Gavin Pinniger

Dr, BSc PhD W'gong

  • The University of Western Australia (M311), 35 Stirling Highway, Room 1.06A, Physiology Building, Perth campus

    6009 Perth

    Australia

  • 631 Citations
  • 14 h-Index
20002019
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Personal profile

Biography

Dr Gavin Pinniger completed his undergraduate and PhD studies in the Department of Biomedical Science at the University of Wollongong in New South Wales. He then received a Travelling Research Fellowship from The Wellcome Trust to conduct his post-doctoral research at the University of Bristol in the United Kingdom before coming to UWA.

Funding overview

NHMRC Project Grants
NHMRC Equipment Grants
Raine Priming Grant
UWA Research Grant

Current projects

• The susceptibility to ventilator-induced diaphragm dysfunction in the pre-term lamb.
• Skeletal muscle physiology - molecular mechanisms of stretch-induced force enhancement and adaptation to exercise-induced muscle damage;
• Physiological evaluation of therapeutic and genetic treatments for muscular dystrophy;
• The role of protein thiol oxidation and inflammatory cytokines in muscle weakness associated with injury, ageing and disease.

Collaborators
Prof Jane Pillow, Centre for Neonatal Research and Education, and School of Human Sciences, UWA.
Dr Anthony Bakker, School of Human Sciences, UWA
Assoc Prof Peter Arhtur, School of Molecular Sciences, UWA
Prof. Miranda Grounds, School of Human Sciences, UWA
Dr Kimberly Wang, School of Human Sciences & Telethon Kids Institute
Dr Alexander Larcombe, Telethon Kids Institute & Curtin University

Teaching overview

Dr Pinniger is the coordinator for PHYL3001 Physiology of Membranes, Muscles and Signalling.
He also teaches in the following courses:
PHYL3002 Physiology of Cardiovascular and Respiratory Systems
PHYL3003 Physiology of Nutrition and Metabolism
PHYL3004 Physiology of Integrated Organ Function
PHYL2002 Physiology of Cells
SCIE1106 Molecular Biology of the Cell
APHB5505 Advanced Studies in Physiology
APHB4003 Scientific Communication Part 1

Research

Dr Pinniger’s research focuses on the physiological investigation of skeletal muscle function in health and disease. He is particularly interested in the molecular mechanisms underlying muscle contraction and the evaluation of medical treatments for muscular weakness and diseases such as Duchenne muscular dystrophy. Dr Pinniger's recent research has focused on the effects of common, clinically relevant antenatal exposures on preterm diaphragm function.

Engagement

Local Representative for The Physiological Society 

https://www.physoc.org/

Keywords

  • Skeletal muscle physiology
  • Muscular dystrophy
  • Diaphragm dysfunction
  • Skeletal muscle damage
  • Muscle damage and inflammation
  • Neuromuscular physiology
  • Motor control
  • Preterm Birth

Fingerprint Dive into the research topics where Gavin Pinniger is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Diaphragm Medicine & Life Sciences
Muscles Medicine & Life Sciences
Inbred mdx Mouse Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Muscle Chemical Compounds
Duchenne Muscular Dystrophy Medicine & Life Sciences
Torque Medicine & Life Sciences
Diaphragms Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2000 2019

1 Citation (Scopus)

Dysferlin-deficiency has greater impact on function of slow muscles, compared with fast, in aged BLAJ mice

Lloyd, E. M., Xu, H., Murphy, R. M., Grounds, M. D. & Pinniger, G. J., 1 Apr 2019, In : PLoS One. 14, 4, e0214908.

Research output: Contribution to journalArticle

Open Access
Muscle
Muscles
muscles
mice
Protein Isoforms
Diaphragm
Growth
Fetal Development
Baths
Fatigue
1 Citation (Scopus)
Diaphragm
Gestational Age
Lipopolysaccharides
Inflammation
Myosin Heavy Chains
186 Downloads (Pure)

The mechanism of selenium-induced skeletal muscle dysfunction and weakness

Wilson, T., 2018, (Unpublished)

Research output: ThesisMaster's Thesis

File
Muscle Weakness
Contracture
Selenium
Skeletal Muscle
Ryanodine Receptor Calcium Release Channel

Projects 2008 2016