Paul Rigby

Associate Professor, BSc PhD W.Aust.

  • The University of Western Australia (M010), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1779 Citations
  • 21 h-Index
1990 …2019
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Research Output 1990 2019

2019

Complementary Approaches to Imaging Subcellular Lipid Architectures in Live Bacteria Using Phosphorescent Iridium Complexes and Raman Spectroscopy

Ranieri, A. M., Caporale, C., Fiorini, V., Hubbard, A., Rigby, P., Stagni, S., Watkin, E., Ogden, M. I., Hackett, M. J. & Massi, M., Jul 2019, In : CHEMISTRY-A EUROPEAN JOURNAL. 6 p.

Research output: Contribution to journalLetter

2018
11 Citations (Scopus)

Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma

Looi, K., Buckley, A. G., Rigby, P. J., Garratt, L. W., Iosifidis, T., Zosky, G. R., Larcombe, A. N., Lannigan, F. J., Ling, K. M., Martinovich, K. M., Kicic-Starcevich, E., Shaw, N. C., Sutanto, E. N., Knight, D. A., Kicic, A. & Stick, S. M., 1 May 2018, In : Clinical and Experimental Allergy. 48, 5, p. 513-524 12 p.

Research output: Contribution to journalArticle

Rhinovirus
Tight Junctions
Asthma
Claudin-1
Occludin
1 Citation (Scopus)
Open Access
Trypanosoma
Marsupialia
Trypanosomiasis
Parasites
Trypanosoma cruzi
4 Citations (Scopus)

Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

Buckley, A. G., Looi, K., Iosifidis, T., Ling, K. M., Sutanto, E. N., Martinovich, K. M., Kicic-Starcevich, E., Garratt, L. W., Shaw, N. C., Lannigan, F. J., Larcombe, A. N., Zosky, G., Knight, D. A., Rigby, P. J., Kicic, A. & Stick, S. M., 1 Feb 2018, In : Biological Procedures Online. 20, 1, 3.

Research output: Contribution to journalArticle

Open Access
Methanol
Visualization
Epithelial Cells
Staining and Labeling
Acetone
2017

IDENTIFYING A NOVEL THERAPEUTIC STRATEGY FOR ASTHMA: TARGETING AIRWAY EPITHELIAL CELL RESTITUTION

Iosifidis, T., Gill, E. E., Buckley, A. G., Sutanto, E. N., Ling, K. M., Garratt, L. W., Looi, K., Kicic-Starcevich, E., Martinovich, K. M., Shaw, N. C., Montgomery, T., Lannigan, F. J., Rigby, P. J., Hancock, R. E. W., Knight, A., Stick, S. M., Kicic, A., WAERP & Lee, A. H., Nov 2017, In : Respirology. 22, p. 81-81 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2016
16 Citations (Scopus)
Open Access
Blood-Brain Barrier
Nanoparticles
Optic Nerve Injuries
Cerebrovascular Disorders
Brain
6 Citations (Scopus)
198 Downloads (Pure)

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability

Looi, K., Troy, N. M., Garratt, L. W., Iosifidis, T., Bosco, A., Buckley, A. G., Ling, K-M. M., Martinovich, K. M., Kicic-Starcevich, L., Shaw, N. C., Sutanto, E. N., Zosky, G. R., Rigby, P. J., Larcombe, A. N., Knight, D. A., Kicic, A. & Stick, S. M., 11 Oct 2016, In : Experimental Lung Research. 42, 7, p. 380-395 16 p.

