Florian Zepf

Professor

  • The University of Western Australia (000), 35 Stirling Highway,

    6009 Perth

    Australia

  • 945 Citations
  • 16 h-Index
20072019
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Research Output 2007 2019

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Article
2019

Child and adolescent psychiatry training in Australia and New Zealand

Rao, P., Caunt, J. N., Wong, J. W. Y., Moore, J. K. & Zepf, F. D., 22 Oct 2019, In : European Child and Adolescent Psychiatry.

Research output: Contribution to journalArticle

Adolescent Psychiatry
Child Psychiatry
New Zealand
Psychiatry
Education
1 Citation (Scopus)

Concurrent developmental course of sleep problems and emotional/behavioral problems in childhood and adolescence as reflected by the dysregulation profile

Wang, B., Eastwood, P. R., Becker, A., Isensee, C., Wong, J. W. Y., Huang, R. C., Runions, K. C., Stewart, R. M., Meyer, T., Brüni, L. G., Rothenberger, A. & Zepf, F. D., 19 Mar 2019, In : Sleep. 42, 3, zsy243.

Research output: Contribution to journalArticle

Open Access
Sleep
Aggression
Psychopathology
Cognition
Patient Care
6 Citations (Scopus)

Serotonergic Contributions to Human Brain Aggression Networks

Klasen, M., Wolf, D., Eisner, P. D., Eggermann, T., Zerres, K., Zepf, F. D., Weber, R. & Mathiak, K., 22 Feb 2019, In : Frontiers in Neuroscience. 13, 11 p., 42.

Research output: Contribution to journalArticle

Open Access
2018
5 Citations (Scopus)

Central serotonin modulates neural responses to virtual violent actions in emotion regulation networks

Wolf, D., Klasen, M., Eisner, P., Zepf, F. D., Zvyagintsev, M., Palomero-Gallagher, N., Weber, R., Eisert, A. & Mathiak, K., 1 Sep 2018, In : Brain Structure and Function. 223, 7, p. 3327-3345 19 p.

Research output: Contribution to journalArticle

Serotonin
Emotions
Serotonin Receptors
Gyrus Cinguli
Prefrontal Cortex

Effects of dietary acute tryptophan depletion (ATD) on NPY serum levels in healthy adult humans whilst controlling for methionine supply—a pilot study

Wong, J. W. Y., Morandini, H. A. E., Dingerkus, V. L. S., Gaber, T. J., Runions, K. C., Rao, P., Mahfouda, S., Helmbold, K., Bubenzer-Busch, S., Koenemann, R., Stewart, R. M. & Zepf, F. D., 11 May 2018, In : Nutrients. 10, 5, 12 p., 594.

Research output: Contribution to journalArticle

Open Access
neuropeptide Y
Neuropeptide Y
blood serum
serotonin
Tryptophan
9 Citations (Scopus)

Neural networks underlying trait aggression depend on MAOA gene alleles

Klasen, M., Wolf, D., Eisner, P. D., Habel, U., Repple, J., Vernaleken, I., Schlüter, T., Eggermann, T., Zerres, K., Zepf, F. D. & Mathiak, K., 1 Mar 2018, In : Brain Structure and Function. 223, 2, p. 873-881 9 p.

Research output: Contribution to journalArticle

Aggression
Alleles
Parietal Lobe
Prefrontal Cortex
Genes
1 Citation (Scopus)

No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults

Hildebrandt, C. S., Helmbold, K., Linden, M., Langen, K. J., Filss, C. P., Runions, K. C., Stewart, R. M., Rao, P., Moore, J. K., Mahfouda, S., Morandini, H. A. E., Wong, J. W. Y., Rink, L. & Zepf, F. D., 26 Apr 2018, In : The World Journal of Biological Psychiatry. p. 1-8 8 p.

Research output: Contribution to journalArticle

Tryptophan
Immune System
Cytokines
Serotonin
Dimercaprol
2017
10 Citations (Scopus)

Cortico-limbic connectivity in MAOA-L carriers is vulnerable to acute tryptophan depletion

Eisner, P., Klasen, M., Wolf, D., Zerres, K., Eggermann, T., Eisert, A., Zvyagintsev, M., Sarkheil, P., Mathiak, K. A., Zepf, F. & Mathiak, K., 1 Mar 2017, In : Human Brain Mapping. 38, 3, p. 1622-1635 14 p.

