Gerald Watts

Winthrop Professor, DSc MB BS Lond., PhD W.Aust., DM S'ton, FRCP, FRACP

  • The University of Western Australia (M570), 35 Stirling Highway,

    6009 Perth

    Australia

  • 22114 Citations
  • 72 h-Index
1994 …2020
If you made any changes in Pure these will be visible here soon.

Research Output 1994 2019

Filter
Review article
2019

A new approach to the diagnosis and treatment of atherosclerosis: the era of the liposome

Kiaie, N., Gorabi, A. M., Penson, P. E., Watts, G., Johnston, T. P., Banach, M. & Sahebkar, A., 13 Sep 2019, (Accepted/In press) In : Drug Discovery Today. 15 p.

Research output: Contribution to journalReview article

Liposomes
Atherosclerosis
Cardiovascular Diseases
Therapeutics
Angina Pectoris

Effect of Statin Therapy on Arterial Wall Inflammation Based on 18F-FDG PET/CT: A Systematic Review and Meta-Analysis of Interventional Studies

Pirro, M., Simental-Mendia, L. E., Bianconi, V., Watts, G. F., Banach, M. & Sahebkar, A., Jan 2019, In : Journal of Clinical Medicine. 8, 1, 14 p., 118.

Research output: Contribution to journalReview article

Open Access
Precision Medicine
Hyperlipoproteinemia Type II
Coronary Disease
Genetic Testing
Dyslipidemias
2 Citations (Scopus)

Improving the detection of familial hypercholesterolaemia

Lan, N. S. R., Martin, A. C., Brett, T., Watts, G. F. & Bell, D. A., Feb 2019, In : Pathology. 51, 2, p. 213-221 9 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Lipoprotein(a) as a risk factor for calcific aortic valvulopathy in heterozygous familial hypercholesterolemia

Vuorio, A., Watts, G. F. & Kovanen, P. T., Feb 2019, In : Atherosclerosis. 281, p. 25-30 6 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

PCSK9 inhibition 2018: riding a new wave of coronary prevention

Ward, N. C., Page, M. M. & Watts, G. F., 31 Jan 2019, In : Clinical Science. 133, 2, p. 205-224 20 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Recent advances in synthetic pharmacotherapies for dyslipidaemias

Sirtori, C. R., Yamashita, S., Francesca Greco, M., Corsini, A., F Watts, G. & Ruscica, M., 6 May 2019, In : European Journal of Preventive Cardiology.

Research output: Contribution to journalReview article

Dyslipidemias
LDL Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypertriglyceridemia
Drug Therapy

Residual vascular risk in diabetes – Will the SPPARM alpha concept hold the key?

International Atherosclerosis Society/R3i Foundation Consensus Panel, 1 Jul 2019, In : Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 13, 4, p. 2723-2725 3 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Safety of red yeast rice supplementation: A systematic review and meta-analysis of randomized controlled trials

Lipid Blood Pressure Meta-Anal & ILEP, May 2019, In : Pharmacological Research. 143, p. 1-16 16 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Status of PCSK9 Monoclonal Antibodies in Australia

Scherer, D. J., Nelson, A. J., O'Brien, R., Kostner, K. M., Hare, D. L., Colquhoun, D. M., Barter, P. J., Aylward, P., Nicholls, S. J. & Watts, G. F., 1 Oct 2019, In : Heart Lung and Circulation. 28, 10, p. 1571-1579 9 p.

Research output: Contribution to journalReview article

Monoclonal Antibodies
Hyperlipoproteinemia Type II
Hypercholesterolemia
LDL Cholesterol
Prescriptions
3 Citations (Scopus)

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARM) paradigm: conceptual framework and therapeutic potential: A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

Fruchart, J-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Despres, J-P., Duriez, P., Eckel, R. H., Ezhov, M. V., Farnier, M., Ginsberg, H. N., Hermans, M. P., Ishibashi, S., Karpe, F., Kodama, T., Koenig, W. & 35 othersKrempf, M., Lim, S., Lorenzatti, A. J., McPherson, R., Millan Nunez-Cortes, J., Nordestgaard, B. G., Ogawa, H., Packard, C. J., Plutzky, J., Ponte-Negretti, C. I., Pradhan, A., Ray, K. K., Reiner, Z., Ridker, P. M., Ruscica, M., Sadikot, S., Shimano, H., Sritara, P., Stock, J. K., Su, T-C., Susekov, A. V., Tartar, A., Taskinen, M-R., Tenenbaum, A., Tokgozoglu, L. S., Tomlinson, B., Tybjaerg-Hansen, A., Valensi, P., Vrablik, M., Wahli, W., Watts, G. F., Yamashita, S., Yokote, K., Zambon, A. & Libby, P., 4 Jun 2019, In : Cardiovascular Diabetology. 18, 1, 20 p., 71.

