• The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth

    Australia

  • 658 Citations
  • 13 h-Index
19962021
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Personal profile

Biography

Dr Kathy Fuller (Heel) earned her PhD from The University of Western Australia for research into the effects of post-surgical nutrition on gut immunity. She continued developing models of human disease as a postdoctoral researcher at Thrombogenix at Monash University designing and optimising in vivo models of thombogenesis, including real-time imaging of thrombus formation in rodent mesentery using fluorescence microscopy. Dr Fuller returned to UWA, becoming the lead academic of the Flow Cytometry and Cell Sorting facility where she gained extensive experience in flow cytometry including development and validation of the Sperm Chromatin Structure Assay (SCSA) for routine diagnostic use by Western Australian embryology clinics. In 2012 Dr Fuller joined Prof Wendy Erber in the Translational Cancer Pathology Laboratory as Senior Research Fellow where she is developing imaging cytometry protocols for the analysis of haematological malignancies and minimal residual disease. She lectures on standard flow and imaging flow cytometry techniques for research and diagnosis to third year biomedical science undergraduates and Masters postgraduate students. Dr Fuller has published in high impact journals such as Blood and Proceedings of the National Academy of Sciences.

Roles and responsibilities

Dr Fuller is the PathWest Scientist in Charge and UWA Adjunct Senior Research Fellow in the Translational Cancer Pathology Laboratory (TCPL). She has 20 years research and teaching experience using immunohistochemical and fluorescence microscopy for cell analysis including 12 years research and teaching experience with flow cytometry for phenotyping, viability and cellular activation assays. She has 15 years experience with laser microdissection for single/pure cell analysis including two years as the PALM Microlaser Technologies Australasian applications specialist. Dr Fuller leads the immunophenotyping analysis within the TCPL and is responsible for the optimisation of protocols, submission of grants and manuscripts, management of grant funding, and supervision of research staff and students.

Funding overview

Prof W Erber, Dr K Heel 2014, 'Myeloproliferative Neoplasms - Genomic Analysis of Megakaryocytes as a Strategy for Improving Therapy ', Perpetual Philanthropic Services
Prof S Collin, Dr K Shaw, Ass/Prof A Iwaniuk, Prof D Wylie, Dr K Heel 2014, 'Anatomical Proxies for Cognitive Abilities in Vertebrates', UWA Research Collaboration Awards.
Prof W Erber, Dr K Heel, Dr T Tabone 2013, 'Megakaryocyte pathology in Myeloproliferative Neoplasms', Cancer Council of Western Australia.
Prof S Collin, Prof C Duarte, Dr W Erskine, Prof B Marshall, Dr K Heel, Dr M Ziman, et al. 2012, 'Extending Capability in WA Flow Cytometry for Earth Oceans Environmental & Biomedical Science - State of the Art Four Laser & 12 Colour Analysis', ARC Linkage Infrastructure Equipment Facilities.
Prof W Erber, Prof J Reilly, Dr K Heel 2011, 'Megakaryocyte Biology in Myeloproliferative Neoplasms', UWA Research Collaboration Awards.
Prof S Collin, Prof R Northcutt, Dr K Shaw, Dr K Heel 2011, 'Developing Quantitative Measures of Brain Evolution in Early Vertebrates', UWA Research Collaboration Awards.
Prof D Sampson, Dr K Heel, et al 2010, 'NHMRC Equipment Grant: 405nm violet laser upgrade for the BD FACSCanto II', NHMRC Equipment Grants.
Prof D Sampson, Dr J Croser, Prof M Degli-Esposti, Prof S Dunlop, Prof D Hampson, Prof A Harvey, Dr K Heel, et al. 2008, 'A Core Western Australian Cell Sorting Facility - Ultra-Small Objects and Rare Cell Populations', ARC Linkage Infrastructure Equipment Facilities.
Ass/Prof P Rigby, Dr K Heel, Prof P Leedman, et al. 2007, 'NHMRC Equipment Grants - Becton Dickinson FACS Canto II Flow Cytometer with High Throughput Sampler', NHMRC Equipment Grants.
Ass/Prof P Rigby, Dr K Heel, Prof P Leedman, et al. 2007, 'Becton Dickinson FACS Canto II Flow Cytometer with High Throughput Sampler', UWA Faculty of Medicine, Dentistry and Health Sciences Infrastructure Grant.
Prof A Harvey, Em/Prof D Robertson, Dr K Heel 2006-2008, 'Gene Therapy and the Treatment of CNS Injury', Neurotrauma Research Program (NRP).
Prof A Harvey, Dr K Heel, Prof M Zheng, et al. 2005, 'NHMRC Equipment Grant: Fluorescent Attachment for the PALM Laser Microdissector', NHMRC Equipment Grants.
Dr H Dawkins, Prof J Harvey, Dr K Heel 2000, 'Optical Tweezer Unit for the Lotteries Laser Microdissection Facility', Lotteries Commission Medical Research Program.
K Heel, Prof J Hall 1997, 'Nutritional Enhancement of the Gut Immune System', Royal Perth Hospital Medical Research Foundation.
K Heel, Prof J Hall 1996-1997, 'Nutritional Enhancement of the Gut Immune System', The Arnold Yeldham and Mary Raine Foundation.
K Heel, Prof J Hall 1996, 'Immunopathology of the Rat Gut', Clive and Vera Ramaciotti Foundations: Equipment Grant-in-Aid.

