Henry Hui

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Henry Hui

Dr, BSc BMedSci PhD W.Aust., Early Career Researcher in the Translational Cancer Pathology Laboratory

 https://orcid.org/0000-0002-0442-6987

  • The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth

    Australia

Accepting PhD and other Higher Degree by Research Students. View current PhD/HDR research project opportunities at https://researchdegrees.uwa.edu.au/projects

Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile

Biography

I am a highly passionate early career research associate and emerging global leader in the development of advanced cell analysis technology and cutting-edge methodologies for both research and clinical applications. My work enables me to charter new frontiers in technology to advance knowledge and generate technical solutions to challenges in science, health and medicine. My vision is a world where no child or adult dies from a cancer that was missed or mischaracterised.

Since 2013, I have had a key role in the expansion of an award-winning, multi-disciplinary research team that leads the world in imaging flow cytometry powered diagnostic developments for haematological malignancies and constitutional disorders in adults, children and neonates. I am the co-inventor of the world-first “Immuno-flowFISH” method, a game-changing diagnostic technology. This invention enables precision assessment of blood cancers that vastly exceeds current research and clinical testing modalities. In 2018, I was awarded the highly prestigious ANSTO 2018 Eureka Prize for Innovative Use of Technology by the Australian Museum.

My research has patented in many countries and my world-leading expertise has drawn investment and funding equivalent to $4.7M in value from industry partnerships, government grants and health-care organisations. I have published in high-impact journals, written book chapters and been invited to speak at national and international conferences. I also hold leadership and advisory roles with ISAC and ACS. Currently, I have global multidisciplinary collaborative networks that intersect research, clinical and industry commercialisation pipelines. This includes both industry leading medical technology corporations (Sysmex Corporation, Empire Genomics, KromaTID & Cytek Biosciences), world-class diagnostic cancer centres (MD Anderson Cancer Centre, Roswell Park Cancer, University of Cambridge), clinical research groups (University of Oxford) and international government agencies (US National Institute of Standards and Technology).

I am currently leading the translation of immuno-flowFISH through this multi-disciplinary collaborative network to establish global adoption of this technology. My long-term goal as a scientist is to lead the innovation, application, education, and outreach of medical research in both scientific and clinical domains, to advance knowledge and health globally.

Above all else, I strive to provide a tangible hope for a cure for patient and their families through equitable access to advanced, precision diagnostics.

Research

Prizes and Awards

2025 WA FHRI Emerging Leader Award

2022 Raine Priming Grant

2021 Raine BrightSpark Research Collaboration Award

2021 Cancer Council Western Australia Early Career Researcher of the Year

2021 Marylou Ingram Scholar, International Society for Advancement of Cytometry (25 in the world)

2020 Laurence Catley Best Abstract Award at the 3rd National Myeloma Workshop Australia

2018 Australian Museum ANSTO Eureka Prize for Innovative Use of Technology

2018 UWA Innovation Quarter (IQ) Research Innovation and Enterprise Award

2018 “Top 20 PhD” student shortlist for the CSL Florey Award, Australian Institute of Policy and Science

2017 Travel Award, Australian Cytometry Society for CYTO Asia

2016 Travel Award from the International Society for Advancement of Cytometry

2016 University Postgraduate Award, University of WesternAustralia

2014 Runner Up, best presentation at the Students in Health and Medical Research conference

Roles and responsibilities

Teaching, Professional Leadership, Editorial Roles, and Governance

2025 Guest Editor, Cytometry Part A Special Issue

2024–current: Co-Chair, CYTO-Connect Congress, Perth 2025

2024– Associate Lecturer, Medical Science and Genetics; Pathology (IMED 1003 & 1004; PATH2221 PATH3309), UWA

2021–current: ISAC Mary Lou Ingram Scholar and Image Cytometry Education Subcommittee

2021–current: Executive Secretary and Councillor, Australasian Cytometry Society

2020–2021: State Committee Member, Australian Society for Medical Research (ASMR WA)

2021– Research Associate, Translational Cancer Pathology Laboratory, UWA

2019 - 2021 Post-doctoral Research Scientist, Translational Cancer Pathology Laboratory, UWA

Funding overview

WA Department of Health Near-Miss Emerging Leader Award (2025; AU $100 000)

“A New Test to Identify High-Risk Childhood Leukaemia”. CIC. The Channel 7 Telethon Trust 2025-2026. $246,270.