Research output: Contribution to journalArticle

Monoamine Oxidase
Tryptophan
Serotonin
Amygdala
Prefrontal Cortex
2 Citations (Scopus)

Differences in serum zinc levels in acutely ill and remitted adolescents and young adults with bulimia nervosa in comparison with healthy controls - a cross-sectional pilot study

Zepf, F. D., Rao, P., Runions, K., Stewart, R. M., Moore, J. K., Wong, J. W. Y., Linden, M., Sungurtekin, I., Glass, F., Gut, L., Peetz, D., Hintereder, G., Schaab, M., Poustka, F. & Wöckel, L., 17 Oct 2017, In : Neuropsychiatric Disease and Treatment. 13, p. 2621-2630 10 p.

Research output: Contribution to journalArticle

Open Access
Bulimia Nervosa
Zinc
Young Adult
Cross-Sectional Studies
Serum
1 Citation (Scopus)
Open Access
Neurofeedback
Attention Deficit Disorder with Hyperactivity
Neuropsychological Tests
Reaction Time
Education
2 Citations (Scopus)

Functional connectivity of the vigilant-attention network in children and adolescents with attention-deficit/hyperactivity disorder

Zepf, F. D., Bubenzer-Busch, S., Runions, K. C., Rao, P., Wong, J. W. Y., Mahfouda, S., Morandini, H. A. E., Stewart, R. M., Moore, J. K., Biskup, C. S., Eickhoff, S. B., Fink, G. R. & Langner, R., 14 Nov 2017, In : Brain and Cognition.

Research output: Contribution to journalArticle

Open Access
Attention Deficit Disorder with Hyperactivity
Brain
Aptitude
Attention Deficit Hyperactivity Disorder
Connectivity
Open Access
Serotonin Uptake Inhibitors
Nitrous Oxide
Antidepressive Agents
Randomized Controlled Trials
Depression
2016
Open Access
Adolescent Health Services
National Health Programs
Mental Health Services
Antipsychotic Agents
Minors
15 Citations (Scopus)

A web-based teaching module on the administration of EEG-based neurofeedback for the treatment of ADHD

Knospe, E. L., Gaber, T. J., Abetz, P., Wong, J. W. & Zepf, F. D., 2016, In : Translational Developmental Psychiatry. 4, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
Minors
Bipolar Disorder
Germany
Inpatients
Mental Disorders
20 Citations (Scopus)

Developmental trajectories of sleep problems from childhood to adolescence both predict and are predicted by emotional and behavioral problems

Wang, B., Isensee, C., Becker, A., Wong, J., Eastwood, P. R., Huang, R-C., Runions, K. C., Stewart, R. M., Meyer, T., G. Brüni, L., Zepf, F. D. & Rothenberger, A., 2016, In : Frontiers in Psychology. 7, DEC, 1874.

Research output: Contribution to journalArticle

Open Access
Sleep
Anxiety
Depression
Problem Behavior
Growth
3 Citations (Scopus)

Dietary tryptophan depletion in humans using a simplified two amino acid formula - a pilot study

Linden, M., Helmbold, K., Kempf, J., Sippas, S., Filss, C., Langen, K-J., Eisert, A. & Zepf, F. D., 2016, In : Food and Nutrition Research. 60, p. 29272

Research output: Contribution to journalArticle

Open Access
Tryptophan
tryptophan
Amino Acids
amino acids
blood-brain barrier
3 Citations (Scopus)
11 Downloads (Pure)

Effects of music and natural science training on aggressive behavior

Roden, I., Zepf, F. D., Kreutz, G., Grube, D. & Bongard, S., 1 Oct 2016, In : Learning and Instruction. 45, p. 85-92 8 p.

Research output: Contribution to journalArticle

Natural Science Disciplines
aggressive behavior
natural sciences
Music
music
4 Citations (Scopus)
Leptin Receptors
Adipokines
Human Milk
Leptin
Energy Intake

Integrity of Amygdala Subregion-Based Functional Networks and Emotional Lability in Drug-Naïve Boys With ADHD

Yu, X., Liu, L., Chen, W., Cao, Q., Zepf, F. D., Ji, G., Wu, Z., An, L., Wang, P., Qian, Q., Zang, Y., Sun, L. & Wang, Y., 2016, In : Journal of Attention Disorders. 13 p.