Research output: Contribution to journalArticle

Open Access
File
Tight Junction Proteins
Rhinovirus
Polymerase chain reaction
Zonula Occludens-1 Protein
Claudin-1
22 Citations (Scopus)
214 Downloads (Pure)

Impaired airway epithelial cell responses from children with asthma to rhinoviral infection

Kicic, A., Stevens, P. T., Sutanto, E. N., Kicic-Starcevich, E., Ling, K-M., Looi, K., Martinovich, K. M., Garratt, L. W., Iosifidis, T., Shaw, N. C., Buckley, A. G., Rigby, P. J., Lannigan, F. J., Knight, D. A. & Stick, S. M., Nov 2016, In : Clinical and Experimental Allergy. 46, 11, p. 1441-1455

Research output: Contribution to journalArticle

Open Access
File
Asthma
Epithelial Cells
Rhinovirus
Infection
Virus Receptors
6 Citations (Scopus)

Large-scale reconstitution of a retina-to-brain pathway in adult rats using gene therapy and bridging grafts: An anatomical and behavioral analysis

You, S. W., Hellström, M., Pollett, M., Levaillant, C., Moses, C., Rigby, P., Penrose, M., Rodger, J. & Harvey, A., May 2016, In : Experimental Neurology. 279, p. 197-211

Research output: Contribution to journalArticle

Dependovirus
Superior Colliculi
Ciliary Neurotrophic Factor
Genetic Therapy
Retina
2015
10 Citations (Scopus)

Rhenium tetrazolato complexes coordinated to thioalkyl-functionalised phenanthroline ligands: Synthesis, photophysical characterisation, and incubation in live HeLa cells

Werrett, M. V., Wright, P. J., Simpson, P. V., Raiteri, P., Skelton, B., Stagni, S., Buckley, A., Rigby, P. & Massi, M., 21 Dec 2015, In : Dalton Transactions. 44, 47, p. 20636-20647 12 p.

Research output: Contribution to journalArticle

Rhenium
Phenanthrolines
Ligands
Charge transfer
Photobleaching
2014
8 Citations (Scopus)

Flow cytometry as a rapid and reliable method to quantify sperm viability in the honeybee Apis mellifera

Paynter, E., Baer-Imhoof, B., Linden, M., Lee-Pullen, T., Heel, K., Rigby, P. & Baer, B., May 2014, In : Cytometry Part A. 85, 5, p. 463-472

Research output: Contribution to journalArticle

Open Access
Bees
Spermatozoa
Flow Cytometry
Fluorescence Microscopy
Coloring Agents
14 Citations (Scopus)

Megafaunal split ends: Microscopical characterisation of hair structure and function in extinct woolly mammoth and woolly rhino

Tridico, S. R., Rigby, P., Kirkbride, K. P., Haile, J. & Bunce, M. A., Jan 2014, In : Quaternary Science Reviews. 83, p. 68-75 8 p.

Research output: Contribution to journalArticle

hair
hairs
examination
Arctic
damages
2013
47 Citations (Scopus)

Image analysis of liver collagen using sirius red is more accurate and correlates better with serum fibrosis markers than trichrome

Huang, Y., De Boer, W. B., Adams, L., Macquillan, G., Rossi, E., Rigby, P., Raftopoulos, S. C., Bulsara, M. & Jeffrey, G., 2013, In : Liver International. 33, 8, p. 1249-1256

Research output: Contribution to journalArticle

16 Citations (Scopus)

Preliminary studies on the development of IgA-loaded chitosan-dextran sulphate nanoparticles as a potential nasal delivery system for protein antigens

Sharma, S., Benson, H. A. E., Mukkur, T. K. S., Rigby, P. & Chen, Y., 2013, In : Journal of Microencapsulation. 30, 3, p. 283-294

Research output: Contribution to journalArticle

19 Citations (Scopus)

Quantitative Förster resonance energy transfer efficiency measurements using simultaneous spectral unmixing of excitation and emission spectra

Mustafa, S., Hannagan, J., Rigby, P., Pfleger, K. & Corry, B., 2013, In : Journal of Biomedical Optics. 18, 2, p. 026024-1 - 026024-14

Research output: Contribution to journalArticle

Open Access
2012
18 Citations (Scopus)

