Miranda Grounds

Emeritus Professor, BSc W.Aust., PhD Lond.

  • The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

  • 5284 Citations
  • 40 h-Index
1992 …2020
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Research Output 1992 2018

Vesicular Glutamate Transport Protein 1
Motor Neurons
Spinal Cord
Carisoprodol
Sarcopenia
Long Noncoding RNA
Inbred mdx Mouse
Taurine
Transfer RNA
Muscle
1 Citations
Regenerative Medicine
Tissue Engineering
Bioengineering
Drug Industry
Stem Cells
2017
4 Citations
Open Access
Inbred mdx Mouse
Taurine
taurine
mice
Growth

Exploration of non-coding RNA expression in developing and dystrophic skeletal muscle

Butchart, L. C., 2017, (Unpublished)

Research output: ThesisDoctoral Thesis

File
Untranslated RNA
Skeletal Muscle
Taurine
Growth
Inbred mdx Mouse
1 Citations

IGF1 stimulates greater muscle hypertrophy in the absence of myostatin in male mice

Hennebry, A., Oldham, J., Shavlakadze, T., Grounds, M. D., Sheard, P., Fiorotto, M. L., Falconer, S., Smith, H. K., Berry, C., Jeanplong, F., Bracegirdle, J., Matthews, K., Nicholas, G., Senna-Salerno, M., Watson, T. & McMahon, C. D., Aug 2017, In : Journal of Endocrinology. 234, 2, p. 187-200 14 p.

Research output: Contribution to journalArticle

6 Citations

MicroRNA expression patterns in post-natal mouse skeletal muscle development

Lamon, S., Zacharewicz, E., Butchart, L. C., Orellana, L., Mikovic, J., Grounds, M. D. & Russell, A. P., 7 Jan 2017, In : BMC Genomics. 18, 1, 52

Research output: Contribution to journalArticle

Open Access
Muscle Development
MicroRNAs
Skeletal Muscle
Quadriceps Muscle
Mammals

NEUROMUSCULAR JUNCTION-RELATED GENE EXPRESSION AND PHYSICAL PERFORMANCE IN OLDER MEN: FINDINGS FROM THE HERTFORDSHIRE SARCOPENIA STUDY (HSS)

Granic, A., Westbury, L. D., Syddall, H. E., Patel, H. P., Dodds, R., Cooper, C., Cozens, G., Grounds, M. D., Shavlakadze, T. & Sayer, A. A., Jul 2017, In : Age and Ageing. 46, 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

New insights into lipid accumulation in dysferlin deficient muscular dystrophies

Grounds, M., White, R., Lloyd, E. & Pinniger, G., Oct 2017, In : Neuromuscular Disorders. 27, p. S146-S147 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

5 Citations
Inbred mdx Mouse
Duchenne Muscular Dystrophy
Acetylcysteine
Muscles
Body Weight
2 Citations
Sarcopenia
Sciatic Nerve
Axons
Skeletal Muscle
S100 Proteins
6 Citations

Silk fibroin scaffolds with muscle-like elasticity support in vitro differentiation of human skeletal muscle cells

Chaturvedi, V., Naskar, D., Kinnear, BF., Grenik, E., Dye, DE., Grounds, M. D., Kundu, SC. & Coombe, DR., 2017, In : Journal of Tissue Engineering and Regenerative Medicine. 11, 11, p. 3178–3192 15 p.

Research output: Contribution to journalArticle

Open Access
Fibroins
Silk
Elasticity
Skeletal Muscle Fibers
Scaffolds

Taurine: an anti-inflammatory and antioxidant with strong potential benefits for Duchenne muscular dystrophy

Arthur, P., Terrill, J. & Grounds, M., Oct 2017, In : Neuromuscular Disorders. 27, p. S191-S192 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2016
7 Citations

A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice

Krishnan, V. S., White, Z., Mcmahon, C. D., Hodgetts, S., Fitzgerald, M., Shavlakadze, T., Harvey, A. & Grounds, M., 1 May 2016, In : Journal of Neuropathology and Experimental Neurology. 75, 5, p. 464-478

