• The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

  • 232 Citations
  • 9 h-Index
20092020
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Research Output 2009 2019

  • 232 Citations
  • 9 h-Index
  • 14 Article
  • 5 Review article
  • 1 Abstract/Meeting Abstract
2019

Mechanical abnormalities of the airway wall in adult mice after intrauterine growth restriction

Noble, P., Kowlessur, D., Larcombe, A., Donovan, G. M. & Wang, K., 23 Aug 2019, In : Frontiers in Physiology. 10, p. 1073

Research output: Contribution to journalArticle

Open Access
Growth
Mechanics
Smooth Muscle
Pressure
Control Groups
Open Access
Smooth Muscle
Parturition
Muscle Contraction
Sheep
Pregnancy
2018
6 Citations (Scopus)

Foetal growth restriction in mice modifies postnatal airway responsiveness in an age and sex-dependent manner

Wang, K. C., Larcombe, A. N., Berry, L. J., Morton, J. S., Davidge, S. T., James, A. L. & Noble, P. B., 25 Jan 2018, In : Clinical Science. 132, 2, p. 273-284

Research output: Contribution to journalArticle

Fetal Development
Growth
Asthma
Lung
Pregnancy
4 Citations (Scopus)

Independent and combined effects of airway remodelling and allergy on airway responsiveness

Wang, K. C., Le Cras, T. D., Larcombe, A. N., Zosky, G. R., Elliot, J. G., James, A. L. & Noble, P. B., 14 Feb 2018, In : Clinical Science. 132, 3, p. 327-338 CS20171386.

Research output: Contribution to journalArticle

Airway Remodeling
Hypersensitivity
Ovalbumin
Smooth Muscle
Doxycycline
7 Citations (Scopus)

The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults

Lock, M. C., Tellam, R. L., Botting, K. J., Wang, K. C. W., Selvanayagam, J. B., Brooks, D. A., Seed, M. & Morrison, J. L., 1 Dec 2018, In : Journal of Physiology. 596, 23, p. 5625-5640 16 p.

Research output: Contribution to journalArticle

MicroRNAs
Cardiac Myocytes
Heart Diseases
Parturition
Zebrafish
2017
5 Citations (Scopus)

Akt signaling as a mediator of cardiac adaptation to low birth weight

Wang, K., Botting, K. J., Zhang, S., McMillen, C., Brooks, D. & Morrison, J., 1 May 2017, In : The Journal of Endocrinology. 233, 2, p. R81–R94

Research output: Contribution to journalReview article

Low Birth Weight Infant
MicroRNAs
Cardiac Myocytes
Cardiovascular Diseases
Placental Insufficiency
7 Citations (Scopus)

Increased heterogeneity of airway calibre in adult rats after hypoxia-induced intrauterine growth restriction

Wang, K. C. W., Morton, J. S., Davidge, S. T., Larcombe, A. N., James, A. L., Donovan, G. M. & Noble, P. B., 17 May 2017, In : Respirology. 22, 7, p. 1-7 7 p.

Research output: Contribution to journalArticle

Growth
Lung
Bronchoconstriction
Bronchoalveolar Lavage Fluid
Macrophages
2 Citations (Scopus)
Open Access
Transforming Growth Factor alpha
Optical Coherence Tomography
Diaphragm
Mechanics
Lung Diseases

SEX DEPENDENT EFFECTS ON AIRWAY RESPONSIVENESS OF MATERNAL HYPOXIA-INDUCED INTRAUTERINE GROWTH RESTRICTED JUVENILE MICE

Wang, K. C., Larcombe, A. N., Morton, J. S., Davidge, S. T., James, A. L. & Noble, P. B., Mar 2017, In : Respirology. 22, p. 36-36 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2015
12 Citations (Scopus)

IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb

Wang, K., Tosh, D. N., Zhang, S., McMillen, I. C., Duffield, J. A., Brooks, D. A. & Morrison, J. L., 1 Apr 2015, In : American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 308, 7, p. R627-R635 9 p.

Research output: Contribution to journalArticle

Somatomedin Receptors
Cardiomegaly
Low Birth Weight Infant
Birth Weight
Acetylation
14 Citations (Scopus)

Low birth weight activates the renin-angiotensin system, but limits cardiac angiogenesis in early postnatal life

Wang, K. C. W., Brooks, D. A., Summers-Pearce, B., Bobrovskaya, L., Tosh, D. N., Duffield, J. A., Botting, K. J., Zhang, S., Caroline McMillen, I. & Morrison, J. L., 3 Feb 2015, In : Physiological Reports. 3, 2, 16 p., e12270.

