Gerald Watts &ndash; Research Output

2019

A cross-national investigation of cardiovascular survival in homozygous familial hypercholesterolaemia: the Sino-Roman Study

Stefanutti, C., Pang, J., Di Giacomo, S., Wu, X., Wang, X., Morozzi, C., Watts, G. F. & Lin, J., 12 May 2019, In : Journal of Clinical Lipidology.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II

Blood Component Removal

LDL Cholesterol

Survival

Lipoproteins

A window into the heart of familial hypercholesterolaemia in the community

Watts, G. F. & Pang, J., 1 May 2019, In : The Lancet Public Health. 4, 5, p. e216-e217

Research output: Contribution to journal › Editorial

Open Access

Clinical guidance on the contemporary use of proprotein convertase subtilisin/kexin type 9 monoclonal antibodies

Ward, N. C., Page, M. M. & Watts, G. F., 1 Apr 2019, In : Diabetes, Obesity and Metabolism. 21, S1, p. 52-62 11 p.

Research output: Contribution to journal › Article

LDL Cholesterol

Monoclonal Antibodies

Cardiovascular Diseases

Guidelines

Hydroxymethylglutaryl-CoA Reductase Inhibitors

1 Citation (Scopus)

Comparative aspects of the care of familial hypercholesterolemia in the “Ten Countries Study”

Pang, J., Chan, D. C., Hu, M., Muir, L. A., Kwok, S., Charng, M. J., Florkowski, C. M., George, P. M., Lin, J., Loi, D. D., Marais, A. D., Nawawi, H. M., Gonzalez-Santos, L. E., Su, T. C., Truong, T. H., Santos, R. D., Soran, H., Tomlinson, B., Yamashita, S., Ademi, Z. & 1 othersWatts, G. F., Apr 2019, In : Journal of Clinical Lipidology. 13, 2, p. 287-300

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II

Delivery of Health Care

Genetic Testing

Education

Developing Countries

1 Citation (Scopus)

Dyslipidaemia in adults with type 1 diabetes-when to treat?

Lan, N. S. R., Fegan, P. G., Yeap, B. B., Bell, D. A. & Watts, G. F., Jan 2019, In : Diabetes/Metabolism Research and Reviews. 35, 1, 5 p., 3090.

Research output: Contribution to journal › Editorial

Effect of Lipoprotein(a) on the Diagnosis of Familial Hypercholesterolemia: Does it Make a Difference in the Clinic?

Chan, D. C., Pang, J., Hooper, A. J., Bell, D. A., Burnett, J. R. & Watts, G. F., 2019, In : Clinical Chemistry. p. clinchem.2019.306738

Research output: Contribution to journal › Article

Effect of Statin Therapy on Arterial Wall Inflammation Based on 18F-FDG PET/CT: A Systematic Review and Meta-Analysis of Interventional Studies

Pirro, M., Simental-Mendia, L. E., Bianconi, V., Watts, G. F., Banach, M. & Sahebkar, A., Jan 2019, In : Journal of Clinical Medicine. 8, 1, 14 p., 118.

Research output: Contribution to journal › Review article

Open Access

Fractional turnover of apolipoprotein(a) and apolipoprotein B-100 within plasma lipoprotein(a) particles in statin-treated patients with elevated and normal Lp(a) concentration

Ma, L., Chan, D. C., Ooi, E. M. M., Barrett, P. H. R. & Watts, G. F., 1 Jul 2019, In : Metabolism: clinical and experimental. 96, p. 8-11 4 p.

Research output: Contribution to journal › Article

Apolipoprotein B-100

Apoprotein(a)

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Lipoprotein(a)

Apolipoproteins B

Icosapent ethyl for dyslipidaemia in patients with diabetes and coronary artery disease: Act now to reduce it

Lan, N. S. R., Fegan, P. G., Yeap, B. B., Rankin, J. M. & Watts, G. F., 1 Jul 2019, In : Diabetes, Obesity and Metabolism. 21, 7, p. 1734-1736 3 p.

