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Gerald Watts

Winthrop Professor, DSc MB BS Lond., PhD W.Aust., DM S'ton, FRCP, FRACP

  • The University of Western Australia (M570), 35 Stirling Highway,

    6009 Perth

    Australia

  • 22114 Citations
  • 72 h-Index
1994 …2020
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Research Output 1994 2019

2019

A cross-national investigation of cardiovascular survival in homozygous familial hypercholesterolaemia: the Sino-Roman Study

Stefanutti, C., Pang, J., Di Giacomo, S., Wu, X., Wang, X., Morozzi, C., Watts, G. F. & Lin, J., Jul 2019, In : Journal of Clinical Lipidology. 13, 4, p. 608-617

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II
Blood Component Removal
LDL Cholesterol
Survival
Lipoproteins

A genetic risk score predicts coronary artery disease in familial hypercholesterolaemia: enhancing the precision of risk assessment

Ellis, K. L., Hooper, A. J., Pang, J., Chan, D. C., Burnett, J. R., Bell, D. A., Schultz, C. J., Moses, E. K. & Watts, G. F., 30 Sep 2019, In : Clinical Genetics.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II
Coronary Artery Disease
Life Style
Atherosclerosis
Coronary Vessels

A new approach to the diagnosis and treatment of atherosclerosis: the era of the liposome

Kiaie, N., Gorabi, A. M., Penson, P. E., Watts, G., Johnston, T. P., Banach, M. & Sahebkar, A., 13 Sep 2019, (Accepted/In press) In : Drug Discovery Today. 15 p.

Research output: Contribution to journal › Review article

Liposomes
Atherosclerosis
Cardiovascular Diseases
Therapeutics
Angina Pectoris

Apolipoprotein(a) Kinetics in Statin-Treated Patients With Elevated Plasma Lipoprotein(a) Concentration

Ma, L., Chan, D. C., Ooi, E. M. M., Marcovina, S. M., Barrett, P. H. R. & Watts, G. F., 1 Dec 2019, In : The Journal of clinical endocrinology and metabolism. 104, 12, p. 6247-6255 9 p.

Research output: Contribution to journal › Article

Apoprotein(a)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoprotein(a)
Plasmas
Kinetics

A window into the heart of familial hypercholesterolaemia in the community

Watts, G. F. & Pang, J., 1 May 2019, In : The Lancet Public Health. 4, 5, p. e216-e217

Research output: Contribution to journal › Editorial

Open Access

Clinical guidance on the contemporary use of proprotein convertase subtilisin/kexin type 9 monoclonal antibodies

Ward, N. C., Page, M. M. & Watts, G. F., 1 Apr 2019, In : Diabetes, Obesity and Metabolism. 21, S1, p. 52-62 11 p.

Research output: Contribution to journal › Article

LDL Cholesterol
Monoclonal Antibodies
Cardiovascular Diseases
Guidelines
Hydroxymethylglutaryl-CoA Reductase Inhibitors
3 Citations (Scopus)

Comparative aspects of the care of familial hypercholesterolemia in the “Ten Countries Study”

Pang, J., Chan, D. C., Hu, M., Muir, L. A., Kwok, S., Charng, M. J., Florkowski, C. M., George, P. M., Lin, J., Loi, D. D., Marais, A. D., Nawawi, H. M., Gonzalez-Santos, L. E., Su, T. C., Truong, T. H., Santos, R. D., Soran, H., Tomlinson, B., Yamashita, S., Ademi, Z. & 1 othersWatts, G. F., Apr 2019, In : Journal of Clinical Lipidology. 13, 2, p. 287-300

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II
Delivery of Health Care
Genetic Testing
Education
Developing Countries
1 Citation (Scopus)

Dyslipidaemia in adults with type 1 diabetes-when to treat?

Lan, N. S. R., Fegan, P. G., Yeap, B. B., Bell, D. A. & Watts, G. F., Jan 2019, In : Diabetes/Metabolism Research and Reviews. 35, 1, 5 p., 3090.

Research output: Contribution to journal › Editorial

Editorial: New targets, treatments and trials for preventing and reversing atherosclerosis: the paradox of choice

Watts, G. F. & Stroes, E. S. G., 1 Dec 2019, In : Current Opinion in Lipidology. 30, 6, p. 417-418 2 p.

Research output: Contribution to journal › Editorial

2 Citations (Scopus)

Effect of Lipoprotein(a) on the Diagnosis of Familial Hypercholesterolemia: Does it Make a Difference in the Clinic?

