Lawrence Beilin

Emeritus Professor, MB BS MD Lond., MA Oxf., FRACP, FRCP, FCSANZ

  • The University of Western Australia (M570), 35 Stirling Highway,

    6009 Perth

    Australia

  • 27545 Citations
  • 81 h-Index
1987 …2022
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Research Output 1987 2019

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Article
2019

Added predictive value of high uric acid for cardiovascular events in the Ambulatory Blood Pressure International Study

Reboldi, G., Verdecchia, P., Saladini, F., Pane, M., Beilin, L. J., Eguchi, K., Imai, Y., Kario, K., Ohkubo, T., Pierdomenico, S. D., Schwartz, J. E., Wing, L. & Palatini, P., 1 Jul 2019, In : Journal of Clinical Hypertension. 21, 7, p. 966-974 9 p.

Research output: Contribution to journalArticle

Uric Acid
Blood Pressure
Proportional Hazards Models
Cohort Studies
Survival

Change in Blood Pressure Variability Among Treated Elderly Hypertensive Patients and Its Association With Mortality

Second Australian National Blood Pressure Study Group † & Second Australian National Blood Pressure Study Group <xref ref-type="author-note" rid="jah34572-note-1001"></xref>, 5 Nov 2019, In : Journal of the American Heart Association. 8, 21, p. e012630

Research output: Contribution to journalArticle

Blood Pressure
Mortality
Antihypertensive Agents
Hypertension
Hypotension

Cohort Profile: The ASPREE Longitudinal Study of Older Persons (ALSOP)

McNeil, J. J., Woods, R. L., Ward, S. A., Britt, C. J., Lockery, J. E., Beilin, L. J. & Owen, A. J., 1 Aug 2019, In : International Journal of Epidemiology. 48, 4, p. 1048-1049H 10 p., dyy279.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

EpiGen Consortium, May 2019, In : International Journal of Obesity. 43, 5, p. 974-988 15 p.

Research output: Contribution to journalArticle

Open Access
Adiposity
Epigenomics
Methylation
Parturition
Umbilical Cord

Effect of weight loss on neutrophil resolvins in the metabolic syndrome

Barden, A., Shinde, S., Tsai, I. J., Croft, K. D., Beilin, L. J., Puddey, I. B. & Mori, T. A., 1 Sep 2019, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 148, p. 25-29 5 p.

Research output: Contribution to journalArticle

Inflammation Mediators
Weight Loss
Neutrophils
Weights and Measures
Volunteers
2 Citations (Scopus)

Epigenetic age acceleration in adolescence associates with BMI, inflammation and risk score for middle age cardiovascular disease

Huang, R. C., Lillycrop, K. A., Beilin, L. J., Godfrey, K. M., Anderson, D., Mori, T. A., Rauschert, S., Craig, J. M., Oddy, W. H., Ayonrinde, O. T., Pennell, C. E., Holbrook, J. D. & Melton, P. E., Jul 2019, In : The Journal of clinical endocrinology and metabolism. 104, 7, p. 3012-3024 13 p.

Research output: Contribution to journalArticle

Epigenomics
Cardiovascular Diseases
Inflammation
Adiposity
DNA Methylation
Life Style
Diet
Pregnancy
Health
Weight Gain
2 Citations (Scopus)

Features of the metabolic syndrome in late adolescence are associated with impaired testicular function at 20 years of age

Hart, R. J., Doherty, D. A., Mori, T. A., Adams, L. A., Huang, R-C., Minaee, N., Handelsman, D. J., McLachlan, R., Norman, R. J., Dickinson, J. E., Olynyk, J. K. & Beilin, L. J., 1 Mar 2019, In : Human Reproduction. 34, 3, p. 389-402 14 p.

Research output: Contribution to journalArticle

Testosterone
Organized Financing
Serum
Insulin Resistance
Western Australia

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

Early Growth Genetics (EGG) Consortium & BIOS consortium, 4 Sep 2019, In : Science Advances. 5, 9, eaaw3095.

