Personal profile
Biography
Dr Kevin Looi is a senior respiratory scientist whose research focuses on airway epithelial biology, chronic airway inflammation, and the development of translational therapeutic strategies for respiratory disease. His work aims to understand how environmental exposures and respiratory viruses affect airway epithelial barrier integrity, mucociliary function, and inflammatory responses, with the goal of identifying novel and accessible interventions to improve respiratory health outcomes, particularly for vulnerable populations.
Dr Looi has led and contributed to several competitively funded research programs examining viral respiratory infections, vaping-related airway injury, and innovative inhaled therapeutics, including the assessment of aerosolised bioactive compounds. His research integrates advanced experimental models, including well-differentiated primary airway epithelial cultures, alongside in vitro and in vivo systems and multi-omics approaches to bridge fundamental mechanistic insights with translational clinical relevance.
In addition to his laboratory research, Dr Looi actively collaborates with health advocacy organisations and policymakers to ensure that scientific findings inform public health initiatives and strategies aimed at preventing respiratory disease and improving community health outcomes.
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Collaborations and top research areas from the last five years
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A differentiated nasal epithelial cell model derived from children with acute wheeze and asthma
Watkinson, R. L., Montgomery, S. T., Berry, L., Gwatimba, A., Coleman, L. A., Khoo, S. K., Troy, N., Prastanti, F., Borland, M., Le Souef, P. N., Iosifidis, T., Looi, K., Laing, I. A. & Kicic, A., 2026, (Accepted/In press) In: Annals of Allergy, Asthma and Immunology. 136, 3, p. 272-281 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Analysis of Adherence Junctions in Rhinovirus-Infected Airway Epithelial Cells
Looi, K., Hirvonen, L. M. & Kicic, A., 27 Feb 2025, Rhinovirus: Methods and Protocols. Sajjan, U. (ed.). 1 ed. Humana Press Inc., Vol. 2903. p. 77-96 20 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Conference paper › Chapter › peer-review
1 Link opens in a new tab Citation (Scopus) -
Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium
Looi, K., Sutanto, E. N., Iosifidis, T., Berry, L. J., Kicic, A. & Stick, S. M., 2025, In: Frontiers in Cell and Developmental Biology. 13, 1532656.Research output: Contribution to journal › Article › peer-review
Open Access -
Innate epithelial and functional differences in airway epithelium of children with acute wheeze
Looi, K., Iosifidis, T., Harrison, S., Stick, S. M., LeSouef, P., Laing, I. A. & Kicic, A., 28 Jul 2025, In: Frontiers in Cell and Developmental Biology. 13, 13 p., 1606915.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Investigation of Differentiated Nasal Epithelial Responses to Infection with Clinical Isolates of Rhinovirus A and C
Watkinson, R. L., Bochkov, Y. A., Gern, J. E., Iosifidis, T., Looi, K., Laing, I. A. & Kicic, A., Feb 2025, Rhinovirus: Methods and Protocols. Sajjan, U. (ed.). 1 ed. Humana Press Inc., p. 113-139 27 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Conference paper › Chapter › peer-review
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Administering Diferuloylmethane-2 Via Aerosol Nebulization to Compromised Epithelium (ADVANCE)
Looi, K. (Investigator 01), Sutanto, E. (Investigator 02), Kicic, A. (Investigator 03), Stick, S. (Investigator 04), Ghildyal, R. (Investigator 05), Larcombe, A. (Investigator 06), Landwehr, K. (Investigator 07) & Hirvonen, L. (Investigator 08)
Department of Health (Western Australia)
8/01/24 → 7/01/27
Project: Research
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The airway epithelium in paediatric respiratory diseases
Sly, P. (Investigator 01), Fantino, E. (Investigator 02), Stick, S. (Investigator 03), Kicic, A. (Investigator 04), Sutanto, E. (Investigator 05), Looi, K. (Investigator 06), Garratt, L. (Investigator 07) & Ling, K.-M. (Investigator 08)
The University of Western Australia
1/01/12 → 31/12/12
Project: Research