“A Pathway to Leukaemia Prevention” Research Innovation and Impact Grant 2025-2027 (RPH Research Foundation / WA Future Health Research & Innovation Fund). CID: $1,147,285

"Precision Diagnostics for Blood Cancers" Future Health Research and Innovation Fund 2022-2024. (Department of Health, Government of Western Australia). CIC. $499,632.

"Developing a user-friendly machine learning enabled diagnostic tool for paediatric acute lymphoblastic leukaemia (ALL)" UWA Research Collaboration Awards 2022 (The University of Western Australia). CIC: $20,000.

"Next-Generation Single Cell Diagnostics of Blood Cancers" Raine Priming Grant 2022 (Raine Medical Research Foundation). CIA. $$224,649.

“Improving Survival in Childhood Leukaemia”. Chief Investigator A. Raine BrightSpark Research Collaboration Award 2022 (Raine Medical Research Foundation). $29,864.

“Precision molecular diagnostics of single cells by imaging flow cytometry”. CIC. National Health and Medical Research Council (NHRMC) Ideas grant 2021. $875,110.

“Conquering Chronic Leukaemia in Children”. CIC. The Channel 7 Telethon Trust. $124,000.

“Putting a new lens on childhood leukaemia”. CIC. The Channel 7 Telethon Trust. $100,000.

“Detecting high risk chromosomal aberrations in patients with myeloproliferative neoplasms using automated imaging flow cytometry for prognostication” CIF. Spinnaker Health Research Foundation. $14,775.

Research

Publications (Journal Articles & Book Chapters)

  1. Power H, O’Brien MJ, Takahashi M, Hui H, Fuller K, Korbie D, Berry O, Jarman S. Isolation and Genetic Identification of Metazoan Cells From Seawater. Environmental DNA. 2025;7:e70154. doi:10.1002/edn3.70154.
  2. Buic D, Lama S, Hui HYL, George C, Yong ASM, Kotecha RS, Erber WN, Fuller KA. Flow cytometric detection of BCR::ABL1 in T-lymphocytes in chronic myeloid leukaemia. Pathology. 2025;57:650-654. doi:10.1016/j.pathol.2025.03.004.
  3. Simpson APA, George CE, Hui H, Doddi R, Kotecha RS, Fuller KA, Erber WN. Imaging Flow Cytometric Identification of Chromosomal Defects in Paediatric Acute Lymphoblastic Leukaemia. 2025;14(2):114.
  4. King JJ, Chen K, Evans CW, Norret M, Almasri R, Pavlos NJ, Hui H, Lin Q, Bhatt U, Young SG, Smith NM, Nikan M, Prestidge CA, Jiang H, Iyer KS. High-resolution visualisation of antisense oligonucleotide release from polymers in cells. Chemical Science. 2024;15(38):15690–15697.
  5. Mincherton T, Lam SJ, Clarke S, Hui H, Malherbe J, Chuah H, Sidiqi MH, Fuller KA, Erber WN. Imaging flow cytometric detection of del(17p) in bone marrow and circulating plasma cells in multiple myeloma. International Journal of Laboratory Hematology. 2024;46(3):495–502
  6. Ramesh P, Hui H, Brownrigg LM, Fuller KA. & Erber, WN. Chimeric antigen receptor T-cells: Properties, production, and quality control. International Journal of Laboratory Hematology. 2023; 45, 4, 425-435.
  7. Erber, WN, Hui H, Mincherton T, Harms M, Clarke S. & Fuller KA. Enhanced multi-FISH analysis of immunophenotyped plasma cells by imaging flow cytometry. Journal of Human Genetics. 2023; 68, 7, 515-516.
  8. Hui H, Fuller KA, Jaya LE, Konishi Y, Ng TF, Frodsham R, Speight G, Yamada K, Erber WN. IGH Cytogenetic Abnormalities Can be Detected in Multiple Myeloma by Imaging Flow Cytometry. Journal of Clinical Pathology. 2023; Nov;76(11):763-769.
  9. Lam S*, Mincherton T*, Hui H, Fuller KA, Sidiqi H, Erber WN. Imaging Flow Cytometry shows Monosomy 17 in Circulating Plasma Cells in Myeloma. Pathology. 2022.
  10. Hui H, Stanley J, Fuller KA, Clarke KM, Erber WN. Multi-probe FISH Analysis of Immunophenotyped Chronic Lymphocytic Leukaemia by Imaging Flow Cytometry. Current Protocols. 2021; 1(10):e260.
  11. Stanley J, Hui H, Erber W, Clynick B, Fuller K. Analysis of human chromosomes by imaging flow cytometry. Cytometry Part B. Clinical Cytometry. 2021; 100: 541-553.
  12. Erber W, Hui H, Stanley J, Mincherton T, Clarke K, Augustson B, Ng T, Cheah C, McQuillan A, Fuller K. Detection of Del(17p) in Hematological Malignancies By Imaging Flow Cytometry. Blood. 2020; 136: 9-10. (Published abstract from the American Society of Haematology 2020 conference proceedings).
  13. Hui H, Clarke KM, Fuller KA, Stanley J, Chuah H, Ng TF, Cheah C, McQuillan A, Erber WN. “Immuno- flowFISH” for the assessment of cytogenetic abnormalities in chronic lymphocytic leukemia. Cytometry Part A (special edition). 2019; 95(5): 521-533.
  14. Hui H, Fuller KA, Chuah H, Liang J, Sidiqi H, Radeski D, Erber WN. Imaging flow cytometry to assess chromosomal abnormalities in chronic lymphocytic leukaemia. Methods. 2018; 134-135:32-40.
  15. Hui H, Fuller KA, Erber WN, Linden MD. Imaging flow cytometry in the assessment of leukocyte-platelet aggregates. Methods. 2017; 112:46-54.
  16. Fuller KA, Bennett S, Hui H, Chakera A, Erber WN. Development of a Robust Immuno-S-FISH Protocol Using Imaging Flow Cytometry A. 2016; 89A: 720-30.
  17. Hui H, Fuller KA, Erber WN, Linden MD. Measurement of monocyte-platelet aggregates by imaging flow cytometry. Cytometry 2015 Mar; 87(3): 273-8.

