Gerald Watts

Winthrop Professor, DSc MB BS Lond., PhD W.Aust., DM S'ton, FRCP, FRACP

  • The University of Western Australia (M570), 35 Stirling Highway,

    6009 Perth

    Australia

  • 21308 Citations
  • 71 h-Index
1994 …2020
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Research Output 1994 2019

2019

A cross-national investigation of cardiovascular survival in homozygous familial hypercholesterolaemia: the Sino-Roman Study

Stefanutti, C., Pang, J., Di Giacomo, S., Wu, X., Wang, X., Morozzi, C., Watts, G. F. & Lin, J., 12 May 2019, In : Journal of Clinical Lipidology.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Blood Component Removal
LDL Cholesterol
Survival
Lipoproteins

A window into the heart of familial hypercholesterolaemia in the community

Watts, G. F. & Pang, J., 1 May 2019, In : The Lancet Public Health. 4, 5, p. e216-e217

Research output: Contribution to journalEditorial

Open Access
LDL Cholesterol
Monoclonal Antibodies
Cardiovascular Diseases
Guidelines
Hydroxymethylglutaryl-CoA Reductase Inhibitors
1 Citation (Scopus)

Comparative aspects of the care of familial hypercholesterolemia in the “Ten Countries Study”

Pang, J., Chan, D. C., Hu, M., Muir, L. A., Kwok, S., Charng, M. J., Florkowski, C. M., George, P. M., Lin, J., Loi, D. D., Marais, A. D., Nawawi, H. M., Gonzalez-Santos, L. E., Su, T. C., Truong, T. H., Santos, R. D., Soran, H., Tomlinson, B., Yamashita, S., Ademi, Z. & 1 othersWatts, G. F., Apr 2019, In : Journal of Clinical Lipidology. 13, 2, p. 287-300

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Delivery of Health Care
Genetic Testing
Education
Developing Countries
1 Citation (Scopus)

Dyslipidaemia in adults with type 1 diabetes-when to treat?

Lan, N. S. R., Fegan, P. G., Yeap, B. B., Bell, D. A. & Watts, G. F., Jan 2019, In : Diabetes/Metabolism Research and Reviews. 35, 1, 5 p., 3090.

Research output: Contribution to journalEditorial

Effect of Statin Therapy on Arterial Wall Inflammation Based on 18F-FDG PET/CT: A Systematic Review and Meta-Analysis of Interventional Studies

Pirro, M., Simental-Mendia, L. E., Bianconi, V., Watts, G. F., Banach, M. & Sahebkar, A., Jan 2019, In : Journal of Clinical Medicine. 8, 1, 14 p., 118.

Research output: Contribution to journalReview article

Open Access
Apolipoprotein B-100
Apoprotein(a)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoprotein(a)
Apolipoproteins B

Icosapent ethyl for dyslipidaemia in patients with diabetes and coronary artery disease: Act now to reduce it

Lan, N. S. R., Fegan, P. G., Yeap, B. B., Rankin, J. M. & Watts, G. F., 1 Jul 2019, In : Diabetes, Obesity and Metabolism. 21, 7, p. 1734-1736 3 p.

Research output: Contribution to journalArticle

Dyslipidemias
Coronary Artery Disease
Acute Coronary Syndrome
Cardiovascular Diseases
Hydroxymethylglutaryl-CoA Reductase Inhibitors
1 Citation (Scopus)

Impact of PCSK9 inhibitors on plasma lipoprotein(a) concentrations with or without a background of niacin therapy

Warden, B. A., Minnier, J., Watts, G. F., Fazio, S. & Shapiro, M. D., 26 Apr 2019, In : Journal of Clinical Lipidology.

Research output: Contribution to journalArticle

Lipoprotein(a)
Niacin
Group Psychotherapy
Therapeutics
Proprotein Convertase 9
1 Citation (Scopus)

Improving the detection of familial hypercholesterolaemia

Lan, N. S. R., Martin, A. C., Brett, T., Watts, G. F. & Bell, D. A., Feb 2019, In : Pathology. 51, 2, p. 213-221 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
Blood Component Removal
Lipoprotein(a)
Apolipoproteins B
LDL Lipoproteins
Metabolism
2 Citations (Scopus)

Lipoprotein(a) as a risk factor for calcific aortic valvulopathy in heterozygous familial hypercholesterolemia

Vuorio, A., Watts, G. F. & Kovanen, P. T., Feb 2019, In : Atherosclerosis. 281, p. 25-30 6 p.