Research output: Contribution to journalArticle

Amygdala
Pharmaceutical Preparations
Parietal Lobe
Temporal Lobe
Prefrontal Cortex
11 Citations (Scopus)

Neural correlates of reactive aggression in children with attention-deficit/hyperactivity disorder and comorbid disruptive behaviour disorders

Bubenzer-Busch, S., Herpertz-Dahlmann, B., Kuzmanovic, B., Gaber, T. J., Helmbold, K., Ullisch, M. G., Baurmann, D., Eickhoff, S. B., Fink, G. R. & Zepf, F., 2016, In : Acta Psychiatrica Scandinavica. 133, 4, p. 310-323

Research output: Contribution to journalArticle

Attention Deficit and Disruptive Behavior Disorders
Attention Deficit Disorder with Hyperactivity
Aggression
Impulsive Behavior
Magnetic Resonance Imaging
10 Citations (Scopus)

Resting state default mode network connectivity in children and adolescents with ADHD after acute tryptophan depletion

Biskup, C. S., Helmbold, K., Baurmann, D., Klasen, M., Gaber, T. J., Bubenzer-Busch, S., Königschulte, W., Fink, G. R. & Zepf, F., 2016, In : Acta Psychiatrica Scandinavica. 134, 2, p. 161-171

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Tryptophan
Serotonin
Dimercaprol
Nuclear Family
11 Citations (Scopus)

Serotonergic modulation of resting state default mode network connectivity in healthy women

Helmbold, K., Zvyagintsev, M., Dahmen, B., Biskup, C. S., Bubenzer-Busch, S., Gaber, T. J., Klasen, M., Eisert, A., Konrad, K., Habel, U., Herpertz-Dahlmann, B. & Zepf, F., 2016, In : Amino Acids. 48, 4, p. 1109-1120

Research output: Contribution to journalArticle

Tryptophan
Serotonin
Modulation
Impulsive Behavior
Frontal Lobe
2015
13 Citations (Scopus)

Amino acid challenge and depletion techniques in human functional neuroimaging studies: an overview

Biskup, C. S., Gaber, T., Helmbold, K., Bubenzer-Busch, S. & Zepf, F., 2015, In : Amino Acids. 47, 4, p. 651-683

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cognitive and neural strategies during control of the anterior cingulate cortex by fMRI neurofeedback in patients with schizophrenia

Cordes, J. S., Mathiak, K. A., Dyck, M., Alawi, E. M., Gaber, T. J., Zepf, F., Klasen, M., Zvyagintsev, M., Gur, R. C. & Mathiak, K., 2015, In : Frontiers in Behavioral Neuroscience. 9, p. Article 169

Research output: Contribution to journalArticle

Open Access
Neurofeedback
Gyrus Cinguli
Schizophrenia
Magnetic Resonance Imaging
Imagination
5 Citations (Scopus)

Effects of a short-term reduction in brain serotonin synthesis on the availability of the soluble leptin receptor in healthy women

Zepf, F. D., Dingerkus, V. L. S., Helmbold, K., Bubenzer-Busch, S., Biskup, C. S., Herpertz-Dahlmann, B., Schaab, M., Kratzsch, J., Eisert, A., Rink, L., Hagenah, U. & Gaber, T. J., Mar 2015, In : Journal of Neural Transmission. 122, 3, p. 343-348 6 p.

Research output: Contribution to journalArticle

Leptin Receptors
Serotonin
Brain
Appetite Regulation
Leptin
9 Citations (Scopus)

Effects of dietary tryptophan and phenylalanine-tyrosine depletion on phasic alertness in healthy adults - A pilot study

Hildebrand, P., Königschulte, W., Gaber, T. J., Bubenzer-Busch, S., Helmbold, K., Biskup, C. S., Langen, K. J., Fink, G. R. & Zepf, F., 2015, In : Food and Nutrition Research. 59, p. 1-11

Research output: Contribution to journalArticle

Open Access
dopamine
Phenylalanine
phenylalanine
Tryptophan
tryptophan
19 Citations (Scopus)

Effects of serotonin depletion on punishment processing in the orbitofrontal and anterior cingulate cortices of healthy women

Helmbold, K., Zvyagintsev, M., Dahmen, B., Bubenzer-Busch, S., Gaber, T. J., Crockett, M. J., Klasen, M., Sanchez, C. L., Eisert, A., Konrad, K., Habel, U., Hepertz-Dahlmann, B. & Zepf, F., 2015, In : European Neuropsychopharmacology. 2015, 6, p. 846–856

