Research output per year
Research output per year
Personal profile
Research
Dr Kirkham's research focus is on understanding the pathogenesis of bacterial respiratory infections and strategies to reduce the burden of disease, including development of improved vaccines. Current research areas include:
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research expertise keywords
- Otitis media
- Pneumococcal disease
- Vaccine development
- Meningitis
- Bacterial infections
- Microbiology
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An eight-plex immunoassay for Group A streptococcus serology and vaccine development
Whitcombe, A. L., Han, F., McAlister, S. M., Kirkham, L. A. S., Young, P. G., Ritchie, S. R., Atatoa Carr, P., Proft, T. & Moreland, N. J., Jan 2022, In: Journal of Immunological Methods. 500, 113194.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Australian Aboriginal Otitis-Prone Children Produce High-Quality Serum IgG to Putative Nontypeable Haemophilus influenzae Vaccine Antigens at Lower Titres Compared to Non-Aboriginal Children
Clark, S. L., Seppanen, E. J., Kirkham, L. A. S., Novotny, L. A., Bakaletz, L. O., Cripps, A. W., Corscadden, K., Coates, H., Vijayasekaran, S., Richmond, P. C. & Thornton, R. B., 7 Apr 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 767083.Research output: Contribution to journal › Article › peer-review
Open Access -
Evidence of maternal transfer of antigen-specific antibodies in serum and breast milk to infants at high-risk of S. pneumoniae and H. influenzae disease
Martinovich, K. M., Seppanen, E. J., Bleakley, A. S., Clark, S. L., Andrews, R. M., Richmond, P. C., Binks, M. J., Thornton, R. B. & Kirkham, L. A. S., 21 Sep 2022, In: Frontiers in Immunology. 13, 17 p., 1005344.Research output: Contribution to journal › Article › peer-review
Open Access -
Immunogenicity of a Third Scheduled Dose of Rotarix in Australian Indigenous Infants: A Phase IV, Double-blind, Randomized, Placebo-Controlled Clinical Trial
Middleton, B. F., Danchin, M., Jones, M. A., Leach, A. J., Cunliffe, N., Kirkwood, C. D., Carapetis, J., Gallagher, S., Kirkham, L. A., Granland, C., McNeal, M., Marsh, J. A., Waddington, C. S. & Snelling, T. L., 1 Nov 2022, In: The Journal of infectious diseases. 226, 9, p. 1537-1544 8 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Sleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies
Mateus, T., Seppanen, E. J., de Gier, C., Clark, S., Coates, H., Vijayasekaran, S., Prosser, K., Wiertsema, S. P., Fuery, A., Kirkham, L. A. S., Richmond, P. C. & Thornton, R. B., 28 Feb 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 831887.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
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Perron People L Kirkham Novel therapies to prevent ear infections in WA children
Stan Perron Charitable Foundation
1/01/22 → 31/12/26
Project: Research
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Merck Investigator Studies Program - A cross-sectional observational study on the aetiology of recurrent acute otitis media in Western Australia in the PCV13-era: the WALACE study (Western Australian Aetiology of Acute and Chronic Ear Disease)
Kirkham, L., Richmond, P., Herbert, H., Vijayasekaran, S., Sim, G., Kuthubutheen, J., Swift, V. & Brennan-Jones, C.
Merck, Sharp & Dohme Australia
23/09/21 → 23/09/23
Project: Research
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Round 8 - A bacterial therapy to prevent otitis media – preparing for first-in-human studies
Kirkham, L., Richmond, P., Fulurija, A., Seppanen, E. & Strickland, D.
Department of Health (Western Australia)
1/07/20 → 28/02/23
Project: Research
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MHRIF Round 22 - Lea-Ann Kirkham
Department of Health (Western Australia)
1/01/19 → 31/12/19
Project: Research