• The University of Western Australia (M519), 35 Stirling Highway,

    6009 Perth

    Australia

  • 5401 Citations
  • 42 h-Index
1995 …2022
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Research Output 1995 2019

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Article
2019
3 Citations (Scopus)

ETS1 induces transforming growth factor β signaling and promotes epithelial-to-mesenchymal transition in prostate cancer cells

Australian Prostate Cancer BioResource, Jan 2019, In : Journal of Cellular Biochemistry. 120, 1, p. 848-860

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Transforming Growth Factors
Prostate
Prostatic Neoplasms
Cells

Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development

Woo, A., Patry, C-A. A., Ghamari, A., Pregernig, G., Yuan, D., Zheng, K., Piers, T., Hibbs, M., Li, J. K., Fidalgo, M., Wang, J. Y., Lee, J-H., Leedman, P., Wang, J., Fraenkel, E. & Cantor, A. B., 27 Aug 2019, In : Blood advances. 3, 16, p. 2499-2511 13 p.

Research output: Contribution to journalArticle

Open Access
Erythroid Cells
Transcription Factors
Erythropoiesis
GATA1 Transcription Factor
Hematopoietic System
2018
34 Citations (Scopus)

A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma

Kabir, T. D., Ganda, C., Brown, R. M., Beveridge, D. J., Richardson, K. L., Chaturvedi, V., Candy, P., Epis, M., Wintle, L., Kalinowski, F., Kopp, C., Stuart, L. M., Yeoh, G. C., George, J. & Leedman, P. J., 1 Jan 2018, In : Hepatology. 67, 1, p. 216-231 16 p.

Research output: Contribution to journalArticle

MicroRNAs
Hepatocellular Carcinoma
Growth
Proto-Oncogene Proteins c-akt
1-Phosphatidylinositol 4-Kinase
4 Citations (Scopus)

Initial evaluation of thyroid dysfunction - Are simultaneous TSH and fT4 tests necessary?

Schneider, C., Feller, M., Bauer, D. C., Collet, T. H., daCosta, B. R., Auer, R., Peeters, R. P., Brown, S. J., Bremner, A. P., O’Leary, P. C., Feddema, P., Leedman, P. J., Aujesky, D., Walsh, J. P. & Rodondi, N., 1 Apr 2018, In : PLoS One. 13, 4, e0196631.

Research output: Contribution to journalArticle

Open Access
Thyroid Gland
Reference Values
Testing
prediction
Function evaluation
15 Citations (Scopus)

Total RNA extraction from tissues for microRNA and target gene expression analysis: Not all kits are created equal

Brown, R. A. M., Epis, M. R., Horsham, J. L., Kabir, T. D., Richardson, K. L. & Leedman, P. J., 16 Mar 2018, In : BMC Biotechnology. 18, 1, 16.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
RNA
Gene Expression
Chloroform
Phenol
2017
8 Citations (Scopus)

miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression

Epis, M. R., Giles, K. M., Beveridge, D. J., Richardson, K. L., Candy, P. A., Stuart, L. M., Bentel, J., Cohen, R. J. & Leedman, P. J., 2017, In : Oncotarget. 8, 33, p. 55116-55134 19 p.

Research output: Contribution to journalArticle

Open Access
Aurora Kinases
MicroRNAs
Prostatic Neoplasms
Carcinogenesis
Neoplasms
2016
5 Citations (Scopus)

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer

Hoyne, G., Rudnicka, C., Sang, Q. X., Roycik, M., Howarth, S., Leedman, P., Schlaich, M., Candy, P. & Matthews, V., 2016, In : BMC Cancer. 16, 12 p., 151.

Research output: Contribution to journalArticle

Open Access
Disintegrins
Metalloproteases
Prostatic Neoplasms
Biomarkers
Prostate
32 Citations (Scopus)

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-?B

Giles, K., Brown, R. A., Ganda, C., Podgorny, M., Candy, P., Wintle, L. C., Richardson, K. L., Kalinowski, F. C., Stuart, L. M., Epis, M. R., Haass, N. K., Herlyn, M. & Leedman, P. J., 2016, In : Oncotarget. 7, 22, p. 31663-31680 18 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Melanoma
Cell Proliferation
Neoplasm Metastasis
Epidermal Growth Factor Receptor
7 Citations (Scopus)

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journalArticle

Disintegrins
Metalloproteases
Prostatic Neoplasms
Pharmacology
Neoplasms
18 Citations (Scopus)

The log TSH-free T4 relationship in a community-based cohort is nonlinear and is influenced by age, smoking and thyroid peroxidase antibody status.

