Personal profile
Biography
Professor Grant Morahan BSc(Hons), PhD, is a graduate of La Trobe and Melbourne Universities. He holds a doctorate in immunogenetics from the University of Melbourne. Grant is He worked as a Fogarty International Fellow at the prestigious Scripps Clinic and Research Foundation in California. Taking up a position at the Walter and Eliza Hall Institute of Medical Research in Melbourne, he led a research team working on the genetics of complex diseases and researching immunological tolerance.
His research has included genetics of type 1 diabetes in humans and in animal models; genetics of asthma, obesity, demyelinating diseases, cardiovascular disease and malaria; characterisation of mechanisms of immune tolerance; and production of monoclonal antibodies. To date, his work has resulted in the publication of over 100 scientific papers, including many in the world's leading scientific journals. Professor Morahan was the State Councillor of the Australasian Society for Immunology and founding President of the Immunology Group of Victoria; he is a member of the Steering Committee of the international Type I Diabetes Genetics Consortium; Principal Investigator of the Asia-Pacific Type I Diabetes Genetics Network; a member of the prestigious worldwide Faculty of 1000; and a founder of the Complex Trait Consortium. He was appointed in 2005 as the inaugural Diabetes Research Foundation Professor at the University of Western Australia, and the Director of the Centre for Diabetes Research at the Western Australian Institute for Medical Research at the Royal Perth Hospital campus. In addition to being Director of the Centre for Diabetes Research, Grant founded Geniad, a company which will offer pharmaceutical services based on a world-leading genetic resource, The Gene Mine. He is Chief Scientific Officer of Geniad.
Professor Grant Morahan established GordianTec Pty Ltd, which was founded in August 2011 to commercialise applications of technology developed by researchers at the Centre for Diabetes Research at the Harry Perkins Institute of Medical Research. GordianTec develops methods for improved patient management and better disease outcomes. GordianTec is responsible for filing patent applications for diagnostics in areas including diabetes and cancer. It is expanding application of its approach to new diseases.
Research expertise keywords
- Diabetes
- Gene mapping
- Pharmacogenetics
- Complex genetic diseases
- Systems genetics
- Bioinformatics
- Immunology
- Autoimmunity
- Gene discovery
- Animal models of disease
- Advanced genetics technologies
- Gene-diet interaction
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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A Genetic Test to Identify People at High Risk of Heart Failure
Ge, X., Brittain, B., Dawson, L., Dwivedi, G., Kaye, D. M. & Morahan, G., 19 Feb 2025, (E-pub ahead of print) In: International Journal of Molecular Sciences. 26, 4, 13 p., 1782.Research output: Contribution to journal › Article › peer-review
Open Access -
Indigenous infants in remote Australia retain an ancestral gut microbiome despite encroaching Westernization
ENDIA Study Group Consortium & Davis, E. A., 3 Dec 2025, In: Nature Communications. 16, 15 p., 9904.Research output: Contribution to journal › Article › peer-review
Open Access -
SARS-CoV-2 Infection and Childhood Islet Autoimmunity
ENDIA Study Group, Davis, E. A., Haynes, A. & Morahan, G., 5 May 2025, In: JAMA Pediatrics . 179, 5, p. 568-570 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
SEC61B regulates calcium flux and platelet hyperreactivity in diabetes
Kong, Y. X., Rehan, R., Moreno, C. L., Madsen, S., Zhang, Y., Zhao, H., Qi, M., Houlahan, C. B., Cartland, S. P., Robertshaw, D., Trang, V., Ong, F. J. L., Liu, M., Cheng, E., Alwis, I., Dupuy, A., Cielesh, M., Cooke, K. C., Potter, M. & Stöckli, J. & 15 others, , 2025, In: The Journal of clinical investigation. 135, 16, e184597.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Transcriptional regulation of Rankl by Txnip-Ecd in aging and diabetic related osteoporosis
Cao, X., Liu, K., Yuan, J., Hua, Q., Rong, K., Zhou, T., He, W., Pang, Y., Yang, X., Yu, Y., Zhang, P., Ma, P., Cao, Y., Zhao, J., Morahan, G., Xu, J. & Qin, A., Nov 2025, In: Journal of Advanced Research. 77, p. 221-234 14 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Citations (Scopus)
Datasets
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Age-dependent genetic regulation of osteoarthritis: independent effects of immune system genes
Kenny, J. (Contributor), Mullin, B. H. (Contributor), Tomlinson, W. (Contributor), Robertson, B. (Contributor), Yuan, J. (Contributor), Chen, W. (Contributor), Zhao, J. (Contributor), Pavlos, N. J. (Contributor), Walsh, J. P. (Contributor), Wilson, S. G. (Contributor), Tickner, J. (Contributor), Morahan, G. (Contributor) & Xu, J. (Contributor), Figshare, 16 Aug 2024
DOI: 10.6084/m9.figshare.c.6962026
Dataset
Projects
- 35 Finished
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NHMRC Equipment - Cytek laser and loader
Davern, K. (Investigator 01), Lister, R. (Investigator 02), Ganss, R. (Investigator 03), Leedman, P. (Investigator 04), Xu, J. (Investigator 05), Winteringham, L. (Investigator 07), Hamzah, J. (Investigator 08), Rackham, O. (Investigator 09) & Morahan, G. (Investigator 10)
NHMRC National Health and Medical Research Council
1/07/23 → 31/10/24
Project: Research
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ENDIA Helmsley Trust Funding
Morahan, G. (Investigator 01)
Leona M. and Harry B. Helmsley Charitable Trust
4/05/22 → 31/07/24
Project: Research
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NHMRC Equipment Grant qPCR
Pflueger, C. (Investigator 01), Lister, R. (Investigator 02), Laing, N. (Investigator 03), Ravenscroft, G. (Investigator 04), Morahan, G. (Investigator 05), Leedman, P. (Investigator 06), Blancafort, P. (Investigator 07), Forrest, A. (Investigator 08), Nilsson, J. (Investigator 09), Waryah, C. (Investigator 10), Chee, J. (Investigator 11) & Gaudieri, S. (Investigator 13)
NHMRC National Health and Medical Research Council
14/02/22 → 10/02/23
Project: Research
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How genetic background influences the development of mesothelioma (in asbestos exposed populations)
Fisher, S. (Investigator 01), Morahan, G. (Investigator 02) & Lake, R. (Investigator 03)
NHMRC National Health and Medical Research Council
1/01/19 → 31/12/23
Project: Research
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The MexTAg Collaborative Cross: understanding genetic modifiers in mesothelioma
Lake, R. (Investigator 01), Fisher, S. (Investigator 02), Morahan, G. (Investigator 03), Ram, R. (Investigator 04), Lesterhuis, W. (Investigator 05) & Nowak, A. (Investigator 06)
Department of War (United States)
1/05/18 → 31/01/22
Project: Research