Nina Tirnitz-Parker

Dr

  • The University of Western Australia (M704), 35 Stirling Highway,

    6009 Perth

    Australia

  • 580 Citations
  • 14 h-Index
20052019
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Research Output 2005 2019

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Article
2018
3 Citations (Scopus)

Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

Gratte, F. D., Pasic, S., Olynyk, J. K., Yeoh, G. C. T., Tosh, D., Coombe, D. R. & Tirnitz-Parker, J. E. E., 1 Dec 2018, In : Scientific Reports. 8, 1, 4385.

Research output: Contribution to journalArticle

Open Access
Extracellular Matrix Proteins
Hepatocytes
Stem Cells
Serum
Liver
2017
5 Citations (Scopus)

Taurocholate Induces Biliary Differentiation of Liver Progenitor Cells Causing Hepatic Stellate Cell Chemotaxis in the Ductular Reaction: Role in Pediatric Cystic Fibrosis Liver Disease

Pozniak, K. N., Pearen, M. A., Pereira, T. N., Kramer, C. S. M., Kalita-De Croft, P., Nawaratna, S. K., Fernandez-Rojo, M. A., Gobert, G. N., Tirnitz-Parker, J. E. E., Olynyk, J. K., Shepherd, R. W., Lewindon, P. J. & Ramm, G. A., 1 Dec 2017, In : American Journal of Pathology. 187, 12, p. 2744-2757 14 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Taurocholic Acid
Chemotaxis
Cystic Fibrosis
Liver Diseases
3 Citations (Scopus)

The murine choline-deficient, ethionine-supplemented (CDE) diet model of chronic liver injury

Gogoi-Tiwari, J., Köhn-Gaone, J., Giles, C., Schmidt-Arras, D., Gratte, F. D., Elsegood, C. L., McCaughan, G. W., Ramm, G. A., Olynyk, J. K. & Tirnitz-Parker, J. E. E., 21 Oct 2017, In : Journal of Visualized Experiments. 2017, 128, e56138.

Research output: Contribution to journalArticle

Ethionine
Nutrition
Choline
Liver
Diet
2016
5 Citations (Scopus)

A disintegrin And Metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis

Müller, M., Wetzel, S., Köhn-Gaone, J., Chalupsky, K., Lüllmann-Rauch, R., Barikbin, R., Bergmann, J., Wöhner, B., Zbodakova, O., Leuschner, I., Martin, G., Tiegs, G., Rose-John, S., Sedlacek, R., Tirnitz-Parker, N. E. E., Saftig, P. & Schmidt-Arras, D., 2016, In : Oncotarget. 7, 14, p. 17431-17441 11 p.

Research output: Contribution to journalArticle

Disintegrins
Metalloproteases
Homeostasis
Liver
Hepatocytes
1 Citation (Scopus)

A Transcriptomic Signature of Mouse Liver Progenitor Cells

Passman, A., Low, J., London, R., Tirnitz-Parker, N., Miyajima, A., Tanaka, M., Strick-Marchand, H., Darlington, G. J., Finch-Edmondson, M., Ochsner, S., Zhu, C., Whelan, J., Callus, B. & Yeoh, G., Aug 2016, In : Stem Cells International. 2016, p. 1-15

Research output: Contribution to journalArticle

Open Access
Stem Cells
Liver
Hepatocellular Carcinoma
Liver Diseases
Cell Line
13 Citations (Scopus)

Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury

Köhn-Gaone, J., Dwyer, B. J., Grzelak, C. A., Miller, G., Shackel, N. A., Ramm, G. A., Mccaughan, G. W., Elsegood, C. L., Olynyk, J. K. & Tirnitz-Parker, J. E. E., Jul 2016, In : American Journal of Pathology. 186, 7, p. 1762-1774 13 p.

Research output: Contribution to journalArticle

Thioacetamide
Ethionine
Choline
Stem Cells
Fibrosis
3 Citations (Scopus)
193 Downloads (Pure)

Identification of a thalidomide derivative that selectively targets tumorigenic liver progenitor cells and comparing its effects with lenalidomide and sorafenib

Woo, K., Stewart, S. G., Kong, G. S., Finch-Edmondson, M. L., Dwyer, B. J., Yeung, S. Y., Abraham, L. J., Kampmann, S. S., Diepeveen, L. A., Passman, A. M., Elsegood, C. L., Tirnitz-Parker, J. E. E., Callus, B. A., Olynyk, J. K. & Yeoh, G. C. T., 14 Sep 2016, In : European Journal of Medicinal Chemistry. 120, p. 275-283

Research output: Contribution to journalArticle

Open Access
File
Thalidomide
Liver
Stem Cells
Derivatives
Cells
2014
15 Citations (Scopus)

Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation

Prakoso, E., Tirnitz-Parker, N., Clouston, A. D., Kayali, Z., Lee, A., Gan, E., Ramm, G. A., Kench, J. G., Bowen, D. G., Olynyk, J. K., McCaughan, G. W. & Shackel, N. A., Dec 2014, In : Liver Transplantation. 20, 12, p. 1508-1519

Research output: Contribution to journalArticle

Hepacivirus
Liver Transplantation
Hepatocytes
Stem Cells
Recurrence
14 Citations (Scopus)

Role of TWEAK in coregulating liver progenitor cell and fibrogenic responses

Tirnitz-Parker, N., Olynyk, J. & Ramm, G. A., 2014, In : Hepatology. 59, 3, p. 1198-1201

Research output: Contribution to journalArticle

2013
20 Citations (Scopus)

Iron and hepatic carcinogenesis

Tirnitz-Parker, N., Glanfield, A., Olynyk, J. & Ramm, G. A., 2013, In : Critical Reviews in Oncogenesis. 18, 5, p. 391-407

Research output: Contribution to journalArticle

43 Citations (Scopus)

The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury

Grzelak, C. A., Martelotto, L. G., Sigglekow, N. D., Patkunanathan, B., Ajami, K., Calabro, S. R., Dwyer, B. J., Tirnitz-Parker, N., Watkins, D. N., Warner, F. J., Shackel, N. A. & Mccaughan, G. W., 2013, In : Journal of Hepatology. 60, 1, p. 143-151

Research output: Contribution to journalArticle

2012
32 Citations (Scopus)

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice

Delima, R., Chua, A., Tirnitz-Parker, N., Gan, E. K., Croft, K., Graham, R., Olynyk, J. & Trinder, D., 2012, In : Hepatology. 56, p. 585-592

Research output: Contribution to journalArticle

2011
13 Citations (Scopus)

Expansion and Hepatocytic Differentiation of Liver Progenitor Cells In Vivo Using a Vascularized Tissue Engineering Chamber in Mice

Forster, N., Palmer, J. A., Yeoh, G., Ong, W. C., Mitchell, G. M., Slavin, J., Tirnitz-Parker, N. & Morrison, W. A., 2011, In : Tissue Engineering. Part C. Methods. 17, 3, p. 1-8

Research output: Contribution to journalArticle

2010
13 Citations (Scopus)

Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis

Chua, A., Delima, R. D., Morgan, E., Herbison, C. E., Tirnitz-Parker, N., Graham, R., Fleming, R. E., Britton, R. S., Bacon, B. R., Olynyk, J. & Trinder, D., 2010, In : Journal of Hepatology. 52, 2010, p. 425-431

Research output: Contribution to journalArticle

108 Citations (Scopus)

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Is a Mitogen for Liver Progenitor Cells

Tirnitz-Parker, N., Viebahn, C., Jakubowski, A., Klopcic, B., Olynyk, J., Yeoh, G. & Knight, B., 2010, In : Hepatology. 52, 1, p. 291-302

Research output: Contribution to journalArticle

2009
59 Citations (Scopus)

Lymphotoxin-β Receptor Signaling REgulates Heptatic Stellate Cell Function and Wound Healing in a Murine Model of Chronic Liver Injury

Ruddell, R. G., Knight, B., Tirnitz-Parker, J. E. E., Akhurst, B., Summerville, L., Subramaniam, V. N., Olynyk, J. & Ramm, G. A., 2009, In : Hepatology. 49, 1, p. 227-239

Research output: Contribution to journalArticle

Lymphotoxin-beta
Lymphotoxin-alpha
Hepatic Stellate Cells
Wound Healing
Liver
2008
51 Citations (Scopus)

C-kit Inhibition by Imatinib Mesylate Attenuates Progenitor Cell Expansion and Inhibits Liver Tumor Formation in Mice

Knight, B., Tirnitz-Parker, J. E. E. & Olynyk, J., 2008, In : Gastroenterology. 135, 3, p. 969-979

Research output: Contribution to journalArticle

Stem Cells
Liver
Neoplasms
Ethionine
Choline
2007
85 Citations (Scopus)
Ethionine
Nutrition
Choline
Liver
Hepatocytes
2006
16 Citations (Scopus)

Evaluation of the "Cellscreen" system for proliferation studies on liver progenitor cells

Viebahn, C., Tirnitz-Parker, N., Olynyk, J. & Yeoh, G., 2006, In : European Journal of Cell Biology. 85, 12, p. 1265-1274

Research output: Contribution to journalArticle

Stem Cells
Liver
Intercellular Signaling Peptides and Proteins
Suspensions
Cell Culture Techniques
2005
22 Citations (Scopus)
Oncostatin M
Acute-Phase Reaction
Stem Cells
Cell Culture Techniques
Liver