Research output per year
Research output per year
Personal profile
Research
Dr Kirkham's research focus is on understanding the pathogenesis of bacterial respiratory infections and strategies to reduce the burden of disease, including development of improved vaccines. Current research areas include:
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
Research expertise keywords
- Otitis media
- Pneumococcal disease
- Vaccine development
- Meningitis
- Bacterial infections
- Microbiology
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Differences in Pneumococcal and Haemophilus influenzae Natural Antibody Development in Papua New Guinean Children in the First Year of Life
the 10v13v PCV Trial Team, Martinovich, K. M., Rahman, T., de Gier, C., Seppanen, E. J., Orami, T., Granland, C. M., Francis, J., Yoannes, M., Corscadden, K. J., Ford, R., Jacoby, P., van den Biggelaar, A. H. J., Bakaletz, L. O., Cripps, A. W., Lehmann, D., Richmond, P. C., Pomat, W. S., Kirkham, L. A. S. & Thornton, R. B., 10 Aug 2021, In: Frontiers in Immunology. 12, 725244.Research output: Contribution to journal › Article › peer-review
Open Access -
Lack of effectiveness of 13-valent pneumococcal conjugate vaccination against pneumococcal carriage density in Papua New Guinean infants
Britton, K. J., Pickering, J. L., Pomat, W. S., de Gier, C., Nation, M. L., Pell, C. L., Granland, C. M., Solomon, V., Ford, R. L., Greenhill, A., Hinds, J., Moore, H. C., Richmond, P. C., Blyth, C. C., Lehmann, D., Satzke, C. & Kirkham, L. A. S., 7 Sep 2021, In: Vaccine. 39, 38, p. 5401-5409 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
PCV10 elicits Protein D IgG responses in Papua New Guinean children but has no impact on NTHi carriage in the first two years of life
Rahman, T., de Gier, C., Orami, T., Seppanen, E. J., Granland, C. M., Francis, J. P., Michael, A., Yoannes, M., Corscadden, K. J., Ford, R. L., Martinovich, K. M., Jacoby, P., van den Biggelaar, A. H. J., Lehmann, D., Richmond, P. C., Pomat, W. S., Thornton, R. B. & Kirkham, L. A. S., 11 Jun 2021, In: Vaccine. 39, 26, p. 3486-3492 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Targeting host-microbial interactions to develop otitis media therapies
Kirkham, L. A. S. & Thornton, R. B., Jun 2021, In: Microbiology Australia. 42, 2, p. 75-78 4 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Bacterial Reservoirs in the Middle Ear of Otitis-prone Children Are Associated with Repeat Ventilation Tube Insertion
Seppanen, E. J., Thornton, R. B., North, H. J. D., Corscadden, K. J., Wiertsema, S. P., Vijayasekaran, S., Coates, H. L., Jacoby, P., Richmond, P. C. & Kirkham, L. A. S., Feb 2020, (E-pub ahead of print) In: Pediatric Infectious Disease Journal. 39, 2, p. 91-96 6 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)
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Merck Investigator Studies Program - A cross-sectional observational study on the aetiology of recurrent acute otitis media in Western Australia in the PCV13-era: the WALACE study (Western Australian Aetiology of Acute and Chronic Ear Disease)
Kirkham, L., Richmond, P., Herbert, H., Vijayasekaran, S., Sim, G., Kuthubutheen, J., Swift, V. & Brennan-Jones, C.
Merck, Sharp & Dohme Australia
23/09/21 → 23/09/23
Project: Research
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Round 8 - A bacterial therapy to prevent otitis media – preparing for first-in-human studies
Kirkham, L., Richmond, P., Fulurija, A., Seppanen, E. & Strickland, D.
Government of Western Australia, Department of Health
1/07/20 → 28/02/23
Project: Research
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2018 - Cell Insight CX7 High Content System
Yeoh, G., Forrest, A., Ganss, R., Blancafort, P., Swaminatha Iyer, K., Pavlos, N., Xu, J., Kirkham, L., Dwivedi, G., Ingley, E., Davern, K., Kahler, C., Meehan, K., Lesterhuis, W., Hamzah, J., Prele, C. & Mutsaers, S.
National Health & Medical Research Council NHMRC
1/01/19 → 31/12/19
Project: Research
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MHRIF Round 22 - Lea-Ann Kirkham
Government of Western Australia, Department of Health
1/01/19 → 31/12/19
Project: Research