Research output: Contribution to journalArticle

Open Access
health
time measurement
obesity
genome
loci
16 Citations (Scopus)

Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American and Australian cohorts

Santos, S., Voerman, E., Amiano, P., Barros, H., Beilin, L. J., Bergstrom, A., Charles, M-A., Chatzi, L., Chevrier, C., Chrousos, G. P., Corpeleijn, E., Costa, O., Costet, N., Crozier, S., Devereux, G., Doyon, M., Eggesbo, M., Fantini, M. P., Farchi, S., Forastiere, F. & 67 othersGeorgiu, V., Godfrey, K. M., Gori, D., Grote, V., Hanke, W., Hertz-Picciotto, I., Heude, B., Hivert, M-F., Hryhorczuk, D., Huang, R-C., Inskip, H., Karvonen, A. M., Kenny, L. C., Koletzko, B., Kupers, L. K., Lagstrom, H., Lehmann, I., Magnus, P., Majewska, R., Makela, J., Manios, Y., McAuliffe, F. M., McDonald, S. W., Mehegan, J., Melen, E., Mommers, M., Morgen, C. S., Moschonis, G., Murray, D., Ni Chaoimh, C., Nohr, E. A., Andersen, A-M. N., Oken, E., Oostvogels, A. J. J. M., Pac, A., Papadopoulou, E., Pekkanen, J., Pizzi, C., Polanska, K., Porta, D., Richiardi, L., Rifas-Shiman, S. L., Roeleveld, N., Ronfani, L., Santos, A. C., Standl, M., Stigum, H., Stoltenberg, C., Thiering, E., Thijs, C., Torrent, M., Tough, S. C., Trnovec, T., Turner, S., van Gelder, M. M. H. J., van Rossem, L., von Berg, A., Vrijheid, M., Vrijkotte, T. G. M., West, J., Wijga, A. H., Wright, J., Zvinchuk, O., Sorensen, T. I. A., Lawlor, D. A., Gaillard, R. & Jaddoe, V. W. V., Jul 2019, In : Bjog-an International Journal of Obstetrics and Gynaecology. 126, 8, p. 984-995 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

EGG Consortium, May 2019, In : Nature Genetics. 51, 5, p. 804-814 17 p.

Research output: Contribution to journalArticle

Maternal Smoking During Pregnancy Induces Persistent Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk

Rauschert, S., Melton, P. E., Burdge, G., Craig, J. M., Godfrey, K. M., Holbrook, J. D., Lillycrop, K., Mori, T. A., Beilin, L. J., Oddy, W. H., Pennell, C. & Huang, R-C., 5 Sep 2019, In : Frontiers in Genetics. 10, 15 p., 770.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Küpers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W. & 107 othersEverson, T. M., Xu, C. J., Huang, R. C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M. R., Bergström, A., Örtqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Håberg, S. E., Sørensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melén, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M. F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Davey Smith, G., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 1 Dec 2019, In : Nature Communications. 10, 1, 1893.

Research output: Contribution to journalArticle

Open Access
methylation
DNA Methylation
Meta-Analysis
Methylation
deoxyribonucleic acid
1 Citation (Scopus)

The effects of omega-3 fatty acid supplementation upon interleukin-12 and interleukin-18 in chronic kidney disease patients

Yong, K., Mori, T., Chew, G., Beilin, L. J., Puddey, I., Watts, G. F., Irish, A., Dogra, G., Boudville, N. & Lim, W., Sep 2019, In : Journal of Renal Nutrition. 29, 5, p. 377-385 9 p.

Research output: Contribution to journalArticle

Interleukin-18
Omega-3 Fatty Acids
Interleukin-12
Chronic Renal Insufficiency
C-Reactive Protein

The relationship between pulse pressure and inflammation with left ventricular diastolic dysfunction in chronic kidney disease patients

Yong, K., Mori, T., Chew, G., Beilin, L. J., Puddey, I., Watts, G., Dogra, G., Boudville, N. & Lim, W., 12 Feb 2019, In : Internal Medicine Journal. 49, 2, p. 240-247

Research output: Contribution to journalArticle

Left Ventricular Dysfunction
Chronic Renal Insufficiency
Interleukin-18
Interleukin-12
Blood Pressure
2018
Open Access
menarche
Menarche
cohort studies
young adults
childhood
3 Citations (Scopus)

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

for the BIOS Consortium & for the GLOBAL Meth QTL Consortium, Dec 2018, In : EBioMedicine. 38, p. 206-216

Research output: Contribution to journalArticle

Open Access
DNA Methylation
Smoking
Mothers
Phenotype
Waist Circumference
4 Citations (Scopus)

