Gavin Flematti

Dr, PhD W.Aust.

  • The University of Western Australia (M313), 35 Stirling Highway, Room 417, Bayliss Building, Perth campus

    6009 Crawley

    Australia

  • 2560 Citations
  • 26 h-Index
20012020
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Research Output 2001 2018

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Article
2018
Open Access
Triple Negative Breast Neoplasms
Porifera
Cell Cycle Checkpoints
Apoptosis
Breast Neoplasms

Procyanidin A2 in the Australian plant Alectryon oleifolius has anthelmintic activity against equine cyathostomins in vitro

Payne, S. E., Flematti, G. R., Reeder, A., Kotze, A. C., Durmic, Z. & Vercoe, P. E. 15 Jan 2018 In : Veterinary Parasitology. 249, p. 63-69 7 p.

Research output: Contribution to journalArticle

Cyathostominae
Anthelmintics
anthelmintics
Horses
horses
2017
8 Citations

Complex Sexual Deception in an Orchid Is Achieved by Co-opting Two Independent Biosynthetic Pathways for Pollinator Attraction

Xu, H., Bohman, B., Wong, D. C. J., Rodriguez-Delgado, C., Scaffidi, A., Flematti, G. R., Phillips, R. D., Pichersky, E. & Peakall, R. 10 Jul 2017 In : Current Biology. 27, 13, p. 1867-1877.e5

Research output: Contribution to journalArticle

citral
citronellol
Biosynthetic Pathways
Deception
geranial
2 Citations

Establishing alighting preferences and species transmission differences for Pea seed-borne mosaic virus aphid vectors

Congdon, B. S., Coutts, B. A., Renton, M., Flematti, G. R. & Jones, R. A. C. 15 Sep 2017 In : Virus Research. 241, p. 145-155 11 p.

Research output: Contribution to journalArticle

Mosaic Viruses
Aphids
Peas
Seeds
Vicia faba

Nickel-Catalyzed C-N Cross-Coupling of Primary Imines with Subsequent InSitu [2+2] Cycloaddition or Alkylation

Power, D. J., Jones, K. D., Kampmann, S. S., Flematti, G. R. & Stewart, S. G. 9 Oct 2017 In : Asian Journal of Organic Chemistry. 6, 12

Research output: Contribution to journalArticle

Imines
Cycloaddition
Alkylation
Nickel
beta-Lactams

Practical one-pot stereospecific preparation of vicinal and 1,3-diols

Bohman, B., Flematti, G. R. & Unelius, C. R. 4 Jan 2017 In : Tetrahedron Letters. 58, 1, p. 75-77 3 p.

Research output: Contribution to journalArticle

Pheromones
Beetles
Esters
Acetals
Chromatography
7 Citations

The Spider Orchid Caladenia crebra Produces Sulfurous Pheromone Mimics to Attract its Male Wasp Pollinator

Bohman, B., Phillips, R. D., Flematti, G. R., Barrow, R. A. & Peakall, R. 10 Jul 2017 In : Angewandte Chemie. 56, 29, p. 8455-8458 4 p.

Research output: Contribution to journalArticle

Open Access
File
2016
3 Citations
Benzene
Biological Products
Anthraquinones
Enantiomers
Bioactivity
4 Citations

A new selective fluorescent probe based on tamoxifen

Ho, L., Thomas, L., Mclaughlin, R. A., Flematti, G. & Fuller, B. 15 Oct 2016 In : Bioorganic and Medicinal Chemistry Letters. 26, 20, p. 4879-4883 5 p.

Research output: Contribution to journalArticle

Tamoxifen
Fluorescent Dyes
Estrogen Receptors
Breast Neoplasms
Cells
1 Citations

Bioactive fractions from the pasture legume Biserrula pelecinus L. have an anti-methanogenic effect against key rumen methanogens

Banik, B. K., Durmic, Z., Erskine, W., Revell, C. K., Vadhanabhuti, J., McSweeney, C. S., Padmanabha, J., Flematti, G. R., Algreiby, A. & Vercoe, P. E. 2016 In : Anaerobe. 39, p. 173-182 10 p.

