• The University of Western Australia (M519), 35 Stirling Highway,

    6009 Perth


Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile


Michael is the Node Leader for Metabolomics Australia (MA), based at the Harry Perkins Institute (North) building.  MA is an NCRIS flagship capability managed by the Centre for Microscopy, Characterisation and Analysis at UWA.   Michaels' interests include hormone analysis using LCMS and drug pharmacokinetics in humans and animal models of disease. In 2012 Michael established a reference assay for the analysis of Vitamin D in serum. The MA node is involved in several national projects studying Vitamin D and its effects on health outcomes in humans. The facility is recognised by the CDC for the analysis of Vitamin D in human serum and has recently passed certification for accuracy and precision for the 5th year in a row.  The MA node also supports multi-disciplinary research in plant, oceans and natural product discovery applications using GCMS, LCMS and high resolution mass spectrometry.

Roles and responsibilities

Technique group leader in Mass Spectrometry and Metabolomics
WA Node Leader (Metabolomics Australia)

Funding overview

National Collaborative Research Infrastructure Strategy, 2019-23, $2.5M
Bioplatforms Australia and WA State government funding for Metabolomics
Investigator:Michael Clarke (CI) 

Rural Industries Research & Development Corporation, 2016, $130,500
Development of honeybee products from a biodiversity hotspot
Katherine Hammer, Connie Locher, Michael Clarke (CI)

MS Research Australia, 2014, $180,000
Project Title: Vitamin D metabolites and risk of multiple sclerosis in the Ausimmune Study
Investigators: Robyn Lucas, Anne-Louise Ponsonby, Bruce Taylor, Lucinda Black, Michael Clarke(CI)

Telethon-Perth Children’s Hospital Research Fund 2014, $ $200,000
Project title: Improving gut biodiversity with soluble fibre in early life to prevent inflammatory disease – a pilot study to study effects on early immune development
Investigators: Susan Prescott, Desiree De Silva, Charles Mackay, Michael Clarke (CI), Rae-Chi Huang

National Collaborative Research Infrastructure Strategy (NCRIS 2) 2013-14, $650,000
Bioplatforms Australia CRIS funding for Metabolomics
Investigators: Steven Smith, Michael Clarke (CI)

Bioplatforms Australia ex Education Investment Fund (EIF) 2011, $800,000
Investigators: Steven Smith, Michael Clarke (CI)

Royal Perth Hospital Medical Research Foundation Grant 2008, A$10K
Project Title: Correlation between Skin Conductance Monitoring, Surgical Stress Index and stress hormone plasma levels for assessment of intraoperative depth of analgesia
Investigators: Thomas Ledowski, Kevin Croft, Michael Clarke (CI)

Previous positions

Research Development Advisor
Faculty of Medicine, Dentistry and Health Sciences
University of Western Australia

Senior Medical Scientist
Core Chemical Pathology and Biochemistry
HPLC and Mass Spectrometry Laboratory
PathWest, Royal Perth Hospital

Current projects

D-Light project, see http://telethonkids.org.au/d-light/

Teaching overview

Semester 2,2009
Curtin University of Technology
Teaching second year Clinical Biochemistry students with emphasis on laboratory techniques


Metabolomics in multiple sample types
Vitamin D metabolism in humans
Drug pharmacokinetics in a sheep model of human disease
Vitamin E metabolism in humans
Antioxidants in health and disease
Method development in Mass Spectrometry



Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research expertise keywords

  • Mass spectrometry
  • Biochemistry service
  • Antioxidants
  • Cardiovascular nutrition
  • Vitamin D
  • Steroids
  • GCMS
  • LCMS
  • Metabolomics


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Collaborations and top research areas from the last five years

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