Jasreen Kular

Dr Kular completed her undergraduate (2007) and PhD studies (2012) at the University of Western Australia. Her PhD research focused on discovering novel regulators of bone homeostasis that could be translated into therapeutic targets for osteoporosis, arthritis, and Paget’s disease of bone. In 2013, Dr Kular commenced a postdoctoral position at the Centre for Cancer Biology, Adelaide in the laboratory of Professor Michael Samuel. Her work identified 14-3-3ζ as a novel negative regulator of mechano-reciprocity which limits epidermal regeneration, potentially halving the healing time for chronic wounds. Dr Kular moved back to Perth and joined The Kids Research Institute Australia in 2022, bringing her skills in cell biology and cell signalling pathways to Group A Streptococcus (GAS) research (Dr Tim Barnett’s Laboratory). Her research used microscopy techniques to elucidate how GAS invades cells to evade antibiotic treatment. She continues to be involved in GAS research through her Honorary position at The Kids Research Institute. In 2024 Dr Kular returned to research in bone biology at the University of Western Australia in the laboratory of A/Prof Nathan Pavlos. She continues her work to understand the molecular mechanisms of bone-resorbing osteoclasts, particularly the regulation of intracellular trafficking, to identify novel therapeutic targets for debilitating musculoskeletal diseases including osteoporosis, osteoarthritis and Paget’s disease.