Livia Hool

Professor, BSc PhD Macq., Professor

  • The University of Western Australia (M311), 35 Stirling Highway, Room 1.96, Physiology Building, Perth campus

    6009 Perth

    Australia

If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

* Gaston Bauer Cardiovascular Research Fellow, Cellular Electrophysiology Laboratory, Royal North Shore Hospital, Sydney 1991-1995
* American Heart Association Postdoctoral Fellow, Case Western Reserve University Cleveland Ohio, USA 1995-1997
* NHMRC Peter Doherty Fellow (Established the Cardiovascular Electrophysiology Laboratory) Physiology, The University of Western Australia 1998-2002
* NHMRC Career Development Award Fellow 2004 –2009
* ARC Future Fellow and Honorary NHMRC Senior Research Fellow 2011 - 2014
* NHMRC Senior Research Fellow 2015-16

NHMRC Senior Research Fellowship 2017-21

Funding overview

NHMRC Project Grant 2006-2008
NHMRC Project Grant 2009-2011
NHMRC Project Grant 2010-2012
NHMRC Project Grant 2011-2013
NHMRC Project Grant 2013-2015
NHMRC Project Grant 2014-2016

NHMRC Project Grant 2016-19

NHMRC Project Grant 2018-21

NHMRC National Heart Foundation Biomedical Scholarship and Research Fellowship
ARC Future Fellowship

Current projects

PhD Students

- Mr Ashay Shah (Co-supervised with Assoc Prof Swaminathan Iyer)

- Mr Ian Chin (Co-supervised with Assoc Prof Yu Suk Choi)
- Dr Warren Pavey (Co-supervised with Dr KM Ho)
- Ms Laetitia Hughes (Co-supervised with Professor Aleksandra Filipovska)

-Ms Jessica Baker (Co-supervised with Professor Aleksandra Filipovska)


Postdoctoral staff
Dr Helena Viola
Dr Henrietta Cserne Szappanos
Dr Naaz Andharia

Research Assistant

Ms Tanya Solomon

Honours students/BPhil students
Mr Ege Eroglu

Potential Student Projects

- Improving efficacy of AID peptide in treatment of familial hypertrophic cardiomyopathy
- Elucidating structure/function of the L-type calcium channel alpha (Cav1.2) subunit


Collaborators

-Professor Yoram Rudy, Washington University, St. Louis, Missouri USA
-Professor Christopher Semsarian, Centenary Institute Sydney

-Dr Adam Hill VCCRI
-Professors Kricket Seidman and Jon Seidman, Harvard University, USA
-Professor Swaminatha Iyer, Chemistry and Biochemistry, UWA
-Professor Nigel Laing, The Harry Perkins Institute for Medical Research
-Professor Aleksandra Filipovska, The Harry Perkins Institute for Medical Research
-Assoc Professor Marco Casarotto ANU
-Assoc Prof Evan Ingley, The Harry Perkins Institute for Medical Research
- Professor Ken Roos, University of California Los Angeles
- Professor Filip van Petegem University of British Columbia

Teaching overview

PHYL3300 Mammalian Cell Biology
PHYL3350 Physiological Control Mechanisms
PHYL3002 Physiology of Cardiovascular and Respiratory Systems

Research

1. Regulation of L-type Ca2+ channel function under pathological conditions such as hypoxia and oxidative stress
2. Regulation of the L-type Ca2+ channel by adrenergic receptor stimulation during hypoxia and oxidative stress
3. Regulation of mitochondrial function by the L-type calcium channel and the role of the cytoskeleton
4. Targeting the L-type Ca2+ channel to prevent the development of cardiomyopathy
5. Use of nanoparticle technology to improve efficacy of therapy
6. Use of CRISPR-like technology to prevent hypertrophy
7. Improving efficacy of uptake of oligomers to treat Duchenne Muscular Dystrophy cardiomyopathy

Research expertise keywords

  • Cardiac electrophysiology
  • Membrane transport
  • Cardiovascular physiology
  • Calcium transport
  • Patch-clamp technology
  • Echocardiography
  • Cardiac physiology

Fingerprint

Dive into the research topics where Livia Hool is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 12 Similar Profiles

Network

Recent external collaboration on country level. Dive into details by clicking on the dots or
If you made any changes in Pure these will be visible here soon.