Personal profile
Biography
Funding overview
Current projects
•Using cellular cultures of smooth muscle to determine the cellular components of responses to stress
•Studying the damage to airways and muscles from patients with chronic obstructive pulmonary disease (COPD)
Potential Student Projects
Looking at human COPD versus controls (PhD)
Teaching overview
Unit Co-ordinator:
PHYL3340 Advanced Cellular Physiology
PHYL3350 Physiological Control Mechanisms
Lecturer:
PHYL2255 Physiology of Human Body Systems
PHYL2260 Physiology of Adaption and Stress
IDNT1121 Foundations of Human and Animal Biology
Graduate Entry Medical Programme (GEMP)
Lab Classes:
PHYL2245 Physiology of Cells
Research
Collaborators
Peter Noble, Institute for Child Health Research (ICHR)
Alan James, Charles Gardener Hospital
Lyn Fernaders, Pharmacology, UWA
Research expertise keywords
- Lung physiology—airway smooth muscle, asthma
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Research output
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Airway narrowing and response to simulated deep inspiration in bronchial segments from subjects with fixed airflow obstruction
Cairncross, A., Jones, R. L., Elliot, J. G., McFawn, P. K., James, A. L. & Noble, P. B., 1 Jan 2020, In: Journal of Applied Physiology. 128, 4, p. 757-767 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Link opens in a new tab Citations (Scopus)6 Downloads (Pure) -
Different structural components of the airway smooth muscle layer determine post-bronchodilator and airway responsiveness in smokers
Cairncross, A., Noble, P., Elliot, J., McFawn, P. & James, A., Mar 2019, In: Respirology. 24, Suppl 1, p. 4 206 p., TO 126.Research output: Contribution to journal › Abstract/Meeting Abstract
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Hyperinflation of bronchi in vitro impairs bronchodilation to simulated breathing and increases sensitivity to contractile activation
Cairncross, A., Noble, P. B. & Mcfawn, P. K., Aug 2018, In: Respirology. 23, 8, p. 750-755 6 p.Research output: Contribution to journal › Article › peer-review
11 Link opens in a new tab Citations (Web of Science) -
Intrinsic airway smooth muscle tone in peripheral airways is determined by the volume fraction of muscle and extracellular matrix
Noble, P., Cairncross, A., James, A., Elliot, J., King, G., Mcparland, B. E., Sanai, F. & McFawn, P., 2018, (Unpublished).Research output: Contribution to conference › Conference presentation/ephemera
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Lessons from ex-vivo studies on small airways: role of intrinsic smooth muscle tone in airway disease
Noble, P., Cairncross, A., Sanai, F., Mcparland, B. E., King, G., McFawn, P., Elliot, J. & James, A., 2017.Research output: Contribution to conference › Conference presentation/ephemera
Projects
- 7 Finished
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Airway Extracellular Matrix and Smooth Muscle in COPD
James, A. (Investigator 01), King, G. (Investigator 02), Noble, P. (Investigator 03), McFawn, P. (Investigator 04) & McParland, B. (Investigator 05)
NHMRC National Health and Medical Research Council
1/01/14 → 30/11/18
Project: Research
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Response of Human Airways to Deep Inflation in Health and Disease
McFawn, P. (Chief Investigator), Noble, P. (Chief Investigator), Mitchell, H. (Chief Investigator) & James, A. (Chief Investigator)
1/01/08 → 31/12/12
Project: Research
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NHMRC Equipment Grant - State-of-the-Art Leica ASP-200 Automated Vacuum Tissue Processor for High Quality Processing of Animal and Human Tissue Samples for Light Microscopy Analysis
Harvey, A. (Chief Investigator), Dunlop, S. (Chief Investigator), Beazley, L. (Chief Investigator), Rodger, J. (Chief Investigator), Plant, G. (Chief Investigator), Ruitenberg, M. (Chief Investigator), Grounds, M. (Chief Investigator), Shavlakadze, T. (Chief Investigator), Waddell, B. (Chief Investigator), Mark, P. (Chief Investigator), Dharmarajan, A. (Chief Investigator), Mitchell, H. (Chief Investigator), McFawn, P. (Chief Investigator), Noble, P. (Chief Investigator), Yeoh, G. (Chief Investigator), McMenamin, P. (Chief Investigator), Filgueira, L. (Chief Investigator) & Parkinson, S. (Chief Investigator)
1/01/08 → 31/12/08
Project: Research
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403915: Intrinsic Response of Airways to Cyclical Dilation and Elongation in Breathing
Mitchell, H. (Chief Investigator), McFawn, P. (Chief Investigator) & Fernandes, L. (Chief Investigator)
1/01/06 → 31/12/08
Project: Research
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Technique for Imaging Foetal Airways to Investigate the Effects of Maternal Atopy on Airway Hyperresponsiveness
Mitchell, H. (Chief Investigator) & McFawn, P. (Chief Investigator)
The University of Western Australia
1/01/06 → 31/12/06
Project: Research