Fred Chen

Search results

• 2024

  A multinational survey of potential participant perspectives on ocular gene therapy

  Britten-Jones, A. C., McGuinness, M. B., Chen, F. K., Grigg, J. R., Mack, H. G. & Ayton, L. N., May 2024, In: Gene Therapy. 31, 5-6, p. 314-323 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene Therapy 100%
  • National Eye Institute Visual Function Questionnaire 33%
  • Retina Disease 33%
  • Genetics 28%
  • Attitude 28%

• Analysis of the Outer Retinal Bands in ABCA4 and PRPH2-Associated Retinopathy using OCT

  Heath Jeffery, R. C., Lo, J., Thompson, J. A., Lamey, T. M., McLaren, T. L., De Roach, J. N., Ayton, L. N., Vincent, A. L., Sharma, A. & Chen, F. K., Feb 2024, In: Ophthalmology Retina. 8, 2, p. 174-183 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retinopathy 100%
  • Optical Coherence Tomography 100%
  • Biological Marker 20%
  • Case-Control Study 20%
  4 Citations (Scopus)

• A Precision Therapy Approach for Retinitis Pigmentosa 11 Using Splice-Switching Antisense Oligonucleotides to Restore the Open Reading Frame of PRPF31

  Grainok, J., Pitout, I. L., Chen, F. K., McLenachan, S., Heath Jeffery, R. C., Mitrpant, C. & Fletcher, S., 16 Mar 2024, In: International Journal of Molecular Sciences. 25, 6, 19 p., 3391.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oligonucleotide 100%
  • Antisense 100%
  • Retinitis pigmentosa 100%
  • PRPF31 100%
  • Open Reading Frame 100%

• Bilateral optic atrophy in Wilson disease: A case report and literature review

  Chen, F., Chen, C., Zhang, Y., Jiang, L., Huang, Z. & Chen, F. K., Mar 2024, In: Clinics and Research in Hepatology and Gastroenterology. 48, 3, 102299.

  Research output: Contribution to journal › Article › peer-review

  • Wilson's Disease 100%
  • Optic Nerve Atrophy 100%
  • Optic Neuropathy 37%
  • Clinical Feature 12%
  • Visual Impairment 12%

• Censoring the Floor Effect in Long-Term Stargardt Disease Microperimetry Data Produces a Faster Rate of Decline

  Charng, J., Thompson, J. A., Heath Jeffery, R. C., Kalantary, A., Lamey, T. M., McLaren, T. L. & Chen, F. K., 1 Nov 2024, In: Ophthalmology Science. 4, 6, 100581.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stargardt Disease 100%
  • Scotoma 100%
  • Adenosine Triphosphate 60%
  • Student T Test 40%
  • Cohort Analysis 20%

• Cytokine Levels in Experimental Branch Retinal Vein Occlusion Treated With Either Bevacizumab or Triamcinolone Acetonide

  McAllister, I. L., Vijayasekaran, S., McLenachan, S., Bhikoo, R., Chen, F. K., Zhang, D., Kanagalingam, E. & Yu, D. Y., Jun 2024, In: Translational vision science & technology. 13, 6, 20 p., 13.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytokine 100%
  • Branch Retinal Vein Occlusion 100%
  • Bevacizumab 100%
  • Triamcinolone Acetonide 100%
  • Retinal Vein Occlusion 100%

• Employing texture loss to denoise OCT images using generative adversarial networks

  Mehdizadeh, M., Saha, S., Alonso-Caneiro, D., Kugelman, J., Macnish, C. & Chen, F., 1 Apr 2024, In: Biomedical Optics Express. 15, 4, p. 2262-2280 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Image Reconstruction 100%
  • Generative Adversarial Networks 100%
  • Optical Coherence Tomography 100%
  • de-noising 66%
  • Similarities 50%

• EQ-5D-5L health utility scores in Australian adults with inherited retinal diseases: A cross-sectional survey

  McGuinness, M. B., Ayton, L. N., Schofield, D., Britten-Jones, A. C., Chen, F. K., Grigg, J. R., Qi, Z., Kraindler, J., Shrestha, R. & Mack, H. G., Aug 2024, In: Acta Ophthalmologica. 102, 5, p. e736-e745