Book Chapters

  1. Hui H, Erber WN, Fuller KA. "Immuno-FlowFISH": Applications for chronic lymphocytic leukemia. Methods in Molecular Biology. 2023; 2635:149-171.
  2. Lam S, Hui H, Fuller KA and Erber W. Assessing chromosomal abnormalities in leukemias by imaging flow cytometry. Flow Cytometry in Immuno-oncology. Methods in Cell Biology Elsevier, 2025

Oral Presentations at National/International Conferences (including peer-reviewed select abstracts)

2025   International Society for Advancement of Cytometry conference, USA (invited workshop/tutorial and oral presentation)

2024   5th Sino-US International Cytometry Workshop, China (invitation)

2021    Science Lands in Parliament, Parliament house, Western Australia

2021    International Society for Advancement of Cytometry conference, USA (inivation)

2020    3rd National Myeloma Workshop, Australia (best abstract award)

2020    Lorne Cancer Conference, Australia

2019; 2021    Blood Annual Scientific Meeting, Australia

2018; 2023    Australian Cytometry Society Annual Scientific Meeting, Australia (invitation 2023)

2017    CYTOAsia 2017, Singapore.

2015    Australasian Society of Medical Research national conference, Australia (prize awarded for presentation)

2014; 2019    Indian Ocean Rim Laboratory Haematology Congress, Australia

Industrial relevance

Industry or Government Engagement/Collaborations:

I have government and industry funded collaborations to develop novel diagnostic tests and medical technology to advance scientific knowledge and human health. I lead or provide consultation (both interllectual and technincal input) on the development, testing, data review and comercialisation in these goverment agency or industry networks:

2024 – Current KromaTID research collaboration – intellectual input, data review and development

2023 – Current Empire Genomics research collaboration – intellectual input, data review and development

2023 – Current Cytek Biosciences research collaboration – intellectual input, data review and development

2022- Current US National Institute of Standards and Technology (USA government) – intellectual input, training, data review and development

2020 – 2022   Luminex Corporation research collaboration – intellectual input, data review and development

2018 – 2014   SYSMEX Corporation research collaboration – intellectual input, data review and development

