• The University of Western Australia (M503), 35 Stirling Highway,

    6009 Perth

    Australia

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Personal profile

Biography

I graduated with a BSc (Hons) from the University of Melbourne. I undertook my PhD at the St Vincent’s Institute (Melbourne), where I studied the development and function of islet-specific T cells in autoimmune diabetes. I was also part of the Tom Mandel Islet Transplantation Programme, which offered access to islet transplantation for people with type 1 diabetes. After successfully completing my PhD, I joined the National Centre of Asbestos Related Disease (NCARD) in November 2014, and am currently a Cancer Council Western Australia Postdoctoral Fellow. 

Research interests

My research interests are in understanding the immunology mechanisms that underlie why some mesothelioma patients respond better to immunotherapy/chemotherapy but not others. The end goal is to utilise this knowledge to develop novel therapies and accurate predictors of treatment outcomes. I am particularly interested in understanding how the T cell repertoire influences treatment outcomes in cancer patients. 

Current projects

  1. The integration of mathematics and TCR sequencing to understand how an individual’s immune system contributes to therapy success
  2. The development of preclinical models to study why some patients develop severe autoimmunity after cancer immunotherapy
  3. The development of novel epigenetic targeting tools to improve mesothelioma therapy outcomes

 

Roles and responsibilities

  • Lead the murine TCR, mesothelioma-epiCRISPR and irae projects at NCARD
  • Manage and maintain preclinical models at NCARD 
  • Supervision of PhD and Honours students

Teaching overview

 Tumour Immunology Lecture

"Vaccines to immune checkpoint blockade" PATH3309 

Languages

English, Mandarin

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Autoimmune Diabetes, Immunology, PhD, University of Melbourne

Award Date: 13 Mar 2015

Science, BSc (Hons), University of Melbourne

Award Date: 15 Dec 2008

Biomedical Science, BBiomedSc, University of Melbourne

Award Date: 15 Dec 2007

Research expertise keywords

  • Immunology—T cell
  • T cell receptor
  • Tumour Immunology
  • Mouse models for disease
  • Mesothelioma
  • TCR sequencing
  • Type 1 Diabetes

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