Comparison of noninvasive models of fibrosis in chronic hepatitis B

Raftopoulos, S. C., George, J., Bourliere, M., Rossi, E., De Boer, W. B., Jeffrey, G., Bulsara, M., Speers, D. J., Macquillan, G., Ching, H. L. I., Kontorinis, N., Cheng, W., Flexman, J., Fermoyle, S., Rigby, P., Walsh, L., Mcleod, D. & Adams, L., 2012, In : Hepatology International. 6, p. 457–467

Research output: Contribution to journalArticle

17 Citations (Scopus)
2011
66 Citations (Scopus)

Multi-species Bacterial Biofilm and Intracellular Infection in Otitis Media

Thornton, R., Rigby, P., Wiertsema, S., Filion, P., Langlands, J., Coates, H., Vijayasekaran, S., Keil, A. D. & Richmond, P., 2011, In : BMC Pediatrics. 11, 94, p. 1-10

Research output: Contribution to journalArticle

Open Access
2010
59 Citations (Scopus)

An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation

Corry, B., Hurst, A. C., Pal, P., Nomura, T., Rigby, P. & Martinac, B., 2010, In : Journal of General Physiology. 136, 4, p. 483-494

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)

Fibrin phantom for use in optical coherence tomography

Kennedy, B., Loitsch, S., Mclaughlin, R., Scolaro, L., Rigby, P. & Sampson, D., 2010, In : Journal of Biomedical Optics. 15, 3, p. 030507-1 to 030507-3

Research output: Contribution to journalArticle

80 Citations (Scopus)

Fossil avian eggshell preserves ancient DNA

Oskam, C. L., Haile, J., Mclay, E., Rigby, P., Allentoft, M. E., Olsen, M. E., Bengtsson, C., Miller, G. H., Schwenninger, J. L., Jacomb, C., Walter, R., Baynes, A., Dortch, J., Parker-Pearson, M., Gilbert, M. T. P., Holdaway, R. N., Willerslev, E. & Bunce, M., 2010, In : Royal Society of London. Proceedings B. Biological Sciences. 277, p. 1991-2000

Research output: Contribution to journalArticle

Open Access
2009
6 Citations (Scopus)

Cells of epithelial lineage are present in blood, engraft the bronchial epithelium, and are increased in human lung transplantation

May, L. A., Kicic, A., Rigby, P., Heel, K., Pullen, T., Crook, M., Charles, A., Banerjee, B., Ravine, D., Saxena, A., Musk, M., Stick, S., Chambers, D. & Kicic, A., 2009, In : Journal of Heart and Lung Transplantation. 28, 6, p. 550-557

Research output: Contribution to journalArticle

Lung Transplantation
Cell Lineage
Epithelium
Fluorescence In Situ Hybridization
Microsatellite Repeats
2008
18 Citations (Scopus)

Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma

Singh, J., Naran, A., Misso, N., Rigby, P., Thompson, P. & Bhoola, K., 2008, In : International Immunopharmacology. 8, p. 300-306

Research output: Contribution to journalArticle

Kallikreins
Peptide Hydrolases
Carcinoma
Lung
Lung Neoplasms
19 Citations (Scopus)
328 Citations (Scopus)

Vascular normalization in Rgs5-deficient tumours promotes immune destruction

Hamzah, J., Jugold, M., Kiessling, F., Rigby, P., Manzur, M., Marti, H. H., Rabie, T., Kaden, S., Grone, H-J., Hammerling, G. J., Bernd, A. & Ganss, R., 2008, In : Nature. 453, 15, p. 410-414

Research output: Contribution to journalArticle

Tumors
Proteins
Bearings (structural)
Genes
Demonstrations
2007
25 Citations (Scopus)

Reliability of Confocal Microscopy Spectral Imaging Systems: Use of Multispectral Beads.