Research output: Contribution to journal › Article

Dyslipidemias

Coronary Artery Disease

Acute Coronary Syndrome

Cardiovascular Diseases

Hydroxymethylglutaryl-CoA Reductase Inhibitors

1 Citation (Scopus)

Impact of PCSK9 inhibitors on plasma lipoprotein(a) concentrations with or without a background of niacin therapy

Warden, B. A., Minnier, J., Watts, G. F., Fazio, S. & Shapiro, M. D., 26 Apr 2019, In : Journal of Clinical Lipidology.

Research output: Contribution to journal › Article

Lipoprotein(a)

Niacin

Group Psychotherapy

Therapeutics

Proprotein Convertase 9

1 Citation (Scopus)

Improving the detection of familial hypercholesterolaemia

Lan, N. S. R., Martin, A. C., Brett, T., Watts, G. F. & Bell, D. A., Feb 2019, In : Pathology. 51, 2, p. 213-221 9 p.

Research output: Contribution to journal › Review article

1 Citation (Scopus)

Lipoprotein (a) and Low-density lipoprotein apolipoprotein B metabolism following apheresis in patients with elevated lipoprotein(a) and coronary artery disease

Ma, L., Waldmann, E., Ooi, E. M. M., Chan, D. C., Barrett, H. P. R., Watts, G. F. & Parhofer, K. G., Feb 2019, In : European Journal of Clinical Investigation. 49, 2, p. e13053

Research output: Contribution to journal › Article

Blood Component Removal

Lipoprotein(a)

Apolipoproteins B

LDL Lipoproteins

Metabolism

2 Citations (Scopus)

Lipoprotein(a) as a risk factor for calcific aortic valvulopathy in heterozygous familial hypercholesterolemia

Vuorio, A., Watts, G. F. & Kovanen, P. T., Feb 2019, In : Atherosclerosis. 281, p. 25-30 6 p.

Research output: Contribution to journal › Review article

Lipoprotein(a) Particle Production as a Determinant of Plasma Lipoprotein(a) Concentration Across Varying Apolipoprotein(a) Isoform Sizes and Background Cholesterol-Lowering Therapy

Chan, D. C., Watts, G. F., Coll, B., Wasserman, S. M., Marcovina, S. M. & Barrett, P. H. R., 2 Apr 2019, In : Journal of the American Heart Association. 8, 7, p. e011781

Research output: Contribution to journal › Article

Open Access

Apoprotein(a)

Lipoprotein(a)

Protein Isoforms

Cholesterol

Therapeutics

3 Citations (Scopus)

Loneliness in psychotic illness and its association with cardiometabolic disorders

Badcock, J. C., Mackinnon, A., Waterreus, A., Watts, G. F., Castle, D., McGrath, J. J. & Morgan, V. A., Feb 2019, In : Schizophrenia Research. 204, p. 90-95 6 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

PCSK9 inhibition 2018: riding a new wave of coronary prevention

Ward, N. C., Page, M. M. & Watts, G. F., 31 Jan 2019, In : Clinical Science. 133, 2, p. 205-224 20 p.

Research output: Contribution to journal › Review article

1 Citation (Scopus)

PCSK9 in HIV infection: New opportunity or red herring?

Ruscica, M., Watts, G. F. & Sirtori, C. R., 1 May 2019, In : Atherosclerosis. 284, p. 216-217 2 p.

Research output: Contribution to journal › Editorial

PCSK9 monoclonal antibodies and lipoprotein apheresis for lowering lipoprotein(a): making choices in an era of RNA-based therapies

Ruscica, M., Watts, G. F. & Sirtori, C. R., Jun 2019, In : European Journal of Preventive Cardiology. 26, 9, p. 998-1000 3 p.