Brown, S. J., Bremner, A., Hadlow, N. C., Feddema, P., Leedman, P., O'Leary, P. & Walsh, J., Nov 2016, In : Clinical Endocrinology. 85, 5, p. 789-796

Research output: Contribution to journalArticle

Open Access
Iodide Peroxidase
Smoking
Sigmoid Colon
Antibodies
Linear Models
2015

Clinical potential of microRNA-7 in cancer.

Horsham, J., Kalinowski, F., Epis, M., Ganda, C., Brown, R. & Leedman, P., 2015, In : Journal of Clinical Medicine. 4, 9, p. 1668-1687

Research output: Contribution to journalArticle

Open Access
2014
18 Citations (Scopus)

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

Hilton, H. N., Graham, J. D., Oakes, S. R., Silvestri, A., Kantimm, S., Huschtscha, L. I., Ormandy, C. J., Funder, J. W., Simpson, E. R., Kuczek, E. S., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., 2014, In : Oncotarget. 5, p. 8651-8664

Research output: Contribution to journalArticle

11 Citations (Scopus)

Breast cancer prognosis predicted by nuclear receptor-coregulator networks

Doan, T. B., Eriksson, N. A., Graham, D., Funder, J. W., Simpson, E. R., Kuczek, E. S., Clyne, C., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., Jul 2014, In : Molecular Oncology. 8, 5, p. 998-1013

Research output: Contribution to journalArticle

Open Access
Cytoplasmic and Nuclear Receptors
Breast Neoplasms
Breast
Neoplasms
Gene Expression
82 Citations (Scopus)

Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., Lahti, J., Simmonds, M. J., Husemoen, L. L. N., Freathy, R. M., Shields, B. M., Pietzner, D., Nagy, R., Broer, L., Chaker, L., Korevaar, T. I. M. & 98 othersPlia, M. G., Sala, C., Voelker, U., Richards, J. B., Sweep, F. C., Gieger, C., Corre, T., Kajantie, E., Thuesen, B., Taes, Y. E., Visser, W. E., Hattersley, A. T., Kratzsch, J., Hamilton, A., Li, W., Homuth, G., Lobina, M., Mariotti, S., Soranzo, N., Cocca, M., Nauck, M., Spielhagen, C., Ross, A., Arnold, A., van de Bunt, M., Liyanarachchi, S., Heier, M., Grabe, H. J., Masciullo, C., Galesloot, T. E., Lim, E. M., Reischl, E., Leedman, P. J., Lai, S., Delitala, A., Bremner, A. P., Philips, D. I. W., Beilby, J. P., Mulas, A., Vocale, M., Abecasis, G., Forsen, T., James, A., Widen, E., Hui, J., Prokisch, H., Rietzschel, E. E., Palotie, A., Feddema, P., Fletcher, S. J., Schramm, K., Rotter, J. I., Kluttig, A., Radke, D., Traglia, M., Surdulescu, G. L., He, H., Franklyn, J. A., Tiller, D., Vaidya, B., de Meyer, T., Jorgensen, T., Eriksson, J. G., O'Leary, P. C., Wichmann, E., Hermus, A. R., Psaty, B. M., Ittermann, T., Hofman, A., Bosi, E., Schlessinger, D., Wallaschofski, H., Pirastu, N., Aulchenko, Y. S., de la Chapelle, A., Netea-Maier, R. T., Gough, S. C. L., Meyer zu Schwabedissen, H., Frayling, T. M., Kaufman, J-M., Linneberg, A., Raeikkoenen, K., Smit, J. W. A., Kiemeney, L. A., Rivadeneira, F., Uitterlinden, A. G., Walsh, J. P., Meisinger, C., Den Heijer, M., Visser, T. J., Spector, T. D., Wilson, S. G., Voelzke, H., Cappola, A., Toniolo, D., Sanna, S., Naitza, S. & Peeters, R. P., Feb 2014, In : PLoS Genetics. 10, 2, p. 1-13 13 p., e1004123.

