• The University of Western Australia (M503), 35 Stirling Highway,

    6009 Perth

    Australia

  • 7220 Citations
  • 42 h-Index
19992024
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Personal profile

Biography

Professor Mark Nicol is a medical microbiologist in the Division of Infection and Immunity in the School of Biomedical Sciences. He also holds an honorary appointment at the University of Cape Town, South Africa. He has a passion for using modern molecular tools to understand complex microbial communities, investigating how imbalances in these communities cause illness and to develop and test better diagnostics for infections, particularly for diseases relating to poverty. 

Specific focus areas of Dr Nicol’s research are the pathogenesis and diagnosis of respiratory infection in children, development, evaluation and implementation of novel diagnostic tests for tuberculosis, the cascade of care for patients with drug-resistant tuberculosis and the role of the microbiome in early childhood development and illness. Professor Nicol has done seminal work on diagnostics for tuberculosis in children and adults, which has provided an evidence base for the new molecular tuberculosis tests used worldwide, and has contributed to many WHO policy recommendations and guidelines. 

Dr Nicol has successfully competed for grants from major international funders, including recent funding from the National Institutes of Health, the Bill and Melinda Gates Foundation and Wellcome Trust. He is a member of the advisory board for several large biotech companies and grant consortia, and a member of the International Interview Panel for the Wellcome Trust. 

A major emphasis is placed on the development of the next generation of researchers, and many of Dr Nicol's students have received international fellowships as well as awards at scientific meetings.

External positions

Honorary Professor of Microbiology, University of Cape Town

1 Jan 2019 → …

Fingerprint Dive into the research topics where Mark Nicol is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Tuberculosis Medicine & Life Sciences
South Africa Medicine & Life Sciences
HIV Medicine & Life Sciences
Mycobacterium tuberculosis Medicine & Life Sciences
Sputum Medicine & Life Sciences
Pulmonary Tuberculosis Medicine & Life Sciences
Rifampin Medicine & Life Sciences
Multidrug-Resistant Tuberculosis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1999 2019

Brief Report: Real-World Performance and Interobserver Agreement of Urine Lipoarabinomannan in Diagnosing HIV-Associated Tuberculosis in an Emergency Center

Van Hoving, D. J., Lahri, S., Lategan, H. J., Nicol, M. P., Maartens, G. & Meintjes, G., 1 May 2019, In : Journal of acquired immune deficiency syndromes (1999). 81, 1, p. e10-e14

Research output: Contribution to journalArticle

Point-of-Care Systems
Tuberculosis
Emergencies
HIV
Urine
1 Citation (Scopus)

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Schutz, C., Barr, D., Andrade, B. B., Shey, M., Ward, A., Janssen, S., Burton, R., Wilkinson, K. A., Sossen, B., Fukutani, K. F., Nicol, M., Maartens, G., Wilkinson, R. J. & Meintjes, G., Jul 2019, In : PLoS Medicine. 16, 7, p. e1002840

Research output: Contribution to journalArticle

Open Access
Tuberculosis
Cohort Studies
HIV
Prospective Studies
Mortality
4 Citations (Scopus)

Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis

Di Tanna, G. L., Raza Khaki, A., Theron, G., McCarthy, K., Cox, H., Mupfumi, L., Trajman, A., Sodai Zijenah, L., Mason, P., Bandason, T., Durovni, B., Bara, W., Hoelscher, M., Clowes, P., Mangu, C., Chanda, D., Pym, A., Mwaba, P., Cobelens, F., Nicol, M. P. & 4 othersDheda, K., Churchyard, G., Fielding, K. & Metcalfe, J. Z., 1 Feb 2019, In : The Lancet Global Health. 7, 2, p. e191-e199

Research output: Contribution to journalArticle

Open Access
Meta-Analysis
Tuberculosis
Sputum
HIV
Mortality
Multiplex Polymerase Chain Reaction
Sputum
Pneumocystis carinii
Inpatients
Real-Time Polymerase Chain Reaction

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients

Schutz, C., Ward, A., Burton, R., Nicol, M. P., Blumenthal, U., Meintjes, G. & Kerkhoff, A. D., 28 Aug 2019, In : Southern African Journal of HIV Medicine. 20, 1, 10 p., 978.

Research output: Contribution to journalArticle

Open Access

Projects 2020 2024

  • 1 Not started