Research output: Contribution to journalReview article

Open Access
Apoprotein(a)
Lipoprotein(a)
Protein Isoforms
Cholesterol
Therapeutics
3 Citations (Scopus)

Loneliness in psychotic illness and its association with cardiometabolic disorders

Badcock, J. C., Mackinnon, A., Waterreus, A., Watts, G. F., Castle, D., McGrath, J. J. & Morgan, V. A., Feb 2019, In : Schizophrenia Research. 204, p. 90-95 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

PCSK9 inhibition 2018: riding a new wave of coronary prevention

Ward, N. C., Page, M. M. & Watts, G. F., 31 Jan 2019, In : Clinical Science. 133, 2, p. 205-224 20 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

PCSK9 in HIV infection: New opportunity or red herring?

Ruscica, M., Watts, G. F. & Sirtori, C. R., 1 May 2019, In : Atherosclerosis. 284, p. 216-217 2 p.

Research output: Contribution to journalEditorial

PCSK9 monoclonal antibodies and lipoprotein apheresis for lowering lipoprotein(a): making choices in an era of RNA-based therapies

Ruscica, M., Watts, G. F. & Sirtori, C. R., Jun 2019, In : European Journal of Preventive Cardiology. 26, 9, p. 998-1000 3 p.

Research output: Contribution to journalEditorial

Potential utility of the SAFEHEART risk equation for rationalising the use of PCSK9 monoclonal antibodies in adults with heterozygous familial hypercholesterolemia

Pérez de Isla, L., Ray, K. K., Watts, G. F., Santos, R. D., Alonso, R., Muñiz-Grijalvo, O., Diaz-Diaz, J. L., Badimon, L., Catapano, A. L. & Mata, P., 1 Jul 2019, In : Atherosclerosis. 286, p. 40-45 6 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Monoclonal Antibodies
LDL Cholesterol
Numbers Needed To Treat
Therapeutics
4 Citations (Scopus)

Safety of red yeast rice supplementation: A systematic review and meta-analysis of randomized controlled trials

Lipid Blood Pressure Meta-Anal & ILEP, May 2019, In : Pharmacological Research. 143, p. 1-16 16 p.

Research output: Contribution to journalReview article

Simon Broome confirms that the IAS definition of severe familial hypercholesterolemia predicts coronary mortality in patients with FH

Santos, R. D. & Watts, G. F., Feb 2019, In : Atherosclerosis. 281, p. 145-147 3 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Statin Toxicity

Ward, N. C., Watts, G. F. & Eckel, R. H., 18 Jan 2019, In : Circulation Research. 124, 2, p. 328-350 23 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Muscles
Primary Prevention
Secondary Prevention
LDL Cholesterol
Interleukin-18
Omega-3 Fatty Acids
Interleukin-12
Chronic Renal Insufficiency
C-Reactive Protein

The relationship between pulse pressure and inflammation with left ventricular diastolic dysfunction in chronic kidney disease patients

Yong, K., Mori, T., Chew, G., Beilin, L. J., Puddey, I., Watts, G., Dogra, G., Boudville, N. & Lim, W., 12 Feb 2019, In : Internal Medicine Journal. 49, 2, p. 240-247

Research output: Contribution to journalArticle

Left Ventricular Dysfunction
Chronic Renal Insufficiency
Interleukin-18
Interleukin-12
Blood Pressure

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARM) paradigm: conceptual framework and therapeutic potential: A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

Fruchart, J-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Despres, J-P., Duriez, P., Eckel, R. H., Ezhov, M. V., Farnier, M., Ginsberg, H. N., Hermans, M. P., Ishibashi, S., Karpe, F., Kodama, T., Koenig, W. & 35 othersKrempf, M., Lim, S., Lorenzatti, A. J., McPherson, R., Millan Nunez-Cortes, J., Nordestgaard, B. G., Ogawa, H., Packard, C. J., Plutzky, J., Ponte-Negretti, C. I., Pradhan, A., Ray, K. K., Reiner, Z., Ridker, P. M., Ruscica, M., Sadikot, S., Shimano, H., Sritara, P., Stock, J. K., Su, T-C., Susekov, A. V., Tartar, A., Taskinen, M-R., Tenenbaum, A., Tokgozoglu, L. S., Tomlinson, B., Tybjaerg-Hansen, A., Valensi, P., Vrablik, M., Wahli, W., Watts, G. F., Yamashita, S., Yokote, K., Zambon, A. & Libby, P., 4 Jun 2019, In : Cardiovascular Diabetology. 18, 1, 20 p., 71.

Research output: Contribution to journalReview article

Open Access

To test, or not to test: that is the question for the future of lipoprotein(a)

Ellis, K. L., Chakraborty, A., Moses, E. K. & Watts, G. F., 3 Apr 2019, In : Expert Review of Cardiovascular Therapy. 17, 4, p. 241-250 10 p.