Research output: Contribution to journalArticle

Open Access
65 Citations (Scopus)

microRNA-7: a tumor suppressor miRNA with therapeutic potential

Kalinowski, F., Brown, R., Ganda, C., Giles, K. M., Epis, M., Horsham, J. & Leedman, P., Sep 2014, In : International Journal of Biochemistry and Cell Biology. 54, p. 312-317

Research output: Contribution to journalArticle

MicroRNAs
Tumors
Neoplasms
Untranslated RNA
Physiology
40 Citations (Scopus)

miR-331-3p regulates expression of neuropilin-2 in glioblastoma

Epis, M., Giles, K., Candy, P., Webster, R. & Leedman, P., Jan 2014, In : Journal of Neuro-Oncology. 116, 1, p. 67-75

Research output: Contribution to journalArticle

Open Access
Neuropilin-2
Glioblastoma
Cell Line
Growth
MicroRNAs
19 Citations (Scopus)

PRMT2 and RORy Expression Are Associated With Breast Cancer Survival Outcomes

Oh, T. G., Bailey, P., Dray, E., Smith, A. G., Goode, J., Eriksson, N., Funder, J. W., Fuller, P. J., Simpson, E. R., Tilley, W. D., Leedman, P., Clarke, C. L., Grimmond, S., Dowhan, D. H. & Muscat, G. E. O., 2014, In : Molecular Endocrinology. 28, p. 1166-1185

Research output: Contribution to journalArticle

2013
88 Citations (Scopus)
401 Downloads (Pure)

Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib

Giles, K., Kalinowski, F., Candy, P., Epis, M., Zhang, P., Redfern, A., Stuart, L., Goodal, G. J. & Leedman, P., Nov 2013, In : Molecular Cancer Therapeutics. 12, 11, p. 2541-2558

Research output: Contribution to journalArticle

Open Access
File
Head and Neck Neoplasms
Epidermal Growth Factor Receptor
MicroRNAs
Phenotype
Neoplasms
25 Citations (Scopus)

Distinct nuclear receptor expression in stroma adjacent to breast tumors

Knower, K. C., Chand, A. L., Eriksson, N., Takagi, K., Miki, Y., Sasano, H., Visvader, J. E., Lindeman, G. J., Funder, J. W., Fuller, P. J., Simpson, E. R., Tilley, W. D., Leedman, P., Graham, J. D., Muscat, G. E. O., Clarke, C. L. & Clyne, C. D., Nov 2013, In : Breast Cancer Research and Treatment. 142, 1, p. 211-223 13 p.

Research output: Contribution to journalArticle

Cytoplasmic and Nuclear Receptors
Breast Neoplasms
Estrogen Receptors
Fibroblasts
Thyroid Hormone Receptors
11 Citations (Scopus)

Loss of the Nuclear Receptor Corepressor SLIRP Compromises Male Fertility

Colley, S., Wintle, L., Searles, R., Russell, V., Firman, R., Smith, S., Deboer, K., Merriner, D. J., Genevieve, B., Bentel, J., Stuckey, B., Phillips, M. R., Simmons, L., De Kretser, D. M., O'Bryan, M. K. & Leedman, P., 2013, In : PLoS One. 8, 8, p. 8pp

Research output: Contribution to journalArticle

Open Access
32 Citations (Scopus)

Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients

Candy, P. A., Phillips, M., Redfern, A., Colley, S., Davidson, A., Stuart, L., Wood, B. A., Zeps, N. & Leedman, P., 2013, In : British Journal of Cancer. 109, 4, p. 1023-1030

Research output: Contribution to journalArticle

Open Access
Fluorouracil
Colorectal Neoplasms
Transcription Factors
Survival
Mucous Membrane
49 Citations (Scopus)
385 Downloads (Pure)

Research resource: Nuclear receptors as transcriptome: Discriminant and prognostic value in breast cancer