Research output: Contribution to journalArticle

6 Citations (Scopus)

Reduced Responsiveness to Social Provocation in Autism Spectrum Disorder

Schneider, I., Regenbogen, C., Kohn, N., Zepf, F., Bubenzer-Busch, S., Schneider, F., Gur, R. C. & Habel, U., 2015, In : Autism Research. 8, 3, p. 297-306

Research output: Contribution to journalArticle

9 Citations (Scopus)

Simplified dietary acute tryptophan depletion: Effects of a novel amino acid mixture on the neurochemistry of C57BL/6J mice

Sánchez, C. L., Van Swearingen, A. E. D., Arrant, A. E., Biskup, C. S., Kuhn, C. M. & Zepf, F., 2015, In : Food and Nutrition Research. 59, p. 27424

Research output: Contribution to journalArticle

Open Access
Neurochemistry
Inbred C57BL Mouse
Tryptophan
tryptophan
Amino Acids
17 Citations (Scopus)

Social reward improves the voluntary control over localized brain activity in fMRI-based neurofeedback training

Mathiak, K. A., Alawi, E. M., Koush, Y., Dyck, M., Cordes, J. S., Gaber, T. J., Zepf, F., Palomero-Gallagher, N., Sarkheil, P., Bergert, S., Zvyagintsev, M. & Mathiak, K., 2015, In : Frontiers in Behavioral Neuroscience. 9, JUNE, p. 1-14

Research output: Contribution to journalArticle

Open Access
Neurofeedback
Reward
Magnetic Resonance Imaging
Gyrus Cinguli
Brain
6 Citations (Scopus)

Studying the effects of dietary body weight-adjusted acute tryptophan depletion on punishment-related behavioral inhibition

Gaber, T. J., Dingerkus, V. L. S., Crockett, M. J., Bubenzer-Busch, S., Helmbold, K., Sánchez, C. L., Dahmen, B., Herpertz-Dahlmann, B. & Zepf, F., 2015, In : Food and Nutrition Research. 59, p. 1-11

Research output: Contribution to journalArticle

Open Access
Punishment
Tryptophan
tryptophan
Body Weight
serotonin
10 Citations (Scopus)

The Role of Serotonin (5-HT) in Behavioral Control: Findings from Animal Research and Clinical Implications

Sanchez, C. L., Biskup, C. S., Herpertz, S., Gaber, T. J., Kuhn, C. M., Hood, S. H. & Zepf, F. D., 19 May 2015, In : International Journal of Neuropsychopharmacology. 18, 10, p. 1-3 pyv050.

Research output: Contribution to journalArticle

Open Access
Serotonin
Dopamine
Tryptophan
Neurobiology
Research
2014
9 Citations (Scopus)

Change in electrodermal activity after acute tryptophan depletion associated with aggression in young people with attention deficit hyperactivity disorder (ADHD)

Von Polier, G. G., Biskup, C. S., Kötting, W. F., Bubenzer, S., Helmbold, K., Eisert, A., Gaber, T. J. & Zepf, F., 2014, In : Journal of Neural Transmission. 121, p. 451-455

Research output: Contribution to journalArticle

9 Citations (Scopus)

Dietary manipulation of serotonergic and dopaminergic function in C57BL/6J mice with amino acid depletion mixtures

Sánchez, C. L., Van Swearingen, A. E. D., Arrant, A. E., Kuhn, C. M. & Zepf, F., 2014, In : Journal of Neural Transmission. 121, 2, p. 153-162

Research output: Contribution to journalArticle

14 Citations (Scopus)

Self-perceived stigmatization in female patients with anorexia nervosa - Results from an explorative retrospective pilot study of adolescents

Maier, A., Ernst, J-P., Müller, S., Gross, D., Zepf, F., Herpertz-Dahlmann, B. & Hagenah, U., 2014, In : Psychopathology. 47, p. 127-132

Research output: Contribution to journalArticle

2013
36 Citations (Scopus)

Effects of tryptophan depletion on reactive aggression and aggressive decision-making in young people with ADHD

Kotting, W. F., Bubenzer, S., Helmbold, K., Eisert, A., Gaber, T. J. & Zepf, F., 2013, In : Acta Psychiatrica Scandinavica. 128, p. 114-123

Research output: Contribution to journalArticle

13 Citations (Scopus)

Migration background and juvenile mental health:a descriptive retrospective analysis of diagnostic rates of psychiatric disorders in young people

