Lea-Ann Kirkham

Dr, PhD Glas.

Senior Research Fellow, Faculty of Health and Medical Sciences, Centre for Child Health Research

https://orcid.org/0000-0001-5421-8126

Emaillea-ann.kirkham@uwa.edu.au

The University of Western Australia (M561), 35 Stirling Highway,
6009 Perth
Australia

700 Citations
14 h-Index

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Personal profile

Research

Dr Kirkham's research focus is on understanding the pathogenesis of bacterial respiratory infections and strategies to reduce the burden of disease, including development of improved vaccines. Current research areas include:
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract

Keywords

Otitis media
Pneumococcal disease
Vaccine development
Meningitis
Bacterial infections
Microbiology

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12 Similar Profiles

Haemophilus influenzae Medicine & Life Sciences

Otitis Media Medicine & Life Sciences

otitis media Agriculture & Biology

Pneumococcal Vaccines Medicine & Life Sciences

Immunoglobulin G Medicine & Life Sciences

Haemophilus Medicine & Life Sciences

Conjugate Vaccines Medicine & Life Sciences

Middle Ear Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2019

700 Citations
14 h-Index
42 Article
2 Review article
1 Abstract/Meeting Abstract

2 Citations (Scopus)

Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

Bhuiyan, M. U., Blyth, C. C., West, R., Lang, J., Rahman, T., Granland, C., de Gier, C., Borland, M. L., Thornton, R. B., Kirkham, L-A. S., Martin, A., Richmond, P. C., Smith, D. W., Jaffe, A. & Snelling, T. L., 2 Apr 2019, In : BMC Pulmonary Medicine. 19, 1, 9 p., 71.

Research output: Contribution to journal › Article

Open Access

High concentrations of middle ear antimicrobial peptides and proteins and proinflammatory cytokines are associated with detection of middle ear pathogens in children with recurrent acute otitis media

Seppanen, E. J., Thornton, R. B., Corscadden, K. J., Granland, C. M., Hibbert, J., Fuery, A., Wiertsema, S. P., Vijayasekaran, S., Coates, H. L., Jacoby, P., Currie, A., Richmond, P. C. & Kirkham, L. A. S., 26 Dec 2019, In : PLoS One. 14, 12, e0227080.

Research output: Contribution to journal › Article

Open Access

antimicrobial proteins

otitis media

Otitis Media with Effusion

antimicrobial peptides

Otitis Media

1 Citation (Scopus)

Immunogenicity and immune memory after a pneumococcal polysaccharide vaccine booster in a high-risk population primed with 10-valent or 13-valent pneumococcal conjugate vaccine: A randomized controlled trial in Papua New Guinean children

van den Biggelaar, A. H. J., Pomat, W. S., Masiria, G., Wana, S., Nivio, B., Francis, J., Ford, R., Passey, M., Kirkham, L. A., Jacoby, P., Lehmann, D. & Richmond, P., 4 Feb 2019, In : Vaccines. 7, 1, 17.

Research output: Contribution to journal › Article

Open Access

Conjugate Vaccines

Pneumococcal Vaccines

Randomized Controlled Trials

Population

Pneumococcal Infections

2 Citations (Scopus)

PCV7- and PCV10-Vaccinated Otitis-Prone Children in New Zealand Have Similar Pneumococcal and Haemophilus influenzae Densities in Their Nasopharynx and Middle Ear

de Gier, C., Granland, C. M., Pickering, J. L., Walls, T., Bhuiyan, M., Mills, N., Richmond, P. C., Best, E. J., Thornton, R. B. & Kirkham, L-A. S., 31 Jan 2019, In : Vaccines. 7, 1, 14 p., 14.

Research output: Contribution to journal › Article

Open Access