Muscat, G. E. O., Eriksson, N. A., Byth, K., Loi, S., Graham, D., Jindal, S., Davis, M. J., Clyne, C., Funder, J. W., Simpson, E. R., Ragan, M. A., Kuczek, E., Fuller, P. J., Tilley, W. D., Leedman, P. & Clarke, C. L., 2013, In : Molecular Endocrinology. 27, p. 350-365

Research output: Contribution to journalArticle

Open Access
File
56 Citations (Scopus)

RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators

Redfern, A., Colley, S., Beveridge, D., Ikeda, N., Epis, M., Li, X., Foulds, C. E., Stuart, L., Barker, A., Russell, V., Ramsay, K., Kobelke, S., Hatchell, E., Payne, C. J., Giles, K., Messineo, A., Gatignol, A., Lanz, R. B., O'Malley, B. W. & Leedman, P., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. 6536-6541

Research output: Contribution to journalArticle

RNA-Induced Silencing Complex
RNA-Binding Proteins
Cytoplasmic and Nuclear Receptors
MicroRNAs
Transcriptional Activation
2012
11 Citations (Scopus)
166 Downloads (Pure)

ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-alpha

Jowett, J. B. M., Okada, Y., Leedman, P., Curran, J. E., Johnson, M. P., Moses, E., Goring, H. H. H., Mochizuki, S., Blangero, J., Stone, L., Allen, H., Mitchell, C. & Matthews, V., 25 Sep 2012, In : Immunology and Cell Biology. 90, 10, p. 966-973

Research output: Contribution to journalArticle

Open Access
File
Metalloproteases
Tumor Necrosis Factor-alpha
Small Interfering RNA
Macrophages
Pharmacology
147 Citations (Scopus)

Age-Related Changes in Thyroid Function: A Longitudinal Study of a Community-Based Cohort

Bremner, A., Feddema, P., Leedman, P., Brown, S. J., Beilby, J., Lim, E., Wilson, S., O'Leary, P. & Walsh, J., 2012, In : Journal of Clinical Endocrinology & Metabolism. 97, 5, p. 1554-1562

Research output: Contribution to journalArticle

Longitudinal Studies
Thyroid Gland
Aging of materials
Iodide Peroxidase
Antibodies
23 Citations (Scopus)

Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides

Yoga, Y. M. K., Traore, D. A. K., Sidiqi, M., Szeto, C., Pendini, N. R., Barker, A., Leedman, P., Wilce, J. A. & Wilce, M. C. J., 2012, In : Nucleic Acids Research. 40, p. 5101-5114

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

Matrigel Basement Membrane Matrix influences expression of microRNAs in cancer cell lines

Price, K., Tsykin, A., Giles, K., Sladic, R. T., Epis, M., Ganss, R., Goodall, G. J. & Leedman, P., 2012, In : Biochemical and Biophysical Research Communications. 427, p. 343-348

Research output: Contribution to journalArticle

60 Citations (Scopus)

miRNA-7-5p inhibits melanoma cell migration and invasion

Giles, K., Brown, R., Epis, M., Kalinowski, F. & Leedman, P., 2012, In : Biochemical and Biophysical Research Communications. 430, p. 706-710

Research output: Contribution to journalArticle

42 Citations (Scopus)

Nuclear Pore Component Nup98 Is a Potential Tumor Suppressor and Regulates Posttranscriptional Expression of Select p53 Target Genes

Singer, S., Zhao, R., Barsotti, A. M., Ouwehand, A., Fazollahi, M., Coutavas, E., Breuhahn, K., Neumann, O., Longerich, T., Pusterla, T., Powers, M. A., Giles, K., Leedman, P., Hess, J., Grunwald, D., Bussemaker, H. J., Singer, R. H., Schirmacher, P. & Prives, C., 2012, In : Molecular Cell. 48, p. 799-810

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Protein arginine methyltransferase 6-dependent gene expression and splicing: association with breast cancer outcomes

