Louise Winteringham

Dr, BSc Auck., MSc PhD W.Aust.

  • The University of Western Australia (M575), 35 Stirling Highway,

    6009 Perth

    Australia

  • 3205 Citations
  • 21 h-Index
19982018
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Personal profile

Biography

Louise Winteringham leads the Translational Cancer Research Program at the Perkins. Shas an extensive background in immunology and haematology focusing on the molecular and cellular biology of cancer, in particular haematological cancers. She completed her MSc in the Department of Clinical Immunology at Royal Perth Hospital investigating the impact of non-coding regions within the Major Histocompatibility Complex. Following three years working at St Bartholomew's Hospital in London, Louise was awarded the Richard Walter Gibbon Fellowship from the Faculty of Medicine, Dentistry and Health Sciences at UWA to undertake her PhD so she returned to Perth where she joined the Leukemia Laboratory at WAIMR, headed by Professor Peter Klinken. Louise continued her work in cancer research focusing on the biochemical and cellular mechanisms that drive oncogenesis. She has identified several novel genes associated with the development and progression of cancer. In 2017 she initiated the Translational Cancer Research Program at The Perkins, developing collaborations with pathologists and surgeons to provide a co-ordinated approach to quickly move laboratory discoveries into cancer treatments. As part of this program, she has established pre-clinical models able to accurately evaluate new cancer treatments that modulate our own immune systems to fight cancer. These models are currently being used to develop precision oncology medicine in combination with several omics technologies.

Funding overview

2018-2023 CI A Forrest, 41 AIs including L Winteringham. The CRT Collaborative Cancer Research Grant: Enabling advanced single cell cancer genomics in Western Australia. Requested AUD 6.5M.


2013–2015 Development of a Murine Cell Model of Diamond Blackfan Anaemia
Klinken, P. & Winteringham, L. Captain Courageous Foundation AUD 259,927

2013-2015 Leukemia transcriptomics. Winteringham, L., Klinlen, S.P. McCusker Foundation AUD 600,000

2015 Illumina NeoPrep Library System. Morahan, G., Winteringham, L., Forrest, A., Lister, R., Heng, J., Fox, A. National Health & Medical Research Council NHMRC AUD 39,136

2014 Targeting Acute Myeloid Leukemia with micro RNAs
LWinteringham, L., Klinken, S.P. Rachael Doherty Foundation AUD 92,000

2010-2012 Characterization of Haemopoietic Lineage Determining Genes. Klinken, P, Bond, C., Winteringham, L., National Health & Medical Research Council NHMRC AUD 608,500

Keywords

  • Biotechnology
  • Health
  • Drug Discovery
  • Medicine and Pharma
  • Diagnostics
  • Cancer
  • Novel cancer genes
  • Red blood cells
  • Cancer - translation
  • Personalised medicine
  • Humanised mice
  • Pre-clinical models
  • Leukemia

Fingerprint Dive into the research topics where Louise Winteringham is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
Myeloid Leukemia Medicine & Life Sciences
Erythropoietin Medicine & Life Sciences
Heterogeneous-Nuclear Ribonucleoprotein U Medicine & Life Sciences
Erythroid Cells Medicine & Life Sciences
Transcription Engineering & Materials Science
Genes Medicine & Life Sciences
Switches Chemical Compounds
Switch Genes Medicine & Life Sciences

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Research Output 1998 2018

  • 3205 Citations
  • 21 h-Index
  • 33 Article
  • 3 Conference paper
  • 1 Doctoral Thesis
203 Downloads (Pure)

Functional significance of TRIM35 In haematopoietic and hepatic homeostasis

Van Vuuren, J. H., 2018, (Unpublished)

Research output: ThesisDoctoral Thesis

File
Liver Neoplasms
Homeostasis
Inflammation
Ubiquitin-Protein Ligases
Liver
78 Citations (Scopus)