Cardiometabolic Risk Factors at 5 Years After Omega-3 Fatty Acid Supplementation in Infancy

See, V. H. L., Mori, T. A., Prescott, S. L., Beilin, L. J., Burrows, S. & Huang, R-C., Jul 2018, In : Pediatrics. 142, 1, p. 1-11

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Confidence Intervals
Adipokines
Waist Circumference
Insulin Resistance
8 Citations (Scopus)
Open Access
Vegetables
Atherosclerosis
Common Carotid Artery
Carotid Intima-Media Thickness
Phytochemicals
14 Citations (Scopus)
124 Downloads (Pure)
Open Access
File
Mental Health
Body Mass Index
Adiposity
Depression
Inflammation
114 Citations (Scopus)

Effect of aspirin on all-cause mortality in the healthy elderly

McNeil, J. J., Nelson, M. R., Woods, R. L., Lockery, J. E., Wolfe, R., Reid, C. M., Kirpach, B., Shah, R. C., Ives, D. G., Storey, E., Ryan, J., Tonkin, A. M., Newman, A. B., Williamson, J. D., Margolis, K. L., Ernst, M. E., Abhayaratna, W. P., Stocks, N., Fitzgerald, S. M., Orchard, S. G. & 8 othersTrevaks, R. E., Beilin, L. J., Donnan, G. A., Gibbs, P., Johnston, C. I., Radziszewska, B., Grimm, R. & Murray, A. M., 18 Oct 2018, In : New England Journal of Medicine. 379, 16, p. 1519-1528 10 p.

Research output: Contribution to journalArticle

Aspirin
Mortality
Placebos
Cause of Death
Confidence Intervals
151 Citations (Scopus)

Effect of aspirin on cardiovascular events and bleeding in the healthy elderly

ASPREE Investigator Group, 18 Oct 2018, In : New England Journal of Medicine. 379, 16, p. 1509-1518 10 p.

Research output: Contribution to journalArticle

Aspirin
Hemorrhage
Cardiovascular Diseases
Placebos
Primary Prevention
78 Citations (Scopus)

Effect of aspirin on disability-free survival in the healthy elderly

McNeil, J. J., Woods, R. L., Nelson, M. R., Reid, C. M., Kirpach, B., Wolfe, R., Storey, E., Shah, R. C., Lockery, J. E., Tonkin, A. M., Newman, A. B., Williamson, J. D., Margolis, K. L., Ernst, M. E., Abhayaratna, W. P., Stocks, N., Fitzgerald, S. M., Orchard, S. G., Trevaks, R. E., Beilin, L. J. & 7 othersDonnan, G. A., Gibbs, P., Johnston, C. I., Ryan, J., Radziszewska, B., Grimm, R. & Murray, A. M., 18 Oct 2018, In : New England Journal of Medicine. 379, 16, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

Aspirin
Survival
Placebos
Dementia
Hemorrhage
10 Citations (Scopus)

Glomerular hyperfiltration is a predictor of adverse cardiovascular outcomes

Reboldi, G., Verdecchia, P., Fiorucci, G., Beilin, L. J., Eguchi, K., Imai, Y., Kario, K., Ohkubo, T., Pierdomenico, S. D., Schwartz, J. E., Wing, L., Saladini, F. & Palatini, P., 1 Jan 2018, In : Kidney International. 93, 1, p. 195-203 9 p.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Blood Pressure
Proportional Hazards Models
Body Mass Index
Smoking
Adiposity
Young Adult
Smoking
Mothers
Depression
2 Citations (Scopus)

Night-time ambulatory blood pressure is the best pretreatment blood pressure predictor of 11-year mortality in treated older hypertensives

ANBP2 Management Committee & Beilin, L. J., 1 Oct 2018, In : Blood Pressure Monitoring. 23, 5, p. 237-243 7 p.