Research output: Contribution to journalArticle

Open Access
File
Sarcopenia
Sciatic Nerve
Axons
Choline O-Acetyltransferase
Peripheral Nerves
9 Citations
Hypertrophy
Muscles
Quadriceps Muscle
Skeletal Muscle
Extremities
17 Citations
Inbred mdx Mouse
Duchenne Muscular Dystrophy
Taurine
Skeletal Muscle
Muscles
11 Citations

Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy

Terrill, J., Duong, M., Turner, R., Le Guiner, C., Boyatzis, A., Kettle, A. J., Grounds, M. & Arthur, P., Oct 2016, In : Redox Biology. 9, p. 276-286 11 p.

Research output: Contribution to journalArticle

Open Access
Oxidative stress
Duchenne Muscular Dystrophy
Muscular Dystrophies
Taurine
Oxidative Stress
14 Citations
Long Noncoding RNA
MicroRNAs
Skeletal Muscle
Untranslated RNA
Growth
16 Citations
Open Access
Sarcopenia
Autophagy
Inbred C57BL Mouse
Exercise
Muscles
2015
19 Citations
Open Access
File
PTEN Phosphohydrolase
Phosphorylation
Oxidative stress
Skeletal Muscle Fibers
Sulfhydryl Compounds

Factors controlling movement of skeletal muscles

Grounds, M., 2015, In : POS. 48, 3, p. 270-271

Research output: Contribution to journalArticle

Cells
Contraction
Nerve
Membrane
Artificial
12 Citations

Interactions between skeletal muscle myoblasts and their extracellular matrix revealed by a serum free culture system

Chaturvedi, V., Dye, D. E., Kinnear, B. F., Van Kuppevelt, T. H., Grounds, M. & Coombe, D. R., 2015, In : PLoS One. 10, 6, p. 1-27

Research output: Contribution to journalArticle

Open Access
Skeletal Myoblasts
myoblasts
Myoblasts
extracellular matrix
Extracellular Matrix
20 Citations
Open Access
File
Inbred mdx Mouse
Duchenne Muscular Dystrophy
Taurine
Cysteine
Liver
2014
25 Citations

Dystropathology increases energy expenditure and protein turnover in the Mdx mouse model of Duchenne muscular dystrophy

Radley-Crabb, H., Marini, J. C., Sosa, H. A., Castillo, L. I., Grounds, M. & Fiorotto, M. L., 2014, In : PLoS One. 9, 2, p. 13pp

Research output: Contribution to journalArticle

Open Access
Inbred mdx Mouse
muscular dystrophy
Duchenne Muscular Dystrophy
protein metabolism
energy expenditure
28 Citations

Imaging deep skeletal muscle structure using a high-sensitivity ultrathin side-viewing optical coherence tomography needle probe

Yang, X., Lorenser, D., Mclaughlin, R., Kirk, R., Edmond, M., Simpson Cather, M., Grounds, M. & Sampson, D., 2014, In : Biomedical Optics Express. 5, 1, p. 136-148

Research output: Contribution to journalArticle

skeletal muscle
Optical Coherence Tomography
Cellular Structures
needles
Needles
28 Citations

Lean mass, muscle strength and gene expression in community dwelling older men: findings from the hertfordshire sarcopenia study (HSS)

Patel, HP., Al-Shanti, N., Davies, LC., Barton, SJ., Grounds, M., Tellam, RL., Stewart, CE., Cooper, CC. & Sayer, AA., 2014, In : Calcified Tissue International. 95, p. 308-316

Research output: Contribution to journalArticle

13 Citations

Lifelong exercise and locally produced insulin-like growth factor-1 (IGF-1) have a modest influence on reducing age-related muscle wasting in mice

Mcmahon, CD., Chai, R., Crabb, H., Watson, T., Matthews, KG., Sheard, P., Soffe, Z., Grounds, M. & Shavlakadze, T., Dec 2014, In : Scandinavian Journal of Medicine and Science in Sports. 24, 6, p. e423-e435

