Research output per year
Research output per year
Personal profile
Biography
Associate Professor Jason Waithman leads the Cancer Immunotherapy Program within the School of Biomedical Sciences at the University of Western Australia. He is an expert in the field of dendritic cell biology and T cell immunity, with extensive experience in conceiving and applying a versatile range of tools for studying immunity to cancer, viral infections and self-tissue. This has resulted in significant practical and conceptual contributions to our understanding of health and disease. These models are now routinely used to facilitate translational outcomes into the clinical pipeline and pathway for potential commercialisation. More recently, this toolkit has been expanded to leverage advanced genomic data science, integrating this capacity across multiple projects focussed on identifying novel therapeutic targets to inform on improved strategies for cancer control within the community.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Immunology, PhD, Mechanisms of CD8 T cell tolerance, University of Melbourne
Award Date: 27 Aug 2008
Research expertise keywords
- Immunology—cellular
- Immunology—T cell
- immune tolerance
- Cancer immunology
- Immune cell signalling
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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CD4+ T cell immunity against cutaneous melanoma encompasses multifaceted MHC II-dependent responses
Bawden, E. G., Wagner, T., Schröder, J., Effern, M., Hinze, D., Newland, L., Attrill, G. H., Lee, A. R., Engel, S., Freestone, D., de Lima Moreira, M., Gressier, E., McBain, N., Bachem, A., Haque, A., Dong, R., Ferguson, A. L., Edwards, J. J., Ferguson, P. M. & Scolyer, R. A. & 10 others, , 19 Jan 2024, In: Science immunology. 9, 91, p. eadi9517 adi9517.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Transcriptional rewiring in CD8+ T cells: implications for CAR-T cell therapy against solid tumours
Srinivasan, S., Armitage, J., Nilsson, J. & Waithman, J., 2024, In: Frontiers in Immunology. 15, 20 p., 1412731.Research output: Contribution to journal › Review article › peer-review
Open Access -
Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years
Read, J. F., Serralha, M., Armitage, J. D., Iqbal, M. M., Cruickshank, M. N., Saxena, A., Strickland, D. H., Waithman, J., Holt, P. G. & Bosco, A., 2023, In: Frontiers in Immunology. 14, 1275937.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells
Barrett, L. W., Fear, V. S., Foley, B., Audsley, K., Barnes, S., Newnes, H., McDonnell, A., Wood, F. M., Fear, M. W. & Waithman, J., 2022, In: Burns and Trauma. 10, tkac016.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Web of Science) -
Tissue-resident memory T cells in the era of (Neo) adjuvant melanoma management
Plunkett, K. R., Armitage, J. D., Inderjeeth, A. J., McDonnell, A. M., Waithman, J. & Lau, P. K. H., 16 Nov 2022, In: Frontiers in Immunology. 13, 1048758.Research output: Contribution to journal › Review article › peer-review
Open Access8 Citations (Scopus)
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Lionheart FX Automated High-Content Microscope for the QEII Biomedical Research Precinct
Barnett, T. (CoPI), Blancafort, P. (CoPI), Chen, K. (CoPI), Chooi, H. (CoPI), Hamzah, J. (CoPI), Hirvonen, L. (CoPI), Ingley, E. (CoPI), Johnstone, L. (CoPI), Kahler, C. (CoPI), Keelan, J. (CoPI), Kular, J. (CoPI), Mullin, B. (CoPI), Nicol, M. (CoPI), Pixley, F. (CoPI), Swaminatha Iyer, I. (CoPI), Waithman, J. (CoPI), Wilson, S. (CoPI) & Woodward, E. (CoPI)
The University of Western Australia
1/01/25 → 31/12/25
Project: Research
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Enhancing natural killer cell function to combat high-risk B-ALL with Tri-specific Killer Engagers (TriKEs)
Foley, B. (Investigator 01), Armitage, J. (Investigator 02), Malinge, S. (Investigator 03) & Waithman, J. (Investigator 04)
1/01/25 → 31/12/25
Project: Research
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Establishing TIL therapy For Immunotherapy-Resistant Melanoma
Nilsson, J. (Investigator 01), Gray, E. (Investigator 02), Waithman, J. (Investigator 03) & Lau, P. (Investigator 04)
1/04/24 → 31/12/28
Project: Research
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Enhancing adoptive cell therapy protocols to improve childhood and adolescent cancer control
Lister, R. (Investigator 01), Darcy, P. (Investigator 02), Beavis, P. (Investigator 03), Khaw, S. (Investigator 04), Velickovic, Z. (Investigator 05), Bosco, A. (Investigator 06), Armitage, J. (Investigator 07), Pflueger, C. (Investigator 08), Foley, B. (Investigator 09), Carnley, B. (Investigator 10), Wood, M. (Investigator 11), Woulfe, C. (Investigator 12), Herring, C. (Investigator 13) & Waithman, J. (Investigator 14)
Department of Health (Western Australia)
1/01/24 → 31/12/25
Project: Research
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Redox imbalance as a driver and therapeutic target for acute lymphoblastic leukaemia
Kenny, J. (Investigator 01), Sayin, V. (Investigator 02), Waithman, J. (Investigator 03), Lister, R. (Investigator 04), Pflueger, C. (Investigator 05) & Cruickshank, M. (Investigator 06)
Department of Health (Western Australia)
1/01/23 → 1/01/26
Project: Research