Research output: Contribution to journalArticle

Archaea
Rumen
Fabaceae
Methane
Ruminants
9 Citations

Hit-to-lead optimization of a novel class of potent, broad-spectrum trypanosomacides

Russell, S. , Rahmani, R. , Jones, A. J. , Newson, H. , Neilde, K. , Cotillo, I. , Khajouei, M. , Ferrins, L. , Qureishi, S. , Nguyen, N. , Martinez-Martinez, M. S. , Weaver, D. F. , Kaiser, M. , Riley, J. , Thomas, J. , De Rycker, M. , Read, K. D. , Flematti, G. , Ryan, E. , Tanghe, S. & 6 others Rodriguez, A., Charman, S. A., Kessler, A., Avery, V. M., Baell, J. B. & Piggott, M. Nov 2016 In : Journal of Medicinal Chemistry. 59, 21, p. 9686-9720 35 p.

Research output: Contribution to journalArticle

Open Access
File
Trypanosomiasis
Neglected Diseases
African Trypanosomiasis
Trypanosoma brucei brucei
Chagas Disease
2 Citations

Identification of the Cat Attractants Isodihydronepetalactone and Isoiridomyrmecin from Acalypha indica

Scaffidi, A., Algar, D., Bohman, B., Ghisalberti, E. & Flematti, G. 21 Jan 2016 In : Australian Journal of Chemistry. 69, 2, p. 169-173

Research output: Contribution to journalArticle

Open Access
File
Stereochemistry
Pharmaceutical Preparations
feral
isoiridomyrmecin
11 Citations

Karrikins identified in biochars indicate post-fire chemical cues can influence community diversity and plant development

Kochanek, J., Long, R., Lisle, A. T. & Flematti, G. 18 Aug 2016 In : PLoS One. 11, 8, p. 1-19

Research output: Contribution to journalArticle

Open Access
Social Planning
biochar
Plant Development
Cues
plant development
35 Citations

Lateral branching oxidoreductase acts in the final stages of strigolactone biosynthesis in Arabidopsis

Brewer, P. B., Yoneyama, K., Filardo, F., Meyers, E., Scaffidi, A., Frickey, T., Akiyama, K., Seto, Y., Dun, E. A., Cremer, J. E., Kerr, S. C., Waters, M. T., Flematti, G. R., Mason, M. G., Weiller, G., Yamaguchi, S., Nomura, T., Smith, S. M. & Beveridge, C. A. 31 May 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 22, p. 6301-6306

Research output: Contribution to journalArticle

Open Access
File
Arabidopsis
Oxidoreductases
Enzymes
Reverse Genetics
Dioxygenases
5 Citations
Open Access
reporter genes
leaf extracts
Arabidopsis
luciferase
genes
2015
4 Citations

A Direct Pre-screen for Marine Bacteria Producing Compounds Inhibiting Quorum Sensing Reveals Diverse Planktonic Bacteria that are Bioactive

Linthorne, J., Chang, B., Flematti, G., Ghisalberti, E. & Sutton, D. Feb 2015 In : Marine Biotechnology. 17, 1, p. 33-42

Research output: Contribution to journalArticle

Quorum Sensing
quorum sensing
Vibrio harveyi
Chromobacterium violaceum
Pseudoalteromonas
28 Citations
Open Access
Selaginellaceae
Selaginella
Arabidopsis
serine
complement
44 Citations

Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3

Zhao, L. H., Zhou, X. E., Yi, W., Wu, Z., Liu, Y., Kang, Y., Hou, L., De Waal, P. W., Li, S., Jiang, Y., Scaffidi, A., Flematti, G., Smith, S., Lam, V. Q., Griffin, P. R., Wang, Y., Li, J., Melcher, K. & Xu, H. E. 2015 In : Cell Research. 25, 11, p. 1219-1236