Research output: Contribution to journalArticle

Blood Pressure
Mortality
Confidence Intervals
Nurses
Placebos
6 Citations (Scopus)
Vegetables
Nitrates
Cross-Over Studies
Randomized Controlled Trials
Blood Pressure
1 Citation (Scopus)

Relation of Alcohol Consumption to Risk of Heart Failure in Patients Aged 65 to 84 Years With Hypertension

Second Australian National Blood Pressure Study Management Committee, 15 Oct 2018, In : American Journal of Cardiology. 122, 8, p. 1352-1358 7 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Heart Failure
Hypertension
Cardiomyopathies
Drinking
6 Citations (Scopus)
187 Downloads (Pure)
Open Access
File
Sex Characteristics
Pregnancy
Mothers
Pediatric Obesity
Weight Gain
6 Citations (Scopus)
coenzyme Q10
Inflammation Mediators
Leukotrienes
Omega-3 Fatty Acids
Chronic Renal Insufficiency
6 Citations (Scopus)
38 Downloads (Pure)
Open Access
File
Inflammation Mediators
Medical problems
Type 2 Diabetes Mellitus
Wine
Alcohols
8 Citations (Scopus)

Visit-to-visit (long-term) and ambulatory (short-term) blood pressure variability to predict mortality in an elderly hypertensive population

Chowdhury, E. K., Wing, L. M. H., Jennings, G. L. R., Beilin, L. J. & Reid, C. M., 1 May 2018, In : Journal of Hypertension. 36, 5, p. 1059-1067 9 p.

Research output: Contribution to journalArticle

Blood Pressure
Mortality
Population
Ambulatory Care
Proportional Hazards Models
89 Downloads (Pure)
Open Access
File
Health
HDL Cholesterol
Sleep
Construction Industry
Glucose
2017
20 Citations (Scopus)

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

Lillycrop, K., Murray, R., Cheong, C., Teh, A. L., Clarke-Harris, R., Barton, S., Costello, P., Garratt, E., Cook, E., Titcombe, P., Shunmuganathan, B., Liew, S. J., Chua, Y-C., Lin, X., Wu, Y., Burdge, G. C., Cooper, C., Inskip, H. M., Karnani, N., Hopkins, J. C. & 14 othersChilds, C. E., Chavez, C. P., Calder, P. C., Yap, F., Lee, Y. S., Chong, Y. S., Melton, P., Beilin, L., Huang, R-C., Gluckman, P. D., Harvey, N., Hanson, M. A., Holbrook, J. D. & Godfrey, K. M., Mar 2017, In : EBioMedicine. 19, p. 60–72

Research output: Contribution to journalArticle

Open Access
Methylation
Adiposity
DNA Methylation
Genetic Epigenesis
Parturition
3 Citations (Scopus)
137 Downloads (Pure)
Open Access
File
Inflammation Mediators
Wine
Eicosanoids
Blood pressure
Cytochrome P-450 Enzyme System
23 Citations (Scopus)
Vascular Diseases
Nitrates
Cohort Studies
Vegetables
Prospective Studies
18 Citations (Scopus)

Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study

McNeil, J. J., Woods, R. L., Nelson, M. R., Murray, A. M., Reid, C. M., Kirpach, B., Storey, E., Shah, R. C., Wolfe, R. S., Tonkin, A. M., Newman, A. B., Williamson, J. D., Lockery, J. E., Margolis, K. L., Ernst, M. E., Abhayaratna, W. P., Stocks, N., Fitzgerald, S. M., Trevaks, R. E., Orchard, S. G. & 6 othersBeilin, L. J., Donnan, G. A., Gibbs, P., Johnston, C. I., Grimm, R. H. & ASPREE Investigator Group, 12 Oct 2017, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 72, 11, p. 1586-1593 8 p.

Research output: Contribution to journalArticle

Aspirin
Dementia
Creatinine
Medical History Taking
Placebos
12 Citations (Scopus)
214 Downloads (Pure)
Open Access
File
Allium
Vascular Diseases
Vegetables
Phytochemicals
Confidence Intervals
2 Citations (Scopus)

Early life factors, obesity r, and the metabolome of young adults

Rauschert, S., Mori, T. A., Beilin, L. J., Jacoby, P., Uhl, O., Koletzko, B., Oddy, W. H. & Hellmuth, C., 1 Sep 2017, In : Obesity. 25, 9, p. 1549-1555 7 p.

Research output: Contribution to journalArticle

Metabolome
Breast Feeding
Young Adult
Obesity
Waist Circumference
5 Citations (Scopus)
Inflammation Mediators
Omega-3 Fatty Acids
Randomized Controlled Trials
F2-Isoprostanes
Eicosapentaenoic Acid
2 Citations (Scopus)

Fatness and Fitness With Cardiometabolic Risk Factors in Adolescents

Demmer, D. L., Beilin, L. J., Hands, B., Burrows, S., Cox, K. L., Oddy, W. H. & Mori, T. A., 1 Dec 2017, In : The Journal of clinical endocrinology and metabolism. 102, 12, p. 4467-4476 10 p.

