• The University of Western Australia (M517), 35 Stirling Highway,

    6009 Perth


  • 1304 Citations
  • 20 h-Index
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Personal profile


My research interests have always been in the field of vision science and I have worked on developing and investigating gene therapy treatments for severe inherited retinal dystrophies along studies into understanding the cellular and molecular mechanisms behind age-related macular degeneration, uveitis, stem cells and AAV biology. My current focus is on creating research platforms in the area of retinal degeneration, gene therapy and cell death mechanisms.

Funding overview

ARC Discovery Early Career Research Award, Retina Australia

Current projects

1. Cone photoreceptor migration and cell death mechanisms during retinal degeneration
2. Voltage-gated potassium channels in inherited retinal dystrophy: disease mechanisms and treatment strategies


Retinal gene therapy, Inherited retinal degeneration, photoreceptor biology, cell death, retinal development

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Retina Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Retinal Pigments Medicine & Life Sciences
Retinal Degeneration Medicine & Life Sciences
Genes Medicine & Life Sciences
Color Vision Defects Medicine & Life Sciences
pigments Agriculture & Biology
Color Vision Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2019

The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations

Hart, N. S., Mountford, J. K., Voigt, V., Fuller-Carter, P., Barth, M., Nerbonne, J. M., Hunt, D. M. & Carvalho, L. S., Feb 2019, In : eNeuro. 6, 1

Research output: Contribution to journalArticle

Open Access
Voltage-Gated Potassium Channels
Retinal Diseases
Gene Knockout Techniques
Knockout Mice
6 Citations (Scopus)

Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo

Carvalho, L. S., Xiao, R., Wassmer, S. J., Langsdorf, A., Zinn, E., Pacouret, S., Shah, S., Comander, J. I., Kim, L. A., Lim, L. & Vandenberghe, L. H., Jul 2018, In : Human Gene Therapy. 29, 7, p. 771-784 14 p.

Research output: Contribution to journalArticle

Retinal Cone Photoreceptor Cells
Retinal Pigment Epithelium
4 Citations (Scopus)

Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting

Carvalho, L. S., Turunen, H. T., Wassmer, S. J., Luna-Velez, M. V., Xiao, R., Bennett, J. & Vandenberghe, L. H., 8 Sep 2017, In : Frontiers in Neuroscience. 11, 8 p., 503.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

Wassmer, S. J., Carvalho, L. S., György, B., Vandenberghe, L. H. & Maguire, C. A., 31 Mar 2017, In : Scientific Reports. 7, 45329.

Research output: Contribution to journalArticle

Open Access
Intravitreal Injections
Green Fluorescent Proteins
8 Citations (Scopus)

The genetic and evolutionary drives behind primate color vision

Carvalho, L. S., Pessoa, D. M. A., Mountford, J. K., Davies, W. I. L. & Hunt, D. M., 26 Apr 2017, In : Frontiers in Ecology and Evolution. 5, 34.

Research output: Contribution to journalReview article

Open Access
color vision

Projects 2016 2016