2019 – 2021   SCHOTT   Minifab research collaboration – consultation, intellectual input, data review

 

My work has been licensed and patented in multiple countries:

“Improvements in or relating to cell analysis” (WO/2019/079851) (PCT/AU2018/051148)

2020     Filed: USA US20200232019; China CN111448324; Europe EP2018870567

2024     Japan Patent JP7554472B2 (accepted)

2024     Australia Patent AU2018355889B2 (accepted)

USA (Standard) Patent US20200232019 – pending

Europe (Standard) Patent EP3701045 – pending

Research

Journal Editorials, Reviews and Thesis Examination

2025-   Cytometry Part A Special Edition co-guest editor- “Latest Progress in Single-Cell Imaging Technologies”

2025-   Pathology peer review for research manuscript

2022-   Cytometry Part A peer review for research manuscript

2020    PLOS ONE peer review for research manuscript

2019    Thesis examiner for Master of Clinical Pathology, University of Western Australia

2022    Thesis examiner for Honors in Biomedical Sciences, University of Western Australia

2013    Journal of the American College of Cardiologists (peer review with research supervisor)

Teaching overview

Student Teaching, Supervision, Training and Mentoring (UWA)

2025-   Lecturer & laboratory instructor for Pathology Units

2024-  Unit coordinator, lecturer and tutor  for IMED1003 & IMED1004 (health and cell biology units for Medicine)

2017-   Undergraduate and Masters units/majors in biomedical sciences (e.g. Pathology, microbiology, integrated medical sciences, medical genetics, molecular Pathology): IMED2001 Body defenses; MICR5842 Principles of Infection and Immunity; PATH3309 Cancer Pathology; PATH/IMED Drugs and Diseases (with Clayton Fragall  2016-2019); MCP Masters of Clinical Pathology (mentor for students undertaking "Humans of Haematology” or “Science journalism" Projects as an assignment of the Advanced Haematology unit)

2018- Honours, Masters and PhD (HDR) research projects: research training; supervision; mentoring; review of manuscripts and theses (2025 – supervising honours student)

2023- Advisory panel for HDR student (PhD) – project reviews and strategic input

Engagement

Wider Scientific Education & Engagement (Live, Virtual or Publicised):

2022- Hosted live education workshops/watch party for the Australian Cytometry Society (UWA/WA Cytometry hub)

2022- Published an online guide (Biotechniques) for a junior audience (Honours, PhD, Early Career level) to develop competency and proficiency in using cytometry technology for their research – “How to: life in the FACS lane of flow cytometry”: https://www.biotechniques.com/analytical- chemistry/how-to-life-in-the-facs-lane-of-flow-cytometry/

2023- National and international cytometry related news and media dissemination (via published online newsletters) for education, advocacy, policy, scientific meetings, workshops, webinars, and networking (Australian Cytometry Society); including profile management of the entire of membership of the organisation (>500)

2022- Abstract peer review (with feedback); poster and oral presentation adjudication; workshop and scientific presentation session chairing at national and international meetings

2023- Image Cytometry Subcommittee (Education) - oversees and develops International Society for the Advancement of Cytometry (ISAC) educational content in image cytometry and related medical technologies (including presenter program building and invitation to provide a workshop at CYTO 2024)

2023-2025- ACS/ISAC CYTO-Connect international Cytometry scientific meeting 2025 – Conference co-chair; strategic planning, program development, speaker and sponsor engagement and media dissemination

2016- Multidisciplinary training, consultation, mentoring and collaborative input in science, health, industry, and community (e.g. research scientists, clinical fellows, and technical staff) in diverse fields of haematology, immunology, respiratory medicine, micro-vesicle biomarkers, microbiology, marine biology, ecological conservation, bone pathology, neonatal/maternal health, and data science.

