Patrick Holt

The University of Western Australia (M560), 35 Stirling Highway,
6009 Perth
Australia

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Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

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Dive into the research topics where Patrick Holt is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

1 Similar Profiles

Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trial
Chacón, G. P., Estcourt, M. J., Totterdell, J., Marsh, J. A., Perrett, K. P., Campbell, D. E., Wood, N., Gold, M., Waddington, C. S., Sullivan, M. O., McAlister, S., Curtis, N., Jones, M., McIntyre, P. B., Holt, P. G., Richmond, P. C. & Snelling, T., 10 Jun 2024, (Accepted/In press) In: PLoS Medicine. 21, 6 , e1004414.
Research output: Contribution to journal › Article › peer-review

Open Access
Impaired interferon response in plasmacytoid dendritic cells from children with persistent wheeze
Coenen, I., de Jong, E., Jones, A. C., Khoo, S. K., Foo, S., Howland, S. W., Ginhoux, F., Le Souëf, P. N., Holt, P. G., Strickland, D. H., Laing, I. A. & Leffler, J., Apr 2024, In: Journal of Allergy and Clinical Immunology. 153, 4, p. 1083-1094 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Budu-Aggrey, A., Kilanowski, A., Sobczyk, M. K., Shringarpure, S. S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B. M., Thomas, L. F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J. V. T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A., & 112 othersJeong, A., Fawcett, K. A., Baurecht, H., Rodriguez, E., Alves, A. C., Kumar, A., Sleiman, P. M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C. J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C. A., Thiering, E., Wu, B., Kress, S., Kothalawala, D. M., Kadalayil, L., Duan, J., Zhang, H., Hadebe, S., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O. A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P. K. E., Szwajda, A., Burchard, E. G., Thyssen, J. P., Hansen, T., Kårhus, L. L., Dantoft, T. M., Jeanrenaud, A. C. S. N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M. M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D. I., Hottenga, J. J., Müller-Nurasyid, M., Ahluwalia, T. S., Stokholm, J., Chawes, B., Schoos, A. M. M., Esplugues, A., Bustamante, M., Raby, B., Arshad, S., German, C., Esko, T., Milani, L. A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D. P., Grarup, N., Linneberg, A., Lee, Y. A., Probst-Hensch, N., Weidinger, S., Jarvelin, M. R., Melén, E., Hakonarson, H., Irvine, A. D., Jarvis, D., Nijsten, T., Duijts, L., Vonk, J. M., Koppelmann, G. H., Godfrey, K. M., Barton, S. J., Feenstra, B., Pennell, C. E., Sly, P. D., Holt, P. G., Williams, L. K., Bisgaard, H., Bønnelykke, K., Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S. T., Holloway, J. W., Min, J. L., Brown, S. J., Standl, M. & Paternoster, L., Dec 2023, In: Nature Communications. 14, 1, 18 p., 6172.
Research output: Contribution to journal › Article › peer-review

Open Access
18 Citations (Scopus)
LPS binding protein and activation signatures are upregulated during asthma exacerbations in children
Jones, A. C., Leffler, J., Laing, I. A., Bizzintino, J., Khoo, S. K., LeSouef, P. N., Sly, P. D., Holt, P. G., Strickland, D. H. & Bosco, A., Dec 2023, In: Respiratory Research. 24, 1, p. 184 1 p., 184.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Citations (Scopus)
Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection
Sikder, M. A. A., Rashid, R. B., Ahmed, T., Sebina, I., Howard, D. R., Ullah, M. A., Rahman, M. M., Lynch, J. P., Curren, B., Werder, R. B., Simpson, J., Bissell, A., Morrison, M., Walpole, C., Radford, K. J., Kumar, V., Woodruff, T. M., Ying, T. H., Ali, A., Kaiko, G. E., & 6 othersUpham, J. W., Hoelzle, R. D., Cuív, P., Holt, P. G., Dennis, P. G. & Phipps, S., 9 May 2023, In: Immunity. 56, 5, p. 1098-1114.e10 28 p.
Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus)

