John Papadimitriou

Emeritus Professor, BA MD PhD W.Aust., FRCPath, FRCPA, FIBiol

  • The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth

    Australia

  • 3353 Citations
  • 31 h-Index
1986 …2019
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Research Output 1986 2019

2019

Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network

Gao, J., Qin, A., Liu, D., Ruan, R., Wang, Q., Yuan, J., Cheng, T. S., Filipovska, A., Papadimitriou, J. M., Dai, K., Jiang, Q., Gao, X., Feng, J. Q., Takayanagi, H., Zhang, C. & Zheng, M. H., 20 Nov 2019, In : Science Advances. 5, 11, eaaw7215.

Research output: Contribution to journalArticle

Open Access
endoplasmic reticulum
mitochondria
homeostasis
chemotherapy
cancer

Exosomes-the enigmatic regulators of bone homeostasis (vol 6, 36, 2018)

Gao, M., Gao, W., Papadimitriou, J. M., Zhang, C., Gao, J. & Zheng, M., 25 Jan 2019, In : Bone Research. 7, 2 p., 3.

Research output: Contribution to journalArticle

Open Access

The potential influence of bone-derived modulators on the progression of Alzheimer's disease

Yuan, J., Meloni, B. P., Shi, T., Bonser, A., Papadimitriou, J. M., Mastaglia, F. L., Zhang, C., Zheng, M. & Gao, J., 7 May 2019, In : Journal of Alzheimer's Disease. 69, 1, p. 59-70 12 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Bone and Bones
Human Body
Neurodegenerative Diseases
Osteoporosis
2018
5 Citations (Scopus)

Exosomes—the enigmatic regulators of bone homeostasis

Gao, M., Gao, W., Papadimitriou, J. M., Zhang, C., Gao, J. & Zheng, M., 1 Dec 2018, In : Bone Research. 6, 1, 36.

Research output: Contribution to journalReview article

Open Access
Exosomes
Homeostasis
Bone and Bones
Osteogenesis
Wounds and Injuries
2017
1 Citation (Scopus)
Endometrioid Carcinoma
Cervix Uteri
Menorrhagia
Neoplasms
Cilia
2016
26 Citations (Scopus)

Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice

Richman, T., Spahr, H., Ermer, J., Davies, S., Viola, H., Bates, K., Papadimitriou, J., Hool, L., Rodger, J., Larsson, N. G., Rackham, O. & Filipovska, A., 20 Jun 2016, In : Nature Communications. 7, p. 1-14

Research output: Contribution to journalArticle

Open Access
RNA-Binding Proteins
Hooks
Electron Transport Complex IV
mice
Tunnels
2014
26 Citations (Scopus)

Lipid accumulation in dysferlin-deficient muscles

Grounds, M., Terrill, J., Radley-Crabb, H., Robertson, T., Papadimitriou, J., Spuler, S. & Shavlakadze, T., 2014, In : American Journal of Pathology. 184, 6, p. 1668-1676

Research output: Contribution to journalArticle

Muscular Diseases
Adipocytes
Psoas Muscles
Lipogenesis
Lipids
22 Citations (Scopus)

The biocompatibility of silk fibroin and acellular collagen scaffolds for tissue engineering in the ear

Shen, Y., Redmond, S., Papadimitriou, J., Teh, B., Yan, S., Wang, Y., Atlas, M., Marano, R., Zheng, M. & Dilley, R., 2014, In : Biomedical Materials. 9, p. 12pp

Research output: Contribution to journalArticle

2013
12 Citations (Scopus)

Cardiac α-actin over-expression therapy in dominant ACTA1 disease

Ravenscroft, G., Mcnamara, E., Griffiths, L. M., Papadimitriou, J., Hardeman, E. C., Bakker, T., Davies, K. E., Laing, N. & Nowak, K., 2013, In : Human Molecular Genetics. 22, 19, p. 3987-3997

