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Liz Johnstone

Dr

  • The University of Western Australia (M519), 35 Stirling Highway,

    6009 Perth

    Australia

  • 133 Citations
  • 4 h-Index
20122019
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Personal profile

Biography

Elizabeth Johnstone obtained her PhD in Pharmacology from the University of Western Australia. She is currently based at the Harry Perkins Institute of Medical Research (Western Australia) where she studies the molecular pharmacology of G protein-coupled receptors in the laboratory of Associate Professor Kevin Pfleger. In addition to her post-doctoral research, she is also the Senior Project Officer with the Accelerating Australia program.

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  • 11 Similar Profiles
Energy Transfer Medicine & Life Sciences
Bioluminescence Chemical Compounds
G-Protein-Coupled Receptors Chemical Compounds
Energy transfer Chemical Compounds
Transcriptional Activation Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
CCR Receptors Medicine & Life Sciences
Angiotensin Type 1 Receptor Medicine & Life Sciences

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Research Output 2012 2019

  • 133 Citations
  • 4 h-Index
  • 5 Article
  • 1 Chapter
  • 1 Review article
  • 1 Doctoral Thesis
2 Citations (Scopus)

Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis

Pickering, R., Tikellis, C., Rosado, C., Tsorotes, D., Dimitrropoulos, A., Smith, M., Huet, O., Seeber, R., Abhayawardana, R., Johnstone, E., Golledge, J., Wang, Y., Jandeleit-Dahm, K., Cooper, M., Pfleger, K. & Thomas, M. C., 2 Jan 2019, In : The Journal of clinical investigation. 129, 1, p. 406-421 CI99987.

Research output: Contribution to journal › Article

Open Access
Angiotensins
Transcriptional Activation
Atherosclerosis
Inflammation
Angiotensin II
1 Citation (Scopus)
60 Downloads (Pure)

BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes

O'Brien, S. L., Johnstone, E. K. M., Devost, D., Conroy, J., Reichelt, M. E., Purdue, B. W., Ayoub, M. A., Kawai, T., Inoue, A., Eguchi, S., Hébert, T. E., Pfleger, K. D. G. & Thomas, W. G., 1 Dec 2018, In : Biochemical Pharmacology. 158, p. 232-242 11 p.

Research output: Contribution to journal › Article

Open Access
File
Gq-G11 GTP-Binding Protein alpha Subunits
Bioluminescence
Energy Transfer
Epidermal Growth Factor Receptor
Energy transfer
16 Citations (Scopus)

Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time

White, C. W., Vanyai, H. K., See, H. B., Johnstone, E. K. M. & Pfleger, K. D. G., 9 Jun 2017, In : Scientific Reports. 7, 1, 3187.

Research output: Contribution to journal › Article

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Energy Transfer
Genome
G-Protein-Coupled Receptors
Proteins

Biophysical insights into the molecular pharmacology of angiotensin II receptor heteromers

Johnstone, E., 2016, (Unpublished)

Research output: Thesis › Doctoral Thesis

File
Angiotensin Receptors
G-Protein-Coupled Receptors
Bioluminescence
Peptide Hormones
Angiotensin II
82 Citations (Scopus)

Application of BRET to monitor ligand binding to GPCRs

Stoddart, L. A., Johnstone, E., Wheal, A. J., Goulding, J., Robers, M. B., Machleidt, T., Wood, K. V., Hill, S. & Pfleger, K., Jul 2015, In : Nature Methods. 12, 7, p. 661-663 3 p.

Research output: Contribution to journal › Article

Open Access
Bioluminescence
Energy Transfer
G-Protein-Coupled Receptors
Energy transfer
Luminescent Proteins