Research Output per year
Personal profile
Research
Dr Kirkham's research focus is on understanding the pathogenesis of bacterial respiratory infections and strategies to reduce the burden of disease, including development of improved vaccines. Current research areas include:
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract
Keywords
- Otitis media
- Pneumococcal disease
- Vaccine development
- Meningitis
- Bacterial infections
- Microbiology
Fingerprint Dive into the research topics where Lea-Ann Kirkham is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 17 Similar Profiles
Haemophilus influenzae
Medicine & Life Sciences
Otitis Media
Medicine & Life Sciences
Pneumococcal Vaccines
Medicine & Life Sciences
otitis media
Agriculture & Biology
Immunoglobulin G
Medicine & Life Sciences
Haemophilus
Medicine & Life Sciences
Conjugate Vaccines
Medicine & Life Sciences
Fucose
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2005 2019
Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children
Bhuiyan, M. U., Blyth, C. C., West, R., Lang, J., Rahman, T., Granland, C., de Gier, C., Borland, M. L., Thornton, R. B., Kirkham, L-A. S., Martin, A., Richmond, P. C., Smith, D. W., Jaffe, A. & Snelling, T. L., 2 Apr 2019, In : BMC Pulmonary Medicine. 19, 1, 9 p., 71.Research output: Contribution to journal › Article
Open Access
1
Citation
(Scopus)
Immunogenicity and immune memory after a pneumococcal polysaccharide vaccine booster in a high-risk population primed with 10-valent or 13-valent pneumococcal conjugate vaccine: A randomized controlled trial in Papua New Guinean children
van den Biggelaar, A. H. J., Pomat, W. S., Masiria, G., Wana, S., Nivio, B., Francis, J., Ford, R., Passey, M., Kirkham, L. A., Jacoby, P., Lehmann, D. & Richmond, P., 4 Feb 2019, In : Vaccines. 7, 1, 17.Research output: Contribution to journal › Article
Open Access
Conjugate Vaccines
Pneumococcal Vaccines
Randomized Controlled Trials
Population
Pneumococcal Infections
PCV7- and PCV10-Vaccinated Otitis-Prone Children in New Zealand Have Similar Pneumococcal and Haemophilus influenzae Densities in Their Nasopharynx and Middle Ear
de Gier, C., Granland, C. M., Pickering, J. L., Walls, T., Bhuiyan, M., Mills, N., Richmond, P. C., Best, E. J., Thornton, R. B. & Kirkham, L-A. S., 31 Jan 2019, In : Vaccines. 7, 1, 14 p., 14.Research output: Contribution to journal › Article
Open Access
Production of IgG2 antibodies to pneumococcal polysaccharides after vaccination of treated HIV patients may be augmented by IL-7Rα signaling in ICOS+ circulating T follicular-helper cells
Abudulai, L., Fernandez, S., Corscadden, K., Kirkham, L-A., Hunter, M., Post, J. J. & French, M., 24 Apr 2019, In : Frontiers in Immunology. 10, 9 p.Research output: Contribution to journal › Article
Open Access
Helper-Inducer T-Lymphocytes
Antibody Formation
Polysaccharides
Vaccination
Immunoglobulin G
2
Citations
(Scopus)
Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: A randomized controlled trial of 10-valent and 13-valent pneumococcal conjugate vaccine in Papua New Guinean infants
Pomat, W. S., Van Den Biggelaar, A. H. J., Wana, S., Francis, J. P., Solomon, V., Greenhill, A. R., Ford, R., Orami, T., Passey, M., Jacoby, P., Kirkham, L. A., Lehmann, D. & Richmond, P. C., 1 May 2019, In : Clinical Infectious Diseases. 68, 9, p. 1472-1481 10 p.Research output: Contribution to journal › Article
Open Access
Conjugate Vaccines
Pneumococcal Vaccines
Randomized Controlled Trials
Safety
Population
Projects 2008 2018
- 23 Finished
QIAcube HT workstation
Kirkham, L., Thornton, R., Richmond, P., Blyth, C., Bowen, A., Van Den Biggelaar, A., Prescott, S., Gamez Gamez, C., Strunk, T., Adams, L., Stick, S., Kicic, A., Le Souef, P., Laing, I., Hales, B., Baltic, S. & Pickering, J.
National Health & Medical Research Council NHMRC
1/01/17 → 31/12/17
Project: Research
Beyond qualitative pathogen detection: a pilot study to explore the next generation of diagnostic assays for childhood respiratory infection
Blyth, C., Kirkham, L., Thornton, R., Bhuiyan, M., Jacoby, P. & Smith, D.
1/01/16 → 31/12/17
Project: Research