Chan, D. C., Pang, J., Hooper, A. J., Bell, D. A., Burnett, J. R. & Watts, G. F., Oct 2019, In : Clinical Chemistry. 65, 10, p. 1258-1266

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II
Lipoprotein(a)
LDL Cholesterol
Cholesterol
Lipids

Effect of Statin Therapy on Arterial Wall Inflammation Based on 18F-FDG PET/CT: A Systematic Review and Meta-Analysis of Interventional Studies

Pirro, M., Simental-Mendia, L. E., Bianconi, V., Watts, G. F., Banach, M. & Sahebkar, A., Jan 2019, In : Journal of Clinical Medicine. 8, 1, 14 p., 118.

Research output: Contribution to journal › Review article

Open Access

Familial hypercholesterolaemia: a common cause of premature coronary disease in the community and a paradigm for the practice of precision medicine

Pang, J. & Watts, G., 2019, In : Tasman Medical Journal. 1, 2, p. 16-26

Research output: Contribution to journal › Review article

Precision Medicine
Hyperlipoproteinemia Type II
Coronary Disease
Genetic Testing
Dyslipidemias

FAMILIAL HYPERCHOLESTEROLAEMIA - TIME FOR A GREATER ROLE FOR PRIMARY CARE

Brett, T., Arnold-Reed, D., Ping-Delfos, W. C. S., Condon, C. & Watts, G. F., Aug 2019, In : Atherosclerosis. 287, p. E209-E209 1 p.

Research output: Contribution to journal › Abstract/Meeting Abstract

Fractional turnover of apolipoprotein(a) and apolipoprotein B-100 within plasma lipoprotein(a) particles in statin-treated patients with elevated and normal Lp(a) concentration

Ma, L., Chan, D. C., Ooi, E. M. M., Barrett, P. H. R. & Watts, G. F., 1 Jul 2019, In : Metabolism: clinical and experimental. 96, p. 8-11 4 p.

Research output: Contribution to journal › Article

Apolipoprotein B-100
Apoprotein(a)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoprotein(a)
Apolipoproteins B

Icosapent ethyl for dyslipidaemia in patients with diabetes and coronary artery disease: Act now to reduce it

Lan, N. S. R., Fegan, P. G., Yeap, B. B., Rankin, J. M. & Watts, G. F., 1 Jul 2019, In : Diabetes, Obesity and Metabolism. 21, 7, p. 1734-1736 3 p.

Research output: Contribution to journal › Article

Dyslipidemias
Coronary Artery Disease
Acute Coronary Syndrome
Cardiovascular Diseases
Hydroxymethylglutaryl-CoA Reductase Inhibitors

Identifying Perceptions and Preferences of the General Public Concerning Universal Screening of Children for Familial Hypercholesterolaemia

Bowman, F. L., Molster, C. M., Lister, K. J., Bauskis, A. T., Garton-Smith, J., Vickery, A. W., Watts, G. F. & Martin, A. C., 22 Jul 2019, In : Public Health Genomics.

Research output: Contribution to journal › Article

Open Access
Hyperlipoproteinemia Type II
Inborn Genetic Diseases
Genomics
Coronary Disease
Immunization
2 Citations (Scopus)

Impact of PCSK9 inhibitors on plasma lipoprotein(a) concentrations with or without a background of niacin therapy

Warden, B. A., Minnier, J., Watts, G. F., Fazio, S. & Shapiro, M. D., 26 Apr 2019, In : Journal of Clinical Lipidology.

Research output: Contribution to journal › Article

Lipoprotein(a)
Niacin
Group Psychotherapy
Therapeutics
Proprotein Convertase 9

Implementing simple algorithms to improve glucose and lipid management in people with diabetes and acute coronary syndrome

Lan, N. S. R., Fegan, P. G., Rankin, J. M., Bell, D. A., Watts, G. F. & Yeap, B. B., 31 Jul 2019, In : Diabetic Medicine. 9 p.

Research output: Contribution to journal › Article

Acute Coronary Syndrome
Prescriptions
Symporters
Lipids
Blood Glucose
2 Citations (Scopus)

Improving the detection of familial hypercholesterolaemia

Lan, N. S. R., Martin, A. C., Brett, T., Watts, G. F. & Bell, D. A., Feb 2019, In : Pathology. 51, 2, p. 213-221 9 p.

Research output: Contribution to journal › Review article

LDL-C LOWERING AMONG PATIENTS WITH LDL-C ABOVE 4.9 MMOL/L AND FEATURES SUGGESTING A GENETIC VULNERABILITY TO CARDIOVASCULAR DISEASE: ANALYSES FROM THE 4S TRIAL

Vallejo-Vaz, A. J., Packard, C. J., Ference, B. A., Santos, R. D., Kastelein, J. J., Stein, E. A., Catapano, A. L., Pedersen, T. R., Watts, G. F. & Ray, K. K., Aug 2019, In : Atherosclerosis. 287, p. E6-E6 1 p.