Research output: Contribution to journalReview article

Open Access

To test, or not to test: that is the question for the future of lipoprotein(a)

Ellis, K. L., Chakraborty, A., Moses, E. K. & Watts, G. F., 3 Apr 2019, In : Expert Review of Cardiovascular Therapy. 17, 4, p. 241-250 10 p.

Research output: Contribution to journalReview article

Lipoprotein(a)
Cardiovascular Diseases
Guidelines
Genetically Modified Animals
Expert Testimony
2018
14 Citations (Scopus)

Effects of Allopurinol on Endothelial Function: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials

Cicero, A. F. G., Pirro, M., Watts, G. F., Mikhailidis, D. P., Banach, M. & Sahebkar, A., 1 Jan 2018, In : Drugs. 78, 1, p. 99-109 11 p.

Research output: Contribution to journalReview article

Allopurinol
Meta-Analysis
Dilatation
Randomized Controlled Trials
Placebos
3 Citations (Scopus)
Sodium Fluoride
Positron-Emission Tomography
Cardiovascular Diseases
Vascular Calcification
Calcium
2 Citations (Scopus)

Is Lipoprotein(a) Ready for Prime-Time Use in the Clinic?

Ellis, K. L. & Watts, G. F., 1 May 2018, In : Cardiology Clinics. 36, 2, p. 287-298 12 p.

Research output: Contribution to journalReview article

Lipoprotein(a)
Cardiovascular Diseases
Apoprotein(a)
Aortic Valve Stenosis
LDL Lipoproteins
10 Citations (Scopus)

Lipoprotein(a) and secondary prevention of atherothrombotic events: A critical appraisal

Boffa, M. B., Stranges, S., Klar, N., Moriarty, P. M., Watts, G. F. & Koschinsky, M. L., 1 Nov 2018, In : Journal of Clinical Lipidology. 12, 6, p. 1358-1366 9 p.

Research output: Contribution to journalReview article

Lipoprotein(a)
Secondary Prevention
Preexisting Condition Coverage
Population
Coronary Disease
16 Citations (Scopus)

MicroRNAs: Novel Molecular Targets and Response Modulators of Statin Therapy

Mohajeri, M., Banach, M., Atkin, S. L., Butler, A. E., Ruscica, M., Watts, G. F. & Sahebkar, A., 1 Nov 2018, In : Trends in Pharmacological Sciences. 39, 11, p. 967-981 15 p.

Research output: Contribution to journalReview article

Hydroxymethylglutaryl-CoA Reductase Inhibitors
MicroRNAs
Modulators
Cardiovascular Diseases
Cholesterol
7 Citations (Scopus)
Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Dietary Supplements
LDL Cholesterol
Muscles
Cardiovascular Diseases
13 Citations (Scopus)
Cardiovascular Diseases
Monoclonal Antibodies
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Therapeutics
Hyperlipoproteinemias
4 Citations (Scopus)

Screening for familial hypercholesterolaemia in primary care: Time for general practice to play its part

Brett, T., Qureshi, N., Gidding, S. & Watts, G. F., 1 Oct 2018, In : Atherosclerosis. 277, p. 399-406 8 p.

Research output: Contribution to journalReview article

Hyperlipoproteinemia Type II
General Practice
Primary Health Care
Electronic Health Records
Information Storage and Retrieval
2 Citations (Scopus)
Hyperlipoproteinemia Type II
Genetic Testing
High-Throughput Nucleotide Sequencing
Genomics
Hypercholesterolemia
43 Citations (Scopus)

The Role of Nutraceuticals in Statin Intolerant Patients

International Lipid Expert Panel (ILEP), 3 Jul 2018, In : Journal of the American College of Cardiology. 72, 1, p. 96-118 23 p.