Research output: Contribution to journalArticle

Open Access
Low Birth Weight Infant
Renin-Angiotensin System
Messenger RNA
Autophagy
DNA Methylation
15 Citations (Scopus)

The periconceptional environment and cardiovascular disease: Does in vitro embryo culture and transfer influence cardiovascular development and health?

Padhee, M., Zhang, S., Lie, S., Wang, K. C., Botting, K. J., Caroline McMillen, I., Maclaughlin, S. M. & Morrison, J. L., 18 Feb 2015, In : Nutrients. 7, 3, p. 1378-1425 48 p.

Research output: Contribution to journalReview article

Open Access
assisted reproductive technologies
Assisted Reproductive Techniques
embryo culture
Embryo Transfer
embryo transfer
2014
6 Citations (Scopus)

Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus

Lie, S., Hui, M., McMillen, I. C., Muhlhausler, B. S., Posterino, G. S., Dunn, S. L., Wang, K. C., Botting, K. J. & Morrison, J. L., 15 Mar 2014, In : American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 306, 6, p. R429-R437 9 p.

Research output: Contribution to journalArticle

rosiglitazone
Peroxisome Proliferator-Activated Receptors
Cardiac Myocytes
Sheep
Fetus
2013
19 Citations (Scopus)

Alteration of cardiac glucose metabolism in association to low birth weight: experimental evidence in lambs with left ventricular hypertrophy

Wang, K. C. W., Lim, C. H., McMillen, I. C., Duffield, J. A., Brooks, D. A. & Morrison, J. L., Nov 2013, In : Metabolism: clinical and experimental. 62, 11, p. 1662-1672 11 p.

Research output: Contribution to journalArticle

Low Birth Weight Infant
Left Ventricular Hypertrophy
Glucose
Facilitative Glucose Transport Proteins
Fatty Acids
2012
17 Citations (Scopus)

Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus

Wang, K. C. W., Brooks, D. A., Thornburg, K. L. & Morrison, J. L., Nov 2012, In : Journal of Physiology. 590, 21, p. 5425-5437 13 p.

Research output: Contribution to journalArticle

Somatomedin Receptors
Cardiac Myocytes
Hypertrophy
Sheep
Fetus
40 Citations (Scopus)

Early origins of heart disease: Low birth weight and determinants of cardiomyocyte endowment

Botting, K. J., Wang, K. C. W., Padhee, M., McMillen, I. C., Summers-Pearce, B., Rattanatray, L., Cutri, N., Posterino, G. S., Brooks, D. A. & Morrison, J. L., Sep 2012, In : Clinical and Experimental Pharmacology and Physiology. 39, 9, p. 814-823 10 p.

Research output: Contribution to journalReview article

Low Birth Weight Infant
Financial Management
Cardiac Myocytes
Heart Diseases
Apoptosis
11 Citations (Scopus)

Early origins of heart disease: Low birth weight and the role of the insulin-like growth factor system in cardiac hypertrophy

Wang, K. C., Botting, K. J., Padhee, M., Zhang, S., McMillen, I. C., Suter, C. M., Brooks, D. A. & Morrison, J. L., Nov 2012, In : Clinical and Experimental Pharmacology and Physiology. 39, 11, p. 958-964 7 p.

Research output: Contribution to journalReview article

Cardiomegaly
Low Birth Weight Infant
Somatomedins
Heart Diseases
Growth
18 Citations (Scopus)

IGF-2R-Mediated signaling results in hypertrophy of cultured cardiomyocytes from fetal sheep

Wang, K. C. W., Brooks, D. A., Botting, K. J. & Morrison, J. L., 1 Jun 2012, In : Biology of Reproduction. 86, 6, p. 1-8 8 p., 183.

Research output: Contribution to journalArticle

Cardiac Myocytes
Hypertrophy
Sheep
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Fetal Heart
2011
49 Citations (Scopus)

Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb

Wang, K. C. W., Zhang, L., McMillen, I. C., Botting, K. J., Duffield, J. A., Zhang, S., Suter, C. M., Brooks, D. A. & Morrison, J. L., 1 Oct 2011, In : The Journal of Physiology. 589, 19, p. 4709-4722 14 p.

Research output: Contribution to journalArticle

2009

Fetal heart growth: IGF-1 and sex

Morrison, J. L., Wang, K. C. W., Brooks, D. A. & Botting, K. J., May 2009, In : Expert Review of Obstetrics and Gynecology. 4, 3, p. 255-259 5 p.

Research output: Contribution to journalReview article

Fetal Heart
Fetal Development
Insulin-Like Growth Factor I
Cardiac Myocytes
Sheep