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • National Eye Institute Visual Function Questionnaire 100%
  • Retina Disease 100%
  • Cross Sectional Study 100%
  • Quality of Life 100%
  • Visual Analog Scale 50%
  1 Citation (Scopus)

• Establishment of an induced pluripotent stem cell line LEIi019-A from an early-onset retinal dystrophy patient with the autosomal dominant OTX2 c.259G>A variant

  Zhang, D., Jennings, L., Chen, S. C., Zaw, K., Lamey, T. M., Thompson, J. A., McLaren, T. L., Chen, F. K. & McLenachan, S., Aug 2024, In: Stem Cell Research. 78, 5 p., 103461.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Pluripotent Stem Cell 100%
  • Autosomal Dominant Inheritance 100%
  • Stem Cell Line 100%
  • LIN28 33%
  • Reprogramming 33%

• Foveal hypoplasia in a Chinese adolescent with 48, XXYY syndrome

  Chen, C., Guo, S., Huang, Z., Fu, T., Jiang, L. & Chen, F. K., 2024, In: Ophthalmic Genetics. 45, 3, p. 258-261 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Adolescence 100%
  • Hypoplasia 100%
  • Optical Coherence Tomography 50%
  • Optical Coherence Tomography Angiography 50%
  • Sex Chromosome Aberration 33%
  1 Citation (Scopus)

• Generation of two induced pluripotent stem cell lines from an Usher syndrome type 1B patient with the homozygous c.496del MYO7A variant

  Wong, E. Y. M., Khoh, X. E., Chen, S. C., Lye, J., Leith, F. K., Zhang, D., Lamey, T. M., Thompson, J. A., McLaren, T. L., Atlas, M. D., Chen, F. K. & McLenachan, S., Sept 2024, In: Stem Cell Research. 79, 4 p., 103492.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Pluripotent Stem Cell 100%
  • Stem Cell Line 100%
  • MYO7A 100%
  • MicroRNA 33%
  • LIN28 33%

• Is It Possible to Preserve Vision without Compromising Metastases-Free Survival by Use of Fully Fractionated Stereotactic Radiotherapy for Posterior Choroidal Melanoma?

  Phillips, C. E., Youssef, A., Bressel, M., O'Day, R., Sia, J., McKenzie, J. D., McKay, D., Campbell, W. & Chen, F. K., 1 Jun 2024, In: Ocular Oncology and Pathology. 10, 2, p. 72-79 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Stereotactic Radiotherapy 100%
  • Metastasis Free Survival 100%
  • Choroid Melanoma 100%
  • Neoplasm 60%
  • Visual Acuity 60%

• Macular neovascularization in inherited retinal diseases: A review

  Heath Jeffery, R. C. & Chen, F. K., 1 Jan 2024, In: Survey of Ophthalmology. 69, 1, p. 1-23 23 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Retina Disease 100%
  • Neovascularization (Pathology) 100%
  • Vasculotropin 33%
  • Age Related Macular Degeneration 33%
  • Diseases 16%
  3 Citations (Scopus)

• Nonlinear Reduction in Hyperautofluorescent Ring Area in Retinitis Pigmentosa

  Charng, J., Escalona, I. A. V., Turpin, A., McKendrick, A. M., Mackey, D. A., Alonso-Caneiro, D. & Chen, F. K., 4 Mar 2024, (E-pub ahead of print) In: Ophthalmology Retina. 8, 3, p. 298-306 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Retinitis pigmentosa 100%
  • Cohort Analysis 16%
  • Linear Regression Analysis 16%
  • Clinical Trial 16%
  1 Citation (Scopus)

• Non-syndromic OTX2-associated pattern dystrophy: a 10-year multimodal imaging study

  Ramakrishnan, P., Kenworthy, M. K., Alexis, J. A., Thompson, J. A., Lamey, T. M. & Chen, F. K., 18 Jul 2024, (E-pub ahead of print) In: Documenta Ophthalmologica. 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dystrophy 100%
  • Multimodal Imaging 100%
  • Homeobox 100%
  • Orthodenticle Homeobox 2 100%
  • Pigmentation 25%

• Ocular biomarkers: useful incidental findings by deep learning algorithms in fundus photographs

  Martin, E., Cook, A. G., Frost, S. M., Turner, A. W., Chen, F. K., McAllister, I. L., Nolde, J. M. & Schlaich, M. P., Sept 2024, In: Eye (Basingstoke). 38, 13, p. 2581-2588 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Biological Marker 100%
  • Incidental Finding 100%
  • Photograph 100%
  • Diseases 60%
  • Diabetic Retinopathy 60%

• Oral Sirolimus for Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome

  Kalantary, A., Halbert, A., Franchina, M., Heath Jeffery, R. C., O'Day, R. & Chen, F. K., 18 Apr 2024, (E-pub ahead of print) In: JAMA Ophthalmology. 2 p.

