Inflammation
2017

Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis

Jones, A. P., Trend, S., Byrne, S. N., Fabis-Pedrini, M. J., Geldenhuys, S., Nolan, D., Booth, D. R., Carroll, W. M., Lucas, R. M., Kermode, A. G. & Hart, P. H. May 2017 In : Clinical & Translational Immunology. 6, 5, e143

Research output: Contribution to journalArticle

Open Access
Regulatory T-Lymphocytes
Multiple Sclerosis
Blood Cells
Therapeutics

Altered regulatory T-cell fractions and Helios expression in Clinically Isolated Syndrome

Jones, A., Trend, S., Byrne, S. N., Fabis-Pedrini, M. J., Geldenhuys, S., Nolan, D., Booth, D. R., Carroll, W. M., Lucas, R. M., Kermode, A. G. & Hart, P. H. Nov 2017 In : Multiple Sclerosis. 23, 13, p. NP7-NP7 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

11 Citations

Circulating immune cells in multiple sclerosis

Jones, A. P., Kermode, A. G., Lucas, R. M., Carroll, W. M., Nolan, D. & Hart, P. H. 1 Feb 2017 In : Clinical and Experimental Immunology. 187, 2, p. 193-203 11 p.

Research output: Contribution to journalReview article

Open Access
File
Multiple Sclerosis
B-Lymphocyte Subsets
T-Lymphocyte Subsets
B-Lymphocytes
T-Lymphocytes
1 Citations

Evolving identification of blood cells associated with clinically isolated syndrome: Importance of time since clinical presentation and diagnostic MRI

Trend, S., Jones, A. P., Geldenhuys, S., Byrne, S. N., Fabis-Pedrini, M. J., Nolan, D., Booth, D. R., Carroll, W. M., Lucas, R. M., Kermode, A. G. & Hart, P. H. 15 Jun 2017 In : International Journal of Molecular Sciences. 18, 6, 1277

Research output: Contribution to journalArticle

Open Access
blood cells
Magnetic resonance
magnetic resonance
Blood Cells
Blood

Expression of MS risk genes in whole blood of CIS patients treated with narrow band UVB phototherapy

Gatt, P., Lucas, R. M., Carroll, W. M., Nolan, D., Cole, J. M., Jones, A. P., Trend, S., Cha, L., Kermode, A. G., Hart, P. H. & Booth, D. R. Nov 2017 In : Multiple Sclerosis. 23, 13, p. NP14-NP14 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

6 Citations

Narrowband UVB phototherapy for clinically isolated syndrome: A trial to deliver the benefits of vitamin D and other UVB-induced molecules

Hart, P. H., Lucas, R. M., Booth, D. R., Carroll, W. M., Nolan, D., Cole, J. M., Jones, A. P. & Kermode, A. G. 24 Jan 2017 In : Frontiers in Immunology. 8, January, 3

Research output: Contribution to journalArticle

Open Access
Phototherapy
Vitamin D
Multiple Sclerosis
Solar System
Sunlight

Narrowband UVB phototherapy for Clinically Isolated Syndrome: Delivering the benefits of all UVB-induced molecules to early MS patients

Hart, P., Kermode, A. G., Lucas, R. M., Booth, D. R., Carroll, W. M., Nolan, D., Cole, J. M., Byrne, S. N., Jones, A. P., Trend, S. & Cha, L. Nov 2017 In : Multiple Sclerosis. 23, 13, p. NP7-NP7 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

McGonigle, T. A., Dwyer, A. R., Greenland, E. L., Scott, N. M., Keane, K. N., Newsholme, P., Goodridge, H. S., Zon, L. I., Pixley, F. J. & Hart, P. H. Dec 2017 In : Experimental hematology. 56, p. 64-68

Research output: Contribution to journalArticle

16,16-Dimethylprostaglandin E2
Dinoprostone
Bone Marrow Cells
Cell Movement
Monocytes

Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight mice

Fleury, N., Feelisch, M., Hart, P. H., Weller, R. B., Smoothy, J., Matthews, V. B. & Gorman, S. 1 Apr 2017 In : Journal of Endocrinology. 233, 1, p. 81-92 12 p.