Research output: Contribution to journal › Abstract/Meeting Abstract

Lipid management in people with peripheral artery disease

Golledge, J., Ward, N. C. & Watts, G. F., 1 Dec 2019, In : Current Opinion in Lipidology. 30, 6, p. 470-476 7 p.

Research output: Contribution to journal › Article

Peripheral Arterial Disease
LDL Cholesterol
Lipids
Myocardial Infarction
Lipoprotein(a)
1 Citation (Scopus)

Lipoprotein (a) and Low-density lipoprotein apolipoprotein B metabolism following apheresis in patients with elevated lipoprotein(a) and coronary artery disease

Ma, L., Waldmann, E., Ooi, E. M. M., Chan, D. C., Barrett, H. P. R., Watts, G. F. & Parhofer, K. G., Feb 2019, In : European Journal of Clinical Investigation. 49, 2, p. e13053

Research output: Contribution to journal › Article

Blood Component Removal
Lipoprotein(a)
Apolipoproteins B
LDL Lipoproteins
Metabolism
3 Citations (Scopus)

Lipoprotein(a) as a risk factor for calcific aortic valvulopathy in heterozygous familial hypercholesterolemia

Vuorio, A., Watts, G. F. & Kovanen, P. T., Feb 2019, In : Atherosclerosis. 281, p. 25-30 6 p.

Research output: Contribution to journal › Review article

3 Citations (Scopus)

Lipoprotein(a) Particle Production as a Determinant of Plasma Lipoprotein(a) Concentration Across Varying Apolipoprotein(a) Isoform Sizes and Background Cholesterol-Lowering Therapy

Chan, D. C., Watts, G. F., Coll, B., Wasserman, S. M., Marcovina, S. M. & Barrett, P. H. R., 2 Apr 2019, In : Journal of the American Heart Association. 8, 7, p. e011781

Research output: Contribution to journal › Article

Open Access
Apoprotein(a)
Lipoprotein(a)
Protein Isoforms
Cholesterol
Therapeutics
3 Citations (Scopus)

Loneliness in psychotic illness and its association with cardiometabolic disorders

Badcock, J. C., Mackinnon, A., Waterreus, A., Watts, G. F., Castle, D., McGrath, J. J. & Morgan, V. A., Feb 2019, In : Schizophrenia Research. 204, p. 90-95 6 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

PCSK9 inhibition 2018: riding a new wave of coronary prevention

Ward, N. C., Page, M. M. & Watts, G. F., 31 Jan 2019, In : Clinical Science. 133, 2, p. 205-224 20 p.

Research output: Contribution to journal › Review article

2 Citations (Scopus)

PCSK9 in HIV infection: New opportunity or red herring?

Ruscica, M., Watts, G. F. & Sirtori, C. R., 1 May 2019, In : Atherosclerosis. 284, p. 216-217 2 p.

Research output: Contribution to journal › Editorial

3 Citations (Scopus)

PCSK9 monoclonal antibodies and lipoprotein apheresis for lowering lipoprotein(a): making choices in an era of RNA-based therapies

Ruscica, M., Watts, G. F. & Sirtori, C. R., Jun 2019, In : European Journal of Preventive Cardiology. 26, 9, p. 998-1000 3 p.

Research output: Contribution to journal › Editorial

1 Citation (Scopus)

Postprandial Hypertriglyceridaemia Revisited in the Era of Non-fasting Lipid Profiles: Executive Summary of a 2019 Expert Panel Statement

Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, A., Tentolouris, N. & Nordestgaard, B. G., 1 Jan 2019, In : Current Vascular Pharmacology. 17, 5, p. 538-540 3 p.

Research output: Contribution to journal › Article

Open Access
8 Citations (Scopus)

Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text

Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, A., Tentolouris, N. & Nordestgaard, B. G., 1 Jan 2019, In : Current Vascular Pharmacology. 17, 5, p. 498-514 17 p.

Research output: Contribution to journal › Article

Hypertriglyceridemia
Lipids
Fats
Fasting
Triglycerides
2 Citations (Scopus)

Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review

Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, A., Tentolouris, N. & Nordestgaard, B. G., 1 Jan 2019, In : Current Vascular Pharmacology. 17, 5, p. 515-537 23 p.