An integrated expression atlas of miRNAs and their promoters in human and mouse

de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Astrom, G., Babina, M., Bertin, N., Burroughs, A. M., Carlisle, A. J., Daub, C. O., Detmar, M., Deviatiiarov, R., Fort, A., Gebhard, C., Goldowitz, D., Guhl, S., Ha, T. J., Harshbarger, J. & 50 othersHasegawa, A., Hashimoto, K., Herlyn, M., Heutink, P., Hitchens, K. J., Hon, C. C., Huang, E., Ishizu, Y., Kai, C., Kasukawa, T., Klinken, P., Lassmann, T., Lecellier, C-H., Lee, W., Lizio, M., Makeev, V., Mathelier, A., Medvedeva, Y. A., Mejhert, N., Mungall, C. J., Noma, S., Ohshima, M., Okada-Hatakeyama, M., Persson, H., Rizzu, P., Roudnicky, F., Saetrom, P., Sato, H., Severin, J., Shin, J. W., Swoboda, R. K., Tarui, H., Toyoda, H., Vitting-Seerup, K., Winteringham, L., Yamaguchi, Y., Yasuzawa, K., Yoneda, M., Yumoto, N., Zabierowski, S., Zhang, P. G., Wells, C. A., Summers, K. M., Kawaji, H., Sandelin, A., Rehli, M., Hayashizaki, Y., Carninci, P., Forrest, A. R. R. & de Hoon, M. J. L., Sep 2017, In : Nature Biotechnology. 35, 9, p. 872–878

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

FANTOM5 CAGE profiles of human and mouse samples

Noguchi, S., Arakawa, T., Fukuda, S., Furuno, M., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Kaida, K., Kaiho, A., Kanamori-Katayama, M., Kawashima, T., Kojima, M., Kubosaki, A., Manabe, R. I., Murata, M., Nagao-Sato, S., Nakazato, K., Ninomiya, N., Nishiyori-Sueki, H., Noma, S. & 158 othersSaijyo, E., Saka, A., Sakai, M., Simon, C., Suzuki, N., Tagami, M., Watanabe, S., Yoshida, S., Arner, P., Axton, R. A., Babina, M., Kenneth Baillie, J., Barnett, T. C., Beckhouse, A. G., Blumenthal, A., Bodega, B., Bonetti, A., Briggs, J., Brombacher, F., Carlisle, A. J., Clevers, H. C., Davis, C. A., Detmar, M., Dohi, T., Edge, B. A. S., Edinger, M., Ehrlund, A., Ekwall, K., Endoh, M., Enomoto, H., Eslami, A., Fagiolini, M., Fairbairn, L., Farach-Carson, M. C., Faulkner, G. J., Ferrai, C., Fisher, M. E., Forrester, L. M., Fujita, R., Furusawa, J. I., Geijtenbeek, T. B., Gingeras, T., Goldowitz, D., Guhl, S., Guler, R., Gustincich, S., Ha, T. J., Hamaguchi, M., Hara, M., Hasegawa, Y., Herlyn, M., Heutink, P., Hitchens, K. J., Hume, D. A., Ikawa, T., Ishizu, Y., Kai, C., Kawamoto, H., Kawamura, Y. I., Kempfle, J. S., Kenna, T. J., Kere, J., Khachigian, L. M., Kitamura, T., Klein, S., Peter Klinken, S., Knox, A. J., Kojima, S., Koseki, H., Koyasu, S., Lee, W., Lennartsson, A., MacKay-Sim, A., Mejhert, N., Mizuno, Y., Morikawa, H., Morimoto, M., Moro, K., Morris, K. J., Motohashi, H., Mummery, C. L., Nakachi, Y., Nakahara, F., Nakamura, T., Nakamura, Y., Nozaki, T., Ogishima, S., Ohkura, N., Ohno, H., Ohshima, M., Okada-Hatakeyama, M., Okazaki, Y., Orlando, V., Ovchinnikov, D. A., Passier, R., Patrikakis, M., Pombo, A., Pradhan-Bhatt, S., Qin, X. Y., Rehli, M., Rizzu, P., Roy, S., Sajantila, A., Sakaguchi, S., Sato, H., Satoh, H., Savvi, S., Saxena, A., Schmidl, C., Schneider, C., Schulze-Tanzil, G. G., Schwegmann, A., Sheng, G., Shin, J. W., Sugiyama, D., Sugiyama, T., Summers, K. M., Takahashi, N., Takai, J., Tanaka, H., Tatsukawa, H., Tomoiu, A., Toyoda, H., Wetering, M., Berg, L. M. V. D., Verardo, R., Vijayan, DI., Wells, C. A., Winteringham, L. N., Wolvetang, E., Yamaguchi, Y., Yamamoto, M., Yanagi-Mizuochi, C., Yoneda, M., Yonekura, Y., Zhang, P. G., Zucchelli, S., Abugessaisa, I., Arner, E., Harshbarger, J., Kondo, A., Lassmann, T., Lizio, M., Sahin, S., Sengstag, T., Severin, J., Shimoji, H., Suzuki, M., Suzuki, H., Kawai, J., Kondo, N., Itoh, M., Daub, C. O., Kasukawa, T., Kawaji, H., Carninci, P., Forrest, A. R. R. & Hayashizaki, Y., 29 Aug 2017, In : Scientific Data. 4, 170112.