Research output: Contribution to journal › Editorial

Potential utility of the SAFEHEART risk equation for rationalising the use of PCSK9 monoclonal antibodies in adults with heterozygous familial hypercholesterolemia

Pérez de Isla, L., Ray, K. K., Watts, G. F., Santos, R. D., Alonso, R., Muñiz-Grijalvo, O., Diaz-Diaz, J. L., Badimon, L., Catapano, A. L. & Mata, P., 1 Jul 2019, In : Atherosclerosis. 286, p. 40-45 6 p.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II

Monoclonal Antibodies

LDL Cholesterol

Numbers Needed To Treat

Therapeutics

4 Citations (Scopus)

Safety of red yeast rice supplementation: A systematic review and meta-analysis of randomized controlled trials

Lipid Blood Pressure Meta-Anal & ILEP, May 2019, In : Pharmacological Research. 143, p. 1-16 16 p.

Research output: Contribution to journal › Review article

Simon Broome confirms that the IAS definition of severe familial hypercholesterolemia predicts coronary mortality in patients with FH

Santos, R. D. & Watts, G. F., Feb 2019, In : Atherosclerosis. 281, p. 145-147 3 p.

Research output: Contribution to journal › Editorial

2 Citations (Scopus)

Statin Toxicity

Ward, N. C., Watts, G. F. & Eckel, R. H., 18 Jan 2019, In : Circulation Research. 124, 2, p. 328-350 23 p.

Research output: Contribution to journal › Article

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Muscles

Primary Prevention

Secondary Prevention

LDL Cholesterol

The effects of omega-3 fatty acid supplementation upon interleukin-12 and interleukin-18 in chronic kidney disease patients

Yong, K., Mori, T., Chew, G., Beilin, L. J., Puddey, I., Watts, G. F., Irish, A., Dogra, G., Boudville, N. & Lim, W., 2019, In : Journal of Renal Nutrition. 9 p.

Research output: Contribution to journal › Article

Interleukin-18

Omega-3 Fatty Acids

Interleukin-12

Chronic Renal Insufficiency

C-Reactive Protein

The relationship between pulse pressure and inflammation with left ventricular diastolic dysfunction in chronic kidney disease patients

Yong, K., Mori, T., Chew, G., Beilin, L. J., Puddey, I., Watts, G., Dogra, G., Boudville, N. & Lim, W., 12 Feb 2019, In : Internal Medicine Journal. 49, 2, p. 240-247

Research output: Contribution to journal › Article

Left Ventricular Dysfunction

Chronic Renal Insufficiency

Interleukin-18

Interleukin-12

Blood Pressure

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARM) paradigm: conceptual framework and therapeutic potential: A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

Fruchart, J-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Despres, J-P., Duriez, P., Eckel, R. H., Ezhov, M. V., Farnier, M., Ginsberg, H. N., Hermans, M. P., Ishibashi, S., Karpe, F., Kodama, T., Koenig, W. & 35 othersKrempf, M., Lim, S., Lorenzatti, A. J., McPherson, R., Millan Nunez-Cortes, J., Nordestgaard, B. G., Ogawa, H., Packard, C. J., Plutzky, J., Ponte-Negretti, C. I., Pradhan, A., Ray, K. K., Reiner, Z., Ridker, P. M., Ruscica, M., Sadikot, S., Shimano, H., Sritara, P., Stock, J. K., Su, T-C., Susekov, A. V., Tartar, A., Taskinen, M-R., Tenenbaum, A., Tokgozoglu, L. S., Tomlinson, B., Tybjaerg-Hansen, A., Valensi, P., Vrablik, M., Wahli, W., Watts, G. F., Yamashita, S., Yokote, K., Zambon, A. & Libby, P., 4 Jun 2019, In : Cardiovascular Diabetology. 18, 1, 20 p., 71.

Research output: Contribution to journal › Review article

Open Access

To test, or not to test: that is the question for the future of lipoprotein(a)

Ellis, K. L., Chakraborty, A., Moses, E. K. & Watts, G. F., 3 Apr 2019, In : Expert Review of Cardiovascular Therapy. 17, 4, p. 241-250 10 p.