Research output: Contribution to journalReview article

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Dietary Supplements
Cardiovascular Diseases
Cynara scolymus
Berberine
2017
13 Citations (Scopus)
Hyperlipoproteinemia Type II
Immunization
Electronic Health Records
Inborn Genetic Diseases
Computational Biology
12 Citations (Scopus)
Hyperlipoproteinemia Type II
Acute Coronary Syndrome
Monoclonal Antibodies
Clinical Trials
LDL Cholesterol
62 Citations (Scopus)

Optimizing cholesterol treatment in patients with muscle complaints

Rosenson, R. S., Baker, S., Banach, M., Borow, K. M., Braun, L. T., Bruckert, E., Brunham, L. R., Catapano, A. L., Elam, M. B., Mancini, G. B. J., Moriarty, P. M., Morris, P. B., Muntner, P., Ray, K. K., Stroes, E. S., Taylor, B. A., Taylor, V. H., Watts, G. F. & Thompson, P. D., 5 Sep 2017, In : Journal of the American College of Cardiology. 70, 10, p. 1290-1301 12 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Preferred Fourth-Line Pharmacotherapy for Resistant Hypertension: Are We There Yet?

Prosser, H. C., Gregory, C., Hering, D., Hillis, G. S., Perry, G., Rosman, J., Schultz, C., Thomas, M., Watts, G. F. & Schlaich, M. P., 1 Apr 2017, In : Current Hypertension Reports. 19, 4, 30.

Research output: Contribution to journalReview article

Hypertension
Drug Therapy
Adrenergic Antagonists
Antihypertensive Agents
Pharmaceutical Preparations
19 Citations (Scopus)

Recent perspectives on the role of nutraceuticals as cholesterol-lowering agents

Ward, N., Sahebkar, A., Banach, M. & Watts, G., 1 Dec 2017, In : Current Opinion in Lipidology. 28, 6, p. 495-501 7 p.

Research output: Contribution to journalReview article

Dietary Supplements
Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Berberine
Phytosterols
6 Citations (Scopus)
26 Citations (Scopus)

The renaissance of lipoprotein(a): Brave new world for preventive cardiology?

Ellis, K. L., Boffa, M. B., Sahebkar, A., Koschinsky, M. L. & Watts, G. F., 1 Oct 2017, In : Progress in Lipid Research. 68, p. 57-82 26 p.

Research output: Contribution to journalReview article

Cardiology
Lipoprotein(a)
Plasmas
Renaissance
Epidemiology
33 Citations (Scopus)

Toward an international consensus-Integrating lipoprotein apheresis and new lipid-lowering drugs

Stefanutti, C., Julius, U., Watts, G. F., Harada-Shiba, M., Cossu, M., Schettler, V. J., De Silvestro, G., Soran, H., Van Lennep, J. R., Pisciotta, L., Kloer, H. U., Widhalm, K., Moriarty, P. M. & MIGHTY MEDIC Multinational Society, Aug 2017, In : Journal of Clinical Lipidology. 11, 4, p. 858-871 14 p.

Research output: Contribution to journalReview article

Open Access
2016
7 Citations (Scopus)

Challenges in the health economics of familial hypercholesterolemia

Norman, R., Watts, G. F., Weintraub, W. & Gidding, S. S., 13 Nov 2016, In : Current Opinion in Lipidology. 27, 6, p. 563-569 7 p.

Research output: Contribution to journalReview article

Hyperlipoproteinemia Type II
Cost-Benefit Analysis
Economics
Health
Hydroxymethylglutaryl-CoA Reductase Inhibitors
125 Citations (Scopus)

Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society Severe Familial Hypercholesterolemia Panel

Santos, R. D., Gidding, S. S., Hegele, R. A., Cuchel, M. A., Barter, P. J., Watts, G. F., Baum, S. J., Catapano, A. L., Chapman, M. J., Defesche, J. C., Folco, E., Freiberger, T., Genest, J., Hovingh, G. K., Harada-Shiba, M., Humphries, S. E., Jackson, A. S., Mata, P., Moriarty, P. M., Raal, F. J. & 5 othersAl-Rasadi, K., Ray, K. K., Reiner, Z., Sijbrands, E. J. G. & Yamashita, S., 2016, In : The Lancet Diabetes and Endocrinology. 4, 10, p. 850-861 12 p.

Research output: Contribution to journalReview article

Open Access
Hyperlipoproteinemia Type II
Phenotype
Hypercholesterolemia
LDL Cholesterol
Coronary Artery Disease
24 Citations (Scopus)

International developments in the care of familial hypercholesterolemia: Where now and where to next?

Pang, J., Lansberg, P. J. & Watts, G. F., 2016, In : Journal of Atherosclerosis and Thrombosis. 23, 5, p. 505-519 15 p.

