• The University of Western Australia (M310), 35 Stirling Highway,

    6009 Perth


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Personal profile


I completed my PhD degree in nanotechnology at the University of Western Australia, spending part of my doctoral studies as a Fulbright Scholar at the University of Massachusetts, Amherst (2018). My PhD focused on the design and evaluation of new materials for the delivery of gene therapeutics. From there, I was an Alexander von Humboldt Postdoctoral Fellow at the Technical University of Munich, where I worked on the design and implementation of DNA origami for biotechnological applications (2020 – 2022) with Prof Hendrik Dietz. I am now a Forrest Fellow, and I aim to establish DNA origami as a field of research within Western Australia.

Current projects

  • DNA-based nano-sensors
  • DNA origami for targeted gene and drug delivery
  • Templated inorganic nanoparticle synthesis
  • Cellular recognition and fate of DNA origami
  • Assembly kinetics of nucleic acid nanostructures

Research interests

I model, build, and apply nanoscale interactions for applications such as biosensing and to improve delivery of drug and gene therapies.  My research focus is based on designing and implementing bioengineered polymers and nanosystems for application in health, energy, and the environment. As such, my research interests and educational background are highly interdisciplinary.

Previous positions

02.2020 – 06.2022

Alexander von Humboldt Postdoctoral Fellow, Technische Universität München. Engineering complex DNA origami structures for biomedical applications.

08.2019 – 01.2020

Research Assistant, Epigenetics and Genomics, Harry Perkins Institute of Medical Research. Used genome and epigenome engineering techniques to determine the roles and effects of multiplexed epimodifiers on cellular gene expression and epigenetic landscape.

07.2018 – 03.2019

Fulbright Scholar, University of Massachusetts, Amherst. Protein engineering, production, and synthesis, and then design of polymeric agents for the non-viral delivery of proteins.

06.2015 – 08.2019

Doctoral Candidate, The University of Western Australia and Harry Perkins Institute of Medical Research. Developing non-viral agents to deliver genome engineering technology for triple negative breast cancers in vitro and in vivo.

12.2014 – 06.2015

Research Assistant, School of Molecular Sciences, The University of Western Australia. Laboratory organisation and setting up and implementing new systems such as a detailed inventory, in addition to driving individual projects.

02.2014 – 07.2016

Laboratory Demonstrator, School of Molecular Sciences, The University of Western Australia. Teaching and assessing first year undergraduate chemistry students in the practical setting for the unit “CHEM1001 Chemistry – Properties and Energetics”

02.2014 – 11.2014

Honours Research, The University of Western Australia. Engineering different polymer architectures for gene delivery.

02.2013 – 11.2013

Undergraduate Research with F. Wood, The University of Western Australia and Fiona Wood Foundation. Establishing an in vitro scar model, and development of a polymeric nanoparticle system for the encapsulation of anti-fibrotic drugs.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being


Dive into the research topics where Jessica Kretzmann is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years

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