Research output: Contribution to journal › Review article

Lipoprotein(a)

Cardiovascular Diseases

Guidelines

Genetically Modified Animals

Expert Testimony

2 Citations (Scopus)

Value of Measuring Lipoprotein(a) During Cascade Testing for Familial Hypercholesterolemia

Ellis, K. L., Pérez de Isla, L., Alonso, R., Fuentes, F., Watts, G. F. & Mata, P., 12 Mar 2019, In : Journal of the American College of Cardiology. 73, 9, p. 1029-1039 11 p.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II

Lipoprotein(a)

Cardiovascular Diseases

What's new on therapies for elevated lipoprotein(a)

Ward, N. C., Schultz, C. J. & Watts, G. F., 3 Jun 2019, In : Expert Review of Clinical Pharmacology. 12, 6, p. 495-499 5 p.

Research output: Contribution to journal › Editorial

Lipoprotein(a)

Software

Molecular Sequence Annotation

Protein Databases

Peptides

2018

8 Citations (Scopus)

42 Downloads (Pure)

A comparative analysis of phenotypic predictors of mutations in familial hypercholesterolemia

Chan, D. C., Pang, J., Hooper, A. J., Bell, D. A., Bates, T. R., Burnett, J. R. & Watts, G. F., 1 Apr 2018, In : The Journal of clinical endocrinology and metabolism. 103, 4, p. 1704-1714

Research output: Contribution to journal › Article

Open Access

File

Hyperlipoproteinemia Type II

Lipids

Mutation

Early Diagnosis

Xanthomatosis

Acute Impact of Different Exercise Modalities on Arterial and Platelet Function

Haynes, A., Linden, M. D., Robey, E., Watts, G. F., Barrett, P. H. R., Naylor, L. H. & Green, D. J., 1 Apr 2018, In : Medicine & Science in Sports & Exercise. 50, 4, p. 785–791

Research output: Contribution to journal › Article

Blood Platelets

Exercise

Platelet Activation

Brachial Artery

Acute Coronary Syndrome

5 Citations (Scopus)

Association between phenotypic familial hypercholesterolaemia and telomere length in US adults: results from a multi-ethnic survey

Banach, M., Mazidi, M., Mikhailidis, D. P., Toth, P. P., Jozwiak, J., Rysz, J. & Watts, G. F., 21 Oct 2018, In : European Heart Journal. 39, 40, p. 3635-3640 6 p.

Research output: Contribution to journal › Article

Open Access

Hyperlipoproteinemia Type II

Telomere

Confidence Intervals

Nutrition Surveys

Lipids

3 Citations (Scopus)

Comparative Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition and Statins on Postprandial Triglyceride-Rich Lipoprotein Metabolism

Chan, D. C., Watts, G. F., Somaratne, R., Wasserman, S. M., Scott, R. & Barrett, P. H. R., Jul 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 7, p. 1644-1655 12 p.

Research output: Contribution to journal › Article

Open Access

Apolipoprotein B-48

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Lipoproteins

Triglycerides

Apolipoprotein B-100

Controlled study of the effect of proprotein convertase subtilisin-kexin type 9 inhibition with evolocumab on lipoprotein(a) particle kinetics

Watts, G. F., Chan, D. C., Somaratne, R., Wasserman, S. M., Scott, R., Marcovina, S. M. & Barrett, P. H. R., 14 Jul 2018, In : European Heart Journal. 39, 27, p. 2577-2585 9 p.

Research output: Contribution to journal › Article

Lipoprotein(a)

Apoprotein(a)

AMG 145

Proprotein Convertase 9

Apolipoproteins B

Dyslipidemia

Chan, D. T., Irish, A. B. & Watts, G. F., 1 Jan 2018, Handbook of Chronic Kidney Disease Management. 2nd ed. Kluwer Academic Publishers, p. 192-216 25 p.

