Liisa Hirvonen

Dr, BSc PhD King's College London

  • The University of Western Australia (M519), 35 Stirling Highway,

    6009 Perth

    Australia

  • Source: Scopus
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Personal profile

Biography

I am an experimental physicist / biophysicist interested in all aspects of optical microscopy. I obtained my PhD in Physics in 2008 from King’s College London, UK, in developing the (at the time novel) Structured Illumination Microscopy (SIM) super-resolution technique. I then held several postdoctoral positions at the University of Melbourne, Australia, and King’s College London, UK, where I continued to develop novel super-resolution and time-resolved fluorescence microscopy methods, and gained extensive experience in a broad range of optical microscopy techniques (including multiphoton, TIRF, lightsheet and atomic force microscopy, various super-resolution methods and fluorescence lifetime imaging (FLIM)).

I joined the Centre for Microscopy, Characterisation and Analysis (CMCA) at UWA in 2019 as a lecturer and leader of the Optical Microscopy platform. I oversee all CMCA Optical Microscopy equipment and provide training and ongoing support to the users of the Optical Microscopy platform.

Research

My main research interests are: 

(1) Development of novel super-resolution methods with our STORM & SIM microscopes. New fast image collection methods will enable high-speed nanoscale 3D and live cell imaging, and have applications especially in cell biology to visualise the nanoscale structure and dynamics of intracellular structures.

(2) Development and application of time-resolved fluorescence imaging (e.g. FLIM) and analysis techniques for both biological and materials sciences.

(3) Development of high resolution Correlative Light and Electron Microscopy (CLEM) workflows in collaboration with CMCA’s Electron Microscopy platform.

Teaching overview

SCIE5516 - Materials Characterisation for Bioengineering Applications

Roles and responsibilities

Platform Leader - CMCA Optical Microscopy

WA State Rep - Light Microscopy Australia

Education/Academic qualification

Physics, PhD, King's College London

Jul 2005Dec 2008

Award Date: 1 Dec 2008

Physics with Computer Science, BSc, King's College London

Sep 2002Jun 2005

Award Date: 30 Jun 2005

Research expertise keywords

  • Optical Microscopy
  • Fluorescence microscopy
  • FLIM
  • Super-resolution
  • Photon counting
  • Cell imaging
  • Correlative microscopy
  • Cell biology
  • CLEM

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