  Research output: Contribution to journal › Article › peer-review

• Rapid Variant Pathogenicity Analysis by CRISPR Activation of CRB1 Gene Expression in Patient-Derived Fibroblasts

  Moon, S. Y., Zhang, D., Chen, S. C., Lamey, T. M., Thompson, J. A., McLaren, T. L., Chen, F. K. & McLenachan, S., Apr 2024, In: CRISPR Journal. 7, 2, p. 100-110 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • CRB1 100%
  • CRISPR Activation 100%
  • Gene Expression 100%
  • Fibroblast 100%
  • CRISPR 100%

• Rationale and protocol paper for the Asia Pacific Network for inherited eye diseases

  Wong, W. M., Tham, Y. C., Simunovic, M. P., Chen, F. K., Luu, C. D., Chen, H., Jin, Z. B., Shen, R. J., Li, S., Sui, R., Zhao, C., Yang, L., Bhende, M., Raman, R., Sen, P., Ghosh, A., Poornachandra, B., Sasongko, M. B., Arianti, A., Chia, V., & 41 othersMangunsong, C. O., Manurung, F., Fujinami, K., Ikeda, H., Woo, S. J., Kim, S. J., Mohd Khialdin, S., Othman, O., Bastion, M. L. C., Kamalden, A. T., Lott, P. W. P., Fong, K., Shunmugam, M., Lim, A., Thapa, R., Pradhan, E., Rajkarnikar, S. P., Adhikari, S., Ibañez, B. M. B. IV., Koh, A., Chan, C. M. M., Fenner, B. J., Tan, T. E., Laude, A., Ngo, W. K., Holder, G. E., Su, X., Chen, T. C., Wang, N. K., Kang, E. Y. C., Huang, C. H., Surawatsatien, N., Pisuchpen, P., Sujirakul, T., Kumaramanickavel, G., Singh, M., Leroy, B., Michaelides, M., Cheng, C. Y., Chen, L. J. & Chan, H. W., 1 Jan 2024, In: Asia-Pacific Journal of Ophthalmology. 13, 1, 100030.

  Research output: Contribution to journal › Short survey › peer-review

  Open Access

  • Eye Disease 100%
  • Retina Disease 100%
  • Diseases 25%
  • Patient Care 25%
  • Agents Acting on the Eye 25%

• Retinal Characteristics of Female Choroideremia Carriers: Multimodal Imaging, Microperimetry, and Genetics

  Gocuk, S. A., Edwards, T. L., Jolly, J. K., McGuinness, M. B., MacLaren, R. E., Chen, F. K., Taylor, L. J., McLaren, T. L., Lamey, T. M., Thompson, J. A. & Ayton, L. N., 25 Jun 2024, (Accepted/In press) In: Ophthalmology Retina. 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microperimetry 100%
  • Genetics 100%
  • Visual Acuity 100%
  • Multimodal Imaging 100%
  • Best Corrected Visual Acuity 60%

• Retinal Dystrophies Associated With Peripherin-2: Genetic Spectrum and Novel Clinical Observations in 241 Patients