Zucker, R. M., Rigby, P., Clements, I., Salmon, W. & Chua, M., 2007, In : Cytometry Part A. 71, 3, p. 174-189

Research output: Contribution to journalArticle

2006
40 Citations (Scopus)

Antigen from the Anterior Chamber of the Eye Travels in a Soluble Form to Secondary Lymphoid Organs via Lymphatic and Vascular Routes

Camelo, S., Kezic, J., Shanley, A., Rigby, P. & Mcmenamin, P., 2006, In : Investigative ophthalmology & visual science. 47, 3, p. 1039-1046

Research output: Contribution to journalArticle

Anterior Chamber
Blood Vessels
Antigens
Injections
Fluorescein-5-isothiocyanate
34 Citations (Scopus)
Physical Chemistry
Transfer Factor
Liposomes
Biochemistry
Spectrum Analysis
2005
61 Citations (Scopus)
Energy Transfer
Lasers
Proteins
52 Citations (Scopus)

Conformational Changes Involved in MscL Channel Gating Measured using FRET Spectroscopy

Corry, B., Rigby, P., Liu, Z-W. & Martinac, B., 2005, In : Biophysical Journal. 89, 6, p. L49 - L51

Research output: Contribution to journalArticle

Ion Channel Gating
Photobleaching
Fluorescence Resonance Energy Transfer
Liposomes
Cysteine
18 Citations (Scopus)

Visualisation of the mechanosensitive channel of large conductance in bacteria using confocal microscopy

Norman, C., Liu, Z-W., Rigby, P., Raso, A., Petrov, Y. & Martinac, B., 2005, In : European Biophysics Journal. 34, 5, p. 396-402

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Confocal Microscopy
Bacteria
Gene Fusion
Osmotic Pressure
2004
17 Citations (Scopus)
Phosphoenolpyruvate
Kupffer Cells
Gluconeogenesis
Interleukin-1
Interleukin-10
2003
76 Citations (Scopus)

Macrophage recognition and phagocytosis of apoptotic fibroblasts is critically dependent on fibroblast-derived thrombospondin 1 and CD36

Moodley, Y., Rigby, P., Bundell, C., Bunt, S., Hayashi, H., Misso, N., Mcanulty, R., Laurent, G., Scaffidi, A., Thompson, P. & Knight, D., 2003, In : American Journal of Pathology. 162, 3, p. 177-179

Research output: Contribution to journalArticle

Thrombospondin 1
Phagocytosis
Fibroblasts
Macrophages
Phagocytes
2002
2 Citations (Scopus)

Airway nerves: detection and visualisation

Goldie, R., Fernandes, L. & Rigby, P., 2002, In : Current Opinion in Pharmacology. 2, 3, p. 273-277

Research output: Contribution to journalArticle

Nerve Tissue
Disease Management
Confocal Microscopy
Chronic Obstructive Pulmonary Disease
Fluorescent Antibody Technique
2 Citations (Scopus)

Impact of parainfluenza-3 virus infection on endothelin receptor density and function in guinea pig airways

D'Aprile, A. C., Fernandes, L., Rigby, P. & Goldie, R., 2002, In : Clinical Science. 103, 48, p. 345S-348S

Research output: Contribution to journalArticle

Paramyxoviridae Infections
Endothelin Receptors
Guinea Pigs
Binding Sites
Endothelin-1
2001
7 Citations (Scopus)

Differential modulation of endothelin ligand-induced contraction in isolated tracheae from endothelin B (ETB) receptor knockout mice

Hay, D. W. P., Douglas, S. A., Zhao, A., Ohlstein, E. A., Moesker, R. M., Self, G. J., Rigby, P., Luttman, M. A. & Goldie, R., 2001, In : British Journal of Pharmacology. 132, p. 1905-1915

Research output: Contribution to journalArticle

Endothelin B Receptors
Endothelins
Trachea
Knockout Mice
Ligands
4 Citations (Scopus)

The Impact of Inflammation on Bronchial Neuronal Networks

Goldie, R., Rigby, P., Fernandes, L. & Henry, P., 2001, In : Pulmonary Pharmacology and Therapeutics. 14, p. 177-182