Research output: Contribution to journal › Article

Hypertriglyceridemia
Lipids
Triglycerides
Meals
Age Factors

Potential utility of the SAFEHEART risk equation for rationalising the use of PCSK9 monoclonal antibodies in adults with heterozygous familial hypercholesterolemia

Pérez de Isla, L., Ray, K. K., Watts, G. F., Santos, R. D., Alonso, R., Muñiz-Grijalvo, O., Diaz-Diaz, J. L., Badimon, L., Catapano, A. L. & Mata, P., 1 Jul 2019, In : Atherosclerosis. 286, p. 40-45 6 p.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II
Monoclonal Antibodies
LDL Cholesterol
Numbers Needed To Treat
Therapeutics

Predicting intention to participate in self-management behaviors in patients with Familial Hypercholesterolemia: A cross-national study

Hagger, M. S., Hamilton, K., Hardcastle, S. J., Hu, M., Kwok, S., Lin, J., Nawawi, H. M., Pang, J., Santos, R. D., Soran, H., Su, T., Tomlinson, B. & Watts, G. F., Dec 2019, In : Social Science & Medicine. 242, 112591.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Recent advances in synthetic pharmacotherapies for dyslipidaemias

Sirtori, C. R., Yamashita, S., Francesca Greco, M., Corsini, A., F Watts, G. & Ruscica, M., 6 May 2019, In : European Journal of Preventive Cardiology.

Research output: Contribution to journal › Review article

Dyslipidemias
LDL Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypertriglyceridemia
Drug Therapy

Residual vascular risk in diabetes – Will the SPPARM alpha concept hold the key?

International Atherosclerosis Society/R3i Foundation Consensus Panel, 1 Jul 2019, In : Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 13, 4, p. 2723-2725 3 p.

Research output: Contribution to journal › Review article

Response by Ward et al to Letter Regarding Article, "statin Toxicity: Mechanistic Insights and Clinical Implications"

Ward, N. C., Watts, G. F. & Eckel, R. H., 7 Jun 2019, In : Circulation Research. 124, 12, p. e121-e122

Research output: Contribution to journal › Letter

9 Citations (Scopus)

Safety of red yeast rice supplementation: A systematic review and meta-analysis of randomized controlled trials

Lipid Blood Pressure Meta-Anal & ILEP, May 2019, In : Pharmacological Research. 143, p. 1-16 16 p.

Research output: Contribution to journal › Review article

Simon Broome confirms that the IAS definition of severe familial hypercholesterolemia predicts coronary mortality in patients with FH

Santos, R. D. & Watts, G. F., Feb 2019, In : Atherosclerosis. 281, p. 145-147 3 p.

Research output: Contribution to journal › Editorial

12 Citations (Scopus)

Statin Toxicity

Ward, N. C., Watts, G. F. & Eckel, R. H., 18 Jan 2019, In : Circulation Research. 124, 2, p. 328-350 23 p.

Research output: Contribution to journal › Article

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Muscles
Primary Prevention
Secondary Prevention
LDL Cholesterol
1 Citation (Scopus)

Status of PCSK9 Monoclonal Antibodies in Australia

Scherer, D. J., Nelson, A. J., O'Brien, R., Kostner, K. M., Hare, D. L., Colquhoun, D. M., Barter, P. J., Aylward, P., Nicholls, S. J. & Watts, G. F., 1 Oct 2019, In : Heart Lung and Circulation. 28, 10, p. 1571-1579 9 p.

Research output: Contribution to journal › Review article

Monoclonal Antibodies
Hyperlipoproteinemia Type II
Hypercholesterolemia
LDL Cholesterol
Prescriptions
1 Citation (Scopus)

The effects of omega-3 fatty acid supplementation upon interleukin-12 and interleukin-18 in chronic kidney disease patients

Yong, K., Mori, T., Chew, G., Beilin, L. J., Puddey, I., Watts, G. F., Irish, A., Dogra, G., Boudville, N. & Lim, W., Sep 2019, In : Journal of Renal Nutrition. 29, 5, p. 377-385 9 p.