Research output: Contribution to journalReview article

Drug therapy
Hyperlipoproteinemia Type II
Lipoproteins
Screening
Testing
4 Citations (Scopus)

Management of familial hypercholesterolemia in Hong Kong

Hu, M., Hooper, A. J., van Bockxmeer, F. M., Watts, G. F., Chan, J. C. N. & Tomlinson, B., 2016, In : Journal of Atherosclerosis and Thrombosis. 23, 5, p. 520-531 12 p.

Research output: Contribution to journalReview article

Hyperlipoproteinemia Type II
Hong Kong
LDL Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coronary Disease
19 Citations (Scopus)
Apolipoproteins B
Cardiovascular Diseases
Familial Combined Hyperlipidemia
Hyperlipoproteinemia Type II
Lipoprotein(a)
10 Citations (Scopus)

Progress in the care of familial hypercholesterolaemia: 2016

Bell, D. A. & Watts, G. F., 5 Sep 2016, In : Medical Journal of Australia. 205, 5, p. 232-236 5 p.

Research output: Contribution to journalReview article

Open Access
Hyperlipoproteinemia Type II
LDL Cholesterol
Cardiovascular Diseases
Lipoprotein(a)
Primary Prevention
19 Citations (Scopus)
Hyperlipoproteinemia Type II
LDL Cholesterol
Lipoproteins
Genetic Testing
Therapeutics
1 Citation (Scopus)
121 Downloads (Pure)
Open Access
File
Apolipoproteins B
Lipoproteins
Drug Therapy
Niacin
Apolipoprotein A-I
15 Citations (Scopus)

Statin therapy and plasma free fatty acids: A systematic review and meta-analysis of controlled clinical trials

Sahebkar, A., Simental-Mendía, L. E., Pedone, C., Ferretti, G., Nachtigal, P., Bo, S., Derosa, G., Maffioli, P. & Watts, G. F., 2016, In : British Journal of Clinical Pharmacology. 81, 5, p. 807-818 12 p.

Research output: Contribution to journalReview article

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Controlled Clinical Trials
Nonesterified Fatty Acids
Meta-Analysis
Therapeutics
52 Citations (Scopus)

The impact of statin therapy on plasma levels of von Willebrand factor antigen: Systematic review and meta-analysis of Randomised placebo-controlled trials

Sahebkar, A., Serban, C., Ursoniu, S., Mikhailidis, D. P., Undas, A., Lip, G. Y. H., Bittner, V., Ray, K. K., Watts, G. F., Kees Hovingh, G., Rysz, J., Kastelein, J. J. P. & Banach, M., 2016, In : Thrombosis and Haemostasis. 115, 3, p. 520-532 13 p.

Research output: Contribution to journalReview article

Hydroxymethylglutaryl-CoA Reductase Inhibitors
von Willebrand Factor
Meta-Analysis
Randomized Controlled Trials
Placebos
22 Citations (Scopus)

Translational research for improving the care of familial hypercholesterolemia: The “ten countries study” and beyond

Watts, G. F., Ding, P. Y., George, P., Hagger, M. S., Hu, M., Lin, J., Khoo, K. L., Marais, A. D., Miida, T., Nawawi, H. M., Pang, J., Park, J. E., Gonzalez-Santos, L. B., Su, T. C., Truong, T. H., Santos, R. D., Soran, H., Yamashita, S., Tomlinson, B., Arikketh, D. & 31 othersAshavaid, T. F., Atiqah, N., Balasubramaniam, S., Chan, D. C., Chang, N. T., Do, T. C., Zhao, D., Ellis, K. L., Han, K. H., Hardcastle, S. J., Jannes, C. E., Kassim, A. M., Ismail, Z. M., Kwok, S., Lam, C. S., Lansberg, P. J., Livingston, M., Mehta, M., Muir, L., Peng, H. B., Pereira, A. C., Rahman, T. H. A., Ramli, A. S., Rangarajan, N., Razak, S. A., Sijbrands, E. J., Sullivan, D. R., Shyong Tai, E., Tan, H. C., Verma, I. C. & Wu, X., 2016, In : Journal of Atherosclerosis and Thrombosis. 23, 8, p. 891-900 10 p.

Research output: Contribution to journalReview article

Hyperlipoproteinemia Type II
Translational Medical Research
LDL Receptors
Availability
Atherosclerosis
2015
14 Citations (Scopus)

Cardiac computed tomography imaging in familial hypercholesterolaemia: implications for therapy and clinical trials

Sijbrands, E. J. G., Nieman, K., Budoff, M. J., FH CTA Consortium, Watts, G. & Bell, D., Dec 2015, In : Current Opinion in Lipidology. 26, 6, p. 586-592 7 p.