Additional file 10 of LPS binding protein and activation signatures are upregulated during asthma exacerbations in children
Jones, A. (Creator), Leffler, J. (Creator), Laing, I. (Creator), Bizzintino, J. (Creator), Khoo, K. (Creator), LeSouëf, P. N. (Creator), Sly, P. D. (Creator), Holt, P. (Creator), Strickland, D. (Creator) & Bosco, A. (Creator), Figshare, 13 Jul 2023
DOI: 10.6084/m9.figshare.23672490, https://springernature.figshare.com/articles/dataset/Additional_file_10_of_LPS_binding_protein_and_activation_signatures_are_upregulated_during_asthma_exacerbations_in_children/23672490
Dataset
Additional file 10 of LPS binding protein and activation signatures are upregulated during asthma exacerbations in children
Jones, A. (Creator), Leffler, J. (Creator), Laing, I. (Creator), Bizzintino, J. (Creator), Khoo, K. (Creator), LeSouëf, P. N. (Creator), Sly, P. D. (Creator), Holt, P. (Creator), Strickland, D. (Creator) & Bosco, A. (Creator), Figshare, 13 Jul 2023
DOI: 10.6084/m9.figshare.23672490.v1, https://springernature.figshare.com/articles/dataset/Additional_file_10_of_LPS_binding_protein_and_activation_signatures_are_upregulated_during_asthma_exacerbations_in_children/23672490/1
Dataset

1 Curtailed
36 Finished

Towards a diagnostic test for rheumatic fever
Carapetis, J., Ralph, A., Bosco, A., Maguire, G., Holt, P., Pearson, G., Broadhurst, D., Mayo, M., Albani, S. & Moreland, N.
NHMRC National Health and Medical Research Council
1/01/18 → 30/06/24
Project: Research
Multi-centre, multi-disciplinary study using a systems biology approach to investigate immunomodulation in children with acute wheeze”
Le Souef, P., Holt, P., Currie, A., Hancock, R., Laing, I., Trengove, R., Broadhurst, D., Cookson, W. & Zhang, G.
NHMRC National Health and Medical Research Council
1/01/18 → 31/12/23
Project: Research
FutureHealth Major Research Support - LIFE-CYCLE
Huang, R., Jaddoe, V., Hall, G., Lin, A., Beilin, L., Sly, P., Holt, P. & Mori, T.
Department of Health (Western Australia)
12/04/17 → 11/04/22
Project: Research
Immune Recognition of Upper Airway Microbiota in Early Life as a Determinant of Respiratory Health in Children
Hales, B., Holt, P. & Grimwood, K.
NHMRC National Health and Medical Research Council
1/01/15 → 31/12/19
Project: Research
Waxing and waning of asthma during transition from the teens to adulthood: identification of immunophenotypic markers to predict disease trajectory and guide development of treatment strategies to prevent progression to chronicity
Holt, P., Hollams, E. & Bosco, A.
NHMRC National Health and Medical Research Council
1/01/15 → 30/04/18
Project: Research

Patrick Holt

Personal profile

Expertise related to UN Sustainable Development Goals

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trial

Impaired interferon response in plasmacytoid dendritic cells from children with persistent wheeze

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection

Additional file 10 of LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

Additional file 10 of LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

Towards a diagnostic test for rheumatic fever

Multi-centre, multi-disciplinary study using a systems biology approach to investigate immunomodulation in children with acute wheeze”

FutureHealth Major Research Support - LIFE-CYCLE

Immune Recognition of Upper Airway Microbiota in Early Life as a Determinant of Respiratory Health in Children

Waxing and waning of asthma during transition from the teens to adulthood: identification of immunophenotypic markers to predict disease trajectory and guide development of treatment strategies to prevent progression to chronicity

Patrick Holt

Personal profile

Expertise related to UN Sustainable Development Goals

Fingerprint

Collaborations and top research areas from the last five years

Research output

Datasets

Projects