Dowhan, D. H., Harrison, M. J., Eriksson, N. A., Bailey, P., Pearen, M. A., Fuller, P. J., Funder, J. W., Simpson, E. R., Leedman, P., Tilley, W. D., Brown, M. A., Clarke, C. L. & Muscat, G. E. O., 2012, In : Endocrine-Related Cancer. 19, p. 509-526

Research output: Contribution to journalArticle

48 Citations (Scopus)

Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7

Kalinowski, F., Giles, K., Candy, P. A., Ali, A., Ganda, C., Epis, M., Webster, R. & Leedman, P., 24 Oct 2012, In : PLoS One. 7, p. 1-16

Research output: Contribution to journalArticle

Open Access
Head and Neck Neoplasms
MicroRNAs
microRNA
Epidermal Growth Factor Receptor
neck
32 Citations (Scopus)

Regulation of Expression of Deoxyhypusine Hydroxylase (DOHH), the Enzyme That Catalyzes the Activation of elF5A, by miR-331-3p and miR-642-5p in Prostate Cancer Cells

Epis, M., Giles, K., Kalinowski, F., Barker, A., Cohen, R. & Leedman, P., Oct 2012, In : Journal of Biological Chemistry. 287, p. 35251-35259

Research output: Contribution to journalArticle

Open Access
deoxyhypusine hydroxylase
Prostatic Neoplasms
Chemical activation
Cells
Enzymes
38 Citations (Scopus)

Sequence requirements for RNA binding by HuR and AUF1

Barker, A., Epis, M., Porter, C. J., Hopkins, B. R., Wilce, M. C. J., Giles, K. & Leedman, P., 2012, In : Journal of Biochemistry. 151, p. 423-437

Research output: Contribution to journalArticle

29 Citations (Scopus)

Significant association between thyroid hormones and erythrocyte indices in euthyroid subjects

Bremner, A., Feddema, P., Joske, D., Leedman, P., O'Leary, P., Olynyk, J. & Walsh, J., 2012, In : Clinical Endocrinology. 76, p. 304-311

Research output: Contribution to journalArticle

2011
26 Citations (Scopus)

A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement

Taylor, P. N., Panicker, V., Sayers, A., Shields, B., Iqbal, A., Bremner, A., Beilby, J., Leedman, P., Hattersley, A. T., Vaidya, B., Frayling, T., Evans, J., Timpson, N. J., Tobias, J. H., Walsh, J. & Dayan, C. M., 2011, In : European Journal of Endocrinology. 164, p. 773-780

Research output: Contribution to journalArticle

91 Citations (Scopus)

miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion

Thomson, D., Giles, K., Maleki, S., Mreich, E., Wheeler, H., Leedman, P., Biggs, M., Cook, R., Little, N., Robinson, B., Mcdonald, K. & Fowler, A., 2011, In : European Journal of Cancer. 47, 6, p. 953-963

Research output: Contribution to journalArticle

58 Citations (Scopus)

The RNA-binding Protein HuR Opposes the Repression of ERBB-2 Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells

Epis, M., Barker, A. P., Giles, K., Beveridge, D. & Leedman, P., 2011, In : The Journal of Biological Chemistry. 286, 48, p. 41442-41454

Research output: Contribution to journalArticle

2010
25 Citations (Scopus)

Post-transcriptional regulation of androgen receptor mRNA by an ErbB3 binding protein 1 in prostate cancer

Zhou, H., Mazan-Mamczarz, K., Martindale, J. L., Barker, A., Liu, Z., Gorospe, M., Leedman, P., Gartenhaus, R. B., Hamburger, A. W. & Zhang, Y., 2010, In : Nucleic Acids Research. 38, 11, p. 3619-3631

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Regulation of ErbB receptor signalling in cancer cells by microRNA

Barker, A., Giles, K., Epis, M., Zhang, P., Kalinowski, F. & Leedman, P., 2010, In : Current Opinion in Pharmacology. 10, p. 655-661

Research output: Contribution to journalArticle

57 Citations (Scopus)

The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs

Athanasopoulos, V., Barker, A., Yu, D., Tan, A. H. M., Srivastava, M., Contreras, N., Wang, J. B., Lam, K. P., Brown, S. H. J., Goodnow, C. C., Dixon, N. E., Leedman, P., Saint, R. & Vinuesa, C. G., 2010, In : FEBS Journal. 227, p. 2109-2127