Research output: Contribution to journalArticle

12 Citations (Scopus)

Evolution of Midurethral and Other Mesh Slings – A Critical Analysis

Petros, P. & Papadimitriou, J., 2013, In : Neurourology and Urodynamics. 32, 4, p. 399-406

Research output: Contribution to journalArticle

2011
20 Citations (Scopus)

Actin nemaline myopathy mouse reproduces disease, suggests other Actin Disease phenotypes and provides cautionary note on muscle transgene expression

Ravenscroft, G., Jackaman, C., Sewry, CA., Mcnamara, E., Squire, SE., Potter, AC., Papadimitriou, J., Griffiths, LM., Bakker, T., Davies, K., Laing, N. & Nowak, K., 2011, In : PLoS One. 6, 12, p. 1-13

Research output: Contribution to journalArticle

Open Access
43 Citations (Scopus)

Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies

Ravenscroft, G., Jackaman, C., Bringans, S., Papadimitriou, J., Griffiths, L. M., Mcnamara, E., Bakker, T., Davies, K. E., Laing, N. & Nowak, K., 2011, In : Brain. 134, p. 1101-1115

Research output: Contribution to journalArticle

2010
18 Citations (Scopus)

Immunoglobulin to zona pellucida 3 mediates ovarian damage and infertility after contraceptive vaccination in mice

Lloyd, M. L., Papadimitriou, J., O'Leary, S., Robertson, S. A. & Shellam, G., 2010, In : Journal of Autoimmunity. 35, p. 77-85

Research output: Contribution to journalArticle

2008

A mutant skeletal muscle alpha-actin gene, fused to enhanced green fluorescent protein (EGFP) produces a unique myopathic mouse model

Nowak, K. J., Ravenscroft, G., Jackaman, C., Lim, E. M., Sewry, C. A., Potter, A., Squire, S., Fisher, R., Baker, E., Feng, J. J., Marston, S., Fabian, V., Morling, P. J., Bakker, A. J., Griffiths, L. M., Papadimitriou, J., Davies, K. E. & Laing, N. G., 2008, 13th International Congress of the World Muscle Society. Newcastle, NSW ed. United Kingdom: Elsevier, Vol. 18. p. 785-786

Research output: Chapter in Book/Conference paperConference paper

2007

Cancer and Epigenetic Reversion - The Fundamental Role of Redox

Papadopulos-Eleopulos, E., Page, B. A. P., Causer, D., Turner, V. F. & Papadimitriou, J., 2007, In : The American Journal of Pathology. 171, 5, p. 1726-1727

Research output: Contribution to journalLetter

8 Citations (Scopus)

Cytomegalovirus Primary Envelopment at Large Nuclear Membrane Infoldings: What's New?

Pignatelli, S., Dal Monte, P., Landini, M. P., Severi, B., Nassiri, R., Gilloteaux, J., Papadimitriou, J. & Shellam, G., 2007, In : Journal of Virology. 81, 13, p. 7320-7321

Research output: Contribution to journalLetter

2006
1 Citation (Scopus)
6 Citations (Scopus)
Bone Resorption
Allografts
Sheep
Bone and Bones
Receptor Activator of Nuclear Factor-kappa B

No proof HIV antibodies are caused by a retroviral infection

Papadopulos-Eleopulos, E., Turner, V. F., Page, B. A. P., Papadimitriou, J. & Causer, D., 2006, In : Emergency Medicine Australasia. 18, p. 308-309

Research output: Contribution to journalLetter

2 Citations (Scopus)

Would Montagnier please clarify whether HIV or oxidation by the risk factors is the primary cause of AIDS

Papadopulos-Eleopulos, E., Page, B. A. P., Causer, D., Turner, V. F., Papadimitriou, J. & Alfonso, H. S., 2006, In : Medical Hypotheses. 67, p. 666-668

Research output: Contribution to journalLetter

2005
19 Citations (Scopus)