Gaber, T. J., Bouyrakhen, S., Herpertz-Dahlmann, B., Hagenah, U., Holtmann, M., Freitag, C. M., Wockel, L., Poustka, F. & Zepf, F., 2013, In : GLOBAL HEALTH ACTION. Supplement. 6, p. 1-12

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

No clear effects of acute tryptophan depletion on processing affective prosody in male adults with ADHD

Grabemann, M., Mette, C., Zimmermann, M., Heinrich, V., Uekermann, J., Wiltfang, J., Abdel-Hamid, M., Zepf, F. D. & Kis, B., Aug 2013, In : Acta Pyschiatrica Scandinavica. 128, 2, p. 142-148 7 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Tryptophan
Serotonin
Semantics
Aptitude
13 Citations (Scopus)

No effect of acute tryptophan depletion on verbal declarative memory in young persons with ADHD

Zepf, F., Landgraf, M., Biskup, C. S., Dahmen, B., Poustka, F., Wockel, L. & Stadler, C., 2013, In : ACTA PAEDIATRICA SCANDINAVICA. 128, p. 133-141

Research output: Contribution to journalArticle

7 Citations (Scopus)

Severe affective and behavioral dysregulation in youths is associated with a proinflammatory state

Holtmann, M., Poustka, L., Zepf, F. D., Banaschewski, T., Priller, J., Bölte, S. & Legenbauer, T., Nov 2013, In : Zeitschrift fuer Kinder- und Jugendpsychiatrie und Psychotherapie. 41, 6, p. 393–399 7 p.

Research output: Contribution to journalArticle

Child Behavior
Checklist
C-Reactive Protein
Albumins
Disease Susceptibility
26 Citations (Scopus)

The impact of acute tryptophan depletion on attentional performance in adult patients with ADHD

Mette, C., Zimmermann, M., Grabemann, M., Abdel-Hamid, M., Uekermann, J., Biskup, C. S., Wiltfang, J., Zepf, F. & Kis, B., 2013, In : Acta Psychiatrica Scandinavica. 128, p. 124-132

Research output: Contribution to journalArticle

2012
37 Citations (Scopus)

Acute tryptophan depletion in accordance with body weight: influx of amino acids across the blood–brain barrier

Dingerkus, V. L. S., Gaber, T. J., Helmhold, K., Bubenzer, S., Eisert, A., Sanchez, C. L. & Zepf, F., 2012, In : Journal of Neural Transmission. 119, p. 1037-1045

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Attentional Performance, Age and Scholastic Achievement in Healthy Children

Trautmann, M. & Zepf, F., 2012, In : PLoS One. 7, 3, p. e32279

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Differences in Serum Zn Levels in Acutely Ill and Recovered Adolescents and Young Adults with Anorexia Nervosa – A Pilot Study

Zepf, F., Sungurtekin, I., Glass, F., Elstrodt, L., Peetz, D., Hintereder, G., Kratzsch, J., Poustka, F., Herpetz-Dahlmann, B. & Wockel, L., 2012, In : European Eating Disorders Review. 20, p. 203-210

Research output: Contribution to journalArticle

5 Citations (Scopus)

Differences in zinc status and the leptin axis in anorexic and recovered adolescents and young adults: a pilot study

Zepf, F., Sungurtekin, I., Glass, F., Elstrodt, L., Peetz, D., Hintereder, G., Kratzsch, J., Biskup, C. S., Poustka, F. & Wockel, L., 2012, In : Food and Nutrition Research. 56, p. 1-8

Research output: Contribution to journalArticle

Open Access
50 Citations (Scopus)

Effects of Acute Tryptophan Depletion on Brain Serotonin Function and Concentrations of Dopamine and Norepinephrine in C57BL/6J and BALB/cJ Mice

Biskup, C. S., Sanchez, C. L., Arrant, A., Van Swearingen, A. E. D., Kuhn, C. & Zepf, F., 2012, In : PLoS One. 7, 5, p. e35916

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

The Effects of Acute Tryptophan Depletion on Reactive Aggression in Adults with Attention-Deficit/Hyperactivity Disorder (ADHD) and Healthy Controls

Zimmermann, M., Grabemann, M., Mette, C., Abdel-Hamid, M., Ueckermann, J., Kraemer, M., Wiltfang, J., Kis, B. & Zepf, F., 2012, In : PLoS One. 7, 3, p. e32023

Research output: Contribution to journalArticle

Open Access