Research output: Contribution to journal › Article

Interleukin-18
Omega-3 Fatty Acids
Interleukin-12
Chronic Renal Insufficiency
C-Reactive Protein

The relationship between pulse pressure and inflammation with left ventricular diastolic dysfunction in chronic kidney disease patients

Yong, K., Mori, T., Chew, G., Beilin, L. J., Puddey, I., Watts, G., Dogra, G., Boudville, N. & Lim, W., 12 Feb 2019, In : Internal Medicine Journal. 49, 2, p. 240-247

Research output: Contribution to journal › Article

Left Ventricular Dysfunction
Chronic Renal Insufficiency
Interleukin-18
Interleukin-12
Blood Pressure
3 Citations (Scopus)

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARM) paradigm: conceptual framework and therapeutic potential: A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

Fruchart, J-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Despres, J-P., Duriez, P., Eckel, R. H., Ezhov, M. V., Farnier, M., Ginsberg, H. N., Hermans, M. P., Ishibashi, S., Karpe, F., Kodama, T., Koenig, W. & 35 othersKrempf, M., Lim, S., Lorenzatti, A. J., McPherson, R., Millan Nunez-Cortes, J., Nordestgaard, B. G., Ogawa, H., Packard, C. J., Plutzky, J., Ponte-Negretti, C. I., Pradhan, A., Ray, K. K., Reiner, Z., Ridker, P. M., Ruscica, M., Sadikot, S., Shimano, H., Sritara, P., Stock, J. K., Su, T-C., Susekov, A. V., Tartar, A., Taskinen, M-R., Tenenbaum, A., Tokgozoglu, L. S., Tomlinson, B., Tybjaerg-Hansen, A., Valensi, P., Vrablik, M., Wahli, W., Watts, G. F., Yamashita, S., Yokote, K., Zambon, A. & Libby, P., 4 Jun 2019, In : Cardiovascular Diabetology. 18, 1, 20 p., 71.

Research output: Contribution to journal › Review article

Open Access

To test, or not to test: that is the question for the future of lipoprotein(a)

Ellis, K. L., Chakraborty, A., Moses, E. K. & Watts, G. F., 3 Apr 2019, In : Expert Review of Cardiovascular Therapy. 17, 4, p. 241-250 10 p.

Research output: Contribution to journal › Review article

Lipoprotein(a)
Cardiovascular Diseases
Guidelines
Genetically Modified Animals
Expert Testimony
6 Citations (Scopus)

Value of Measuring Lipoprotein(a) During Cascade Testing for Familial Hypercholesterolemia

Ellis, K. L., Pérez de Isla, L., Alonso, R., Fuentes, F., Watts, G. F. & Mata, P., 12 Mar 2019, In : Journal of the American College of Cardiology. 73, 9, p. 1029-1039 11 p.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II
Lipoprotein(a)
Cardiovascular Diseases

What's new on therapies for elevated lipoprotein(a)

Ward, N. C., Schultz, C. J. & Watts, G. F., 3 Jun 2019, In : Expert Review of Clinical Pharmacology. 12, 6, p. 495-499 5 p.

Research output: Contribution to journal › Editorial

Lipoprotein(a)
Software
Molecular Sequence Annotation
Protein Databases
Peptides
2018
10 Citations (Scopus)
192 Downloads (Pure)

A comparative analysis of phenotypic predictors of mutations in familial hypercholesterolemia

Chan, D. C., Pang, J., Hooper, A. J., Bell, D. A., Bates, T. R., Burnett, J. R. & Watts, G. F., 1 Apr 2018, In : The Journal of clinical endocrinology and metabolism. 103, 4, p. 1704-1714

Research output: Contribution to journal › Article

Open Access
File
Hyperlipoproteinemia Type II
Lipids
Mutation
Early Diagnosis
Xanthomatosis

Acute Impact of Different Exercise Modalities on Arterial and Platelet Function

Haynes, A., Linden, M. D., Robey, E., Watts, G. F., Barrett, P. H. R., Naylor, L. H. & Green, D. J., 1 Apr 2018, In : Medicine & Science in Sports & Exercise. 50, 4, p. 785–791

Research output: Contribution to journal › Article

Blood Platelets
Exercise
Platelet Activation
Brachial Artery
Acute Coronary Syndrome
7 Citations (Scopus)

Association between phenotypic familial hypercholesterolaemia and telomere length in US adults: results from a multi-ethnic survey

Banach, M., Mazidi, M., Mikhailidis, D. P., Toth, P. P., Jozwiak, J., Rysz, J. & Watts, G. F., 21 Oct 2018, In : European Heart Journal. 39, 40, p. 3635-3640 6 p.

Research output: Contribution to journal › Article

Open Access
Hyperlipoproteinemia Type II
Telomere
Confidence Intervals
Nutrition Surveys
Lipids
4 Citations (Scopus)

Comparative Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition and Statins on Postprandial Triglyceride-Rich Lipoprotein Metabolism

Chan, D. C., Watts, G. F., Somaratne, R., Wasserman, S. M., Scott, R. & Barrett, P. H. R., Jul 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 7, p. 1644-1655 12 p.

Research output: Contribution to journal › Article

Open Access
Apolipoprotein B-48
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoproteins
Triglycerides
Apolipoprotein B-100