  Heath Jeffery, R. C., Thompson, J. A., Lo, J., Chelva, E. S., Armstrong, S., Pulido, J. S., Procopio, R., Vincent, A. L., Bianco, L., Battaglia Parodi, M., Ziccardi, L., Antonelli, G., Barbano, L., Marques, J. P., Geada, S., Carvalho, A. L., Tang, W. C., Chan, C. M., Boon, C. J. F., Hensman, J., & 22 othersChen, T-C., Lin, C-Y., Chen, P-L., Vincent, A., Tumber, A., Heon, E., Grigg, J. R., Jamieson, R. V., Cornish, E. E., Nash, B. M., Borooah, S., Ayton, L. N., Britten-Jones, A. C., Edwards, T. L., Ruddle, J. B., Sharma, A., Porter, R. G., Lamey, T. M., McLaren, T. L., McLenachan, S., Roshandel, D. & Chen, F. K., 1 May 2024, In: Investigative ophthalmology & visual science. 65, 5, 17 p., 22.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Clinical Observation 100%
  • Autofluorescence 100%
  • Retina Dystrophy 100%
  • Peripherin 100%
  • Genetics 100%
  1 Citation (Scopus)

• Retreatment interval lengthening achieved in two thirds of eyes with prolonged intensive anti-VEGF therapy for neovascular age-related macular degeneration after switching to faricimab

  Kenworthy, M. K., Alexis, J. A., Ramakrishnan, P. & Chen, F. K., Jul 2024, In: Clinical and Experimental Ophthalmology. 52, 5, p. 589-591 3 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Skin fragility disorder misdiagnosed as child abuse: a cautionary tale

  Mack, H. G., Chen, F. K. & Grigg, J. R., 5 Aug 2024, In: Medical Journal of Australia. 221, 3, p. 171 1 p.

  Research output: Contribution to journal › Letter › peer-review

• The bright future for Clinical and Experimental Ophthalmology in rapidly changing times in scientific publication

  Goggin, M. & Chen, F. K., 1 Jan 2024, In: Clinical and Experimental Ophthalmology. 52, 1, p. 5-6 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
  1 Citation (Scopus)

• Towards standardising retinal OCT angiography image analysis with open-source toolbox OCTAVA

  Untracht, G. R., Durkee, M. S., Zhao, M., Kwok-Cheung Lam, A., Sikorski, B. L., Sarunic, M. V., Andersen, P. E., Sampson, D. D., Chen, F. K. & Sampson, D. M., Dec 2024, In: Scientific Reports. 14, 1, 5979.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Optical Coherence Tomography Angiography 100%
  • Microvessel 8%

• Towards Uncovering the Role of Incomplete Penetrance in Maculopathies through Sequencing of 105 Disease-Associated Genes

  Hitti-Malin, R. J., Panneman, D. M., Corradi, Z., Boonen, E. G. M., Astuti, G., Dhaenens, C. M., Stöhr, H., Weber, B. H. F., Sharon, D., Banin, E., Karali, M., Banfi, S., Ben-Yosef, T., Glavač, D., Farrar, G. J., Ayuso, C., Liskova, P., Dudakova, L., Vajter, M., Ołdak, M., & 40 othersSzaflik, J. P., Matynia, A., Gorin, M. B., Kämpjärvi, K., Bauwens, M., De Baere, E., Hoyng, C. B., Li, C. H. Z., Klaver, C. C. W., Inglehearn, C. F., Fujinami, K., Rivolta, C., Allikmets, R., Zernant, J., Lee, W., Podhajcer, O. L., Fakin, A., Sajovic, J., AlTalbishi, A., Valeina, S., Taurina, G., Vincent, A. L., Roberts, L., Ramesar, R., Sartor, G., Luppi, E., Downes, S. M., van den Born, L. I., McLaren, T. L., De Roach, J. N., Lamey, T. M., Thompson, J. A., Chen, F. K., Tracewska, A. M., Kamakari, S., Sallum, J. M. F., Bolz, H. J., Kayserili, H., Roosing, S. & Cremers, F. P. M., 19 Mar 2024, In: Biomolecules. 14, 3, 20 p., 367.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Penetrance 100%
  • Maculopathy 100%
  • Genetics 75%
  • Proband 25%
  • Genetic Disorder 25%

• Using optical coherence tomography and optical coherence tomography angiography to delineate neurovascular homeostasis in migraine: a review

  Chaliha, D. R., Vaccarezza, M., Charng, J., Chen, F. K., Lim, A., Drummond, P., Takechi, R., Lam, V., Dhaliwal, S. S. & Mamo, J. C. L., 15 Apr 2024, In: Frontiers in Neuroscience. 18, 16 p., 1376282.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Optical Coherence Tomography 100%
  • Homeostasis 100%
  • Migraine 100%
  • Optical Coherence Tomography Angiography 100%
  • Diseases 18%
  1 Citation (Scopus)
• 2023

