Personal profile
Biography
Professor Jason Kovacic is the Executive Director of the Victor Chang Cardiac Research Institute and Adjunct Professor at the University of Western Australia. He graduated from The University of Melbourne Medical School in 1994, and then undertook residency and cardiology specialty training in interventional cardiology at St Vincent's Hospital in Sydney, becoming a Fellow of The Royal Australasian College of Physicians in 2003. Prof Kovacic then completed a PhD in cardiovascular medicine at the Victor Chang Cardiac Research Institute.
In 2007, he was elected as a Fellow of The American College of Cardiology and relocated to the USA, to the National Heart, Lung and Blood Institute (NHLBI) at the National Institutes of Health (NIH) in Bethesda, Maryland. At the NIH, Professor Kovacic discovered critical new pathways that lead to blockage of the body's blood vessels. He then moved to The Icahn School of Medicine at Mount Sinai in New York. In parallel with his vital ongoing research to define new ways to prevent and treat vascular disease, Jason is a practicing clinical cardiologist, specializing in vascular disease and blockages of the heart arteries.
Professor Kovacic has authored numerous scientific and clinical papers on heart and vascular disease and serves on a number of NIH committees. He has a particular interest in unraveling the pathobiology of the vascular diseases, fibromuscular dysplasia and spontaneous coronary artery dissection.
He is also President-Elect of the Australian Cardiovascular Alliance.
In addition to his many achievements in medicine and in biomedical research, Professor Kovacic was an elite athlete, having been a world-class rower, plays classical guitar and speaks several languages.
Research expertise keywords
- PHACTR1
- gene networks
- cardiovascular progenitor cell
- coronary artery disease
- atherosclerosis
- vascular disease
- fibromuscular dysplasia
- spontaneous coronary artery dissection
- genetic mechanisms underlying heart disease
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Collaborations and top research areas from the last five years
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Endothelial to mesenchymal transition in cardiovascular diseases: molecular insights and clinical perspectives
Hall, I. F., Aikawa, E., Sluimer, J., Baker, A. H. & Kovacic, J. C., 7 Mar 2026, In: European Heart Journal. 47, 10, p. 1144-1158 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Endothelial to mesenchymal transition, Ets2 and the aging heart
Hall, I. F., Kishta, F. & Kovacic, J. C., 1 Dec 2025, In: Cardiovascular Research. 121, 18, p. 2820-2821 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Environmentally Not So Friendly: Global Warming, Air Pollution, and Wildfires: JACC Focus Seminar, Part 1
Miller, M. R., Landrigan, P. J., Arora, M., Newby, D. E., Münzel, T. & Kovacic, J. C., 11 Jun 2024, In: Journal of the American College of Cardiology. 83, 23, p. 2291-2307 17 p.Research output: Contribution to journal › Review article › peer-review
33 Link opens in a new tab Citations (Scopus) -
The national Cardiovascular Health Leadership Research Forum: a new data-driven model placing research at the centre of improving patient outcomes
Cardiovascular National Health Leaders Research Forum Writing Group & Nedkoff, L., 4 Nov 2024, In: Medical Journal of Australia. 221, 9, p. 452-456 5 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Citation (Scopus) -
Water, Soil, Noise, and Light Pollution: JACC Focus Seminar, Part 2
Miller, M. R., Landrigan, P. J., Arora, M., Newby, D. E., Münzel, T. & Kovacic, J. C., 11 Jun 2024, In: Journal of the American College of Cardiology. 83, 23, p. 2308-2323 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access10 Link opens in a new tab Citations (Scopus)