Research output: Contribution to journalReview article

Lipoprotein(a)
Cardiovascular Diseases
Guidelines
Genetically Modified Animals
Expert Testimony
2 Citations (Scopus)

Value of Measuring Lipoprotein(a) During Cascade Testing for Familial Hypercholesterolemia

Ellis, K. L., Pérez de Isla, L., Alonso, R., Fuentes, F., Watts, G. F. & Mata, P., 12 Mar 2019, In : Journal of the American College of Cardiology. 73, 9, p. 1029-1039 11 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Lipoprotein(a)
Cardiovascular Diseases

What's new on therapies for elevated lipoprotein(a)

Ward, N. C., Schultz, C. J. & Watts, G. F., 3 Jun 2019, In : Expert Review of Clinical Pharmacology. 12, 6, p. 495-499 5 p.

Research output: Contribution to journalEditorial

Lipoprotein(a)
Software
Molecular Sequence Annotation
Protein Databases
Peptides
2018
8 Citations (Scopus)
42 Downloads (Pure)
Open Access
File
Hyperlipoproteinemia Type II
Lipids
Mutation
Early Diagnosis
Xanthomatosis
Blood Platelets
Exercise
Platelet Activation
Brachial Artery
Acute Coronary Syndrome
5 Citations (Scopus)

Association between phenotypic familial hypercholesterolaemia and telomere length in US adults: results from a multi-ethnic survey

Banach, M., Mazidi, M., Mikhailidis, D. P., Toth, P. P., Jozwiak, J., Rysz, J. & Watts, G. F., 21 Oct 2018, In : European Heart Journal. 39, 40, p. 3635-3640 6 p.

Research output: Contribution to journalArticle

Open Access
Hyperlipoproteinemia Type II
Telomere
Confidence Intervals
Nutrition Surveys
Lipids
3 Citations (Scopus)
Open Access
Apolipoprotein B-48
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoproteins
Triglycerides
Apolipoprotein B-100

Controlled study of the effect of proprotein convertase subtilisin-kexin type 9 inhibition with evolocumab on lipoprotein(a) particle kinetics

Watts, G. F., Chan, D. C., Somaratne, R., Wasserman, S. M., Scott, R., Marcovina, S. M. & Barrett, P. H. R., 14 Jul 2018, In : European Heart Journal. 39, 27, p. 2577-2585 9 p.

Research output: Contribution to journalArticle

Lipoprotein(a)
Apoprotein(a)
AMG 145
Proprotein Convertase 9
Apolipoproteins B

Dyslipidemia

Chan, D. T., Irish, A. B. & Watts, G. F., 1 Jan 2018, Handbook of Chronic Kidney Disease Management. 2nd ed. Kluwer Academic Publishers, p. 192-216 25 p.

Research output: Chapter in Book/Conference paperChapter

Editorial introductions (in Current Opinion in Lipidology)

Stroes, E. S. G. & Watts, G. F., Dec 2018, In : Current Opinion in Lipidology. 29, 6, p. 433-433 1 p.

Research output: Contribution to journalEditorial

11 Citations (Scopus)

Effects of Allopurinol on Endothelial Function: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials

Cicero, A. F. G., Pirro, M., Watts, G. F., Mikhailidis, D. P., Banach, M. & Sahebkar, A., 1 Jan 2018, In : Drugs. 78, 1, p. 99-109 11 p.

Research output: Contribution to journalReview article

Allopurinol
Meta-Analysis
Dilatation
Randomized Controlled Trials
Placebos
2 Citations (Scopus)

Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia

Hagger, M. S., Hardcastle, S. J., Hu, M., Kwok, S., Lin, J., Nawawi, H. M., Pang, J., Santos, R. D., Soran, H., Su, T-C., Tomlinson, B. & Watts, G. F., Oct 2018, In : Atherosclerosis. 277, p. 493-501 9 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Therapeutics
Cross-Sectional Studies
Cholesterol
Demography
7 Citations (Scopus)
Coronary Care Units
Hyperlipoproteinemia Type II
Lipoprotein(a)
Coronary Artery Disease
Acute Coronary Syndrome
3 Citations (Scopus)
Lipoprotein(a)
LDL Cholesterol
Coronary Artery Disease
Coronary Care Units
Hyperlipoproteinemia Type II
1 Citation (Scopus)

Fenofibrate effects on carotid artery intima-media thickness in adults with type 2 diabetes mellitus: A FIELD substudy

Harmer, J. A., Keech, A. C., Veillard, A. S., Skilton, M. R., Watts, G. F. & Celermajer, D. S., 1 Jul 2018, In : Diabetes Research and Clinical Practice. 141, p. 156-167 12 p.