  Advances towards personalized therapies for Stargardt disease

  Huang, D., McLenachan, S. & Chen, F. K., 2023, In: Expert Review of Ophthalmology. 18, 5, p. 315-325 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Gene Expression 100%
  • Stargardt Disease 100%
  • Personalized Medicine 100%
  • ABCA4 100%
  • Diseases 50%

• Benefits of a Laser Chorioretinal Anastomosis Plus Ranibizumab vs Ranibizumab Alone for Central Retinal Vein Occlusion: 4-Year Results

  Allister, I. L. M., Smithies, L. A., Chen, F. K., Mackey, D. A. & Sanfilippo, P. G., Aug 2023, In: American Journal of Ophthalmology. 252, p. 101-110 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Central Retinal Vein 100%
  • Retinal Vein Occlusion 100%
  • Ranibizumab 100%
  • Anastomosis 100%
  • Central Retina Vein Occlusion 100%

• Deep learning: applications in retinal and optic nerve diseases

  Charng, J., Alam, K., Swartz, G., Kugelman, J., Alonso-Caneiro, D., Mackey, D. & Chen, F., 2023, In: Clinical and Experimental Optometry. 106, 5, p. 466-475 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Deep Learning Method 100%
  • Complex Task 16%
  • Training Process 16%
  • Clinical Data 16%
  • Clinical Application 16%
  3 Citations (Scopus)

• Detection of metastases using circulating tumour DNA in uveal melanoma

  Beasley, A. B., de Bruyn, D. P., Calapre, L., Al-Ogaili, Z., Isaacs, T., Bentel, J., Reid, A. L., Dwarkasing, R. S., Pereira, M. R., Khattak, A., Meniawy, T., Millward, M., Brosens, E., de Klein, A., Chen, F., Kilic, E. & Gray, E. S., Nov 2023, In: Journal of Cancer Research and Clinical Oncology. 149, 16, p. 14953-14963 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metastatic Carcinoma 100%
  • Circulating Tumor DNA 100%
  • Uvea Melanoma 100%
  • Treatment Response 22%
  • Primary Tumor 22%
  2 Citations (Scopus)

• Diabetic Macular Oedema Guidelines: An Australian Perspective

  Yuen, Y. S., Gilhotra, J. S., Dalton, M., Aujla, J. S., Mehta, H., Wickremasinghe, S., Uppal, G., Arnold, J., Chen, F., Chang, A., Fraser-Bell, S., Lim, L., Shah, J., Bowditch, E. & Broadhead, G. K., 2023, In: Journal of Ophthalmology. 2023, 6329819.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Practice Guideline 100%
  • Diabetic Macular Edema 100%
  • Diabetic Retinopathy 66%
  • Visual Impairment 33%
  • Diabetes 33%
  1 Citation (Scopus)

• Diagnosis and Management of Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Delphi Consensus Exercise

  Singh, R. P., Amoaku, W., Bandello, F., Chen, F. K., Holz, F. G., Kodjikian, L., Ruiz-Moreno, J. M., Joshi, P. & Wykoff, C. C., Oct 2023, In: Ophthalmic Surgery Lasers and Imaging Retina. 54, 10, p. 589-598 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Age Related Macular Degeneration 100%
  • Geographic Atrophy 100%
  • Eye Care 50%
  • Nicotine Withdrawal 25%
  • Optical Coherence Tomography 25%
  2 Citations (Scopus)

• Health economic aspects of inherited retinal diseases: looking for cost-effective treatments

  Kamien, B., Heath Jeffery, R. & Chen, F. K., 17 Jul 2023, In: Medical Journal of Australia. 219, 2, p. 61-62 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Incidence and Mortality of Conjunctival Melanoma in Australia (1982 to 2014)

  Beasley, A. B., Preen, D. B., McLenachan, S., Gray, E. S. & Chen, F. K., 1 Nov 2023, In: Investigative ophthalmology & visual science. 64, 14, p. 2 1 p., 2.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Melanoma 100%
  • Confidence Interval 50%
  • Proportional Hazards Model 33%
  • Malignant Neoplasm 16%
  • Eye Melanoma 16%

