Monika Murcha

Dr, BSc PhD W.Aust.

  • The University of Western Australia (M310), 35 Stirling Highway, Room 3.48, Bayliss Building, Perth campus

    6009 Perth

    Australia

  • 1711 Citations
  • 25 h-Index
19992019
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Personal profile

Biography

Dr Murcha (PhD UWA) was awarded an ARC postdoctoral fellowship in 2006 at the University of Western Australia followed by an ARC Future Fellowship in 2014 where she founded her own laboratory to understand the components and underlying processes of plant mitochondrial biogenesis.

Future research

Dr Murcha's research focus is to unravel the underlying mechanisms of protein import and macromolecule targeting, key regulatory elements governing mitochondrial activity and thus cellular activity, plant growth and responses to stress. Using a range of genetic, biochemical and molecular approaches the molecular mechanisms that regulate these processes are being investigated.

Funding overview

2005: University of Western Australia Research Grants Scheme, $20,000.
Characterisation of novel protein transporters in Arabidopsis.
2008: ARC Postdoctoral Fellowship awarded for 4 years, this proposal was ranked A+, in the top third of all successful fellowships. Functional characterisation of novel transport proteins in plants
2010: University of Western Australia Research Development Award, $29,000. Characterisation of the role of a stress inducible transport protein in the mitochondrial inner membrane.
2013: STINT, Swedish Foundation for International Co-operation in Research and Higher Education, $240 000. Whelan J, Murcha M, Glaser E. Systems biology approaches to study intracellular protein transport and organellar biogenesis in plants.
2013: ARC Future Fellowship, $723,320. Characterisation of the Regulators of Mitochondrial Biogenesis in Arabidopsis thaliana
2015: Murcha, Soll and Drouard. ARC Discovery Project, $527,279 Modifying mitochondria: the targeting of macromolecules to alter mitochondrial function.
2015-2017: Murcha and Soll. DAAD/G08 Research Co-operation Scheme, $39,000. Characterisation of PRAT protein in mitochondria and chloroplast.

Teaching overview

BIOC5001Advanced Biochemistry and Molecular Biology Techniques, course co-ordinator and lecturer.
SCIE4001 The Objective and Application of Genomics, lecturer.
BIOC4001 Advanced Studies on Biochemistry and Molecular Biology, lecturer.
GENE5001Advanced Genomic Techniques, course co-ordinator.
BIOC3005 Cellular Biochemistry, lecturer.

Research

Mitochondrial biogenesis
Protein targeting
Arabidopsis

Keywords

  • Mitochondrial biogenesis
  • Protein import
  • Plant molecular biology
  • Sub-cellular localisation
  • Genetic manipulation of plants

Fingerprint Dive into the research topics where Monika Murcha is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 14 Similar Profiles
Arabidopsis Medicine & Life Sciences
Mitochondria Medicine & Life Sciences
Mitochondrial Proteins Medicine & Life Sciences
imports Agriculture & Biology
mitochondria Agriculture & Biology
Mitochondrial Membranes Medicine & Life Sciences
Proteins Medicine & Life Sciences
proteins Agriculture & Biology

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1999 2019

An interstitial peptide is readily processed from within seed proteins

Pouvreau, B., Fenske, R., Ivanova, A., Murcha, M. W. & Mylne, J. S., 1 Aug 2019, In : Plant Science. 285, p. 175-183 9 p.

Research output: Contribution to journalArticle

Seeds
asparaginylendopeptidase
peptides
Peptides
albumins
1 Citation (Scopus)

Accumulation of endogenous peptides triggers a pathogen stress response in Arabidopsis thaliana

Kmiec, B., Branca, R. M. M., Berkowitz, O., Li, L., Wang, Y., Murcha, M. W., Whelan, J., Lehtiö, J., Glaser, E. & Teixeira, P. F., 1 Nov 2018, In : Plant Journal. 96, 4, p. 705-715 11 p.

Research output: Contribution to journalArticle

Arabidopsis
stress response
Arabidopsis thaliana
peptides
Peptides
4 Citations (Scopus)

A Common Peptidolytic Mechanism for Targeting Peptide Degradation in Mitochondria and Chloroplasts

Kmiec, B., Branca, R. M. M., Murcha, M. W., Lehtiö, J., Glaser, E. & Teixeira, P. F., 2018, In : Molecular Plant. 11, 2, p. 342–345

Research output: Contribution to journalLetter

4 Citations (Scopus)

An assembly factor promotes assembly of flavinated SDH1 into the succinate dehydrogenase complex

Belt, K., Van Aken, O., Murcha, M., Millar, A. & Huang, S., Aug 2018, In : Plant Physiology. 177, 4, p. 1439-1452

Research output: Contribution to journalArticle

Open Access
succinate dehydrogenase (quinone)
Flavin-Adenine Dinucleotide
Succinate Dehydrogenase
succinic acid
phenotypic variation
152 Downloads (Pure)

Antimalarial herbicides and herbicidal antimalarials: Exploiting the plant-Plasmodium connection

Corral, M., 2018, (Unpublished)

Research output: ThesisDoctoral Thesis

File
antimalarials
Plasmodium
herbicides
parasites
herbicide resistance

Projects 2006 2017