Research output: Contribution to journalArticle

Somatomedins
Muscles
Skeletal Muscle
Sarcopenia
Quadriceps Muscle
16 Citations

Lipid accumulation in dysferlin-deficient muscles

Grounds, M., Terrill, J., Radley-Crabb, H., Robertson, T., Papadimitriou, J., Spuler, S. & Shavlakadze, T., 2014, In : American Journal of Pathology. 184, 6, p. 1668-1676

Research output: Contribution to journalArticle

Muscular Diseases
Adipocytes
Psoas Muscles
Lipogenesis
Lipids
23 Citations
Sarcopenia
Denervation
Muscle
Skeletal Muscle
Ribosomal Protein S6
17 Citations
skeletal muscle
Muscular Dystrophies
Optical Coherence Tomography
attenuation coefficients
mice
5 Citations

Protein thiol oxidation does not change in skeletal muscles of aging female mice

Tohma, H., El-Shafey, A., Croft, K., Shavlakadze, T., Grounds, M. & Arthur, P., Feb 2014, In : Biogerontology. 15, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citations

Regenerative Medicine: the challenge of translation

Rosenthal, N. & Grounds, M., 2014, In : International Journal of Biochemistry and Cell Biology. 56, p. 2-3

Research output: Contribution to journalLetter

22 Citations

Skeletal Muscle Degeneration and Regeneration in Mice and Flies

Rai, M., Nongthomba, U. & Grounds, M., 2014, In : Current Topics in Developmental Biology. 108, p. 247-281

Research output: Contribution to journalArticle

Diptera
Regeneration
Skeletal Muscle
Muscles
Hypertrophy
16 Citations
Muscle
Regeneration
Skeletal Muscle
Muscles
Muscle Development
2013
24 Citations

Impact of fasting on the rhythmic expression of myogenic and metabolic factors in skeletal muscle of adult mice

Shavlakadze, T., Anwari, T., Soffe, Z., Cozens, G., Mark, P., Gondro, C. & Grounds, M., 1 Jul 2013, In : American Journal of Physiology- Cell Physiology. 305, 1, p. C26-C35

Research output: Contribution to journalArticle

Open Access
105 Citations

New horizons in the pathogenesis, diagnosis and management of sarcopenia

Sayer, A. A., Robinson, S. M., Patel, H. P., Shavlakadze, T., Cooper, C. & Grounds, M., 2013, In : Age and Ageing. 42, 2, p. 145-150

Research output: Contribution to journalArticle

Open Access
68 Citations

Oxidative stress and pathology in muscular dystrophies: focus on protein thiol oxidation and dysferlinopathies

Terrill, J., Crabb, H., Iwasaki, T., Lemckert, F. A., Arthur, P. & Grounds, M., Sep 2013, In : The FEBS Journal. 280, 17, p. 4149-4164

Research output: Contribution to journalArticle

Open Access
Oxidative stress
Muscular Dystrophies
Pathology
Sulfhydryl Compounds
Oxidative Stress
18 Citations

Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice

Huynh, T., Uaesoontrachoon, K., Quinn, J. L., Tatem, K. S., Heier, C., Van Der Meulen, J. H., Yu, Q., Harris, M., Nolan, C. J., Haegeman, G., Grounds, M. & Nagaraju, K., 2013, In : Journal of Pathology. 231, 2, p. 223-235

Research output: Contribution to journalArticle

11 Citations

Short-term feed deprivation rapidly induces the protein degradation pathway in skeletal muscles of young mice

Shavlakadze, T., Soffe, Z., Anwari, T., Cozens, G. & Grounds, M., 2013, In : Journal of Nutrition. 143, 4, p. 403-409

Research output: Contribution to journalArticle

Open Access
36 Citations

Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice

Jackaman, C., Radley-Crabb, H. G., Soffe, Z., Shavlakadze, T., Grounds, M. & Nelson, D. J., 2013, In : Aging Cell. 12, 3, p. 345-357

Research output: Contribution to journalArticle