Research output: Contribution to journalArticle

Radiation
High Fat Diet
Nitric Oxide
Sunlight
Adiposity
4 Citations

The bioenergetics of inflammation: insights into obesity and type 2 diabetes

Keane, K. N., Calton, E. K., Carlessi, R., Hart, P. H. & Newsholme, P. 2017 In : European Journal of Clinical Nutrition. 71, 7, p. 904–912

Research output: Contribution to journalReview article

Type 2 Diabetes Mellitus
Energy Metabolism
Obesity
Inflammation
Leukocytes
2 Citations

Tracking of Vitamin D status from childhood to early adulthood and its association with peak bone mass

Zhu, K., Oddy, W. H., Holt, P., Ping-Delfos, W. C. S., Mountain, J., Lye, S., Pennell, C., Hart, P. H. & Walsh, J. P. 1 Jul 2017 In : American Journal of Clinical Nutrition. 106, 1, p. 276-283 8 p.

Research output: Contribution to journalArticle

Open Access
File
Vitamin D
Bone Density
Bone and Bones
Serum
Photon Absorptiometry

UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow–Differentiated Dendritic Cells

McGonigle, T. A., Keane, K. N., Ghaly, S., Carter, K. W., Anderson, D., Scott, N. M., Goodridge, H. S., Dwyer, A., Greenland, E., Pixley, F. J., Newsholme, P. & Hart, P. H. 1 Sep 2017 In : American Journal of Pathology. 187, 9, p. 2046-2059 14 p.

Research output: Contribution to journalArticle

Dendritic Cells
Bone Marrow
Skin
3-Hydroxyanthranilate 3,4-Dioxygenase
CC Chemokines
18 Citations

Vitamin D over the first decade and susceptibility to childhood allergy and asthma

Hollams, E. M., Teo, S. M., Kusel, M., Holt, B. J., Holt, K. E., Inouye, M., De Klerk, N. H., Zhang, G., Sly, P. D., Hart, P. H. & Holt, P. G. Feb 2017 In : Journal of Allergy and Clinical Immunology. 139, 2, p. 472-481.e9

Research output: Contribution to journalArticle

Vitamin D
Hypersensitivity
Asthma
Eczema
Parturition
1 Citations
Open Access
Vitamin D
Pneumonia
Cholecalciferol
Lung
Diet
2016
4 Citations
Open Access
Regulatory T-Lymphocytes
Vitamin D
Lymph Nodes
Inflammation
Cholecalciferol
4 Citations

Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo

Calapre, L., Gray, E. S., Kurdykowski, S., David, A., Hart, P., Descargues, P. & Ziman, M. 2016 In : BMC Dermatology. 16, 1, p. 6 6 p.

Research output: Contribution to journalArticle

Keratinocytes
Hot Temperature
Apoptosis
Skin
DNA Damage

High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's Disease

Ghaly, S., Murray, K., Baird, A., Martin, K., Prosser, R., Mill, J., Simms, L. A., Hart, P. H., Radford-Smith, G., Bampton, P. A. & Lawrance, I. C. Oct 2016 In : Inflammatory bowel diseases. 22, 10, p. 2456-2464 9 p.

Research output: Contribution to journalArticle

Vitamin D-Binding Protein
Crohn Disease
Albumins
Sunlight
Recurrence
6 Citations
Vitamin D Deficiency
Pyroglyphidae
Pneumonia
Genes
Smooth Muscle
1 Citations

Serum 25-hydroxyvitamin D concentrations and cardiometabolic risk factors in adolescents and young adults

Black, L., Burrows, S., Lucas, R. M., Marshall, C., Huang, R-C., Chan She Ping-Delfos, W., Beilin, L., Holt, P., Hart, P., Oddy, W. & Mori, T. Jun 2016 In : British Journal of Nutrition. 115, 11, p. 1994-2002

Research output: Contribution to journalArticle

Open Access
File
Young Adult
Serum
Insulin Resistance
Homeostasis
Blood Pressure
5 Citations

Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific manner

Roggenbuck, M., Anderson, D., Barfod, K. K., Feelisch, M., Geldenhuys, S., Sørensen, S. J., Weeden, C. E., Hart, P. H. & Gorman, S. 2016 In : Respiratory Research. 17, 1, p. 116 116 p.

Research output: Contribution to journalArticle

Open Access
Microbiota
Vitamin D
Lung
Diet
Ovalbumin
2015
4 Citations

Can skin exposure to sunlight prevent liver inflammation?