Correlation between Inactive Cathepsin D Expression and Retinal Changes in mcd2/mcd2 Transgenic Mice

Zhang, D., Brankov, M., Makhija, M. T., Robertson, T., Helmerhorst, E., Papadimitriou, J. & Rakoczy, E., 2005, In : Investigative Ophthalmology and Visual Science. 46, 9, p. 3031-3038

Research output: Contribution to journalArticle

Cathepsin D
Transgenic Mice
Retinal Pigments
Peptide Hydrolases
Epithelial Cells
19 Citations (Scopus)

Early diagnosis of breast cancer by hair diffraction

James, V., Corino, G., Robertson, T., Dutton, N., Halas, D., Boyd, A., Bentel, J. & Papadimitriou, J., 2005, In : International Journal of Cancer. 114, 6, p. 969-972

Research output: Contribution to journalArticle

Early Detection of Cancer
Breast Neoplasms
Vibrissae
Nude Mice
X-Ray Diffraction
11 Citations (Scopus)

Fibre diffraction of hair can provide a screening test for Alzheimer's Disease : a human and animal model study

James, V. J., Richardson, J. C., Robertson, T. A., Papadimitriou, J., Dutton, N., Maley, M., Berstein, L. M., Lantseva, O. E. & Martins, R., 2005, In : Medical Science Monitor. 11, 2, p. CR53-CR57

Research output: Contribution to journalArticle

Hair
Alzheimer Disease
Animal Models
Transgenic Mice
Genes
56 Citations (Scopus)

Functional Analysis of Granzyme M and Its Role in Immunity to Infection

Pao, L. I., Sumaria, N., Kelly, J. M., Van Dommelen, S., Cretney, E., Wallace, M. E., Anthony, D. A., Uldrich, A. P., Godfrey, D. I., Papadimitriou, J., Mullbacher, A., Degli-Esposti, M. A. & Smyth, M., 2005, In : Journal of Immunology. 175, 5, p. 3235-3243

Research output: Contribution to journalArticle

Granzymes
Immunity
Infection
Natural Killer Cells
Ectromelia
30 Citations (Scopus)
63 Citations (Scopus)

Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption

Pavlos, N., Xu, J., Riedel, D., Yeoh, J. S. G., Teitelbaum, S. L., Papadimitriou, J., Jahn, R., Ross, F. P. & Zheng, M., 2005, In : Molecular and Cellular Biology. 25, 12, p. 5253-5269

Research output: Contribution to journalArticle

Osteoclasts
Bone Resorption
trans-Golgi Network
rab3 GTP-Binding Proteins
Prenylation
2004
4 Citations (Scopus)

A critique of the Montagnier evidence for the HIV/AIDS hypothesis

Papadopulos-Eleopulos, E., Turner, V. F., Papadimitriou, J., Page, B., Causer, D., Alfonso, H., Mhlongo, S., Miller, T., Maniotis, A. & Fiala, C., 2004, In : Medical Hypotheses. 63, NA, p. 597-601

Research output: Contribution to journalReview article

Acquired Immunodeficiency Syndrome
Retroviridae
HIV
Antibodies
CD4-Positive T-Lymphocytes
74 Citations (Scopus)

Comparison of the morphological and biochemical changes in normal human lung fibroblasts and fibroblasts derived from lungs of patients with idiopathic pulmonary fibrosis during FasL-induced apoptosis

Moodley, Y. P., Caterina, P., Scaffidi, A. K., Misso, N., Papadimitriou, J., Mcanulty, R. J., Laurent, G. J., Thompson, P. & Knight, D. A., 2004, In : Journal of Pathology. 202, 4, p. 486-495

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Fibroblasts
Apoptosis
Lung
Caspase 3
20 Citations (Scopus)

Molecular characterisation of chondrocytes in autologous chondrocyte implantation

