• The University of Western Australia (M503), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1412 Citations
  • 24 h-Index
20052019
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Personal profile

Roles and responsibilities

Current Positions:

2015 - Heart Foundation Future Leader Fellow; School of Medicine and Pharmacology, UWA
2013 – Invited Visiting Researcher; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University


Previous Positions:

2005 Teaching Intern; School of Medicine and Pharmacology, UWA
2007 Unilever Postdoctoral Fellow; School of Medicine and Pharmacology, UWA; Unilever Colworth, UK
2008 – 2009 National Heart Foundation Postdoctoral Research Fellow; School of Medicine and Pharmacology, UWA
2008 – 2010 Development and Communication of Research Course Controller, UWA
2008 – 2010 Masters of Clinical Research Coordinator, UWA
2010 A & A Saw Medical Research Fellowship, UWA
2010 – 2012 Visiting Postdoctoral Research Fellow, Jean Mayer USDA Human Nutrition Research Center on Ageing, Tufts University, Boston MA, USA
2010 – 2012 Visiting Postdoctoral Research Fellow, Department of Nutrition, Harvard University, Boston MA, USA
2010 – 2014 National Health and Medical Research Council (NHMRC) CJ Martin Early Career Fellow; School of Medicine and Pharmacology, UWA

Funding overview

Current Funding:

Pathophysiology and Therapeutic Regulation of Lipid Disorders in Subjects at High Cardiovascular Disease Risk; NHF Future Leader Fellowships (2015-2018) [CIA]
Lipoprotein(a) metabolism in subjects at high risk of cardiovascular disease; NHMRC Project Grant ($668,434; 2014-16) [CIA]


Pervious Funding:

NHMRC
Reducing cardiovascular risk in the metabolic syndrome and type 2 diabetes: novel approaches to studies of lipoprotein metabolism; NHMRC Project Grant ($527,275; 2008-9) [AI]
Novel approaches to studies of lipoprotein metabolism; NHMRC training fellowship ($336,170; 2010-2014) [CIA]
Niacin reduces Lp(a) in type 2 diabetes; NHMRC Project Grant ($354,920; 2012-14) [CID]

NHF
Coordinated regulation and function of apoC-III in obesity; NHF Grant-In-Aid ($98,788; 2008-9) [AI]
National Heart Foundation Postdoctoral Fellowship ($131,500; 2008-9) [CIA]
ApoC-III as a regulator of fatty acid and lipoprotein metabolism in women: understanding dyslipidemia as a cardiovascular risk factor; NHF Grant-In-Aid ($127,404; 2008-9) [CIC]

Raine Medical Research Foundation
A systems biology approach to study the coordinate regulation and function of apolipoprotein C-III in the metabolic syndrome; Raine Priming Grant ($183,361; 2008-9) [CIA]

University of Western Australia
A & A Saw Medical Research Fellowship ($145,074; 2010-11)[CIA]
Kinetic Defects in Lipoprotein Metabolism in Patients with Chronic Renal Failure; UWA Research Grant (A$27,600; 2008) [CIA]

Royal Perth Hospital Medical Research Foundation
ApoC-II as a regulator of fatty acid and lipoprotein metabolism in women: understanding dyslipidemia as a cardiovascular risk factor, Medical Research Foundation Grant ($16,500; 2013) [CIA]

Research

My vision for the next 4 years is to establish and undertake a dynamic, innovative research program focused on a new CVD risk factor, lipoprotein(a) [Lp(a)], a quantitative genetic trait that independently raises the risk of premature cardiovascular disease, which directly impacts clinical care of patients in cardiometabolic services at Perth hospitals. The significance and relevance of my research program is underscored by the knowledge that dyslipidemia, a consequence of abnormal lipid and lipoprotein regulation, is a powerful causal risk factor for cardiovascular disease, a leading cause of death in Australia. New knowledge from my research will impact on treatment strategies for dyslipidemia and consequently, cardiovascular risk.
Overarching research interest: Pathogenesis, diagnosis and treatment of hyperlipidemias, atherosclerosis and cardiovascular disease.
Specific research interest: Metabolic studies; the application of stable isotope tracer methods to study the physiology and pathophysiology of lipoprotein metabolism in humans. These include studies of the role of therapeutic, dietary and lifestyle interventions in the regulation of the lipoprotein system in healthy individuals and populations at high-risk of cardiovascular disease (obesity, type 2 diabetes, non-alcoholic liver disease, genetic hyperlipidemias).

Keywords

  • Lipid metabolism
  • Systems biology

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2019

Association Between Plasma Neutrophil Gelatinase-Associated Lipocalin and Cardiac Disease Hospitalizations and Deaths in Older Women

Chong, J. J. H., Prince, R. L., Thompson, P. L., Thavapalachandran, S., Ooi, E., Devine, A., Lim, E. E. M., Byrnes, E., Wong, G., Lim, W. H. & Lewis, J. R., 8 Jan 2019, In : Journal of the American Heart Association. 8, 1, p. e011028

Research output: Contribution to journalArticle

Open Access
Coronary Disease
Heart Diseases
Hospitalization
Heart Failure
Biomarkers
Blood Component Removal
Lipoprotein(a)
Apolipoproteins B
LDL Lipoproteins
Metabolism
1 Citation (Scopus)
Apoprotein(a)
Lipoprotein(a)
Carotid Stenosis
Kringles
Coronary Artery Disease
5 Citations (Scopus)

Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatin

Thongtang, N., Diffenderfer, M. R., Ooi, E. M. M., Barrett, P. H. R., Turner, S. M., Le, N-A., Brown, W. V. & Schaefer, E. J., Jul 2017, In : Journal of Lipid Research. 58, 7, p. 1315-1324 10 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Metabolism
Proteomics
Apolipoprotein B-100
Lipoproteins

Projects 2008 2018

Activities 2014 2014

  • 1 Editorial activity

Nutrition, Metabolism and Cardiovascular Diseases (Journal)

Esther Ooi (Reviewer)
2014

Activity: Editorial work or peer review of publicationsEditorial activity