• Inner Retinal Changes in Acute Experimental BRVO Treated With Bevacizumab or Triamcinolone Acetonide

  McAllister, I. L., Vijayasekaran, S., Bhikoo, R., Chen, F. K., Zhang, D., Kanagalingam, E., McLenachan, S. & Yu, D. Y., 1 Feb 2023, In: Translational Vision Science and Technology. 12, 2, 11.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Branch Retinal Vein Occlusion 100%
  • Bevacizumab 100%
  • Triamcinolone Acetonide 100%
  • Retinal Vein Occlusion 100%
  • Programmed Cell Death 57%
  1 Citation (Scopus)

• Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

  Nguyen, T., Urrutia-Cabrera, D., Wang, L., Lees, J. G., Wang, J. H., Hung, S. S. C., Hewitt, A. W., Edwards, T. L., McLenachan, S., Chen, F. K., Lim, S. Y., Luu, C. D., Guymer, R. & Wong, R. C. B., 16 Feb 2023, In: Aging. 15, 6, p. 1713-1733 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genetic Determinism 100%
  • Expression Quantitative Trait Loci 100%
  • SOD2 100%
  • Genetics 100%
  • Upregulation 100%
  1 Citation (Scopus)

• L-arginine and aged garlic extract for the prevention of migraine: a study protocol for a randomised, double-blind, placebo-controlled, phase-II trial (LARGE trial)

  Chaliha, D. R., Vaccarezza, M., Corti, E., Takechi, R., Dhaliwal, S. S., Drummond, P., Visser, E., Chen, F. K., Charng, J., Lam, V. & Mamo, J. C. L., 27 Mar 2023, In: BMC Neurology. 23, 1, p. 122 1 p., 122.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phase II Trials 100%
  • Migraine 100%
  • Garlic Extract 100%
  • Placebo 100%
  • Arginine 100%

• Longitudinal Analysis of Functional and Structural Outcome Measures in PRPH2-Associated Retinal Dystrophy

  Heath Jeffery, R. C., Thompson, J. A., Lamey, T. M., McLaren, T. L., De Roach, J. N., McAllister, I. L., Constable, I. J. & Chen, F. K., Jan 2023, In: Ophthalmology Retina. 7, 1, p. 81-91 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Autofluorescence 100%
  • Retina Dystrophy 100%
  • Retinal Dystrophy 100%
  • Disease Exacerbation 100%
  • Optical Coherence Tomography 16%
  3 Citations (Scopus)

• Microperimetry and Adaptive Optics Imaging Reveal Localized Functional and Structural Changes in Asymptomatic RPGR Mutation Carriers

  Roshandel, D., Lamey, T. M., Charng, J., Heath Jeffery, R. C., McLaren, T. L., Thompson, J. A., De Roach, J. N., McLenachan, S., Mackey, D. A. & Chen, F. K., Jan 2023, In: Investigative ophthalmology & visual science. 64, 1, p. 3 12 p., 3.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microperimetry 100%
  • Visual Acuity 100%
  • Clinical Assessment 100%
  • Case-Control Study 50%
  • Grid Test 50%
  2 Citations (Scopus)

• Microperimetry Findings in Pentosan Polysulfate Maculopathy

  Most, J., Kalaw, F. G. P., Walker, E., Arias, J. D., Charng, J., Baxter, S. L., Nudleman, E., Ferreyra, H., Freeman, W. R., Chen, F. K. & Borooah, S., Nov 2023, In: Ophthalmology Retina. 7, 11, p. 1022-1024 3 p.

  Research output: Contribution to journal › Article › peer-review

• Mitochondrial Dysfunction and Impaired Antioxidant Responses in Retinal Pigment Epithelial Cells Derived from a Patient with RCBTB1-Associated Retinopathy

  Huang, Z., Zhang, D., Chen, S. C., Huang, D., Mackey, D., Chen, F. K. & McLenachan, S., May 2023, In: Cells. 12, 10, 1358.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antioxidant 100%
  • Epithelial Cell 100%
  • Retinopathy 100%
  • Visual Pigment 100%
  • Mitochondrial Disorder 100%
  3 Citations (Scopus)

• Pearls and Pitfalls of Adaptive Optics Ophthalmoscopy in Inherited Retinal Diseases