Research output: Contribution to journalReview article

Inflammation Mediators
Neuronal Plasticity
Inflammation
Phenotype
Plasticity
2000
2 Citations (Scopus)

Ageing and epithelial integrity as modulators of airway smooth muscle responsiveness to endothelin-1

Preuss, J. M. H., Rigby, P. & Goldie, R., 2000, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 361, p. 391-396

Research output: Contribution to journalArticle

Endothelin-1
Smooth Muscle
Inositol Phosphates
Guinea Pigs
Epithelium
10 Citations (Scopus)

Influence of endothelin-1((1-31)) on smooth muscle tone and cholinergic nerve-mediated contraction in rat isolated trachea

Goldie, R., D'Aprile, A. C., Self, G. J., Rigby, P. & Henry, P., 2000, Endothelin VI. Luscher, T. F. (ed.). Montreal, Canada ed. Philidelphia, USA: Lippincott Williams & Wilkins, Vol. 36. p. S228-S231

Research output: Chapter in Book/Conference paperConference paper

Trachea
Cholinergic Agents
Smooth Muscle
Asthma
Lung
85 Citations (Scopus)

Interaction between Burkholderia pseudomallei and Acanthamoeba Species Results in Coiling Phagocytosis, Endamebic Bacterial Survival, and Escape

Inglis, T. J. J., Inglis, T. J. J., Rigby, P., Rigby, P., Robertson, T. A., Dutton, N., Henderson, M., Chang, B. & Chang, B. J., 2000, In : Infection and Immunity. 68, 3, p. 1681-1686

Research output: Contribution to journalArticle

Burkholderia pseudomallei
Acanthamoeba
Phagocytosis
Coculture Techniques
Survival
1999
6 Citations (Scopus)

Confocal Microscopy in Biomedical Research

Rigby, P. & Goldie, R., 1999, In : Croatian Medical Journal. 40, (3), p. 346-352

Research output: Contribution to journalArticle

Confocal Microscopy
Biomedical Research
Optical Imaging
Ultraviolet Microscopy
Technology
12 Citations (Scopus)

The influence of animal age on beta-adrenoceptor density and function in tracheal airway smooth muscle

Preuss, J. M. H., Rigby, P. & Goldie, R., 1999, In : Naunyn-Schmiedebergs Archives of Pharmacology. 360, p. 171-178

Research output: Contribution to journalArticle

Adrenergic Receptors
Smooth Muscle
Guinea Pigs
Guaiacol
Transferases
1998
4 Citations (Scopus)

Age and region-dependent contraction to alpha-adrenoceptor agonists in rat and guinea-pig isolated trachea

Preuss, J. M. H., Rigby, P. & Goldie, R., 1998, In : British Journal of Pharmacology. 123, p. 1541-1548

Research output: Contribution to journalArticle

Trachea
Adrenergic Receptors
Epinephrine
Guinea Pigs
Norepinephrine
4 Citations (Scopus)

Airway structure in asthma: A role for confocal microscopy?

Goldie, RG., Fernandes, LB., Rigby, P., Pudney, CJ., Spalding, LJ., O'Connor, BJ. & Page, CP., 1998, In : Pulmonary Pharmacology and Therapeutics. 11, p. 349-354

Research output: Contribution to journalArticle

Autoradiography in the Lung

Goldie, R. & Rigby, P., 1998, Methods in Pulmonary Research. Uhlig, S. & Taylor, A. E. (eds.). Basel, Switzerland: Birkhauser Verlag, Vol. not applicable. p. 455-481

Research output: Chapter in Book/Conference paperChapter

4 Citations (Scopus)
Endothelin-1
Virus Diseases
Respiratory Tract Infections
Cholinergic Agents
Electric Stimulation
1 Citation (Scopus)
Histamine
Smooth Muscle
Guinea Pigs
Acetylcholine
Signal Transduction