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Ligands
SKP Cullin F-Box Protein Ligases
Hormones
Structural Models
1 Citations

Identification of hydroxymethylpyrazines using mass spectrometry

Bohman, B., Flematti, G. & Barrow, R. A. Aug 2015 In : Journal of Mass Spectrometry. 50, 8, p. 987-993

Research output: Contribution to journalArticle

Pheromones
Pyrazines
Mass spectrometry
Biological Products
Isomers
2 Citations

Oxidation of hydroxymethylpyrazines and hydroxylated phenyl compounds in a gas chromatography inlet

Bohman, B. & Flematti, G. 21 Mar 2015 In : Analytical Methods. 7, 6, p. 2283-2286 4 p.

Research output: Contribution to journalArticle

Aldehydes
Gas chromatography
Oxidation
Mass spectrometry
Alcohols
13 Citations
6 Citations

The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity

Bythell-Douglas, R., Suttisansanee, U., Flematti, G., Challenor, M., Lee, M., Panjikar, S. K., Honek, J. F. & Bond, C. 2015 In : Chemistry - A European Journal. 21, 2, p. 541-544

Research output: Contribution to journalArticle

Lactoylglutathione Lyase
Crystal structure
Metals
Enzymes
Ions
2014
46 Citations

Discovery of pyrazines as pollinator sex pheromones and orchid semiochemicals: Implications for the evolution of sexual deception

Bohman, B., Phillips, R. D., Menz, M. H. M., Berntsson, B. W., Flematti, G., Barrow, R. A., Dixon, K. & Peakall, R. Aug 2014 In : New Phytologist. 203, 3, p. 939-952

Research output: Contribution to journalArticle

Pyrazines
Sex Attractants
pyrazines
semiochemicals
Pheromones
8 Citations

Ethynylbenzenoid metabolites of Antrodia camphorata: Synthesis and inhibition of TNF expression

Buccini, M., Punch, K. A., Kaskow, B., Flematti, G., Skelton, B., Abraham, L. & Piggott, M. 2014 In : Organic and Biomolecular Chemistry. 12, 7, p. 1100-1113

Research output: Contribution to journalArticle

Antrodia
necrosis
metabolites
Metabolites
Anti-Inflammatory Agents
1 Citations

Karrikins promote germination of physiologically dormant seeds of Chrysanthemoides monilifera ssp. monilifera (boneseed)

Reynolds, C. J., Long, R., Flematti, G., Cherry, H. & Turner, S. 5 Jan 2014 In : Weed Research. 54, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

Chrysanthemoides monilifera
germination
buried seeds
seed
weed
86 Citations

Rice cytochrome P450 MAX1 homologs catalyze distinct steps in strigolactone biosynthesis

Zhang, Y., Van Dijk, A. D. J., Scaffidi, A., Flematti, G., Hofmann, M., Charnikhova, T., Verstappen, F., Hepworth, J., Van Der Krol, S., Leyser, O., Smith, S., Zwanenburg, B., Al-Babili, S., Ruyter-Spira, C. & Bouwmeester, H. J. Dec 2014 In : Nature Chemical Biology. 10, 12, p. 1028-1033

Research output: Contribution to journalArticle

Cytochrome P-450 Enzyme System
Carotenoids
Growth
Enzymes
Dioxygenases
76 Citations
Open Access
stereoisomers
Stereoisomerism
Arabidopsis
plant response
Arabidopsis thaliana
50 Citations

The karrikin response system of Arabidopsis

Waters, M., Scaffidi, A., Sun, Y., Flematti, G. & Smith, S. Aug 2014 In : The Plant Journal. 79, 4, p. 623-631

