• The University of Western Australia (M561), 35 Stirling Highway,

    6009 Perth


  • 700 Citations
  • 14 h-Index
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Personal profile


Dr Kirkham's research focus is on understanding the pathogenesis of bacterial respiratory infections and strategies to reduce the burden of disease, including development of improved vaccines. Current research areas include:
• Understanding the immunology and microbiology of respiratory infections in children
• Evaluation of pneumococcal conjugate vaccination schedules in at-risk populations
• Development of a bacterial therapy to prevent pathogens colonising the respiratory tract


  • Otitis media
  • Pneumococcal disease
  • Vaccine development
  • Meningitis
  • Bacterial infections
  • Microbiology

Fingerprint Dive into the research topics where Lea-Ann Kirkham is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
Haemophilus influenzae Medicine & Life Sciences
Otitis Media Medicine & Life Sciences
otitis media Agriculture & Biology
Pneumococcal Vaccines Medicine & Life Sciences
Immunoglobulin G Medicine & Life Sciences
Haemophilus Medicine & Life Sciences
Conjugate Vaccines Medicine & Life Sciences
Middle Ear Medicine & Life Sciences

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Research Output 2005 2019

  • 700 Citations
  • 14 h-Index
  • 42 Article
  • 2 Review article
  • 1 Abstract/Meeting Abstract
2 Citations (Scopus)

Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

Bhuiyan, M. U., Blyth, C. C., West, R., Lang, J., Rahman, T., Granland, C., de Gier, C., Borland, M. L., Thornton, R. B., Kirkham, L-A. S., Martin, A., Richmond, P. C., Smith, D. W., Jaffe, A. & Snelling, T. L., 2 Apr 2019, In : BMC Pulmonary Medicine. 19, 1, 9 p., 71.

Research output: Contribution to journalArticle

Open Access

High concentrations of middle ear antimicrobial peptides and proteins and proinflammatory cytokines are associated with detection of middle ear pathogens in children with recurrent acute otitis media

Seppanen, E. J., Thornton, R. B., Corscadden, K. J., Granland, C. M., Hibbert, J., Fuery, A., Wiertsema, S. P., Vijayasekaran, S., Coates, H. L., Jacoby, P., Currie, A., Richmond, P. C. & Kirkham, L. A. S., 26 Dec 2019, In : PLoS One. 14, 12, e0227080.

Research output: Contribution to journalArticle

Open Access
antimicrobial proteins
otitis media
Otitis Media with Effusion
antimicrobial peptides
Otitis Media
1 Citation (Scopus)

Immunogenicity and immune memory after a pneumococcal polysaccharide vaccine booster in a high-risk population primed with 10-valent or 13-valent pneumococcal conjugate vaccine: A randomized controlled trial in Papua New Guinean children

van den Biggelaar, A. H. J., Pomat, W. S., Masiria, G., Wana, S., Nivio, B., Francis, J., Ford, R., Passey, M., Kirkham, L. A., Jacoby, P., Lehmann, D. & Richmond, P., 4 Feb 2019, In : Vaccines. 7, 1, 17.

Research output: Contribution to journalArticle

Open Access
Conjugate Vaccines
Pneumococcal Vaccines
Randomized Controlled Trials
Pneumococcal Infections
2 Citations (Scopus)

PCV7- and PCV10-Vaccinated Otitis-Prone Children in New Zealand Have Similar Pneumococcal and Haemophilus influenzae Densities in Their Nasopharynx and Middle Ear

de Gier, C., Granland, C. M., Pickering, J. L., Walls, T., Bhuiyan, M., Mills, N., Richmond, P. C., Best, E. J., Thornton, R. B. & Kirkham, L-A. S., 31 Jan 2019, In : Vaccines. 7, 1, 14 p., 14.

Research output: Contribution to journalArticle

Open Access
Open Access
Helper-Inducer T-Lymphocytes
Antibody Formation
Immunoglobulin G

Projects 2008 2019