Zheng, M., King, E., Kirilak, L., Huang, L., Papadimitriou, J., Wood, D. & Xu, J., 2004, In : International Journal of Molecular Medicine. 13, 5, p. 623-628

Research output: Contribution to journalArticle

Chondrocytes
Cultured Cells
Aggrecans
Transforming Growth Factor beta Receptors
Calcitriol Receptors
14 Citations (Scopus)

Neonatal congenital microvillus atrophy

Pecache, N., Patole, S., Hagan, R., Hill, D., Charles, A. & Papadimitriou, J., 2004, In : Postgraduate Medical Journal. 80, 940, p. 80-83

Research output: Contribution to journalReview article

Atrophy
Somatostatin
Epidermal Growth Factor
Counseling
Early Diagnosis
15 Citations (Scopus)

Virus spread, tissue inflammation and antiviral response in brains of flavivirus susceptible and resistant mice acutely infected with Murray Valley encephalitis virus

Silvia, O. J., Pantelic, L., Mackenzie, J. S., Shellam, G., Papadimitriou, J. & Urosevic, N., 2004, In : Archives of Virology. 149, 3, p. 447-464

Research output: Contribution to journalArticle

Murray Valley encephalitis virus
Flavivirus
Antiviral Agents
Viruses
Inflammation
2003
42 Citations (Scopus)
ZAP-70 Protein-Tyrosine Kinase
Thymocytes
Protein-Tyrosine Kinases
Mutation
Knockout Mice
71 Citations (Scopus)
Vacuolar Proton-Translocating ATPases
Osteoclasts
Endocytosis
Apoptosis
Transferrin
21 Citations (Scopus)

Gangliocytic Paraganglioma of the Bronchus. A Case Report With Follow-up and Ultrastructural Assessment

Kee, A. R., Forrest, C. H., Brennan, B. A., Papadimitriou, J. & Glancy, R. J., 2003, In : American Journal of Surgical Pathology. 27, 10, p. 1380-1385

Research output: Contribution to journalReview article

Paraganglioma
Bronchi
Bronchoscopy
Pluripotent Stem Cells
Residual Neoplasm
2 Citations (Scopus)

High rates of HIV seropositivity in Africa - alternative explanation

Papadopulos-Eleopulos, E., Turner, V. F., Papadimitriou, J., Alfonso, H., Page, B. A. P., Causer, D., Mhlongo, S., Fiala, C. & Brink, A., 2003, In : International Journal of STD & AIDS. 14, 6, p. 426-427

Research output: Contribution to journalLetter

64 Citations (Scopus)
Immunologic Contraception
Muromegalovirus
Zona Pellucida
Health Services Needs and Demand
Virus Replication
37 Citations (Scopus)

Role of complement C5 and T lymphocytes in pathogenesis of disseminated and mucosal candidiasis in susceptible DBA/2 mice

Ashman, R. B., Papadimitriou, J., Fulurija, A., Drysdale, K. E., Farah, C. S., Naidoo, O. & Gotjamanos, T., 2003, In : Microbial Pathogenesis. 34, 2, p. 103-113

Research output: Contribution to journalArticle

Complement C5
Inbred DBA Mouse
Candidiasis
T-Lymphocytes
Kidney
2002
3 Citations (Scopus)

Heterosexual transmission of HIV in Africa is no higher than anywhere else

Papadopulos-Eleopulos, E., Turner, V. F., Papadimitriou, J., Alfonso, H., Page, B. A. P., Causer, D., Mhlongo, S., Miller, T. & Fiala, C., 2002, In : British Medical Journal. 324, 27 April, p. 1035

Research output: Contribution to journalLetter

125 Citations (Scopus)

Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model

Rakoczy, E., Zhang, D., Robertson, T., Barnett, N. L., Papadimitriou, J., Constable, I., Lai, C-M., Keri, G. (ed.) & Toth, I. (ed.), 2002, In : American Journal of Pathology. 161, 4, p. 1515-1524