 

Publicised, media releases/community engagement, impact and outreach

  • https://fhrifund.health.wa.gov.au/News-and-Events/2025/04/07/Funding-injection-for-early-and-mid-career-researchers
  • https://impactreport.telethon7.com/2025/grant-recipients/?utm_source=sfmc&utm_medium=email&utm_campaign=Telethon+Diary+-+Giving+Edition&utm_content=https%3a%2f%2fimpactreport.telethon7.com%2f2025%2fgrant-recipients%2f&utm_id=129073&sfmc_id=27220342
  • https://www.rainefoundation.org.au/research-story/an-innovative-diagnostic-tool-for-children-with-high-risk-leukaemia/
  • https://www.uwa.edu.au/news/article/2025/april/telethon-funds-boost-child-health-projects-to-build-a-brighter-future
  • https://www.uwa.edu.au/news/article/2024/october/breakthrough-grant-to-enhance-leukaemia-detection-in-australia
  • https://www.rainefoundation.org.au/2022-grants-fellowships-awards-and-prizes-announcement/
  • https://www.biotechniques.com/analytical-chemistry/how-to-life-in-the-facs-lane-of-flow-cytometry/
  • https://fhrifund.health.wa.gov.au/News-and-Events/2022/07/03/Major-early-stage-health-and-medical-innovation-funding-announced
  • https://www.cancerwa.asn.au/articles/news-2021/2021-research-excellence-awards-celebrate-three-of/
  • https://www.uwa.edu.au/news/Article/2021/October/UWA-scientists-recognised-in-Cancer-Council-WA-research-excellence-awards
  • https://wahtn.org/blog/2021/11/24/congratulations-to-raine-medical-research-foundation-funding-recipients/
  • https://www.youtube.com/watch?v=RI3hHpBgoWY
  • https://www.web.uwa.edu.au/university/publications/uniview/news-and-features/iqx-awards -interviewed
  • https://www.news.uwa.edu.au/archive/2018051510616/may-2018/2018-iq-awards-celebrate-new-inventions-make-world-better-place/- interviewed
  • http://www.news.uwa.edu.au/2018083010913/research/uwa-team-wins-eureka-prize
  • https://www.uwa.edu.au/health/-/media/Faculties/HMS/Docs/Highlights/2018-Highlights.pdf - headlined Faculty of Health & Medical Sciences biannual research highlights
  • https://campaign.uwa.edu.au/thankyou - “Thank you: Philanthropic Journeys” global community outreach campaign/publication - interviewed
  • https://www.youtube.com/watch?v=-AvLxCLkAJc
  • https://australian.museum/get-involved/eureka-prizes/2018-eureka-prize-winners/
  • https://thewest.com.au/news/health/eureka-for-uwa-scientists-in-cancer-holy-grail-ng-b88944680z
  • https://www.abc.net.au/news/science/2018-08-29/eureka-prizes-2018-five-awesome-innovations- australian-research/10179328
  • https://www.news.com.au/national/western-australia/eureka-for-uwa-scientists-in- cancer-holy-grail/news- story/668f83cda79451cef0d4b23a4ebf8d98
  • https://www.minister.industry.gov.au/ministers/karenandrews/media-releases/eureka-prize-winners-champions-science
  • https://particle.scitech.org.au/tech/new-wa-test-for-leukaemia-wins-eureka-prize/

Community engagement

My responsibility as an emerging leader in science has enabled me to promote medical research and technological innovation to a broad audience. This includes engagement of community groups through medical research advocacy, fundraisers, cancer patient education and charity events:

2025  “Punching for a Cure” PCH fund raising for childhood cancer – volunteer and participant

2021   8 on the Point gala dinner for leukaemia research fundraising

2020– Australian Society for Medical Research WA (ASMR) State Committee

2020– Telethon family festivals

2020   Dato Tk Low Joondalup Resort Charity Golf Day 

2018   University of Western Australia Health Campus Open Day

2013 – 2021  University of Western Australia Open Day – School of Biomedical Sciences

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water
  • SDG 15 - Life on Land
  • SDG 16 - Peace, Justice and Strong Institutions

Industry keywords

  • Diagnostics
  • Medical Devices
  • Biotechnology
  • Digital Health

Research expertise keywords

  • Flow cytometry
  • Imaging flow cytometry
  • Immunofluorescence & imaging
  • Fluorescence In Situ Hybridization
  • Cancer Biology
  • Protocol optimisation
  • Cutting-edge method development
  • Diagnostic tests
  • Medical technology
  • Innovation & Automation
  • Blood & genetic based diagnostics
  • Chronic Lymphocytic Leukaemia (CLL)
  • Multiple myeloma
  • Pediatric Leukaemia
  • Acute Lymphoblastic Leukaemia (ALL)
  • Intergrated platforms & systems
  • Automation

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