Research output: Chapter in Book/Conference paper › Chapter

Editorial introductions (in Current Opinion in Lipidology)

Stroes, E. S. G. & Watts, G. F., Dec 2018, In : Current Opinion in Lipidology. 29, 6, p. 433-433 1 p.

Research output: Contribution to journal › Editorial

11 Citations (Scopus)

Effects of Allopurinol on Endothelial Function: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials

Cicero, A. F. G., Pirro, M., Watts, G. F., Mikhailidis, D. P., Banach, M. & Sahebkar, A., 1 Jan 2018, In : Drugs. 78, 1, p. 99-109 11 p.

Research output: Contribution to journal › Review article

Allopurinol

Meta-Analysis

Dilatation

Randomized Controlled Trials

Placebos

2 Citations (Scopus)

Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia

Hagger, M. S., Hardcastle, S. J., Hu, M., Kwok, S., Lin, J., Nawawi, H. M., Pang, J., Santos, R. D., Soran, H., Su, T-C., Tomlinson, B. & Watts, G. F., Oct 2018, In : Atherosclerosis. 277, p. 493-501 9 p.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II

Therapeutics

Cross-Sectional Studies

Cholesterol

Demography

7 Citations (Scopus)

Elevated lipoprotein(a) and familial hypercholesterolemia in the coronary care unit: Between Scylla and Charybdis

Ellis, K. L., Pang, J., Chieng, D., Bell, D. A., Burnett, J. R., Schultz, C. J., Hillis, G. S. & Watts, G. F., Mar 2018, In : Clinical Cardiology. 41, 3, p. 378-384

Research output: Contribution to journal › Article

Coronary Care Units

Hyperlipoproteinemia Type II

Lipoprotein(a)

Coronary Artery Disease

Acute Coronary Syndrome

3 Citations (Scopus)

Elevated lipoprotein(a) and low-density lipoprotein cholesterol as predictors of the severity and complexity of angiographic lesions in patients with premature coronary artery disease

Chieng, D., Pang, J., Ellis, K. L., Hillis, G. S., Watts, G. F. & Schultz, C. J., 3 Apr 2018, In : Journal of Clinical Lipidology. 12, 4, p. 1019-1026

Research output: Contribution to journal › Article

Lipoprotein(a)

LDL Cholesterol

Coronary Artery Disease

Coronary Care Units

Hyperlipoproteinemia Type II

1 Citation (Scopus)

Fenofibrate effects on carotid artery intima-media thickness in adults with type 2 diabetes mellitus: A FIELD substudy

Harmer, J. A., Keech, A. C., Veillard, A. S., Skilton, M. R., Watts, G. F. & Celermajer, D. S., 1 Jul 2018, In : Diabetes Research and Clinical Practice. 141, p. 156-167 12 p.

Research output: Contribution to journal › Article

Fenofibrate

Carotid Intima-Media Thickness

Carotid Arteries

Type 2 Diabetes Mellitus

Dyslipidemias

9 Citations (Scopus)

62 Downloads (Pure)

Health literacy in familial hypercholesterolemia: A cross-national study

Hagger, M. S., Hardcastle, S. J., Hu, M., Kwok, S., Lin, J., Nawawi, H. M., Pang, J., Santos, R. D., Soran, H., Su, T-C., Tomlinson, B. & Watts, G. F., Jun 2018, In : European Journal of Cardiovascular Prevention & Rehabilitation. 25, 9, p. 936-943

Research output: Contribution to journal › Article

Open Access

File

Health Literacy

Hyperlipoproteinemia Type II

China

Malaysia

Hong Kong

2 Citations (Scopus)

Heterozygous familial hypercholesterolaemia in specialist centres in South Africa, Australia and Brazil: Importance of early detection and lifestyle advice

Pang, J., David Marais, A., Blom, D. J., Brice, B. C., Silva, P. R., Jannes, C. E., Pereira, A. C., Hooper, A. J., Ray, K. K., Santos, R. D. & Watts, G. F., Oct 2018, In : Atherosclerosis. 277, p. 470-476 7 p.

