Research Output per year
Personal profile
Biography
I obtained my PhD under the supervision of Professor Timothy Arnett at University College London, investigating the effects of hypoxia on bone cells, including osteoclasts and osteoblasts. I have held post-doctoral positions at University College London, the University of Surrey, and the University of Western Australia studying the cell biology of bone marrow, bone cells and underlying physiological and genetic regulators of bone cell activity and function. My current research interests focus on identification of novel genetic regulators of bone cell function utilising mouse models.
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Osteoclasts
Medicine & Life Sciences
Bone
Chemical Compounds
Osteogenesis
Medicine & Life Sciences
Bone Resorption
Medicine & Life Sciences
Bone and Bones
Medicine & Life Sciences
Osteoporosis
Medicine & Life Sciences
Chemical activation
Chemical Compounds
Osteoblasts
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2005 2019
Advanced Genetic Approaches in Discovery and Characterization of Genes Involved With Osteoporosis in Mouse and Human
Yuan, J., Tickner, J., Mullin, B. H., Zhao, J., Zeng, Z., Morahan, G. & Xu, J., 2 Apr 2019, In : Frontiers in Genetics. 10, 13 p., 288.Research output: Contribution to journal › Review article
Open Access
Asiaticoside, a component of Centella asiatica attenuates RANKL-induced osteoclastogenesis via NFATc1 and NF-kappa B signaling pathways
He, L., Hong, G., Zhou, L., Zhang, J., Fang, J., He, W., Tickner, J., Han, X., Zhao, L. & Xu, J., Apr 2019, In : Journal of Cellular Physiology. 234, 4, p. 4267-4276 10 p.Research output: Contribution to journal › Article
Cajaninstilbene acid inhibits osteoporosis through suppressing osteoclast formation and RANKL-induced signaling pathways
Sun, Y., Liu, Y., He, W., Wang, C., Tickner, J., Kuek, V., Zhou, C., Wang, H., Zou, X., Hong, Z., Yang, F., Shao, M., Chen, L. & Xu, J., 1 Jul 2019, In : Journal of Cellular Physiology. 234, 7, p. 11792-11804 13 p.Research output: Contribution to journal › Article
Osteoclasts
Osteoporosis
Bone
Bone and Bones
Osteogenesis
1
Citation
(Scopus)
Cumambrin A prevents OVX-induced osteoporosis via the inhibition of osteoclastogenesis, bone resorption, and RANKL signaling pathways
Zhou, L., Liu, Q., Hong, G., Song, F., Zhao, J., Yuan, J., Xu, J., Tan, R. X., Tickner, J., Gu, Q. & Xu, J., 1 Jun 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 6, p. 6726-6735 10 p.Research output: Contribution to journal › Article
Osteoclasts
Bone Resorption
Osteogenesis
Osteoporosis
Bone
Evodiamine inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice
Jin, H., Yao, L., Chen, K., Liu, Y., Wang, Q., Wang, Z., Liu, Q., Cao, Z., Kenny, J., Tickner, J., Wang, X. & Xu, J., Jan 2019, In : Journal of Cellular and Molecular Medicine. 23, 1, p. 522-534 13 p.Research output: Contribution to journal › Article
Open Access
Ovariectomy
Osteogenesis
Bone and Bones
Osteoclasts
Postmenopausal Osteoporosis
Projects 2012 2022
‘Sorting-Out’ the molecular link between SNX10 and Autophagy in Osteoclasts
Xu, J., Pavlos, N. & Tickner, J.
National Health & Medical Research Council NHMRC
1/01/19 → 31/12/22
Project: Research
Gene mining for novel molecular determinants of the skeleton
Xu, J., Pavlos, N., Tickner, J., Wilson, S. & Walsh, J.
National Health & Medical Research Council NHMRC
1/01/17 → 31/12/19
Project: Research
Furin: Carving-up vital substrates for bone remodelling and homeostasis
Xu, J., Pavlos, N. & Tickner, J.
National Health & Medical Research Council NHMRC
1/01/16 → 31/12/19
Project: Research
2017 - The iCelligence system
Xu, J., Pavlos, N., Tickner, J., Meehan, K., Mullin, B. & Jiang, H.
National Health & Medical Research Council NHMRC
1/01/18 → 31/12/18
Project: Research
Identification of novel molecules that regulate bone homeostasis using ENU-induced mutant mice models, and human genome-wide association studies and massive parallel sequencing
Tickner, J., Wilson, S., Mullin, B., Xu, J., Leo, P., Duncan, E. & Brown, M.
University of Western Australia
1/01/15 → 31/12/15
Project: Research