Research output per year
Research output per year
Personal profile
Biography
I completed my PhD degree in nanotechnology at the University of Western Australia, spending part of my doctoral studies as a Fulbright Scholar at the University of Massachusetts, Amherst (2018). My PhD focused on the design and evaluation of new materials for the delivery of gene therapeutics. From there, I was an Alexander von Humboldt Postdoctoral Fellow at the Technical University of Munich, where I worked on the design and implementation of DNA origami for biotechnological applications (2020 – 2022) with Prof Hendrik Dietz. I am now a Forrest Fellow, and I aim to establish DNA origami as a field of research within Western Australia.
Current projects
- DNA-based nano-sensors
- DNA origami for targeted gene and drug delivery
- Templated inorganic nanoparticle synthesis
- Cellular recognition and fate of DNA origami
- Assembly kinetics of nucleic acid nanostructures
Research interests
I model, build, and apply nanoscale interactions for applications such as biosensing and to improve delivery of drug and gene therapies. My research focus is based on designing and implementing bioengineered polymers and nanosystems for application in health, energy, and the environment. As such, my research interests and educational background are highly interdisciplinary.
Previous positions
|
02.2020 – 06.2022 |
Alexander von Humboldt Postdoctoral Fellow, Technische Universität München. Engineering complex DNA origami structures for biomedical applications. |
|
08.2019 – 01.2020 |
Research Assistant, Epigenetics and Genomics, Harry Perkins Institute of Medical Research. Used genome and epigenome engineering techniques to determine the roles and effects of multiplexed epimodifiers on cellular gene expression and epigenetic landscape. |
|
07.2018 – 03.2019 |
Fulbright Scholar, University of Massachusetts, Amherst. Protein engineering, production, and synthesis, and then design of polymeric agents for the non-viral delivery of proteins. |
|
06.2015 – 08.2019 |
Doctoral Candidate, The University of Western Australia and Harry Perkins Institute of Medical Research. Developing non-viral agents to deliver genome engineering technology for triple negative breast cancers in vitro and in vivo. |
|
12.2014 – 06.2015 |
Research Assistant, School of Molecular Sciences, The University of Western Australia. Laboratory organisation and setting up and implementing new systems such as a detailed inventory, in addition to driving individual projects. |
|
02.2014 – 07.2016 |
Laboratory Demonstrator, School of Molecular Sciences, The University of Western Australia. Teaching and assessing first year undergraduate chemistry students in the practical setting for the unit “CHEM1001 Chemistry – Properties and Energetics” |
|
02.2014 – 11.2014 |
Honours Research, The University of Western Australia. Engineering different polymer architectures for gene delivery. |
|
02.2013 – 11.2013 |
Undergraduate Research with F. Wood, The University of Western Australia and Fiona Wood Foundation. Establishing an in vitro scar model, and development of a polymeric nanoparticle system for the encapsulation of anti-fibrotic drugs. |
Fingerprint
Dive into the research topics where Jessica Kretzmann is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Single-cell RNA sequencing profiles drug activity within spatially engineered 3D cultures
King, J., Mowla, A., Kretzmann, J., Bhalla, N., Norret, M., Kadolsky, U., Iqbal, M., Saxena, A., Amos, S., Choi, Y. S., Kennedy, B., Swaminatha, I., Evans, C. & Smith, N., Dec 2026, In: Nature Communications. 17, 1, 7735.Research output: Contribution to journal › Article › peer-review
Open Access -
Human genomic DNA is widely interspersed with i-motif structures
Martinez , C. D. P., Zeraati, M., Rouet, R., Mazigi, O., Henry, J., Gloss, B. S., Kretzmann, J., Evans, C., Ruggiero, E., Zanin, I., Marušič, M., PLAVEC, J., RICHTER, S., Bryan, T., Smith, N., Dinger, M. E., Kummerfeld, S. & Christ, D., 15 Oct 2024, In: The EMBO Journal. 43, 20, p. 4786-4804 19 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Link opens in a new tab Citations (Scopus) -
