• The University of Western Australia (M517), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1477 Citations
  • 22 h-Index
20052020

Research output per year

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Research Output

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Article
2019

The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations

Hart, N. S., Mountford, J. K., Voigt, V., Fuller-Carter, P., Barth, M., Nerbonne, J. M., Hunt, D. M. & Carvalho, L. S., Feb 2019, In : eNeuro. 6, 1, 13 p., UNSP ENEURO.0032-19.2019.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo

Carvalho, L. S., Xiao, R., Wassmer, S. J., Langsdorf, A., Zinn, E., Pacouret, S., Shah, S., Comander, J. I., Kim, L. A., Lim, L. & Vandenberghe, L. H., Jul 2018, In : Human Gene Therapy. 29, 7, p. 771-784 14 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2017

Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting

Carvalho, L. S., Turunen, H. T., Wassmer, S. J., Luna-Velez, M. V., Xiao, R., Bennett, J. & Vandenberghe, L. H., 8 Sep 2017, In : Frontiers in Neuroscience. 11, 8 p., 503.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

Wassmer, S. J., Carvalho, L. S., György, B., Vandenberghe, L. H. & Maguire, C. A., 31 Mar 2017, In : Scientific Reports. 7, 45329.

Research output: Contribution to journalArticle

Open Access
26 Citations (Scopus)
2015

Annexin-A1 restricts Th17 cells and attenuates the severity of autoimmune disease

Yazid, S., Gardner, P. J., Carvalho, L., Chu, C. J., Flower, R. J., Solito, E., Lee, R. W. J., Ali, R. R. & Dick, A. D., 1 Apr 2015, In : Journal of Autoimmunity. 58, p. 1-11 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Cd59a deficiency in mice leads to preferential innate immune activation in the retinal pigment epithelium-choroid with age

Herrmann, P., Cowing, J. A., Cristante, E., Liyanage, S. E., Ribeiro, J., Duran, Y., Abelleira Hervas, L., Carvalho, L. S., Bainbridge, J. W. B., Luhmann, U. F. O. & Ali, R. R., Sep 2015, In : Neurobiology of Aging. 36, 9, p. 2637-2648 12 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179

Nishiguchi, K. M., Carvalho, L. S., Rizzi, M., Powell, K., Holthaus, S-M. K., Azam, S. A., Duran, Y., Ribeiro, J., Luhmann, U. F. O., Bainbridge, J. W. B., Smith, A. J. & Ali, R. R., Feb 2015, In : Nature Communications. 6, 7006.

Research output: Contribution to journalArticle

Open Access
41 Citations (Scopus)

In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector

Zinn, E., Pacouret, S., Khaychuk, V., Turunen, H. T., Carvalho, L. S., Andres-Mateos, E., Shah, S., Shelke, R., Maurer, A. C., Plovie, E., Xiao, R. & Vandenberghe, L. H., 11 Aug 2015, In : Cell Reports. 12, 6, p. 1056-1068 13 p.

Research output: Contribution to journalArticle

Open Access
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113 Citations (Scopus)
102 Downloads (Pure)

Promising and delivering gene therapies for vision loss

Carvalho, L. S. & Vandenberghe, L. H., Jun 2015, In : Vision Research. 111, Part B, p. 124-133 10 p.

Research output: Contribution to journalArticle

Open Access
25 Citations (Scopus)

The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors

Luhmann, U. F. O., Carvalho, L. S., Holthaus, S-M. K., Cowing, J. A., Greenaway, S., Chu, C. J., Herrmann, P., Smith, A. J., Munro, P. M. G., Potter, P., Bainbridge, J. W. B. & Ali, R. R., 1 Jan 2015, In : Human Molecular Genetics. 24, 1, p. 128-141 14 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)
2013

Assessment and in vivo scoring of murine experimental autoimmune uveoretinitis using optical coherence tomography

Chu, C. J., Herrmann, P., Carvalho, L. S., Liyanage, S. E., Bainbridge, J. W. B., Ali, R. R., Dick, A. D. & Luhmann, U. F. O., 2013, In : PLoS One. 8, 5, p. e63002

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)

Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration

Luhmann, U. F. O., Carvalho, L. S., Robbie, S. J., Cowing, J. A., Duran, Y., Munro, P. M. G., Bainbridge, J. W. B. & Ali, R. R., Feb 2013, In : Experimental Eye Research. 107, p. 80-87 8 p.

Research output: Contribution to journalArticle

Open Access
32 Citations (Scopus)

How parrots see their colours: Novelty in the visual pigments of Platycercus elegans

Knott, B., Davies, W., dos Santos Carvalho, L., Berg, M. L., Buchanan, K. L., Bowmaker, J. K., Bennett, A. T. D. & Hunt, D., 2013, In : Journal of Experimental Biology. 216, 23, p. 4454-4461

Research output: Contribution to journalArticle

18 Citations (Scopus)

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

Gonzalez-Cordero, A., West, E. L., Pearson, R. A., Duran, Y., Carvalho, L. S., Chu, C. J., Naeem, A., Blackford, S. J. I., Georgiadis, A., Lakowski, J., Hubank, M., Smith, A. J., Bainbridge, J. W. B., Sowden, J. C. & Ali, R. R., Aug 2013, In : Nature Biotechnology. 31, 8, p. 741-747 7 p.