Research output: Contribution to journalArticle

Macular Degeneration
Transgenic Mice
Retinal Pigments
Epithelial Cells
Geographic Atrophy
52 Citations (Scopus)

Stimulation of Mesothelial Cell Proliferation by Exudate Macrophages Enhances Serosal Wound Healing in a Murine Model

Mutsaers, S. E., Whitaker, D. & Papadimitriou, J., 2002, In : American Journal of Pathology. 160, 2, February, p. 681-692

Research output: Contribution to journalArticle

Exudates and Transudates
Wound Healing
Macrophages
Cell Proliferation
Wounds and Injuries
2001
16 Citations (Scopus)

Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas

Ward, B. K., Kumar, P., Turbett, G. R., Edmondston, J. E., Papadimitriou, J., Laing, N., Ingram, D. M., Minchin, R. F. & Ratajczak, T., 2001, In : Journal of Cancer Research and Clinical Oncology. 127, p. 109-115

Research output: Contribution to journalArticle

Immunophilins
Loss of Heterozygosity
Estrogen Receptors
Breast Neoplasms
Neoplasm Genes
2 Citations (Scopus)

Molecular cloning of the mouse homologue of Rab3c

Pavlos, N. J., Pavlos, N., Xu, J., Xu, J., Papadimitriou, J., Zheng, M. & Zheng, M. H., 2001, In : Journal of Molecular Endocrinology. 27, N/A, p. 117-122

Research output: Contribution to journalArticle

Molecular Cloning
Protein Isoforms
Brain
rab GTP-Binding Proteins
Transport Vesicles

Pax6 expression during optic nerve regeneration in the lizard

Ziman, M. R., Errington, S., Bartlett, C., Chen, P., Papadimitriou, J., Rodger, J., Dunlop, S. A. & Beazley, L. D., 2001, Proceedings of the Australian Neuroscience Society Twentyfirst Annual Meeting, Brisbane, January 28-31, 2001. Bartlett, P. (ed.). Brisbane, Australia

Research output: Chapter in Book/Conference paperOther chapter contribution

28 Citations (Scopus)
92 Citations (Scopus)

The histogenesis of giant cell tumour of bone: a model of interaction between neoplastic cells and osteoclasts

Zheng, M., Robbins, P., Xu, J., Huang, L., Wood, D. & Papadimitriou, J., 2001, In : Histology and Histopathology. 16, N/A, p. 297-307

Research output: Contribution to journalLiterature review

2000
11 Citations (Scopus)

Comparison of astrocytic and myocytic metabolic dysregulation in apolipoprotein E deficient and human apolipoprotein E transgenic mice

Robertson, T. A., Dutton, N., Martins, R., Taddei, K. & Papadimitriou, J., 2000, In : Neuroscience. 98, 2, p. 353-359

Research output: Contribution to journalArticle

Apolipoproteins E
Transgenic Mice
Bone Marrow
Hippocampus
Alleles
3 Citations (Scopus)

Controlled Production of Active Cathepsin D in Retinal Pigment Epithelial Cells Following Adenovirus-Mediated Gene Delivery

Lai, C-M., Robertson, T., Papadimitriou, J., Shen, W-Y., Daw, N., Constable, I. & Rakoczy, E., 2000, In : Molecular Therapy. 2, 5, p. 476-484

Research output: Contribution to journalArticle

Open Access
Cathepsin D
Retinal Pigments
Adenoviridae
Epithelial Cells
Genes
41 Citations (Scopus)

Gene expression of vascular endothelial growth factor in giant cell tumors of bone

Zheng, M., Xu, J., Robbins, P., Pavlos, N., Wysocki, S., Kumta, S. M., Wood, D. & Papadimitriou, J., 2000, In : Human Pathology. 31, 7, p. 804-812

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factors
Giant Cell Tumor of Bone
Vascular Endothelial Growth Factor A
Gene Expression
Osteoclasts