Research Output per year
Personal profile
Biography
Elizabeth Johnstone obtained her PhD in Pharmacology from the University of Western Australia. She is currently based at the Harry Perkins Institute of Medical Research (Western Australia) where she studies the molecular pharmacology of G protein-coupled receptors in the laboratory of Associate Professor Kevin Pfleger. In addition to her post-doctoral research, she is also the Senior Project Officer with the Accelerating Australia program.
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Energy Transfer
Medicine & Life Sciences
Bioluminescence
Chemical Compounds
G-Protein-Coupled Receptors
Chemical Compounds
Energy transfer
Chemical Compounds
Transcriptional Activation
Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats
Medicine & Life Sciences
CCR Receptors
Medicine & Life Sciences
Angiotensin Type 1 Receptor
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2012 2019
Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis
Pickering, R., Tikellis, C., Rosado, C., Tsorotes, D., Dimitrropoulos, A., Smith, M., Huet, O., Seeber, R., Abhayawardana, R., Johnstone, E., Golledge, J., Wang, Y., Jandeleit-Dahm, K., Cooper, M., Pfleger, K. & Thomas, M. C., 2 Jan 2019, In : The Journal of clinical investigation. 129, 1, p. 406-421 CI99987.Research output: Contribution to journal › Article
Open Access
Angiotensins
Transcriptional Activation
Atherosclerosis
Inflammation
Angiotensin II
1
Citation
(Scopus)
60
Downloads
(Pure)
BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes
O'Brien, S. L., Johnstone, E. K. M., Devost, D., Conroy, J., Reichelt, M. E., Purdue, B. W., Ayoub, M. A., Kawai, T., Inoue, A., Eguchi, S., Hébert, T. E., Pfleger, K. D. G. & Thomas, W. G., 1 Dec 2018, In : Biochemical Pharmacology. 158, p. 232-242 11 p.Research output: Contribution to journal › Article
Open Access
File
Gq-G11 GTP-Binding Protein alpha Subunits
Bioluminescence
Energy Transfer
Epidermal Growth Factor Receptor
Energy transfer
16
Citations
(Scopus)
Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time
White, C. W., Vanyai, H. K., See, H. B., Johnstone, E. K. M. & Pfleger, K. D. G., 9 Jun 2017, In : Scientific Reports. 7, 1, 3187.Research output: Contribution to journal › Article
Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Energy Transfer
Genome
G-Protein-Coupled Receptors
Proteins
Biophysical insights into the molecular pharmacology of angiotensin II receptor heteromers
Johnstone, E., 2016, (Unpublished)Research output: Thesis › Doctoral Thesis
File
Angiotensin Receptors
G-Protein-Coupled Receptors
Bioluminescence
Peptide Hormones
Angiotensin II
Application of BRET to monitor ligand binding to GPCRs
Stoddart, L. A., Johnstone, E., Wheal, A. J., Goulding, J., Robers, M. B., Machleidt, T., Wood, K. V., Hill, S. & Pfleger, K., Jul 2015, In : Nature Methods. 12, 7, p. 661-663 3 p.Research output: Contribution to journal › Article
Open Access
Bioluminescence
Energy Transfer
G-Protein-Coupled Receptors
Energy transfer
Luminescent Proteins