Research output: Contribution to journalReview article

Hyperlipoproteinemia Type II
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coronary Artery Disease
Angiography
Tomography
4 Citations (Scopus)
Hypertriglyceridemia
Glass
Triglycerides
Pancreatitis
Fasting
44 Citations (Scopus)

Effect of dietary Fatty acids on human lipoprotein metabolism: A comprehensive update

Ooi, E. M. M., Watts, G. F., Ng, T. W. K. & Barrett, P. H. R., 2 Jun 2015, In : Nutrients. 7, 6, p. 4416-4425 10 p.

Research output: Contribution to journalReview article

Open Access
dietary fat
lipoproteins
Lipoproteins
Fatty Acids
metabolism
262 Citations (Scopus)

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

European Atherosclerosis Society Consensus Panel, 21 Sep 2015, In : European Heart Journal. 36, 36, p. 2425-2437 13 p.

Research output: Contribution to journalReview article

Open Access
Hyperlipoproteinemia Type II
LDL Cholesterol
Coronary Disease
Therapeutics
Hydroxymethylglutaryl-CoA Reductase Inhibitors
5 Citations (Scopus)

The hinterland of familial hypercholesterolaemia: what do we not know?

Wierzbicki, A. S. & Watts, G. F., Dec 2015, In : Current Opinion in Lipidology. 26, 6, p. 475-483 9 p.

Research output: Contribution to journalReview article

Hyperlipoproteinemia Type II
Guidelines
Epidemiology
Cardiovascular Diseases
Life Style
2014
28 Citations (Scopus)

An International Atherosclerosis Society Position Paper: Global recommendations for the management of dyslipidemia. Executive summary.

Grundy., S. M., Arai, H., Barter, P. J., Bersot, T. P., Betteridge, D. J. B., Carmena, R., Cuevas, A. M., Davidson, M. H., Genest, J. J. G., Kesäniemi, Y. A., Sadikot, S. M., Santos, R. D., Susekov, A. V., Sy, R., Tokgözoĝlu, L. S., Watts, G. & Zhao, D., 2014, In : Atherosclerosis. 232, 2, p. 410-413

Research output: Contribution to journalReview article

6 Citations (Scopus)

Critical review of non-statin treatments for dyslipoproteinemia

Pang, J., Chan, D. & Watts, G., 2014, In : Expert Review of Cardiovascular Therapy. 12, 3, p. 359-371

Research output: Contribution to journalReview article

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Dyslipidemias
Hyperlipoproteinemia Type I
Fibric Acids
Hyperlipoproteinemia Type II
419 Citations (Scopus)

Homozygous familial hypercholesterolaemia: New insights and guidance for clinicians to improve detection and clinical management. A position paper fromthe Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

Cuchel, M., Bruckert, E., Ginsberg, H. N., Raal, F. J., Santos, R. D., Hegele, R. A., Kuivenhoven, J. A., Nørdestgaard, B. G., Descamps, O. S., Steinhagen-Thiessen, E., Tybjærg-Hansen, A., Watts, G., Averna, M. R., Boileau, C. R., Borén, J. B., Catapano, A., Defesche, J. C., Hovingh, G. K., Humphries, S. E., Kovanen, P. T. & 10 othersMasana, L. L., Pajukanta, P. E., Parhofer, K. G., Ray, K. K., Stalenhoef, A. F. H., Stroes, E. S. G., Taskinen, M. R., Wiegman, A., Wiklund, O. & Chapman, M. J., 2014, In : European Heart Journal. 35, 32, p. 2146-2157

Research output: Contribution to journalReview article

Open Access
Hyperlipoproteinemia Type II
Consensus
LDL Cholesterol
Therapeutics
Cardiovascular Diseases
191 Citations (Scopus)
130 Downloads (Pure)

Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation

Watts, G., Gidding, S. S., Wierzbicki, A. S., Tóth, P. P., Alonso, R. M., Brown, W. V., Bruckert, E., Defesche, J. C., Lin, K., Livingston, M. C. P., Mata, P., Parhofer, K. G., Raal, F. J., Santos, R. D., Sijbrands, E. J., Simpson, W. G., Sullivan, D. R., Susekov, A. V., Tomlinson, B. T., Wiegman, A. & 2 othersYamashita, S. & Kastelein, J. J. P., 2014, In : International Journal of Cardiology. 171, 3, p. 309-325

Research output: Contribution to journalReview article

Open Access
File
Hyperlipoproteinemia Type II
Blood Component Removal
Internationality
Health Resources
Risk Management