Gorman, S., Black, L., Feelisch, M., Hart, P. & Weller, R. 5 May 2015 In : Nutrients. 7, 5, p. 3219-3239

Research output: Contribution to journalReview article

Open Access
dermal exposure
Sunlight
fatty liver
vitamin D
Vitamin D
4 Citations

Comparing the effects of sun exposure and vitamin D supplementation on vitamin D insufficiency, and immune and cardio-metabolic function: The Sun Exposure and Vitamin D Supplementation (SEDS) Study

Hartley, M., Hoare, S., Lithander, F. E., Neale, R. E., Hart, P., Gorman, S., Gies, P. H. F., Sherriff, J. L., Swaminathan, A., Beilin, L., Mori, T., King, L., Black, L., Marshall, K., Xiang, F., Wyatt, C., King, K., Slevin, T. J., Pandeya, N. & Lucas, R. 2015 In : BMC Public Health. 15, 1, p. 1-9

Research output: Contribution to journalArticle

Open Access
Solar System
Vitamin D
Vitamin D Deficiency
Skin Neoplasms
Serum
6 Citations

Cross-presentation of cutaneous melanoma antigen by migratory XCR1+CD103 and XCR1+CD103+ dendritic cells

Wylie, B., Seppanen, E., Xiao, K., Zemek, R., Zanker, D., Prato, S., Foley, B., Hart, P., Kroczek, R. A., Chen, W. & Waithman, J. 2015 In : OncoImmunology. 4, 8, p. 1-11

Research output: Contribution to journalArticle

Cross-Priming
Melanoma-Specific Antigens
Dendritic Cells
Neoplasm Antigens
Skin

Reduced immune responses in chimeric mice engrafted with bone marrow cells from mice with airways inflammation

Scott, N. M., Ng, R. L. X., McGonigle, T. A., Gorman, S. & Hart, P. Nov 2015 In : Inflammation Research. 64, 11, p. 861-873 13 p.

Research output: Contribution to journalArticle

Open Access
File
Bone Marrow Cells
Inflammation
Bone Marrow
Dendritic Cells
Allergens
20 Citations
Open Access
Vitamin D Deficiency
Vitamin D
Smooth Muscle
Muscle
Lung

UV Irradiation of Skin Regulates a Murine Model of Multiple Sclerosis

Geldenhuys, S., Mohammad, M. G., Hui, L., Hassanpour, M., Ng, R., Scott, N. M., Lucas, R., Brown, D. A. & Hart, P. 2015 In : Journal of Multiple Sclerosis. 2, 3, p. 1-5

Research output: Contribution to journalArticle

36 Citations

Vitamin D in fetal development: Findings from a birth cohort study

Hart, P., Lucas, R., Walsh, J., Zosky, G., Whitehouse, A., Zhu, K., Allen, K., Kusel, M. M., Anderson, D. & Mountain, J. 2015 In : Pediatrics. 135, 1, p. e167-e173

Research output: Contribution to journalArticle

2014
11 Citations
Genome-Wide Association Study
Vitamin D
Cohort Studies
Chromosomes
Pregnancy
61 Citations

Immune cell trafficking from the brain maintains CNS immune tolerance

Mohammad, M. G., Tsai, V. W. W., Ruitenberg, M., Hassanpour, M., Li, H., Hart, P., Breit, S. N., Sawchenko, P. E. & Brownl, D. A. 3 Mar 2014 In : The Journal of Clinical Investigation. 124, 3, p. 1228-1241 14 p.

Research output: Contribution to journalArticle

Open Access
37 Citations

Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms

Robinson, M., Whitehouse, A., Newnham, J., Gorman, S., Jacoby, P., Holt, B. J., Serralha, M., Tearne, J., Holt, P., Hart, P. & Kusel, M. 1 Jun 2014 In : Archives of women's mental health. 17, 3, p. 213-219

Research output: Contribution to journalArticle

Open Access
File
Postpartum Depression
Vitamin D
Mothers
Pregnancy
Serum
22 Citations
Open Access
File
Adiposity
Serum
Insulin Resistance
Vitamin D Deficiency
Odds Ratio
20 Citations
Open Access
File
Vitamin D
Young Adult
Depression
Anxiety
Serum
48 Citations

Maternal vitamin D status during pregnancy and bone mass in offspring at 20 years of age: A prospective cohort study

