Nicole Smith

Dr, PhD W.Aust.

  • The University of Western Australia (M313), 35 Stirling Highway,

    6009 Crawley

    Australia

  • 290 Citations
  • 11 h-Index
20072021
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Personal profile

Biography

NHMRC Research Fellow
Honorary NRP Research Fellow

B.Science (Chemistry & Biochemistry), The University of Sydney, NSW, Australia

PhD (Chemistry), The University of Western Australia (2010), WA, Australia

Postdoc, The Australian National University (2011-2012), Canberra, ACT, Australia

Agence Nationale de la Recherché Postdoctoral Fellow, Institut Européen de Chimie et Biologie (2010-2011), Bordeaux, France

Roles and responsibilities

PhD Students

Pari Tackle - Co-supervised with Ryan Lister and Swaminatha Iyer

Ruhani Singh (Completed) - Co-supervised with Swaminatha Iyer and Lee Yong Lim

Masters Students

2017-2018 - Sara Tai - co-supervised with Swaminatha Iyer

Honours Students

2017-2018 Amy Kretzmann, co-supervised with Archa Fox, Iyer Swaminatha

2017-2018 Chloe Gray, co-supervised with Melinda Fitzgerald

2017-2018 Nikolas Gavriel, co-supervised with Melinda Fitzgerald

2016-2017 Michelle Nguyen, co-supervised with Sarah Dunlop and Lindy Fitzgerald - Awarded 1st Class Honours

Exchange students

2017-2018 Abigail Egid - 3rd Year B.Sc (Hons) student from the University of Bath, UK.

2017-2018 Melanie Grigg - 3rd Year B.Sc (Hons) student from the University of Bath, UK.

2015-2016 Daniella Zimmerman - 3rd Year B.Sc (Hons) student from the University of Bath, UK. Co-supervised with Sarah Dunlop.

2014-2015 Charlotte Bailey– 3rd Year B.Sc (Hons) student from the University of Bath, UK. Co-supervised with Sarah Dunlop.

2013-2014 Ivana Gachulincová – 3rd Year B.Sc (Hons) student from the University of Bath, UK, (Won 1st place in the Bath Student Exchange Program). Co-supervised with Sarah Dunlop.

2013-2014 Andressa Finkler Staudt - pharmacy student from the Universidad Federal do Rio Grande do Sul, (Won 1st Place in the Science Without Borders Program for her final research presentation). Co-supervised with Sarah Dunlop


Undergraduate students:

2015 Saiuj Bhat - Perkins Vacation Scholarship from the Harry Perkins Institute of Medical Research. Co-supervised with Pilar Blancafort and Ryan Lister.

Teaching
CHEM1004 - Biological Chemistry
MSCI4098/MSCI4099 - Seminar Appraisal and Presentation

Committees

Faculty of Science Consumer and Community Engagement Committee

School of Molecular Sciences Consumer and Community Engagement Committee

Funding overview

2017 NHMRC Boosting Dementia Research Leadership Fellowship

2017 Neurotrauma Research Program Fellowship

2017 National Breast Cancer Foundation Innovator Grant CI: Smith, Lister, Clark, AI: Hurley, Redfern, Saunders

2017 Australian Synchrotron Beamtime. CIs: Hackett, Smith, Fitzgerald

2017 Cancer Council WA, Collaborative Cancer Grant Scheme CI: Smith, Evans, Tang, Sorolla, AI: Lister, Hurley

2017 UWA Research Collaboration Award – “Developing a 3D mimic of the brain” – CIs: Iyer, Fitzgerald, Choi, Smith, Evans, Thordarson, Martin, Franz, Davies

2016 Neurotrauma Research Program, CI: Smith, AI: Hurley, Fitzgerald and Dunlop - Targeting four-stranded DNA conformations to enable axonal regeneration following neurotrauma

2015 National Health and Medical Research Council, CIs: Fitzgerald, Dunlop, Iyer, Smith - Targeted nanoparticles to deliver novel combinatorial treatments for secondary degeneration following neurotrauma

2015 Neurotrauma Research Program, CI: Smith AI: Dunlop, Iyer, House, Feindel - Using nanotechnology to prevent localised, as well as remote, inflammation and breakdown of the blood brain barrier following neurotrauma

2015 The Raine Medical Research Foundation Healy Research Collaboration award, CI: Smith PI: Hurley (University of Arizona, Tetragene Ltd (Salt Lake City) - Targeting epigenetic markers to modulate G-quadruplex DNA topology as a novel therapeutic strategy for cancer

2014 Neurotrauma Research Program, CI: Smith AI: Dunlop, Iyer, House - Crossing the Blood Brain Barrier: Towards intravenous delivery of theranostic nanoparticles for targeted therapy following neurotrauma

Teaching overview

CHEM1004 - Biological Chemistry
MSCI4098/MSCI4099 - Seminar Appraisal and Presentation

Research

> Unusual nucleic acid structures in Breast Cancer and Fibrosis

> Targeting G-quadruplex DNA as a novel therapeutic strategy for Alzheimer’s and Frontotemporal Dementia

>Novel mechanism-based enzyme inhibitors for the treatment of Neurotrauma

Keywords

  • Gene regulation and neuroscience

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Nanoparticles Chemical Compounds
G-Quadruplexes Medicine & Life Sciences
Ligands Chemical Compounds
Polyethylene glycols Engineering & Materials Science
Chemical reactivity Chemical Compounds
Wounds and Injuries Medicine & Life Sciences
Aldehydes Chemical Compounds
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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2018

  • 290 Citations
  • 11 h-Index
  • 30 Article
  • 1 Abstract/Meeting Abstract
  • 1 Literature review
  • 1 Doctoral Thesis
Oligodendroglia
Wounds and Injuries
Secondary Ion Mass Spectrometry
Cellular Structures
Lipid Peroxidation

Direct correlation of PNIPAM thermal transition and magnetic resonance relaxation of iron oxide nanoparticles

Taib, N. I., Agarwal, V., Smith, N. M., Woodward, R. C., Pierre, T. G. S. & Iyer, K. S. 1 Nov 2017 In : Materials Chemistry Frontiers. 1, 11, p. 2335-2340 6 p.

Research output: Contribution to journalArticle

7 Citations

Magnetically recoverable Fe3O4@Au-coated nanoscale catalysts for the A3-coupling reaction

Munshi, A. M., Shi, M., Thomas, S. P., Saunders, M., Spackman, M. A., Iyer, K. S. & Smith, N. M. 2017 In : Dalton Transactions. 46, 16, p. 5133-5137 5 p.

Research output: Contribution to journalArticle

Alkynes
Aldehydes
Discrete Fourier transforms
Amines
Electrostatics
Open Access
1 Citations
serums
coronas
Blood Proteins
Nanoparticles
proteins

Prizes

Healy Research Collaboration award

Nicole Smith (Recipient), 2015

Prize/award: Prize