Gavin Pinniger

Dr, BSc PhD W'gong

  • The University of Western Australia (M311), 35 Stirling Highway, Room 1.06A, Physiology Building, Perth campus

    6009 Perth

    Australia

  • 409 Citations
  • 11 h-Index
20052019
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Personal profile

Biography

Dr Gavin Pinniger completed his undergraduate and PhD studies in the Department of Biomedical Science at the University of Wollongong in New South Wales. He then received a Travelling Research Fellowship from The Wellcome Trust to conduct his post-doctoral research at the University of Bristol in the United Kingdom before coming to UWA.

Funding overview

NHMRC Project Grants
NHMRC Equipment Grants
Raine Priming Grant
UWA Research Grant

Current projects

•The susceptibility to ventilator-induced diaphragm dysfunction in the pre-term lamb.
•Skeletal muscle physiology - molecular mechanisms of stretch-induced force enhancement and adaptation to exercise-induced muscle damage;
•Physiological evaluation of therapeutic and genetic treatments for muscular dystrophy;
•The role of protein thiol oxidation and inflammatory cytokines in muscle weakness associated with injury, ageing and disease.

Collaborators
Prof Jane Pillow, Centre for Neonatal Research and Education, and School of Anatomy, Physiology and Human Biology, UWA.
Dr Anthony Bakker, School of Anatomy, Physiology and Human Biology, UWA
Assoc Prof Peter Arhtur, School of Chemistry and Biochemistry, UWA
Prof. Miranda Grounds, School of Anatomy, Physiology and Human Biology, UWA
Prof. Steve Wilton & Dr Sue Fletcher, Australian Neuromuscular Research Institute (ANRI)

Teaching overview

Dr Pinniger is the coordinator for PHYL3001 Physiology of Membranes, Muscles and Signalling.
He also teaches in the following courses:
PHYL3002 Physiology of Cardiovascular and Respiratory Systems
PHYL3003 Physiology of Nutrition and Metabolism
PHYL2002 Physiology of Cells
SCIE1106 Molecular Biology of the Cell
APHB5505 Advanced Studies in Physiology
APHB4003 Scientific Communication Part 1

Research

Dr Pinniger’s research focuses on the physiological investigation of skeletal muscle function in health and disease. He is particularly interested in the molecular mechanisms underlying muscle contraction and the evaluation of medical treatments for muscular weakness and diseases such as Duchenne muscular dystrophy. Dr Pinniger's recent research has focused on the effects of common, clinically relevant antenatal exposures on preterm diaphragm function.

Keywords

  • Skeletal muscle physiology
  • Muscular dystrophy
  • Skeletal muscle damage
  • Muscle damage and inflammation
  • Neuromuscular physiology
  • Motor control

Fingerprint Dive into the research topics where Gavin Pinniger is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Diaphragm Medicine & Life Sciences
Muscles Medicine & Life Sciences
Inbred mdx Mouse Medicine & Life Sciences
Duchenne Muscular Dystrophy Medicine & Life Sciences
Muscle Chemical Compounds
Diaphragms Chemical Compounds
Myosin Heavy Chains Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2019

Dysferlin-deficiency has greater impact on function of slow muscles, compared with fast, in aged BLAJ mice

Lloyd, E. M., Xu, H., Murphy, R. M., Grounds, M. D. & Pinniger, G. J., 1 Apr 2019, In : PLoS One. 14, 4, e0214908.

Research output: Contribution to journalArticle

Open Access
Muscle
Muscles
muscles
mice
Protein Isoforms
1 Citation (Scopus)
Diaphragm
Gestational Age
Lipopolysaccharides
Inflammation
Myosin Heavy Chains
63 Downloads (Pure)

The mechanism of selenium-induced skeletal muscle dysfunction and weakness

Wilson, T., 2018, (Unpublished)

Research output: ThesisMaster's Thesis

File
Muscle Weakness
Contracture
Selenium
Skeletal Muscle
Ryanodine Receptor Calcium Release Channel
4 Citations (Scopus)
Open Access
Inbred mdx Mouse
Taurine
taurine
mice
Growth

Projects 2008 2016