Jiake Xu

Winthrop Professor, MB BS Guangzhou, PhD W.Aust.

  • The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth


Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile


Dr Jiake Xu is currently Adjunct Professor. He was Winthrop Professor, Head of Molecular Laboratory, School of Biomedical Science, at the University of Western Australia (2011-2023). He served as Head of the Division of Regenerative Medicine (2017-2021). 

He is also a founding Fellow, Faculty of Science, the Royal College of Pathologists of Australia, Fellow of American Society of Bone and Mineral Research (ASBMR); Fellow of International Orthopedic Research (FIOR), and ex-president of the Australian and New Zealand Orthopaedic Research Society (ANZORS, 2012-2015).

He finished his medical training in Guangzhou Medical College in China in 1985. After completing his PhD studies at UWA in 1994, he carried out his postdoctoral research at Stanford University from 1994 to 1998. He returned to UWA in 1998, and has since undertaken research and teaching in the Schools of Surgery and Pathology and Laboratory Medicine.

His current research activities are focused on molecular cross talks of osteoclast and osteoblast, bone marrow stem cell niche (HSC, MSC, EPC), as well as angiogenic and angiocrine dysregulation, which have significant implication in bone and joint diseases; including osteoporosis, osteoarthritis and cancer metastasis in bone.

Roles and responsibilities

Prof Xu serves as a scientific program committee member for the Australian and New Zealand Orthopaedic Research Society (ANZORS), and as an elected member of the Board of Directors for the International Chinese Hard Tissue Society (ICHTS) since 2005. He also serves as a committee member in the Research Committee of the Australian and New Zealand Bone and Mineral Society (ANZBMS).

Funding overview

From 2000 to 2023 received
20 NHMRC as a chief investigator
1 ARC as a chief investigator


• Osteoimmunology, osteolysis, and mechanisms of bone resorption.
• Bone marrow-derived mesenchymal stem cells and pericytes
• Screening of natural compounds for the treatment of osteoporosis
• Deciphering the molecular basis of musculoskeletal diseases using ENU-induced mutant mice and cc mice
• Intercellular communication and angiogenic potential of endothelial progenitor cells in bone microenvironment

Teaching overview

Teaching and/or teaching Coordinator for

PATH2210 (Coordinator and teaching)

IMED3001, 3002, 3003, 3004

DENT3001, 3002, 3003, 3004



Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 14 - Life Below Water

Research expertise keywords

  • Bone biology
  • Degenerative diseases
  • Molecular biology and pathogenesis of bone disease


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