Research output: Contribution to journal › Article

South Australia

Hyperlipoproteinemia Type II

South Africa

Brazil

Life Style

2 Citations (Scopus)

Homozygous familial hypercholesterolaemia in Vietnam: Case series, genetics and cascade testing of families

Truong, T. H., Kim, N. T., Nguyen, M. N. T., Pang, J., Hooper, A. J., Watts, G. F. & Do, D. L., Oct 2018, In : Atherosclerosis. 277, p. 392-398 7 p.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II

Vietnam

Genetic Testing

LDL Receptors

Mutation

1 Citation (Scopus)

Impact of ezetimibe on plasma lipoprotein(a) concentrations as monotherapy or in combination with statins: a systematic review and meta-analysis of randomized controlled trials

Sahebkar, A., Simental-Mendía, L. E., Pirro, M., Banach, M., Watts, G. F., Sirotri, C., Al-Rasadi, K. & Atkin, S. L., 1 Dec 2018, In : Scientific Reports. 8, 1, 17887.

Research output: Contribution to journal › Article

Open Access

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Lipoprotein(a)

Meta-Analysis

Randomized Controlled Trials

Placebos

1 Citation (Scopus)

Improving the global care of familial hypercholesterolaemia: Starting the ball rolling

Ray, K. K. & Watts, G. F., 1 Oct 2018, In : Atherosclerosis. 277, p. 230-233 4 p.

Research output: Contribution to journal › Editorial

2 Citations (Scopus)

In search of the vulnerable patient or the vulnerable plaque: F-sodium fluoride positron emission tomography for cardiovascular risk stratification

Bellinge, J. W., Francis, R. J., Majeed, K., Watts, G. F. & Schultz, C. J., 10 Jul 2018, In : Journal of Nuclear Cardiology. 25, 5, p. 1774-1783

Research output: Contribution to journal › Review article

Sodium Fluoride

Positron-Emission Tomography

Cardiovascular Diseases

Vascular Calcification

Calcium

4 Citations (Scopus)

Introducing the ‘Drucebo’ effect in statin therapy: a systematic review of studies comparing reported rates of statin-associated muscle symptoms, under blinded and open-label conditions

Penson, P. E., Mancini, G. B. J., Toth, P. P., Martin, S. S., Watts, G. F., Sahebkar, A., Mikhailidis, D. P. & Banach, M., 1 Dec 2018, In : Journal of Cachexia, Sarcopenia and Muscle. 9, 6, p. 1023-1033 11 p.

Research output: Contribution to journal › Article

Open Access

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Nocebo Effect

Muscles

Placebo Effect

Myalgia

1 Citation (Scopus)

Is Lipoprotein(a) Ready for Prime-Time Use in the Clinic?

Ellis, K. L. & Watts, G. F., 1 May 2018, In : Cardiology Clinics. 36, 2, p. 287-298 12 p.

Research output: Contribution to journal › Review article

Lipoprotein(a)

Cardiovascular Diseases

Apoprotein(a)

Aortic Valve Stenosis

LDL Lipoproteins

2 Citations (Scopus)

Knowledge, awareness and practice regarding familial hypercholesterolaemia among primary care physicians in Malaysia: The importance of professional training

Azraii, A. B., Ramli, A. S., Ismail, Z., Abdul-Razak, S., Mohd-Kasim, N. A., Ali, N., Watts, G. F. & Nawawi, H., 1 Oct 2018, In : Atherosclerosis. 277, p. 508-516 9 p.

Research output: Contribution to journal › Article

Hyperlipoproteinemia Type II

Malaysia

Primary Care Physicians

Primary Health Care

Certification

2 Citations (Scopus)

Lipoprotein(a): lodestar for future clinical trials

Watts, G. F. & Boffa, M. B., 13 Oct 2018, In : The Lancet. 392, 10155, p. 1281-1282 2 p.

Research output: Contribution to journal › Comment/debate