  Ashourizadeh, H., Fakhri, M., Hassanpour, K., Masoudi, A., Jalali, S., Roshandel, D. & Chen, F. K., 19 Jul 2023, In: Diagnostics. 13, 14, 2413.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ophthalmoscopy 100%
  • Retina Disease 100%
  • Photoreceptor Cell 100%
  • Retina Dystrophy 50%
  • Retinal Imaging 50%
  1 Citation (Scopus)

• Peripapillary hyperreflective ovoid mass-like structures: Multimodal imaging-A review

  Jeffery, R. C. H. & Chen, F. K., 1 Jan 2023, In: Clinical and Experimental Ophthalmology. 51, 1, p. 67-80 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Optic Nerve 100%
  • Multimodal Imaging 100%
  • Optic Disc 50%
  • Diseases 50%
  • Differential Diagnosis 50%
  13 Citations (Scopus)

• Randomized Phase IIb Study of Brimonidine Drug Delivery System Generation 2 for Geographic Atrophy in Age-Related Macular Degeneration

  BEACON Study Group, Freeman, W. R., Bandello, F., Souied, E., Guymer, R. H., Garg, S. J., Chen, F. K., Rich, R., Holz, F., Patel, S. S. & Kim, K., Jul 2023, In: Ophthalmology Retina. 7, 7, p. 573-585 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Age Related Macular Degeneration 100%
  • Geographic Atrophy 100%
  • Drug Delivery System 100%
  • Brimonidine 100%
  • Intravitreal Administration 20%
  13 Citations (Scopus)

• Recent Therapeutic Progress and Future Perspectives for the Treatment of Hearing Loss

  Lye, J., Delaney, D. S., Leith, F. K., Sardesai, V. S., McLenachan, S., Chen, F. K., Atlas, M. D. & Wong, E. Y. M., Dec 2023, In: Biomedicines. 11, 12, 3347.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Sensorineural Hearing Loss 100%
  • Hearing Loss 100%
  • Cochlea 100%
  • Spiral Ganglion 100%
  • Cell Therapy 100%
  3 Citations (Scopus)

• Reply

  Heath Jeffery, R. C., Lo, J., Thompson, J. A., Lamey, T. M., McLaren, T. L., De Roach, J. N., Ayton, L. N., Vincent, A. L., Sharma, A. & Chen, F. K., Dec 2023, In: Ophthalmology Retina. 7, 12, p. e20-e21

  Research output: Contribution to journal › Letter › peer-review

• RNA-targeting strategies as a platform for ocular gene therapy

  Kumar, S., Fry, L. E., Wang, J. H., Martin, K. R., Hewitt, A. W., Chen, F. K. & Liu, G. S., Jan 2023, In: Progress in Retinal and Eye Research. 92, 28 p., 101110.

  Research output: Contribution to journal › Review article › peer-review

  • Eye Disease 100%
  • Gene Therapy 100%
  • Clustered Regularly Interspaced Short Palindromic Repeat 100%
  • Antisense Oligonucleotide 66%
  • Complementary RNA 66%
  19 Citations (Scopus)

• Serum miRNA modulations indicate changes in retinal morphology

  Aggio-Bruce, R., Schumann, U., Cioanca, A. V., Chen, F. K., McLenachan, S., Heath Jeffery, R. C., Das, S. & Natoli, R., 3 Mar 2023, In: Frontiers in Molecular Neuroscience. 16, 15 p., 1130249.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • microRNA 100%
  • Morphology 100%
  • Mouse Model 100%
  • MicroRNA 100%
  • Age Related Macular Degeneration 55%
  1 Citation (Scopus)

• Survey of perspectives of people with inherited retinal diseases on ocular gene therapy in Australia

  Mack, H. G., Britten-Jones, A. C., McGuinness, M. B., Chen, F. K., Grigg, J. R., Jamieson, R. V., Edwards, T. L., De Roach, J., O'Hare, F., Martin, K. R. & Ayton, L. N., Apr 2023, In: Gene Therapy. 30, 3-4, p. 336-346 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retina Disease 100%
  • Gene Therapy 100%
  • Quality of Life 100%
  • Attitude 40%
  • National Eye Institute Visual Function Questionnaire 27%
  7 Citations (Web of Science)