Eng Chua

Dr, BSc PhD W.Aust.

  • The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth

    Australia

  • 114 Citations
  • 6 h-Index
20112019
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Personal profile

Biography

Dr Chua completed his PhD degree in Microbiology at UWA. His research interest is primarily focused on understanding the molecular mechanisms of bacterial pathogenesis and host-pathogen interaction. The microrganisms he had worked on include Helicobacter pylori, Burkholderia pseudomallei and Shigella flexneri. Dr Chua also has substantial experience in comparative genomics, transcriptomics and metagenomics analyses.

Roles and responsibilities

Perform computational analysis and interpretation of genomics, transcriptomics and metagenomics datasets to investigate the pathogenesis and evolutionary biology of Helicobacter species.

Teach and supervise new researchers and students in the use of computational research and molecular biology approaches relevant to his/her project.

Research

Bacterial pathogenesis
Genomics

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Helicobacter pylori Medicine & Life Sciences
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Microbiota Medicine & Life Sciences
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Research Output 2011 2019

  • 114 Citations
  • 6 h-Index
  • 16 Article
  • 1 Comment/debate
  • 1 Doctoral Thesis
Open Access
Metronidazole
Helicobacter pylori
Proteins
biotin carboxylase
Sequence Alignment

Gastric Helicobacter pylori infection perturbs human oral microbiota

Chua, E. G., Chong, J. Y., Lamichhane, B., Webberley, K. M., Marshall, B. J., Wise, M. J. & Tay, C. Y., 28 Jan 2019, In : PEERJ. 7, 14 p., e6336.

Research output: Contribution to journalArticle

Open Access
Helicobacter pylori
Microbiota
Helicobacter Infections
Urea
mouth

Draft genome sequences of 42 Helicobacter pylori isolates from rural regions of South India

Shetty, V., Lamichhane, B., Chua, E. G., Ballal, M. & Tay, C. Y., 1 Feb 2018, In : Genome Announcements. 6, 5, e01486-17.

Research output: Contribution to journalArticle

Open Access
Helicobacter pylori
India
Genome
Molecular Evolution
Rural Population

Metabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa

Loke, M. F., Chua, E. G., Gan, H. M., Thulasi, K., Wanyiri, J. W., Thevambiga, I., Goh, K. L., Wong, W. F. & Vadivelu, J., 1 Dec 2018, In : PLoS One. 13, 12, e0208584.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Biosynthesis
metabolomics
colorectal neoplasms
mucosa
5 Citations

Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection

Debowski, A. W., Walton, S. M., Chua, E-G., Tay, A. C-Y., Liao, T., Lamichhane, B., Himbeck, R., Stubbs, K. A., Marshall, B. J., Fulurija, A. & Benghezal, M., Jun 2017, In : PLoS Pathogens. 13, 6, 21 p., 1006464.

Research output: Contribution to journalArticle

Open Access