Personal profile
Biography
Dr. Patricia Macchiaverni is a biologist and holds a dual degree, bachelor in Biological Sciences and one in Education. Shortly thereafter, she started her academic and scientific work in the laboratory of Human Immunology at University of São Paulo (USP), where she holds a master and a Ph.D. both in Immunology. Her dissertation was focused in human allergy and maternal and child health and was primarily addressed to characterize the transmission of antibodies directed to house dust mite through placenta and breast milk in allergic and non-allergic mothers. During her PhD, she started a strong collaboration with Dr. Valérie Verhasselt were she extended her previous work in humans to animal models in order to address mechanisms of tolerance induction through breastmilk. In 2013, Dr. Patricia Macchiaverni started to work as a research associate at the Center of Investigation in Pediatrics (CIPED) at University of Campinas, Brazil (UNICAMP). During this time, she worked in collaboration with Dr. Verhasselt and Dr. Annesi-Maesano using prospective population-based data from EDEN cohort (Study of Pre- and Early Post-Natal Determinants of The Childs Development and Health) to understand whether early exposure to mite allergens transferred through breast milk would affect child’s subsequent development of allergic sensitization and allergy. This work resulted in a publication as first author in the prestigious review Journal of Allergy and Clinical Immunology (IF 12.8). After eight years of academic career, Dr. Patricia Macchiaverni successfully transitioned in 2014 to the Pharmaceutical industry to work as medical science liaison (MSL) in immunology at Janssen Pharma and at Roche Pharma as Senior Scientific Manager in inflammation and neurology. The experience in the industry has aggregated to her career new important skills as the capacity to translate the scientific data to opinion leaders, community physicians, investigators and other healthcare providers. In October 2017 Dr. Patricia Macchiaverni joined the team of Professor Valérie Verhasselt at the University of Western Australia as research fellow level B, to extend her previous work and understand the mechanisms behind the impact of house dust mite allergens in maternal milk on infant allergic outcomes. With this project she aimed to identify and modulate the presence of some immunomodulatory components in breast milk to counteract house dust mite allergenic effect and contribute to the prevention of allergy.
Education/Academic qualification
Immunology, PhD, Universidade de São Paulo
Award Date: 7 Dec 2012
Immunology, Master, Universidade de São Paulo
Award Date: 12 Aug 2008
Biological Science, Bachelor, Pontifical Catholic University of Campinas
Award Date: 1 Dec 2005
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 4 Quality Education
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Collaborations and top research areas from the last five years
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Colostrum as a Protective Factor Against Peanut Allergy: Evidence From a Birth Cohort
Bhasin, M., Cooper, M., Macchiaverni, P., Joys, R. S., O'Sullivan, T. A., Keelan, J. A., Venter, C., Palmer, D. J., Lowe, A. J., Prescott, S. L., Silva, D. & Verhasselt, V., Feb 2026, In: Allergy: European Journal of Allergy and Clinical Immunology. 81, 2, p. 552-562 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study
Divakara, N., Dempsey, Z., Saraswati, C., Garssen, J., Silva, D., Keelan, J. A., Christophersen, C. T., Cooper, M. N., Prescott, S. L., Palmer, D. J., Verhasselt, V. & Macchiaverni, P., 2 Sept 2024, In: Pediatric Allergy and Immunology. 35, 9, 12 p., e14226.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Citations (Scopus) -
Specific IgA, But Not IgG, in Human Milk From COVID-19-infected Mothers Neutralizes SARS-CoV-2
Macchiaverni, P., Lloyd, M., Masters, L., Divakara, N., Panta, K., Imrie, A., Sánchez-García, L., Pellicer, A., Rodriguez, J. M. & Verhasselt, V., 1 Jun 2024, In: The Pediatric Infectious Disease Journal. 43, 6, p. 532-535 4 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Citations (Scopus) -
House Dust Mite Exposure through Human Milk and Dust: What Matters for Child Allergy Risk?
Macchiaverni, P., Gehring, U., Rekima, A., Wijga, A. H. & Verhasselt, V., 1 May 2022, In: Nutrients. 14, 10, 2095.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Allergen shedding in human milk: could it be key for immune system education and allergy prevention?
Macchiaverni, P., Rekima, A., van den Elsen, L., Renz, H. & Verhasselt, V., Sept 2021, In: The Journal of Allergy and Clinical Immunology. 148, 3, p. 679-688 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access26 Link opens in a new tab Citations (Scopus)
Projects
- 2 Finished
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Determinants of human milk-mediated protective immunity against COVID-19
Verhasselt, V. (Investigator 01), Macchiaverni, P. (Investigator 02), van den Elsen, L. (Investigator 03), Imrie, A. (Investigator 04), Rodriguez, J. (Investigator 05), McGuire, M. (Investigator 06), Kollmann, T. (Investigator 07) & Boss, M. (Investigator 08)
Department of Health (Western Australia)
1/02/21 → 31/08/22
Project: Research
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Round 7 - Gateway to allergy prevention: Promoting an immunomodulatory breastmilk profile with maternal prebiotic supplementation
Verhasselt, V. (Investigator 01), Palmer, D. (Investigator 02), Prescott, S. (Investigator 03), Christopherson, C. (Investigator 04), Geddes, D. (Investigator 05), Macchiaverni, P. (Investigator 06), van den Elsen, L. (Investigator 07) & Murray, K. (Investigator 08)
Department of Health (Western Australia)
1/07/19 → 31/01/22
Project: Research