Research output per year
Research output per year
Personal profile
Biography
Professor Kevin Pfleger is Director, Biomedical and Health Innovation at The University of Western Australia (UWA) and the WA Life Sciences Innovation Hub, as well as Head of Molecular Endocrinology and Pharmacology at the Harry Perkins Institute of Medical Research (UWA Centre for Medical Research). He is also Chief Scientific Advisor to Dimerix Limited, an ASX-listed spin-out company from UWA, as well as Scientific Co-Founder of RAGE Biotech. Prof Pfleger was awarded his MA and PhD from Cambridge and Edinburgh Universities respectively, and relocated to Western Australia in October 2002. He was a National Health and Medical Research Council (NHMRC) Peter Doherty Research Fellow from 2005 to 2008, an Australian Research Council (ARC) Future Fellow from 2011 to 2014, and NHMRC RD Wright Fellow (Level 2) from 2015 to 2018. Prof Pfleger was elected as a Fellow of the British Pharmacological Society in 2021.
Roles and responsibilities
Director, Biomedical and Health Innovation
Head of Molecular Endocrinology and Pharmacology
Chair of Biodesign Australia and Perth Biodesign
Former President of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT)
Founding Co-Director of Australian Clinical Entepreneur Program
Education/Academic qualification
Natural Sciences - Pharmacology, MA, University of Cambridge
Molecular Endocrinology and Pharmacology, PhD, Strutural Determinants of GnRH Ligand-Receptor Interactions, University of Edinburgh
External positions
Chief Scientific Advisor, Dimerix Limited
Scientific Co-Founder, RAGE Biotech
Industry keywords
- Drug Discovery
- Medicine and Pharma
- Biotechnology
- Health
Research expertise keywords
- Assay technology
- Endocrinology—receptors
- Molecular pharmacology
- Protein interactions
- Bioluminescence resonance energy transfer (BRET)
- G protein-coupled receptors (GPCR)
- Dimerisation
- Heteromerisation
- Arrestin
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 8 Decent Work and Economic Growth -
SDG 9 Industry, Innovation, and Infrastructure
Fingerprint
Dive into the research topics where Kevin Pfleger is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 6 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Orexin receptor 2 (OX2R) exhibits ligand-dependent spatio-temporal pharmacology through Gαi:β-arrestin dynamics in response to Orexin-A and Orexin-B
Dale, N. C., Purbrick, H. G., Pfleger, K. D. & Johnstone, E. K., Jan 2026, In: Biochemical Pharmacology. 243, Part 2, 15 p., 117517.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Pancreatic Ductal Adenocarcinoma, β-blockers, and Antihistamines: A Clinical Trial Is Needed
Baker, J. G., Sloan, E. K., Pfleger, K. D. G., McCormick, P. J., Salmerón, C. & Insel, P. A., 2025, In: Function. 6, 1, 5 p., zqae050.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans
White, C. W., Platt, S., Kilpatrick, L. E., Dale, N., Abhayawardana, R. S., Dekkers, S., Kindon, N. D., Kellam, B., Stocks, M. J., Pfleger, K. D. G. & Hill, S. J., 19 Mar 2024, In: Science Signaling. 17, 828, eabl3758.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Link opens in a new tab Citations (Scopus)83 Downloads (Pure) -
Bioluminescence Resonance Energy Transfer ( BRET ) Technologies to Study GPCRs
Dale, N., White, C., Johnstone, L. & Pfleger, K., 2023, GPCRs as Therapeutic Targets. Gilchrist, A. (ed.). John Wiley & Sons, Vol. 1.Research output: Chapter in Book/Conference paper › Chapter › peer-review
-
GPCR heteromers: An overview of their classification, function and physiological relevance
Dale, N. C., Johnstone, E. K. M. & Pfleger, K. D. G., 30 Aug 2022, In: Frontiers in Endocrinology. 13, 13 p., 931573.Research output: Contribution to journal › Review article › peer-review
Open Access50 Link opens in a new tab Citations (Scopus)
Datasets
-
Data from: CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes
White, C. (Creator), Caspar, B. (Creator), Vanyai, H. (Creator), Pfleger, K. (Creator) & Hill, S. (Creator), Elsevier, 12 Feb 2020
DOI: 10.1016/j.chembiol.2020.01.010, https://ars.els-cdn.com/content/image/1-s2.0-S2451945620300350-mmc1.pdf
Dataset
-
IC250100027: ARC Training Centre for Microphysiological System Technology (MiPSET)
Pfleger, K. (Investigator 01) & Johnstone, L. (Investigator 02)
ARC Australian Research Council
1/01/26 → 31/12/30
Project: Research
-
Core Freeze Drying and Concentrating Platform to Support Biomedical Research
Flematti, G. (Chief Investigator), Chooi, H. (CoPI), Fox, A. (CoPI), Geddes, D. (CoPI), Kretzmann, J. (CoPI), Lister, R. (CoPI), Pfleger, K. (CoPI), Piggott, M. (CoPI), Smith, N. (CoPI) & Swaminatha Iyer, I. (CoPI)
1/01/26 → 31/12/26
Project: Research
-
Westside Collaboration Space
Pfleger, K. (Investigator 01)
Department of Health (Western Australia)
9/06/25 → 9/03/27
Project: Research
-
NHMRC Ideas Grant 2037777: Chemokines as novel nucleic acid sensors: a new function in innate immunity
White, C. (Investigator 01), Pfleger, K. (Investigator 02) & Stewart, A. (Investigator 03)
NHMRC National Health and Medical Research Council
1/01/25 → 31/12/27
Project: Research
-
WA Life Sciences Innovation Hub
Pfleger, K. (CoPI)
Department of Jobs Tourism Science and Innovation (Western Australia), 2022/GR000956
30/06/22 → 30/06/26
Project: Research