Research output: Contribution to journalArticle

Fenofibrate
Carotid Intima-Media Thickness
Carotid Arteries
Type 2 Diabetes Mellitus
Dyslipidemias
9 Citations (Scopus)
62 Downloads (Pure)

Health literacy in familial hypercholesterolemia: A cross-national study

Hagger, M. S., Hardcastle, S. J., Hu, M., Kwok, S., Lin, J., Nawawi, H. M., Pang, J., Santos, R. D., Soran, H., Su, T-C., Tomlinson, B. & Watts, G. F., Jun 2018, In : European Journal of Cardiovascular Prevention & Rehabilitation. 25, 9, p. 936-943

Research output: Contribution to journalArticle

Open Access
File
Health Literacy
Hyperlipoproteinemia Type II
China
Malaysia
Hong Kong
2 Citations (Scopus)

Heterozygous familial hypercholesterolaemia in specialist centres in South Africa, Australia and Brazil: Importance of early detection and lifestyle advice

Pang, J., David Marais, A., Blom, D. J., Brice, B. C., Silva, P. R., Jannes, C. E., Pereira, A. C., Hooper, A. J., Ray, K. K., Santos, R. D. & Watts, G. F., Oct 2018, In : Atherosclerosis. 277, p. 470-476 7 p.

Research output: Contribution to journalArticle

South Australia
Hyperlipoproteinemia Type II
South Africa
Brazil
Life Style
2 Citations (Scopus)

Homozygous familial hypercholesterolaemia in Vietnam: Case series, genetics and cascade testing of families

Truong, T. H., Kim, N. T., Nguyen, M. N. T., Pang, J., Hooper, A. J., Watts, G. F. & Do, D. L., Oct 2018, In : Atherosclerosis. 277, p. 392-398 7 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Vietnam
Genetic Testing
LDL Receptors
Mutation
1 Citation (Scopus)

Impact of ezetimibe on plasma lipoprotein(a) concentrations as monotherapy or in combination with statins: a systematic review and meta-analysis of randomized controlled trials

Sahebkar, A., Simental-Mendía, L. E., Pirro, M., Banach, M., Watts, G. F., Sirotri, C., Al-Rasadi, K. & Atkin, S. L., 1 Dec 2018, In : Scientific Reports. 8, 1, 17887.

Research output: Contribution to journalArticle

Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoprotein(a)
Meta-Analysis
Randomized Controlled Trials
Placebos
1 Citation (Scopus)

Improving the global care of familial hypercholesterolaemia: Starting the ball rolling

Ray, K. K. & Watts, G. F., 1 Oct 2018, In : Atherosclerosis. 277, p. 230-233 4 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)
Sodium Fluoride
Positron-Emission Tomography
Cardiovascular Diseases
Vascular Calcification
Calcium
4 Citations (Scopus)

Introducing the ‘Drucebo’ effect in statin therapy: a systematic review of studies comparing reported rates of statin-associated muscle symptoms, under blinded and open-label conditions

Penson, P. E., Mancini, G. B. J., Toth, P. P., Martin, S. S., Watts, G. F., Sahebkar, A., Mikhailidis, D. P. & Banach, M., 1 Dec 2018, In : Journal of Cachexia, Sarcopenia and Muscle. 9, 6, p. 1023-1033 11 p.

Research output: Contribution to journalArticle

Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Nocebo Effect
Muscles
Placebo Effect
Myalgia
1 Citation (Scopus)

Is Lipoprotein(a) Ready for Prime-Time Use in the Clinic?

Ellis, K. L. & Watts, G. F., 1 May 2018, In : Cardiology Clinics. 36, 2, p. 287-298 12 p.

Research output: Contribution to journalReview article

Lipoprotein(a)
Cardiovascular Diseases
Apoprotein(a)
Aortic Valve Stenosis
LDL Lipoproteins
2 Citations (Scopus)

Knowledge, awareness and practice regarding familial hypercholesterolaemia among primary care physicians in Malaysia: The importance of professional training

Azraii, A. B., Ramli, A. S., Ismail, Z., Abdul-Razak, S., Mohd-Kasim, N. A., Ali, N., Watts, G. F. & Nawawi, H., 1 Oct 2018, In : Atherosclerosis. 277, p. 508-516 9 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type II
Malaysia
Primary Care Physicians
Primary Health Care
Certification
2 Citations (Scopus)

Lipoprotein(a): lodestar for future clinical trials

Watts, G. F. & Boffa, M. B., 13 Oct 2018, In : The Lancet. 392, 10155, p. 1281-1282 2 p.

Research output: Contribution to journalComment/debate