Research output: Contribution to journalArticle

Arabidopsis
F-box proteins
photomorphogenesis
rice protein
Seeds
4 Citations

Volatile Combustion Products of Wood Attract Acanthocnemus nigricans (Coleoptera: Acanthocnemidae)

Paczkowski, S., Paczkowska, M., Dippel, S., Flematti, G. & Schütz, S. 2014 In : Journal of Insect Behavior. 27, 2, p. 228-238

Research output: Contribution to journalArticle

wood products
combustion
beetle
Coleoptera
eugenol
2013
11 Citations

Acclimation-induced changes in cell membrane composition and influence on cryotolerance of in vitro shoots of native plant species

Funnekotter, B., Kaczmarczyk, A., Turner, S., Bunn, E., Zhou, W., Smith, S., Flematti, G. & Mancera, R. L. 2013 In : Plant Cell Tissue and Organ Culture. 114, p. 83-96

Research output: Contribution to journalArticle

50 Citations

Carlactone-independent seedling morphogenesis in Arabidopsis

Scaffidi, A., Waters, M., Ghisalberti, E., Dixon, K., Flematti, G. & Smith, S. 2013 In : PLANT JOURNAL. 76, 1, p. 9pp

Research output: Contribution to journalArticle

25 Citations

Harzianic acid: A novel siderophore from Trichoderma harzianum

Vinale, F., Nigro, M., Sivasithamparam, K., Flematti, G., Ghisalberti, E., Ruocco, M., Varlese, R., Marra, R., Lanzuise, S., Eid, A., Woo, S. L. & Lorito, M. 2013 In : FEMS Microbiology Letters. 347, 2, p. 123 - 129

Research output: Contribution to journalArticle

35 Citations

Karrikin and Cyanohydrin Smoke Signals Provide Clues to New Endogenous Plant Signalling Compounds

Flematti, G., Waters, M., Scaffidi, A., Merritt, D., Ghisalberti, E., Dixon, K. & Smith, S. 2013 In : Molecular Plant. 6, 1, p. 29-37

Research output: Contribution to journalArticle

Open Access
2 Citations
20 Citations

Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity

Golden, E., Paterson, R., Tie, A., Anandan, A., Flematti, G., Molla, G., Rosini, E., Pollegioni, L. & Vrielink, A. 2013 In : Biochemical Journal. 451, 2, p. 217 - 226

Research output: Contribution to journalArticle

24 Citations

The origins and mechanisms of karrikin signalling

Waters, M., Scaffidi, A., Flematti, G. & Smith, S. 2013 In : Current Opinion in Plant Biology. 16, p. 667-673

Research output: Contribution to journalArticle

29 Citations

The Structure of the Karrikin-Insensitive Protein (KAI2) in Arabidopsis thaliana

Bythell-Douglas, R., Waters, M., Scaffidi, A., Flematti, G., Smith, S. & Bond, C. 18 Jan 2013 In : PLoS One. 8, 1, p. 1-8

Research output: Contribution to journalArticle

Open Access
Hydrolases
hydrolases
Arabidopsis
Arabidopsis thaliana
Petunia
2012
25 Citations

Discovery of tetrasubstituted pyrazines as semiochemicals in a sexually deceptive orchid

Bohman, B., Jeffares, L., Flematti, G., Byrne, L., Skelton, B., Phillips, R., Dixon, K., Peakall, R. & Barrow, R. A. 2012 In : Journal of Natural Products. 75, p. 1589-1594

Research output: Contribution to journalArticle

44 Citations

Exploring the molecular mechanism of karrikins and strigolactones

Scaffidi, A., Waters, M., Bond, C., Dixon, K., Smith, S., Ghisalberti, E. & Flematti, G. 2012 In : Bioorganic & medicinal chemistry letters. 22, 11, p. 3743-3746

Research output: Contribution to journalArticle

Plant Growth Regulators
Crowns
Hydrolysis
butenolide
8 Citations

Inhibition of ruminal bacteria involved in lactic acid metabolism by extracts from Australian plants

