• The University of Western Australia (M517), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1401 Citations
  • 21 h-Index
20052020
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Personal profile

Biography

My research interests have always been in the field of vision science and I have worked on developing and investigating gene therapy treatments for severe inherited retinal dystrophies along studies into understanding the cellular and molecular mechanisms behind age-related macular degeneration, uveitis, stem cells and AAV biology. My current focus is on creating research platforms in the area of retinal degeneration, gene therapy and cell death mechanisms.

Funding overview

ARC Discovery Early Career Research Award, Retina Australia

Current projects

1. Cone photoreceptor migration and cell death mechanisms during retinal degeneration
2. Voltage-gated potassium channels in inherited retinal dystrophy: disease mechanisms and treatment strategies

Research

Retinal gene therapy, Inherited retinal degeneration, photoreceptor biology, cell death, retinal development

Fingerprint Dive into the research topics where Livia dos Santos Carvalho is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Retina Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Retinal Pigments Medicine & Life Sciences
Retinal Degeneration Medicine & Life Sciences
Genes Medicine & Life Sciences
Color Vision Defects Medicine & Life Sciences
pigments Agriculture & Biology
Color Vision Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2019

1 Citation (Scopus)

The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations

Hart, N. S., Mountford, J. K., Voigt, V., Fuller-Carter, P., Barth, M., Nerbonne, J. M., Hunt, D. M. & Carvalho, L. S., Feb 2019, In : eNeuro. 6, 1, 13 p., UNSP ENEURO.0032-19.2019.

Research output: Contribution to journalArticle

Open Access
Voltage-Gated Potassium Channels
Retinal Diseases
Gene Knockout Techniques
Knockout Mice
Mutation
9 Citations (Scopus)

Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo

Carvalho, L. S., Xiao, R., Wassmer, S. J., Langsdorf, A., Zinn, E., Pacouret, S., Shah, S., Comander, J. I., Kim, L. A., Lim, L. & Vandenberghe, L. H., Jul 2018, In : Human Gene Therapy. 29, 7, p. 771-784 14 p.

Research output: Contribution to journalArticle

Primates
Retinal Cone Photoreceptor Cells
Retina
Retinal Pigment Epithelium
Genes

Validation and comparison of Achromatopsia mouse lines expressing a fluorescent marker in cone photoreceptors

Carvalho, L. S., Voigt, V., Schuster, I., Fuller-Carter, P., Quesada, J. P., Vasiliou, S. & Hunt, D. M., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p.

Research output: Contribution to journalAbstract/Meeting Abstract

8 Citations (Scopus)

Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting

Carvalho, L. S., Turunen, H. T., Wassmer, S. J., Luna-Velez, M. V., Xiao, R., Bennett, J. & Vandenberghe, L. H., 8 Sep 2017, In : Frontiers in Neuroscience. 11, 8 p., 503.

Research output: Contribution to journalArticle

Open Access

Projects 2016 2020