Research output: Contribution to journalArticle

Blood pressure
Blood Pressure
HDL Cholesterol
Linear Models
Biochemistry
23 Citations (Scopus)

Infant feeding and growth trajectory patterns in childhood and body composition in young adulthood

Rzehak, P., Oddy, W. H., Mearin, M. L., Grote, V., Mori, T. A., Szajewska, H., Shamir, R., Koletzko, S., Weber, M., Beilin, L. J., Huang, R. C. & Koletzko, B., 1 Aug 2017, In : American Journal of Clinical Nutrition. 106, 2, p. 568-580 13 p.

Research output: Contribution to journalArticle

Open Access
Body Composition
Growth
Breast Feeding
Infant Formula
Cohort Studies
23 Citations (Scopus)

Infant nutrition and maternal obesity influence the risk of non-alcoholic fatty liver disease in adolescents

Ayonrinde, O. T., Oddy, W. H., Adams, L. A., Mori, T. A., Beilin, L. J., de Klerk, N. & Olynyk, J. K., 1 Sep 2017, In : Journal of Hepatology. 67, 3, p. 568-576 9 p.

Research output: Contribution to journalArticle

Obesity
Mothers
Milk
Breast Feeding
Pregnancy
1 Citation (Scopus)

Long-term survival following the development of heart failure in an elderly hypertensive population

Sahle, B. W., Owen, A. J., Wing, L. M. H., Beilin, L. J., Krum, H., Reid, C. M. & The Second Australian National Blood Pressure Study Management Committee, 1 Dec 2017, In : Cardiovascular Therapeutics. 35, 6, e12303.

Research output: Contribution to journalArticle

Heart Failure
Survival
Population
Mortality
Thiazides
8 Citations (Scopus)

Masked tachycardia. A predictor of adverse outcome in hypertension

Palatini, P., Reboldi, G., Beilin, L. J., Casiglia, E., Eguchi, K., Imai, Y., Kario, K., Ohkubo, T., Pierdomenico, S. D., Schwartz, J. E., Wing, L. M. H. & Verdecchia, P., 2017, In : Journal of Hypertension. 35, 3, p. 487-492 6 p.

Research output: Contribution to journalArticle

Tachycardia
Hypertension
Heart Rate
Mortality
Confidence Intervals
8 Citations (Scopus)

Relationships between depression and anxiety symptoms scores and blood pressure in young adults

Bhat, S. K., Beilin, L. J., Robinson, M., Burrows, S. & Mori, T. A., Oct 2017, In : Journal of Hypertension. 35, 10, p. 1983-1991

Research output: Contribution to journalArticle

Young Adult
Anxiety
Depression
Blood Pressure
Life Style
4 Citations (Scopus)
117 Downloads (Pure)

Sex differences in the association of phospholipids with components of the metabolic syndrome in young adults

Rauschert, S., Uhl, O., Koletzko, B., Mori, T. A., Beilin, L. J., Oddy, W. H. & Hellmuth, C., 28 Mar 2017, In : Biology of Sex Differences. 8, 10.

Research output: Contribution to journalArticle

Open Access
File
Sex Characteristics
young adult
Young Adult
Phospholipids
contraceptive
2016
13 Citations (Scopus)
212 Downloads (Pure)
Open Access
File
Polycystic Ovary Syndrome
Phenotype
Adiposity
Gastroenterology
Insulin Resistance
34 Citations (Scopus)
213 Downloads (Pure)

A randomized controlled trial of the effects of n-3 fatty acids on resolvins in chronic kidney disease.

Mas, E., Barden, A., Burke, V., Beilin, L., Watts, G., Huang, R-C., Puddey, I., Irish, A. & Mori, T., 13 Apr 2016, In : Clinical Nutrition. 35, 2, p. 331-336 6 p.

Research output: Contribution to journalArticle

Open Access
File
Omega-3 Fatty Acids
Chronic Renal Insufficiency
Randomized Controlled Trials
coenzyme Q10
Lipids