Hutton, P. G., Durmic, Z., Ghisalberti, E., Flematti, G., Duncan, R. M., Carson, C., Riley, T. & Vercoe, P. 2012 In : Animal Feed Science and Technology. 176, p. 170-177

Research output: Contribution to journalArticle

8 Citations

Investigation of volatile organic biomarkers derived from Plasmodium falciparum in vitro

Wong, R., Flematti, G. & Davis, T. 7 Sep 2012 In : Malaria Journal. 11, 1, p. 314-323

Research output: Contribution to journalArticle

Open Access
Volatile Organic Compounds
Plasmodium falciparum
Biomarkers
Parasites
Malaria
15 Citations

Karrikins force a rethink of strigolactone mode of action

Waters, M., Scaffidi, A., Flematti, G. & Smith, S. 2012 In : Plant Signaling and Behavior. 7, 8, p. 969-972

Research output: Contribution to journalArticle

8 Citations

Mycotoxins produced by Fusarium spp. associated with Fusarium head blight of wheat in Western Australia

Tan, D. C., Flematti, G., Ghisalberti, E., Sivasithamparam, K., Chakraborty, S., Obanor, F., Jayasena, K. & Barbetti, M. 2012 In : MYCOTOXIN RESEARCH. 28, p. 89-96

Research output: Contribution to journalArticle

7 Citations

Parental environment changes the dormancy state and karrikinolide response of Brassica tournefortii seeds

Gorecki, M., Long, R., Flematti, G. & Stevens, J. 2012 In : Annals of Botany. 109, p. 1369-1378

Research output: Contribution to journalArticle

100 Citations

Regulation of Seed Germination and Seedling Growth by Chemical Signals from Burning Vegetation

Nelson, D., Flematti, G., Ghisalberti, E., Dixon, K. & Smith, S. 2012 In : Annual Review of Plant Biology. 63, p. 107-130

Research output: Contribution to journalArticle

4 Citations

Solar irradiation of the seed germination stimulant karrikinolide produces two novel head-to-head cage dimers

Scaffidi, A., Waters, M., Skelton, B., Bond, C., Sobolev, A., Bythell-Douglas, R., Mckinley, A., Dixon, K., Ghisalberti, E., Smith, S. & Flematti, G. 28 May 2012 In : Organic & Biomolecular Chemistry. 10, 20, p. 4069-4073

Research output: Contribution to journalArticle

stimulants
germination
Germination
Dimers
Seed
185 Citations

Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis

Waters, M., Nelson, D. C., Scaffidi, A., Flematti, G., Sun, Y., Dixon, K. & Smith, S. 2012 In : Development. 139, p. 1285-1295

Research output: Contribution to journalArticle

10 Citations

Stable triazolylphosphonate analogues of phosphohistidine

Mukai, S., Flematti, G., Byrne, L., Besant, P., Attwood, P. & Piggott, M. 2012 In : Amino acids. 22 November 2011, p. 18pp

Research output: Contribution to journalArticle

33 Citations

The discovery of 2-hydroxymethyl-3-(3-methylbutyl)-5-methylpyrazine: A semiochemical in orchid pollination

Bohman, B., Jeffares, L., Flematti, G., Phillips, R., Dixon, K., Peakall, R. & Barrow, R. A. 2012 In : Organic Letters. 14, p. 2576=2578

Research output: Contribution to journalArticle

2011
51 Citations

Burning vegetation produces cyanohydrins that liberate cyanide and stimulate seed germination

Flematti, G., Merritt, D., Piggott, M., Trengove, R. D., Smith, S., Dixon, K. & Ghisalberti, E. 2011 In : NATURE COMMUNICATIONS. 2, p. 6pp

Research output: Contribution to journalArticle

germination
Cyanides
cyanides
Germination
vegetation