Associate Professor Peter Noble is a Respiratory Physiologist (PhD 2006) in the School of Human Sciences at The University of Western Australia. Since obtaining his PhD, he was self-funded through several NHMRC Fellowships, the last of which ended in 2016. In 2017, he transitioned into a fulltime teaching/research academic position while continuing to apply for competitive funding. The global hypothesis of his research program is that structural and mechanical abnormalities of the airways independently contribute to the severity of obstructive disease and can be directly targeted to improve patient outcomes. He is presently developing optical coherence tomography as a diagnostic tool for use in patients with asthma.

Unit Coordinator (PHYL3004)

NHMRC

• 2019      Project Grant (CIA, APP1180854, $1,060,200)

‘Unravelling a clinical paradox: why does bronchial thermoplasty work in asthma and how can we improve patient outcomes?’

• 2019      Equipment Grant (CIB, $40,000)

‘Large animal biotelemetry system’

• 2018      Project Grant (CIB, APP1141552, $623,078)

‘Heterogeneity of airway smooth muscle remodelling in asthma’

• 2018      Equipment Grant (CIE, $50,000)

‘Kingfisher 96 Flex nucleic acid/protein purification system’

• 2016      Equipment Grant (CIA, $47,500)

’Philips premium portable CX50 ultrasound system’

• 2015-2017          Project Grant (CIA, APP1077791, $519,830)

‘Ontogeny of the airway smooth muscle layer in health and disease’

• 2014-2017          Project Grant (CID, APP1057759, $1,689,652)

‘Treating Preterm Infants with steroids: when does benefit outweigh cost?’

• 2014-2016          Project Grant (CIC, APP1063068, $791,677)

‘Airway extracellular matrix and smooth muscle in COPD’

• 2014-2016          Development Grant (CIC, APP1076050, $317,111)

‘Development of microscope-in-a-needle devices for improved clinical diagnostics’

• 2013-2016          Career Development Fellowship (CIA, APP1045824, $404,884)

‘Structural and mechanical determinants of airway hyperresponsiveness’

• 2012-2014          Project Grant (CIA, APP1027218, $396,250)

‘Airway smooth muscle and asthma’

• 2008-2011          Early Career Fellowship (CIA, APP513921, $286,016)

‘Investigation on whether changes in lung stretch contributes to respiratory disease’

• 2008-2010          Project Grant (CIB, APP513842, $281,037)

‘Response of human airways to deep inflation in health and disease’

• 2011      Equipment Grant (Co-CI, $52,000)

‘Casmed ForeSight monitor X2 for absolute cerebral and tissue oximetry’

• 2011      Equipment grant (Co-CI, $45,000)

‘Visiopharm new CAST software and stereology microscope’

• 2007      Equipment Grant (Co-CI, $37,000)

‘Leica ASP-200 automated vacuum tissue processor’

Other Funding

• 2020      Channel 7 Telethon Trust (CIC, $129,325.00)

              ‘Nebulised Surfactant: simplifying delivery of the liquid of life for infants with breathing difficulties after birth’

• 2020      Medical Health Infrastructure Research Fund (CIA, $33,298)

• 2020      Sir Charles Gairdner and Osborne Park Health Care Group Research Grant (CIC, $30,000)

‘The relationship between adipose tissue and airway inflammation in asthma’

• 2019      Medical Health Infrastructure Research Fund (CIA, $33,303)

• 2019      Sir Charles Gairdner and Osborne Park Health Care Group Research Grant (CIB, $30,000)

'Increased adipose tissue within the airway wall and its relation to lung function’

• 2019      Sir Charles Gairdner and Osborne Park Health Care Group Research Grant (AI, $30,000)

' Application of an ex-vivo hydrogel model to assess and  reverse airway smooth muscle cell stiffness in COPD’

• 2018      WA Department of Health - Merit Award (CIA, $50,000)

‘A novel physiological program to understand, treat and prevent obstructive airway disease’

• 2018      Sir Charles Gairdner and Osborne Park Health Care Group Research Grant (CIB, $40,000)

'Airway smooth muscle integrin expression in obstructive lung disease’

• 2018      Telethon New Children’s Hospital Research Fund (CIB, $235,102)

‘Promoting normal lung growth, structure and function in congenital diaphragmatic hernia: a transdisciplinary approach’

• 2018      Medical Health Infrastructure Research Fund (CIA, $41,167.00)

• 2018      Sir Charles Gairdner and Osborne Park Health Care Group Research Grant (CIB, $40,000)

‘Adipose tissue within the airway wall and its relation to asthma severity’

• 2017      Medical Health Infrastructure Research Fund (CIA, $33,303)

• 2017      UWA Research Collaboration Award (CIC, $20,000)

• 2017      Hollywood Private Hospital Research Foundation (CIB, $10,000)
• 2016      Medical Research Foundation, Royal Perth Hospital (CIB, $19,642)

• 2016      Asthma Foundation of Western Australia Project Grant (CIB, $40,000)

‘A pilot study examining the molecular determinants of postnatal airway smooth muscle growth’

• 2015      Asthma Foundation of Western Australia New Investigator Project Grant (CIB, $24,300)

‘Intrauterine growth restriction increases airway smooth muscle mass and risk of asthma development’

• 2015      Hollywood Private Hospital Research Foundation (CIB, $7,500)

‘Airway extracellular matrix and smooth muscle in chronic obstructive pulmonary disease’

2014-2015          Telethon New Children’s Hospital Research Fund (CID, $202,885)

• ‘Postnatal steroids and antenatal chorioamnionitis: between the scylla and charybdis of inflammation and apoptosis after preterm birth’

2014-2015          Telethon New Children’s Hospital Research Fund (CID, $68,678)

• ‘Fibre-optic measurement of airway surface liquid pH in children with cystic fibrosis’

2014      Princess Margaret Hospital Foundation (CID, $79,274.47)

‘Fibre-optic measurement of airway surface liquid pH in children with cystic fibrosis and initial testing of pH correcting drugs’

• 2013-2015          BrightSpark Foundation Fellowship (CIA, $437,595.4)

‘The early life origin of asthma: structural and functional abnormalities of the airway wall at birth’ NB: fellowship returned following receipt of NHMRC CDF

• 2012      Medical Health Infrastructure Research Fund (CIA, $14,321)
• 2011      UWA Near Miss Grant (CIA, $70,000)
• 2010      UWA Research Development Award (CIA, $23,052)
• 2007-2008          Raine Medical Research Foundation (CIA, $129,458)

‘Airway adaptation to chronic mechanical strain’ adaptation to chronic mechanical strain’

2015-2016          Senior Research Fellow, The University of Western Australia

·             School of Anatomy, Physiology and Human Biology

·             Centre for Neonatal Research and Education, School of Paediatrics and Child Health

2008-2016          Honorary Research Fellow, Telethon Kids Institute

Division of Clinical Sciences

2013-2015          Assistant Research Professor, The University of Western Australia

·             School of Anatomy, Physiology and Human Biology

·             Centre for Neonatal Research and Education, School of Paediatrics and Child Health

2011-2012          Assistant Research Professor, The University of Western Australia

·             School of Women’s and Infants’ Health

2008-2010          Research Fellow, Telethon Kids Institute

·             Division of Clinical Sciences

2006-2007          Research Associate, The University of Western Australia

·             School of Biomedical, Biomolecular and Chemical Sciences

2006      Research Assistant, The University of Western Australia

·             School of Biomedical, Biomolecular and Chemical Sciences

2001      Research Assistant, The University of Western Australia

·             School of Biomedical, Biomolecular and Chemical Sciences