• The University of Western Australia (M318), 35 Stirling Highway,

    6009 Perth


  • 471 Citations
  • 13 h-Index
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Personal profile


The Burn Injury Research Unit covers all aspects of burn injury, from improving injury assessment through the use of novel technologies, to advanced wound biomaterials, understanding the biology of scar formation and rehabilitation after injury
A primary research focus is the response and integration of the bone marrow, nervous system and immune response to burn injury and how this impacts on the outcome. We are particularly interested in these systemic responses and how they influence healing, and have evidence now for cortical plasticity after burn injury, bone marrow responses affecting scar formation and systemic changes in peripheral nerves potentially caused by an immune mediator. Whilst most research on burn injury has, understandably, focused on topical intervention and the site of injury, a key aspect of our research is the hypothesis that these systemic responses are key to changing the healing process and improving the patient outcome. This has so far been borne out by our data showing long-term changes in these systems in response to burn injury that appear never to return to pre-injury states.


  • Reinnervation and injury
  • Scar formation and maintenance
  • Tissue regeneration
  • Epigenetic changes in dermal cells after injury

Fingerprint Dive into the research topics where Mark Fear is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Wounds and Injuries Medicine & Life Sciences
Burns Medicine & Life Sciences
Cicatrix Medicine & Life Sciences
Western Australia Medicine & Life Sciences
Population Medicine & Life Sciences
Skin Medicine & Life Sciences
Cohort Studies Medicine & Life Sciences
Morbidity Medicine & Life Sciences

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Research Output 2011 2019

  • 471 Citations
  • 13 h-Index
  • 54 Article
  • 3 Review article
  • 2 Conference paper
  • 1 Editorial

Burn induced nervous system morbidity among burn and non-burn trauma patients compared with non-injured people

Duke, J. M., Randall, S. M., Fear, M. W., Boyd, J. H., Rea, S. & Wood, F. M., 1 Aug 2019, In : Burns. 45, 5, p. 1041-1050 10 p.

Research output: Contribution to journalArticle

Nervous System
Wounds and Injuries
Peripheral Nervous System
Confidence Intervals
3 Citations (Scopus)

Carbon dioxide laser treatment in burn-related scarring: A prospective randomised controlled trial

Douglas, H., Lynch, J., Harms, K-A., Krop, T., Kunath, L., van Vreeswijk, C., McGarry, S., Fear, M. W., Wood, F. M., Murray, A. & Rea, S., Jun 2019, In : JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY. 72, 6, p. 863-870 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ephrin-A2 affects wound healing and scarring in a murine model of excisional injury

Wijeratne, D., Rodger, J., Stevenson, A., Wallace, H., Prêle, C. M., Wood, F. M. & Fear, M. W., May 2019, In : Burns. 45, 3, p. 682-690 9 p.

Research output: Contribution to journalArticle

Wound Healing

Genetic influence on scar height and pliability after burn injury in individuals of European ancestry: A prospective cohort study

Wallace, H. J., Cadby, G., Melton, P. E., Wood, F. M., Falder, S., Crowe, M. M., Martin, L. J., Marlow, K., Ward, S. V. & Fear, M. W., May 2019, In : Burns. 45, 3, p. 567-578 12 p.

Research output: Contribution to journalArticle

Open Access
Cohort Studies
Prospective Studies
Wounds and Injuries
1 Citation (Scopus)

TGF‐β‐induced fibrotic stress increases G‐quadruplex formation in human fibroblasts

Toshniwal, P., Nguyen, M., Guédin, A., Viola, H., Ho, D., Kim, Y., Bhatt, U., Bond, C., Hool, L., Hurley, L., Mergny, J-L., Fear, M., Wood, F., Swaminatha Iyer, K. & Smith, N., Nov 2019, In : FEBS Letters. 593, 22, p. 3149-3161 13 p.

Research output: Contribution to journalArticle

Wound Healing
Medical problems

Projects 2009 2023