Research output: Contribution to journalArticle

2009
19 Citations (Scopus)

Downstream Targets of Heterogeneous Nuclear Ribonucleoprotein A2 Mediate Cell Proliferation

He, Y., Rothnagel, J. A., Epis, M., Leedman, P. & Smith, R., 2009, In : Molecular Carcinogenesis. 48, 2, p. 167-179

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein Group A-B
Heterogeneous-Nuclear Ribonucleoproteins
varespladib methyl
Cell Proliferation
Proto-Oncogenes
24 Citations (Scopus)

Interferon-induced thyroid dysfunction in chronic hepatitis C

Jamil, K. M., Leedman, P., Kontorinis, N., Tarquinio, L., Nazareth, S., Mcinerney, M., Connelly, C., Flexman, J., Burke, V., Metcalf, C. & Cheng, W., 2009, In : Journal of Gastroenterology and Hepatology. 24, 6, p. 1017-23

Research output: Contribution to journalArticle

Chronic Hepatitis C
Interferons
Thyroid Gland
Interferon-alpha
Iodide Peroxidase
111 Citations (Scopus)

miR-331-3p Regulates ERBB-2 Expression and Androgen Receptor Signaling in Prostate Cancer

Epis, M., Giles, K., Barker, A., Kendrick, T. S. & Leedman, P., 2009, In : The Journal of Biological Chemistry. 284, 37, p. 24696-24704

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Cells
Prostate-Specific Antigen
Phosphatidylinositol 3-Kinase
330 Citations (Scopus)

Regulation of Epidermal Growtrh Factor Receptor Signaling in Human Cancer Cells by MicroRNA-7

Webster, R., Giles, K., Price, K., Zhang, P., Mattick, J. S. & Leedman, P., 2009, In : The Journal of Biological Chemistry. 284, 9, p. 5731-41

Research output: Contribution to journalArticle

MicroRNAs
Epidermal Growth Factor Receptor
Cells
Neoplasms
Messenger RNA
33 Citations (Scopus)
Cytoplasmic and Nuclear Receptors
Gene expression
Nuclear Receptor Coactivators
RNA
Transcription
42 Citations (Scopus)

The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cells

Herbison, C. E., Thorstensen, K., Chua, A., Graham, R., Leedman, P., Olynyk, J. & Trinder, D., 2009, In : American journal of physiology : cell physiology. 297, 6, p. C1567-C1575

Research output: Contribution to journalArticle

Transferrin Receptors
Transferrin
Hepatocellular Carcinoma
Iron
Coordination Complexes
2008
35 Citations (Scopus)

Erythroid defects in TRa -/- mice

Kendrick, T. S., Payne, C. J., Epis, M. R., Schneider, J. R., Leedman, P., Klinken, P. & Ingley, E., 2008, In : Blood. 111, 6, p. 3245-48

Research output: Contribution to journalArticle

Erythropoiesis
Defects
Hemolytic Anemia
Thyroid Hormones
Liver
75 Citations (Scopus)

Iron and the Translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease

Rogers, J. T., Bush, A. I., Cho, H-H., Smith, D. H., Thomson, A. M., Friedlich, A. L., Lahiri, D. K., Leedman, P., Huang, X. & Cahill, C. M., 2008, In : Biochemical Society Transactions. 36, 6, p. 1282-1287

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Ferritins
Alzheimer Disease
Iron
Messenger RNA
35 Citations (Scopus)

Posttranscriptional Regulation of the Breast Cancer Susceptibility Gene BRCA1 by the RNA Binding Protein HuR

Saunus, J. M., French, J. D., Edwards, S. L., Beveridge, D. J., Hatchell, E. C., Wagner, S. A., Stein, S. R., Simpson, K. J., Francis, G. D., Leedman, P., Brown, M. A. & Davidson, A., 2008, In : Cancer Research. 68, 22, p. 9469-78

Research output: Contribution to journalArticle

RNA-Binding Proteins
Neoplasm Genes
3' Untranslated Regions
Breast Neoplasms
BRCA1 Protein