Research output per year
Research output per year
Personal profile
Research
Dr Kirkham's research focus is on understanding the pathogenesis of bacterial respiratory infections and strategies to reduce the burden of disease, including development of improved vaccines. Current research areas include:
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
Research expertise keywords
- Otitis media
- Pneumococcal disease
- Vaccine development
- Meningitis
- Bacterial infections
- Microbiology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Evaluating the impact of the ‘Blow, Breathe, Cough’ health promotion intervention in resolving otitis media with effusion in children: An adaptive randomized-controlled trial protocol
Rich, J. R., Dymock, M., Seppanen, E. J., Montgomery, E., Cayley, T., Veselinović, T., Bernabei, G., Lester, A., Hannigan, A., Irvine, N., Gidgup, K., Ninyette, E., Bray, S., Tran, T. T., Swift, V. M., Edmunds, M., Strobel, N., McAullay, D., Marsh, J. & Tay, E. & 8 others, , Oct 2025, In: Contemporary Clinical Trials Communications. 47, 101531.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Citations (Scopus) -
Haemophilus influenzae remains the predominant otitis media pathogen in Australian children undergoing ventilation tube insertion in the PCV13 era
OMinWA Team, Seppanen, E., Clark, S., Herbert, H., Friedland, P., Richmond, P., Thornton, R. & Kirkham, L.-A., Apr 2025, In: Journal of Infection.. 90, 4, 106478.Research output: Contribution to journal › Article › peer-review
Open Access -
Minimising antibiotic use through prevention of childhood ear infections
Kirkham, L. A. S., Nov 2025, In: Microbiology Australia. 46, 4, p. 231-233 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
An infant mouse model of influenza-drivennontypeable Haemophilus influenzaecolonization and acute otitis media suitable for preclinical testing of novel therapies
Landwehr, K. R., Granland, C. M., Martinovich, K. M., Scott, N. M., Seppanen, E. J., Berry, L., Strickland, D., Fulurija, A., Richmond, P. C. & Kirkham, L. A. S., May 2024, In: Infection and Immunity. 92, 5, 13 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Clinical predictors of hypoxic pneumonia in children from the Eastern Highlands Province, Papua New Guinea: secondary analysis of two prospective observational studies
Britton, K. J., Pomat, W., Sapura, J., Kave, J., Nivio, B., Ford, R., Kirarock, W., Moore, H. C., Kirkham, L. A., Richmond, P. C., Chan, J., Lehmann, D., Russell, F. M. & Blyth, C. C., Apr 2024, In: The Lancet Regional Health - Western Pacific. 45, 10 p., 101052.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus)
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Clinical development of a nasal therapy to prevent otitis media and other respiratory infections
Kirkham, L.-A. (Investigator 01), Richmond, P. (Investigator 02), Fulurija, A. (Investigator 03), Thornton, R. (Investigator 04) & Cooper, M. (Investigator 05)
Stan Perron Charitable Foundation
21/10/25 → 28/02/29
Project: Research
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Replacement of laboratory sterilisation equipment for paediatric health and medical research and innovation.
Hales, B. (Investigator 01), Samuels, A. (Investigator 02), Kirkham, L.-A. (Investigator 03) & Endersby, R. (Investigator 04)
Department of Health (Western Australia)
25/06/25 → 25/06/28
Project: Research
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Blitz-OM: A single-dose anti-biofilm gel to effectively treat recurrent and chronic otitis media
Thornton, R. (Investigator 01), Kirkham, L.-A. (Investigator 02), Hughes, T. (Investigator 03), Richmond, P. (Investigator 04) & Clark, S. (Investigator 05)
NHMRC National Health and Medical Research Council
1/01/25 → 31/12/27
Project: Research
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Developing probiotics to prevent childhood pneumonia
Nicol, M. (Investigator 01), Kar Bahal, R. (Investigator 02), Garratt, L. (Investigator 03), Laucirica, D. (Investigator 04), Kicic, A. (Investigator 05), Pickering, J. (Investigator 06), Barnett, T. (Investigator 07), Chooi, H. (Investigator 08) & Kirkham, L.-A. (Investigator 09)
Department of Health (Western Australia)
1/01/24 → 31/12/26
Project: Research
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Advancing a Western Australian-led clinical trial to test the safety and tolerability of an anti-biofilm therapy in children with recurrent otitis media.
Thornton, R. (Investigator 01), Richmond, P. (Investigator 02), Kirkham, L.-A. (Investigator 03), Vijayasekaran, S. (Investigator 04), Brennan-Jones, C. (Investigator 05), Li, I. (Investigator 06), Kuthubutheen, J. (Investigator 07), Herbert, H. (Investigator 08) & Friedland, P. (Investigator 09)
Department of Health (Western Australia)
1/01/23 → 31/12/26
Project: Research