Research output: Contribution to journalArticle

228 Citations (Scopus)
2012

Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling

Luhmann, U. F. O., Lange, C. A., Robbie, S. J., Munro, P. M. G., Cowing, J. A., Armer, H. E. J., Luong, V., Carvalho, L. S., MacLaren, R. E., Fitzke, F. W., Bainbridge, J. W. B. & Ali, R. R., 2012, In : PLoS One. 7, 4, p. e35551

Research output: Contribution to journalArticle

Open Access
44 Citations (Scopus)
39 Citations (Scopus)
2011

Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy

Carvalho, L. S., Xu, J., Pearson, R. A., Smith, A. J., Bainbridge, J. W. B., Morris, L. M., Fliesler, S. J., Ding, X-Q. & Ali, R. R., 15 Aug 2011, In : Human Molecular Genetics. 20, 16, p. 3161-75 15 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Ultraviolet-sensitive vision in long-lived birds

dos Santos Carvalho, L., Knott, B., Berg, M. L., Bennett, A. T. D. & Hunt, D., 2011, In : Proceedings of the Royal Society B: Biological Sciences. 278, p. 107–114

Research output: Contribution to journalArticle

30 Citations (Scopus)
2009

Cone visual pigments in two species of South American marsupials

Hunt, D., Chan, J., dos Santos Carvalho, L., Hokoc, J., Ferguson, M., Arrese, C. & Beazley, L., 2009, In : Gene. 433, 1-2, p. 50-55

Research output: Contribution to journalArticle

23 Citations (Scopus)

Into the blue: Gene duplication and loss underlie color vision adaptations in a deep-sea chimaera, the elephant shark Callorhinchus milii

Davies, W. L., dos Santos Carvalho, L., Tay, B-H., Brenner, S., Hunt, D. & Venkatesh, B., 2009, In : Genome Research. 19, p. 415-426

Research output: Contribution to journalArticle

45 Citations (Scopus)

Shedding Light on Serpent Sight: The Visual Pigments of Henophidian snakes

Davies, W., Cowing, J. A., Bowmaker, J. K., dos Santos Carvalho, L., Gower, D. J. & Hunt, D., 2009, In : Journal of Neuroscience. 29, 23, p. 7519-7525

Research output: Contribution to journalArticle

42 Citations (Scopus)
2008

The influence of ontogeny and light environment on the expression of visual pigment opsins in the retina of the black bream, Acanthopagrus butcheri

Shand, J., Davies, W. L., Thomas, N., Balmer, L., Cowing, J. A., Pointer, M., Carvalho, L. S., Trezise, A. E. O., Collin, S., Beazley, L. & Hunt, D., 2008, In : The Journal of Experimental Biology. 211, 9, p. 1495-1503

Research output: Contribution to journalArticle

95 Citations (Scopus)
2007

Functional characterization, tuning, and regulation of visual pigment gene expression in an anadromous lamprey

Davies, W. L., Cowing, J. A., dos Santos Carvalho, L., Potter, I. C., Trezise, A. E. O., Hunt, D. & Collin, S., 2007, In : The FASEB Journal. 21, p. 2713-2724

Research output: Contribution to journalArticle

54 Citations (Scopus)

Spectral tuning of Shortwave-sensitive Visual Pigments in Vertebrates

Hunt, D., dos Santos Carvalho, L., Cowing, J. A., Parry, J. W. L., Wilkie, S. E., Davies, W. L. & Bowmaker, J. K., 2007, In : Photochemistry and Photobiology. 83, p. 303-310

Research output: Contribution to journalArticle

69 Citations (Scopus)

SPLICE: a technique for generating in vitro spliced coding sequences from genomic DNA

Davies, W. L., Carvalho, L. S. & Hunt, D. M., Dec 2007, In : BioTechniques. 43, 6, p. 785-789 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The molecular evolution of avian ultraviolet- and violet-sensitive visual pigments

dos Santos Carvalho, L., Cowing, J. A., Wilkie, S. E., Bowmaker, J. K. & Hunt, D., 2007, In : Molecular Biology and Evolution. 24, p. 1843-1852

Research output: Contribution to journalArticle

45 Citations (Scopus)

The visual pigments of a deep-sea teleost, the pearl eye Scopelarchus analis

Pointer, M. A., dos Santos Carvalho, L., Cowing, J. A., Bowmaker, J. K. & Hunt, D., 2007, In : Journal of Experimental Biology. 210, p. 2829-2835

Research output: Contribution to journalArticle

19 Citations (Scopus)

Visual pigments of the platypus: A novel route to mammalian colour vision

Davies, W., dos Santos Carvalho, L., Cowing, J. A., Beazley, L., Hunt, D. & Arrese, C. A., 2007, In : Current Biology. 17, 5, p. 161-163

Research output: Contribution to journalArticle

53 Citations (Scopus)
2005

Color vision in Leontopithecus chrysomelas: A behavioral study

Pessoa, D. M. A., Perini, E. S., Carvalho, L. S., Tomaz, C. & Pessoa, V. F., Feb 2005, In : International Journal of Primatology. 26, 1, p. 147-158 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)