Gavin Flematti

Dr, PhD W.Aust.

  • The University of Western Australia (M313), 35 Stirling Highway, Room 417, Bayliss Building, Perth campus

    6009 Crawley

    Australia

  • 2568 Citations
  • 26 h-Index
20012020
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Personal profile

Biography

Dr Gavin Flematti completed his undergraduate and PhD studies at UWA, followed by post-doctoral studies and a prestigious Australian Future Fellowship award at UWA. He currently holds a teaching and research position in the School of Chemistry and Biochemistry at UWA.

Funding overview

ARC Discovery Grants
ARC Linkage Grant
ARC Future Fellowship

Current projects

Collaborators

Dr Kingsley Dixon, Kings Park and Botanic Garden
Dr David Merritt, Kings Park and Botanic Garden
Dr Jason Stephens, Kings Park and Botanic Garden
A/Prof Emilio Ghisalberti, Chemistry UWA
Prof Steven Smith, UWA
Dr David Nelson, University of Georgia, USA
A/Prof Rob Trengove, Murdoch University

Teaching overview

CHEM2001 Core Chemical Concepts and Techniques
CHEM2003 Chemical Synthesis
MSCI4006 Advanced Techniques in Molecular Sciences

Research

Natural Products and Chemical Ecology

The primary research interest in the Flematti Lab is the isolation and identification of bioactive natural products. The specific activity of these compounds ranges from antibacterial and anticancer activity, through to organism defence and chemical communication. As well as traditional natural product extraction and isolation, we make use of sophisticated analytical instruments including HPLC, GC-MS, HPLC-MS and more recently GC-EAD/MS, to aid in the detection and isolation of bioactive compounds, which are characterised using NMR spectroscopy and high resolution MS techniques. Depending on the structure and function, interesting compounds are confirmed through chemical synthesis.

Keywords

  • Natural products and chemical ecology

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2007 2020

Research Output 2001 2018

Open Access
Triple Negative Breast Neoplasms
Porifera
Cell Cycle Checkpoints
Apoptosis
Breast Neoplasms

Procyanidin A2 in the Australian plant Alectryon oleifolius has anthelmintic activity against equine cyathostomins in vitro

Payne, S. E., Flematti, G. R., Reeder, A., Kotze, A. C., Durmic, Z. & Vercoe, P. E. 15 Jan 2018 In : Veterinary Parasitology. 249, p. 63-69 7 p.

Research output: Contribution to journalArticle

Cyathostominae
Anthelmintics
anthelmintics
Horses
horses
8 Citations

Complex Sexual Deception in an Orchid Is Achieved by Co-opting Two Independent Biosynthetic Pathways for Pollinator Attraction

Xu, H., Bohman, B., Wong, D. C. J., Rodriguez-Delgado, C., Scaffidi, A., Flematti, G. R., Phillips, R. D., Pichersky, E. & Peakall, R. 10 Jul 2017 In : Current Biology. 27, 13, p. 1867-1877.e5

Research output: Contribution to journalArticle

citral
citronellol
Biosynthetic Pathways
Deception
geranial
2 Citations

Establishing alighting preferences and species transmission differences for Pea seed-borne mosaic virus aphid vectors

Congdon, B. S., Coutts, B. A., Renton, M., Flematti, G. R. & Jones, R. A. C. 15 Sep 2017 In : Virus Research. 241, p. 145-155 11 p.

Research output: Contribution to journalArticle

Mosaic Viruses
Aphids
Peas
Seeds
Vicia faba

Nickel-Catalyzed C-N Cross-Coupling of Primary Imines with Subsequent InSitu [2+2] Cycloaddition or Alkylation

Power, D. J., Jones, K. D., Kampmann, S. S., Flematti, G. R. & Stewart, S. G. 9 Oct 2017 In : Asian Journal of Organic Chemistry. 6, 12

Research output: Contribution to journalArticle

Imines
Cycloaddition
Alkylation
Nickel
beta-Lactams