Previous positions

Pathwest Scientist in Charge and UWA Adjunct Senior Research Fellow, Pathwest/UWA Translational Cancer Pathology Laboratory, The University of Western Australia (2016-present)
Senior Research Fellow, Pathwest/UWA Translational Cancer Pathology Laboratory, The University of Western Australia (2012-2016)
Academic in Charge of Flow Cytometry and Lecturer, Centre for Microscopy, Characterisation and Analysis (CMCA) (2006-2012)
Deputy Director and Associate Lecturer, Biomedical Imaging and Analysis Facility (BIAF), The University of Western Australia (2004-2006)
Manager/Operator, Lotteries Flow Cytometry Unit (LFCU), The University of Western Australia (2002-2003 0.7FTE)
Senior Research Officer, Lotteries Laser Microdissection Facility (LLMF), The University of Western Australia (2000-2002 1FTE, 2002 – 2003 0.3FTE)
Senior Research Scientist, Thrombogenix Pty. Ltd., Department of Medicine, Monash University (1998-2000)
Principal Scientific Investigator, Department of Surgery (Royal Perth Hospital), The University of Western Australia (1996-1998)

Teaching overview

Dr Fuller currently lectures on flow cytometry techniques for research and diagnosis of haematological malignancies to UWA students in Molecular Medicine (PATH2211), Pathology and Laboratory Medicine I (PATH3307), Infection and Immunity (MICR3340/5842), Haematology (PATH5161), and Molecular and Cellular Microbiology (MICR5831/MICR5846). She has also developed a module on imaging flow cytometry for the Diagnostics Methods I – Cellular Analysis (PATH5561) course.

Research

Development of imaging cytometry protocols for diagnosis and prognosis in haematological malignancies.
Investigating megakaryocyte dysregulation and myelofibrotic progression in Myeloproliferative Neoplasms (MPN)

Keywords

  • Flow cytometry (FACS—fluorescence activated cell sorting)
  • Imaging cytometry
  • Cellular manipulation with optical/laser tweezers
  • Single cell collection by laser microdissection for generic analysis

Fingerprint Dive into the research topics where Kathy Fuller is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
Flow Cytometry Medicine & Life Sciences
Megakaryocytes Medicine & Life Sciences
Fluorescence In Situ Hybridization Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Glutaminase Medicine & Life Sciences
Bone Marrow Medicine & Life Sciences
Branched Chain Amino Acids Medicine & Life Sciences
Chromosome Aberrations Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1996 2019

A standardised protocol for the evaluation of small extracellular vesicles in plasma by imaging flow cytometry

Armitage, J. D., Tan, D. B. A., Cha, L., Clark, M., Gray, E. S., Fuller, K. A. & Moodley, Y. P., 1 May 2019, In : Journal of Immunological Methods. 468, p. 61-66 6 p.

Research output: Contribution to journalArticle

Flow Cytometry
Lighting
Extracellular Vesicles
Fibrosis
Blood Platelets
Bone Marrow
Neoplasms
Megakaryocytes
1 Citation (Scopus)

“Immuno-flowFISH” for the Assessment of Cytogenetic Abnormalities in Chronic Lymphocytic Leukemia

Hui, H. Y. L., Clarke, K. M., Fuller, K. A., Stanley, J., Chuah, H. H., Ng, T. F., Cheah, C., McQuillan, A. & Erber, W. N., 1 May 2019, In : Cytometry Part A. 95, 5, p. 521-533 13 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Chromosome Aberrations
Fluorescence In Situ Hybridization
Flow Cytometry
Phenotype
1 Citation (Scopus)
Plasma Cells
Reference Values
Bone Marrow
Lymphocytes
Biopsy
5 Citations (Scopus)

Imaging flow cytometry to assess chromosomal abnormalities in chronic lymphocytic leukaemia

Hui, H., Fuller, K. A., Chuah, H., Liang, J., Sidiqi, H., Radeski, D. & Erber, W. N., 1 Feb 2018, In : Methods. 134-135, p. 32-40 9 p.

Research output: Contribution to journalArticle

Flow cytometry
B-Cell Chronic Lymphocytic Leukemia
Chromosome Aberrations
Flow Cytometry
Fluorescence In Situ Hybridization

Projects 2000 2021