Research output: Contribution to journalArticle

Open Access
Gene Expression Profile
Gene expression
Mouse
Transcription
Cell
29 Citations (Scopus)

Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium

Yu, N. Y-L., Hallström, B. M., Fagerberg, L., Ponten, F., Kawaji, H., Carninci, P., Forrest, A., Hayashizaki, Y., Uhlén, M., Daub, C. O., Alam, I., Albanese, D., Altschuler, G., Andersson, R., Arakawa, T., Archer, J., Arner, E., Arner, P., Babina, M., Baillie, K. & 244 othersBajic, V., Baker, S., Balic, A., Balwierz, P., Beckhouse, A., Bertin, N., Blake, J. A., Blumenthal, A., Bodega, B., Bonetti, A., Briggs, J., Brombacher, F., Burroughs, M., Califano, A., Cannistraci, C., Carbajo, D., Chen, Y., Chierici, M., Ciani, Y., Clevers, H., Dalla, E., Davis, C., De Hoon, M., De Lima Morais, D., Detmar, M., Diehl, A., Dimont, E., Dohi, T., Drabros, F., Edge, A., Edinger, M., Ekwall, K., Endoh, M., Enomoto, H., Fagiolini, M., Fairbairn, L., Fang, H., Farach-Carson, M. C., Faulkner, G., Favorov, A., Fisher, M., Francescatto, M., Freeman, T., Frith, M., Fujita, R., Fukuda, S., Furlanello, C., Furuno, M., Furusawa, J-I., Geijtenbeek, T. B. H., Gibson, A., Gingeras, T., Goldowitz, D., Gough, J., Guhl, S., Guler, R., Gustincich, S., Ha, T., Haberle, V., Hamaguchi, M., Hara, M., Harbers, M., Harshbarger, J., Hasegawa, A., Hasegawa, Y., Hashimoto, T., Herlyn, M., Heutink, P., Hide, W., Hitchens, K., Ho Sui, S., Hofmann, O., Hoof, I., Hori, F., Hume, D., Huminiecki, L., Ilda, K., Ikawa, T., Ishizu, Y., Itoh, M., Jankovic, B., Jia, H., Jorgensen, M., Joshi, A., Jurman, G., Kaczkowski, B., Kai, C., Kaida, K., Kaiho, A., Kajiyama, K., Kanamori-Katayama, M., Kasianov, A., Kasukawa, T., Katayama, S., Kato, S., Kawaguchi, S., Kawai, J., Kawamoto, H., Kawamura, Y., Kwashima, T., Kempfle, J., Kenna, T., Kere, J., Khachigian, L., Kitamura, T., Klinken, P., Knox, A., Kojima, M., Kojima, S., Kondo, N., Koseki, H., Koyasu, S., Krampitz, S., Kubosaki, A., Kulalovskiy, I., Kwon, A. T. J., Laros, J., Lassmann, T., Lenhard, B., Lennartsson, A., Li, K., Lilje, B., Lipovich, L., Lizio, M., Mackay-Sim, A., Makeev, V., Manabe, R., Mar, J., Marchand, B., Mathelier, A., Medvedeva, Y., Meehan, T. F., Mejhert, N., Meynert, A., Mizuno, Y., Morikawa, H., Morimoto, M., Moro, K., Motakis, E., Motohashi, H., Mummery, C., Mungall, C. J., Murata, M., Nagao, S., Nakachi, Y., Nakahara, F., Nakamura, Y., Nakazato, K., Ninomiya, N., Nishiyori, H., Noma, S., Nozaki, T., Ogishima, S., Ohkura, N., Ohmiya, H., Ohno, H., Ohshima, M., Okada-Hatakeyama, M., Okazaki, Y., Orlando, V., Ovchinnikov, D., Pain, A., Passier, R., Persson, H., Piazza, S., Plessy, C., Pradhan-Bhatt, S., Prendergast, J., Rackham, O., Ramilowski, J., Rashid, M., Ravasi, T., Rehli, M., Rizzu, P., Roncador, M., Roy, S., Rye, M., Saijyo, E., Sajantila, A., Saka, A., Sakaguchi, S., Sakai, M., Sandelin, A., Sato, H., Satoh, H., Savvi, S., Saxena, A., Schaefer, U., Schmeier, S., Schmidl, C., Schneider, C., Schultes, E. A., Schulze-Tanzil, G., Schwegmann, A., Semple, C., Sengstag, T., Severin, J., Sheng, G., Shimoji, H., Shimoni, Y., Shin, J., Simon, C., Sugiyama, D., Sugiyama, T., Summers, K., Suzuki, H., Suzuki, M., Suzuki, N., Swoboda, R., T Hoen, P., Tagami, M., Takahashi, N., Takai, J., Tanaka, H., Tatsukawa, H., Tatum, Z., Taylor, M., Thompson, M., Toyoda, H., Toyoda, T., Valen, E., Van De Wetering, M., Van Den Berg, L., Van Nimwegen, E., Verardo, R., Vijayan, D., Vitezic, M., Vorontzov, I., Wasserman, W., Watanabe, S., Wells, C., Winteringham, L., Wolvetang, E., Wood, E. J., Yamaguchi, Y., Yamamoto, M., Yoneda, M., Yonekura, Y., Yoshida, S., Young, R., Zabierowski, S. E., Zhang, P., Zhao, X. & Zucchelli, S., 2015, In : Nucleic Acids Research. 43, p. 6787-6798