Active Nuclear Import of Mammalian Cell-Expressible DNA Origami
Liedl, A., Grießing, J., Kretzmann, J. A. & Dietz, H., 8 Mar 2023, In: Journal of the American Chemical Society. 145, 9, p. 4946-4950 5 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Link opens in a new tab Citations (Scopus) -
Biocompatible dendronised polymer as a non-viral transfection agent
Iyer, K. S. (Inventor), Norret, M. (Inventor), Kretzmann, J. (Inventor) & Ho, D. (Inventor), 19 Sept 2023, IPC No. C08F 220/ 20 A I, Patent No. US2019077897, Priority date 13 Sept 2017, Priority No. AU20170903723Research output: Patent
-
Gene-encoding DNA origami for mammalian cell expression
Kretzmann, J. A., Liedl, A., Monferrer, A., Mykhailiuk, V., Beerkens, S. & Dietz, H., 23 Feb 2023, In: Nature Communications. 14, 1, p. 1017 1017.Research output: Contribution to journal › Article › peer-review
Open Access80 Link opens in a new tab Citations (Scopus)
-
Multipronged neurotrophin delivery strategies to restore proteostasis and bioenergetics
Kretzmann, J. (Investigator 01)
NHMRC National Health and Medical Research Council
1/07/26 → 30/06/27
Project: Research
-
ROBUST (RNA Optimisation for Biological Utility and STability)
Fox, A. (Investigator 01), Bond, C. (Investigator 02), Ward, M. (Investigator 03), Kretzmann, J. (Investigator 04), Conn, S. (Investigator 05), Carlessi, R. (Investigator 06), Wylie, B. (Investigator 07), Lesterhuis, W. (Investigator 08), Shirokikh, N. (Investigator 09), Beilharz, T. (Investigator 10), Cooper, C. (Investigator 11), Swain, T. (Investigator 12), Shimoni, O. (Investigator 13) & Corbin, V. (Investigator 14)
MRFF Medical Research Future Fund
30/06/26 → 31/12/30
Project: Research
-
DNA origami nanostructures for iPSC generation and cell reprogramming
Kretzmann, J. (Investigator 01)
NHMRC National Health and Medical Research Council
1/01/26 → 31/12/30
Project: Research
-
Core Freeze Drying and Concentrating Platform to Support Biomedical Research
Flematti, G. (Chief Investigator), Chooi, H. (CoPI), Fox, A. (CoPI), Geddes, D. (CoPI), Kretzmann, J. (CoPI), Lister, R. (CoPI), Pfleger, K. (CoPI), Piggott, M. (CoPI), Smith, N. (CoPI) & Swaminatha Iyer, I. (CoPI)
1/01/26 → 31/12/26
Project: Research
-
Engineering the intracellular fate of DNA origami
Kretzmann, J. (Investigator 01)
ARC Australian Research Council
1/08/25 → 31/07/28
Project: Research
Prizes
-
-
2025 Early Career Scientist of the Year
Kretzmann, J. (Recipient), 17 Nov 2025
Prize: W.A. Premier’s Science Award
-
-
Women in Technology WA (WiTWA) STEM Academia and Research Rising Star Award
Kretzmann, J. (Recipient), 2023
Prize: Award
-
-
Sausages and Science
Taylor, N. (Coordinator), Kretzmann, J. (Coordinator), Rae, K. (Coordinator), Kyrwood, C. (Coordinator), Lee, K. H. (Mentor), Roman, G. (Mentor), Chandrasekaran, K. (Mentor), McCabe, E. (Mentor), Bhalla, N. (Mentor), Katoch, S. (Mentor), Evans, K. (Mentor), Sagar, G. (Mentor), Waters, M. (Mentor), Kuhar, T. (Coordinator), Al-Obaidi, L. (Coordinator), Holder, S. (Coordinator), Rubim Silva do Couto, R. (Mentor), Mern, M. (Mentor) & Low, P. (Advisor)
26 Apr 2024 → …Activity: Service and engagement › Public outreach/ public event
-
DNA Origami Workshop 2023
Evans, C. (Participant) & Kretzmann, J. (Organiser)
14 Nov 2023Activity: Conferences and workshops › Participation in workshop, seminar or course
-
Molecules, Models, and Morsels: Engaging Indigenous Youth in the Wonders of Science
Taylor, N. (Coordinator), Wheat, N. (Coordinator), Evans, C. (Coordinator), Kretzmann, J. (Coordinator), Swaminatha Iyer, K. (Coordinator) & Low, P. (Mentor)
3 Apr 2023 → …Activity: Service and engagement › Public outreach/ public event
File
Courses
Press/Media
-
Top Indigenous STEM students make finals of Premier's Science Awards
Freshwater, D., Kretzmann, J., Martin, B. C., Jiang, H. & Bayer, P.
21/06/19
1 item of Media coverage
Press/Media: Press / Media