Zhu, K., Whitehouse, A., Hart, P., Kusel, M., Mountain, J., Lye, S., Pennell, C. & Walsh, J. May 2014 In : Journal of Bone and Mineral Research. 29, 5, p. 1088-1095

Research output: Contribution to journalArticle

Open Access
Vitamin D
Bone Density
Cohort Studies
Mothers
Prospective Studies
18 Citations

Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow

Scott, N. M., Ng, R. L., Gorman, S., Norval, M., Waithman, J. & Hart, P. Feb 2014 In : Journal of leukocyte biology. 95, 2, p. 225-232

Research output: Contribution to journalArticle

Open Access
Prostaglandins E
Dinoprostone
Dendritic Cells
Bone Marrow
Bone Marrow Cells
1 Citations

Reply

Zosky, G. R., Hart, P., Whitehouse, A. & Hall, G. 2014 In : Annals of the American Thoracic Society. 11, 8, p. 1337-1338

Research output: Contribution to journalLetter

33 Citations

Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D in mice fed a high-fat diet

Geldenhuys, S., Hart, P., Endersby, R., Jacoby, P., Feelisch, M., Weller, R. B. J. B., Matthews, V. & Gorman, S. 2014 In : Diabetes. 63, 11, p. 3759-3769

Research output: Contribution to journalArticle

High Fat Diet
Vitamin D
Obesity
Radiation
Sunlight

UVR-induced immunosupression

Norval, M. & Hart, P. 2014 Handbook of Photomedicine. Hamblin, M. R. & Huang, Y. Y. (eds.). United States: Taylor & Francis, p. 111-122

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

24 Citations

Vitamin D and immunity

Lucas, R., Gorman, S., Geldenhuys, S. & Hart, P. 2014 In : F1000Prime Reports. 6, p. 1-11

Research output: Contribution to journalArticle

Vitamin D
Immunity
Vitamin D Deficiency
Physiologic Calcification
Microbiota
51 Citations

Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age

Zosky, G., Hart, P., Whitehouse, A., Kusel, M., Ang, W., Foong, R., Chen, L., Holt, P., Sly, P. D. L. & Hall, G. 2014 In : Annals of the American Thoracic Society. 11, 4, p. 571-577

Research output: Contribution to journalArticle

Vitamin D Deficiency
Asthma
Pregnancy
Lung
Mothers
22 Citations
Open Access
10 Citations

Vitamin D status and predictors of serum 25-hydroxyvitamin D concentrations in Western Australian adolescents

Black, L., Burrows, S., Jacoby, P., Oddy, W., Beilin, L., Chan She Ping-Delfos, W., Marshall, C. E., Holt, P., Hart, P. & Mori, T. Oct 2014 In : British Journal of Nutrition. 112, 7, p. 1154-1162

Research output: Contribution to journalArticle

Open Access
File
Vitamin D
Serum
25-hydroxyvitamin D
Linear Models
Consensus
2013
25 Citations

Altered immunity and dendritic cell activity in the periphery of mice after long-term engraftment with bone marrow from ultraviolet-irradiated mice

Ng, R. L. X., Scott, N. M., Strickland, D., Gorman, S., Grimbaldeston, M. A., Norval, M., Waithman, J. & Hart, P. 2013 In : Journal of Immunology. 190, p. 5471-5484

Research output: Contribution to journalArticle

Open Access
1 Citations

Benefits of vitamin D for allergic airways

Hart, P. 2013 In : Clinical and Experimental Allergy. 43, p. 580

Research output: Contribution to journalLetter

11 Citations

Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice

Ng, R. L. X., Scott, N. M., Bisley, J. L., Lambert, M. J., Gorman, S., Norval, M. & Hart, P. Dec 2013 In : Immunology. 140, 4, p. 399-412

Research output: Contribution to journalArticle

Open Access
Dendritic Cells
Bone Marrow
Immunity
Radiation
Gene Expression
13 Citations

Dendritic cells and multiple sclerosis: Disease, tolerance and therapy

Mohammad, M. G., Hassanpour, M., Tsai, V. W. W., Li, H., Ruitenberg, M. J., Booth, D. R., Serrats, J., Hart, P., Symonds, G. P., Sawchenko, P. E., Breit, S. N. & Brown, D. A. 2013 In : INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 14, p. 547

Research output: Contribution to journalLiterature review

Open Access