Research output: Contribution to journalArticle

Open Access
208 Citations (Scopus)

Gateways to the FANTOM5 promoter level mammalian expression atlas

Lizio, M., Harshbarger, J., Shimoji, H., Severin, J., Kasukawa, T., Sahin, S., Abugessaisa, I., Fukuda, S., Hori, F., Ishikawa-Kato, S., Mungall, C. J., Arner, E., Baillie, J. K., Bertin, N., Bono, H., De Hoon, M., Diehl, A. D., Dimont, E., Freeman, T. C., Fujieda, K. & 249 othersHide, W., Kaliyaperumal, R., Katayama, T., Lassmann, T., Meehan, T. F., Nishikata, K., Ono, H., Rehli, M., Sandelin, A., Schultes, E. A., T Hoen, P. A. C., Tatum, Z., Thompson, M., Toyoda, T., Wright, D. W., Daub, C. O., Itoh, M., Carninci, P., Hayashizaki, Y., Forrest, A., Kawaji, H., Alam, I., Albanese, D., Altschuler, G., Andersson, R., Arakawa, T., Archer, J., Arner, P., Babina, M., Bajic, V., Baker, S., Balic, A., Balwierz, P., Beckhouse, A., Blake, J. A., Blumenthal, A., Bodega, B., Bonetti, A., Briggs, J., Brombacher, F., Burroughs, M., Califano, A., Cannistraci, C., Carbajo, D., Chen, Y., Chierici, M., Ciani, Y., Clevers, H., Dalla, E., Davis, C., De Lima Morais, D., Detmar, M., Dohi, T., Drabros, F., Edge, A., Edinger, M., Ekwall, K., Endoh, M., Enomoto, H., Fagiolini, M., Fairbairn, L., Fang, H., Farach-Carson, M. C., Faulkner, G., Favorov, A., Fisher, M., Francescatto, M., Frith, M., Fujita, R., Furlanello, C., Furuno, M., Furusawa, J-I., Geijtenbeek, T. B. H., Gibson, A., Gingeras, T., Goldowitz, D., Gough, J., Guhl, S., Guler, R., Gustincich, S., Ha, T., Haberle, V., Hamaguchi, M., Hara, M., Harbers, M., Hasegawa, A., Hasegawa, Y., Hashimoto, T., Herlyn, M., Heutink, P., Hitchens, K., Ho Sui, S., Hofmann, O., Hoof, I., Hume, D., Huminiecki, L., Ilda, K., Ikawa, T., Ishizu, Y., Jankovic, B., Jia, H., Jorgensen, M., Joshi, A., Jurman, G., Kaczkowski, B., Kai, C., Kaida, K., Kaiho, A., Kajiyama, K., Kanamori-Katayama, M., Kasianov, A., Katayama, S., Kawaguchi, S., Kawai, J., Kawamoto, H., Kawamura, Y., Kawashima, T., Kempfle, J., Kenna, T., Kere, J., Khachigian, L., Kitamura, T., Klinken, P., Knox, A., Kojima, M., Kojima, S., Kondo, N., Koseki, H., Koyasu, S., Krampitz, S., Kubosaki, A., Kulakovskiy, I., Kwon, A. T. J., Laros, J., Lenhard, B., Lennartsson, A., Li, K., Lilje, B., Lipovich, L., Mackay-Sim, A., Makeev, V., Manabe, R., Mar, J., Marchand, B., Mathelier, A., Medvedeva, Y., Mejhert, N., Meynert, A., Mizuno, Y., Morikawa, H., Morimoto, M., Moro, K., Motakis, E., Motohashi, H., Mummery, C., Murata, M., Nagao, S., Nakachi, Y., Nakahara, F., Nakamura, T., Nakamura, Y., Nakazato, K., Ninomiya, N., Nishiyori, H., Noma, S., Nozaki, T., Ogishima, S., Ohkura, N., Ohmiya, H., Ohno, H., Ohshima, M., Okada-Hatakeyama, M., Okzaki, Y., Orlando, V., Ovchinnokov, D., Pain, A., Passier, R., Persson, H., Piazza, S., Plessy, C., Pradhan-Bhatt, S., Prendergast, J., Rackham, O., Ramilowski, J., Rashid, M., Ravasi, T., Rizzu, P., Roncador, M., Roy, S., Rye, M., Saijyo, E., Sajantila, A., Saka, A., Sakaguchi, S., Sakai, M., Sato, H., Satoh, H., Savvi, S., Saxena, A., Schaefer, U., Schmeier, S., Schmidl, C., Schneider, C., Schulze-Tanzil, G., Schwegmann, A., Semple, C., Sengstag, T., Sheng, G., Shimoni, Y., Shin, J., Simon, C., Sugiyama, D., Sugiyama, T., Summers, K., Suzuki, H., Suzuki, M., Suzuki, N., Swoboda, R., Tagami, M., Takahashi, N., Takai, J., Tanaka, H., Tatsukawa, H., Taylor, M., Toyoda, H., Valen, E., Van De Wetering, M., Van Den Berg, L., Van Nimwegen, E., Verardo, R., Vijayan, D., Vitezic, M., Vorontzov, I., Wasserman, W., Watanabe, S., Wells, C., Winteringham, L., Wolvetang, E., Wood, E. J., Yamaguchi, Y., Yamamoto, M., Yoneda, M., Yonekura, Y., Yoshida, S., Young, R., Zabierowski, S. E., Zhang, P., Zhao, X. & Zucchelli, S., 2015, In : Genome Biology. 16, p. 1-14

Research output: Contribution to journalArticle

Open Access
Atlases
atlas
Transcription Factors
promoter regions
Cell Line

Projects 2003 2015